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Gene: Nlrp1b (NLR family, pyrin domain containing 1B) Mus musculus
Analyze
Symbol:
Nlrp1b
Name:
NLR family, pyrin domain containing 1B
RGD ID:
1619488
MGI Page
MGI
Description:
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and nucleic acid binding activity. Acts upstream of or within protein catabolic process and pyroptosis. Predicted to be located in nucleoplasm. Predicted to be part of NLRP1 inflammasome complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1).
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
ENSMUSG00000070390; Na; NACHT, LRR and PYD domains-containing protein 1b; NACHT, LRR and PYD domains-containing protein 1b allele 2; NACHT-, LRR-, and PYD-containing protein 1 paralog b; Nalp1b; NLR family, pyrin domain containing 1B, CAST/EiJ specific, allele 3; NLR family, pyrin domain containing 1B, PWK/PhJ specific, allele 1; OTTMUSCASG00059402; OTTMUSPWKG00059388
RGD Orthologs
Alliance Genes
No known orthologs.
More Info
homologs ...
More Info
Latest Assembly:
GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 11 71,043,400 - 71,133,340 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 11 71,043,928 - 71,121,559 (-) Ensembl GRCm39 Ensembl GRCm38 11 71,152,574 - 71,242,514 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 11 71,153,102 - 71,230,733 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 11 70,966,604 - 71,044,235 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 11 70,966,604 - 71,044,235 (-) NCBI MGSCv36 mm8 Celera 11 78,667,725 - 78,767,716 (-) NCBI Celera Cytogenetic Map 11 B4 NCBI cM Map 11 43.23 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - KEGG (archival)
References
Additional References at PubMed
Genomics
QTLs in Region (GRCm39)
26884453 Sklq16_m skull length QTL 16, 16 week (mouse) 11 3250000 72690826 Mouse 13208559 Wght10_m weight 10 (mouse) 11 3950000 88890826 Mouse 13208558 Lgth12_m body length 12 (mouse) 11 3950000 94890826 Mouse 1300905 Scc6_m colon tumor susceptibility 6 (mouse) Not determined 11 6880277 89019734 Mouse 39128214 Lwq20_m liver weight QTL 20 (mouse) 11 12268637 118022724 Mouse 4141894 Nidd6k_m Nidd6 on KK-A (mouse) Not determined 19124204 96897826 Mouse 10412246 Dfs2_m dental fluorosis suseptibility 2 (mouse) Not determined 11 21807364 95881231 Mouse 13208569 Bmiq10_m body mass index QTL 10 (mouse) 11 35890827 84890826 Mouse 1301328 Mol4_m modifier of LPS-response 4 (mouse) Not determined 11 36282577 83481356 Mouse 4141853 Skmw17_m skeletal muscle weight 17 (mouse) Not determined 11 37080941 71081064 Mouse 10766457 Nwa3_m New Zealand White autoimmunity 3 (mouse) 11 38016115 72016209 Mouse 11532698 Sluc36a_m susceptibility to lung cancer 36a (mouse) 11 42256617 76256730 Mouse 11532699 Sluc36b_m susceptibility to lung cancer 36b (mouse) 11 42256617 76256730 Mouse 4142300 Ctrq3_m C. trachomatis resistance QTL 3 (mouse) Not determined 11 44630038 76854757 Mouse 4141367 Inf1_m acute ozone induced inflammation (mouse) Not determined 44630038 113058009 Mouse 1302021 Nidd1n_m non-insulin-dependent diabetes mellitus 1 in NSY (mouse) Not determined 11 45165873 79978324 Mouse 1357878 Mastr_m modifier of astrocytoma (mouse) Not determined 11 45708581 89818733 Mouse 1300765 Bbaa4_m B.burgdorferi-associated arthritis 4 (mouse) Not determined 11 46185167 80185262 Mouse 1301988 Bmd11_m bone mineral density 11 (mouse) Not determined 11 46319407 80319522 Mouse 1301830 Ssta4_m susceptibility to Salmonella typhimurium antigens 4 (mouse) Not determined 11 50078191 84078411 Mouse 13524840 Ppiq9a_m prepulse inhibition QTL 9a (mouse) 11 52494385 86494385 Mouse 1300774 Pgia7_m proteoglycan induced arthritis 7 (mouse) Not determined 11 53390588 87390737 Mouse 4141830 Pregq1_m pregnancy