Muc3a (mucin 3A, cell surface associated) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Muc3a (mucin 3A, cell surface associated) Mus musculus
Analyze
Symbol: Muc3a
Name: mucin 3A, cell surface associated
RGD ID: 1619574
MGI Page MGI
Description: Predicted to be involved in cell projection morphogenesis. Predicted to be active in synapse. Orthologous to several human genes including MUC3A (mucin 3A, cell surface associated).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A630081J09Rik; mucin-3A; mucin-3B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,243,263 - 137,276,564 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,243,270 - 137,246,852 (-)EnsemblGRCm39 Ensembl
GRCm385137,208,805 - 137,212,545 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,208,813 - 137,212,389 (-)EnsemblGRCm38mm10GRCm38
Celera5134,230,734 - 134,240,608 (-)NCBICelera
Cytogenetic Map5G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21873635  


Genomics

Comparative Map Data
Muc3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,243,263 - 137,276,564 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,243,270 - 137,246,852 (-)EnsemblGRCm39 Ensembl
GRCm385137,208,805 - 137,212,545 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,208,813 - 137,212,389 (-)EnsemblGRCm38mm10GRCm38
Celera5134,230,734 - 134,240,608 (-)NCBICelera
Cytogenetic Map5G2NCBI
MUC3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,949,534 - 100,968,347 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,949,534 - 100,968,347 (+)EnsemblGRCh38hg38GRCh38
GRCh377100,547,166 - 100,611,620 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,389,076 - 100,398,339 (+)NCBINCBI36Build 36hg18NCBI36
Celera795,277,878 - 95,298,517 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef795,176,179 - 95,179,251 (+)NCBIHuRef
HuRef795,179,408 - 95,187,811 (+)NCBIHuRef
CHM1_17100,477,676 - 100,541,653 (+)NCBICHM1_1
T2T-CHM13v2.07102,189,627 - 102,215,508 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,906,691 - 99,912,723 (+)NCBI
CRA_TCAGchr7v2799,964,439 - 99,970,006 (+)NCBI
Muc3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81225,082,728 - 25,091,494 (+)NCBIGRCr8
mRatBN7.21219,450,679 - 19,454,753 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.01222,501,657 - 22,505,712 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01224,517,500 - 24,519,325 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1221,247,977 - 21,254,491 (+)NCBICelera
Cytogenetic Map12q12NCBI
Muc3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495557345,920 - 60,091 (-)NCBIChiLan1.0ChiLan1.0
MUC3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,850,442 - 118,872,548 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17167,115,071 - 167,137,177 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,974,006 - 92,993,990 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,386,635 - 106,392,357 (+)NCBIpanpan1.1PanPan1.1panPan2
LOC101963142
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,130,911 - 133,134,822 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936543886,333 - 904,504 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC103246941
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,225,743 - 12,267,857 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666973598 - 25,017 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Muc3a
422 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:537
Count of miRNA genes:365
Interacting mature miRNAs:388
Transcripts:ENSMUST00000179412
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119945037149347326Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse
13464143Bbaa2b_mB.burgdorferi-associated arthritis 2b (mouse)5133052969140709801Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5133925558151758149Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000179412   ⟹   ENSMUSP00000136061
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,243,270 - 137,246,852 (-)Ensembl
GRCm38.p6 Ensembl5137,208,813 - 137,212,389 (-)Ensembl
RefSeq Acc Id: ENSMUST00000196391   ⟹   ENSMUSP00000143027
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,243,270 - 137,246,611 (-)Ensembl
GRCm38.p6 Ensembl5137,208,813 - 137,212,148 (-)Ensembl
RefSeq Acc Id: XM_036165654   ⟹   XP_036021547
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,243,263 - 137,259,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165655   ⟹   XP_036021548
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,243,263 - 137,259,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165656   ⟹   XP_036021549
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,243,263 - 137,276,564 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165657   ⟹   XP_036021550
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,243,263 - 137,250,700 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165658   ⟹   XP_036021551
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,243,263 - 137,250,692 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004942657
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,243,263 - 137,259,471 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: ENSMUSP00000136061   ⟸   ENSMUST00000179412
RefSeq Acc Id: ENSMUSP00000143027   ⟸   ENSMUST00000196391
RefSeq Acc Id: XP_036021549   ⟸   XM_036165656
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036021548   ⟸   XM_036165655
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036021547   ⟸   XM_036165654
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036021550   ⟸   XM_036165657
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036021551   ⟸   XM_036165658
- Peptide Label: isoform X5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3U5A2-F1-model_v2 AlphaFold Q3U5A2 1-218 view protein structure

Promoters
RGD ID:6888412
Promoter ID:EPDNEW_M7657
Type:initiation region
Name:AK153770_1
Description:n/a
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385137,210,845 - 137,210,905EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3588263 AgrOrtholog
Ensembl Genes ENSMUSG00000094840 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000179412.2 UniProtKB/TrEMBL
  ENSMUST00000196391.5 UniProtKB/TrEMBL
InterPro CSPG5 UniProtKB/TrEMBL
MGD MGI:3588263 ENTREZGENE
NCBI Gene 619309 ENTREZGENE
PANTHER CHONDROITIN SULFATE PROTEOGLYCAN 5 UniProtKB/TrEMBL
  CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED UniProtKB/TrEMBL
PhenoGen Muc3a PhenoGen
UniProt A0A0G2JF53_MOUSE UniProtKB/TrEMBL
  Q3U5A2_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-16 Muc3a  mucin 3A, cell surface associated  A630081J09Rik  RIKEN cDNA A630081J09 gene  Symbol and/or name change 5135510 APPROVED