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Gene: H2-DMb1 (histocompatibility 2, class II, locus Mb1) Mus musculus
Symbol: H2-DMb1
Name: histocompatibility 2, class II, locus Mb1
Description: Predicted to have MHC class II protein complex binding activity. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class II and chaperone cofactor-dependent protein refolding. Predicted to localize to MHC class II protein complex and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human HLA-DMB (major histocompatibility complex, class II, DM beta); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI385589; class II histocompatibility antigen, M beta 1 chain; H-2Mb1; H2-M beta 1 chain; H2-M beta1; H2-Mb1; MHC class II antigen Mb1
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1734,153,072 - 34,160,230 (+)EnsemblGRCm38mm10GRCm38
GRCm381734,153,191 - 34,160,229 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371734,290,136 - 34,297,174 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,755,892 - 33,762,211 (+)NCBImm8
Celera1735,203,417 - 35,204,017 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on H2-DMb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1619257
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.