QTL 1 (mouse) Not determined 11 54126752 83733652 Mouse 4141875 Etax9_m ethanol induced ataxia 9 (mouse) Not determined 55284985 72209927 Mouse 4142121 Tmc1m2_m Tmc1 modifier 2 (mouse) Not determined 11 56864027 114157957 Mouse 1300664 Etohcta9_m ethanol conditioned taste aversion 9 (mouse) Not determined 11 57754660 91754758 Mouse 10053682 Eae45_m experimental allergic encephalomyelitis susceptibility 45 (mouse) Not determined 11 58490555 74754758 Mouse 1300924 Ity2_m immunity to S. typhimurium 2 (mouse) Not determined 1 58508030 87695238 Mouse 4141982 Skts-fp2_m skin tumor susceptibility in FVB and PWK 2 (mouse) Not determined 58719266 85066529 Mouse 1301987 Pid3_m prior incubation determinant 3 (mouse) Not determined 11 61686820 88699728 Mouse 1301319 Dautb4_m dopamine uptake transporter binding 4 (mouse) Not determined 11 62156005 96156153 Mouse 27226730 Tibmd1_m tibia midshaft diameter 1, 5 week (mouse) 11 62590826 109390826 Mouse 1301999 Lmr15_m leishmaniasis resistance 15 (mouse) Not determined 11 63319407 81830473 Mouse 10044004 Stzid3_m streptozotocin induced diabetes susceptibility 3 (mouse) Not determined 11 63319407 94063918 Mouse 11039502 Ltpr6b_m Leishmania tropica response 6b (mouse) 11 64830336 98830473 Mouse 11039501 Ltpr6a_m Leishmania tropica response 6a (mouse) 11 64830336 98830473 Mouse 11039515 Ltpr6_m Leishmania tropica response 6 (mouse) 11 64830336 98830473 Mouse 1357766 Si5lq6_m serum IGFBP-5 level QTL 6 (mouse) Not determined 11 66733420 100733652 Mouse 1301546 Pcir2_m periosteal circumference 2 (mouse) Not determined 11 66733420 100733652 Mouse 1301833 Tbbmd5_m total body bone mineral density 5 (mouse) Not determined 11 66733420 100733652 Mouse 1300628 Lgth6_m body length 6 (mouse) Not determined 11 66733420 100733652 Mouse 4141012 Femwf6_m femur work to failure 6 (mouse) Not determined 66733420 100733652 Mouse 1300784 Prdt3_m prion disease incubation time 3 (mouse) Not determined 11 66733420 100733652 Mouse 4142316 Ity2b_m immunity to S. typhimurium 2b (mouse) Not determined 11 67078191 79813912 Mouse 27226783 Tibl5_m tibia length 5, 5 week (mouse) 11 68190826 101890826 Mouse 36049778 Ars6_m antibody response to SARS-CoV 6, day 15, IgM (mouse) 11 68990826 72490826 Mouse 36049779 Ars7_m antibody response to SARS-CoV 7, day 29, IgG1 (mouse) 11 68990826 72490826 Mouse 36049784 Ars8_m antibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse) 11 68990826 72490826 Mouse 36049785 Ars9_m antibody response to SARS-CoV 9, day 29, IgM (mouse) 11 68990826 72490826 Mouse 36049786 Ars10_m antibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse) 11 68990826 72490826 Mouse 36049787 Ars11_m antibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse) 11 68990826 72490826 Mouse 36049788 Ars1_m antibody response to SARS-CoV 1, day 7, IgG1 (mouse) 11 68990826 72490826 Mouse 36049789 Ars2_m antibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse) 11 68990826 72490826 Mouse 36049790 Ars3_m antibody response to SARS-CoV 3, day 7, IgG2b (mouse) 11 68990826 72490826 Mouse 36049791 Ars4_m antibody response to SARS-CoV 4, day 7, IgG3 (mouse) 11 68990826 72490826 Mouse 36049792 Ars5_m antibody response to SARS-CoV 5, day 7, IgM (mouse) 11 68990826 72490826 Mouse 35673314 Ari2_m antibody response to influenza 2, day 10, IgG3 (mouse) 11 68990826 72490826 Mouse 1558812 Rafar_m retinoic acid induced forelimb autopod reduction (mouse) Not determined 11 70691198 104691366 Mouse 1301681 Sle13_m systematic lupus erythematosus susceptibility 13 (mouse) Not determined 11 70691198 104691366 Mouse 1300651 Pcyts3_m plasmacytoma susceptibility 3 (mouse) Not determined 11 70691198 104691366 Mouse 4141339 Nilac2_m nicotine induced locomotor activity 2 (mouse) Not determined 11 70691198 104691366 Mouse