Rtkn (rhotekin) - Rat Genome Database

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Gene: Rtkn (rhotekin) Mus musculus
Analyze
Symbol: Rtkn
Name: rhotekin
RGD ID: 1619247
MGI Page MGI
Description: Enables GTPase inhibitor activity and small GTPase binding activity. Predicted to be involved in several processes, including Rho protein signal transduction; cytoskeleton-dependent cytokinesis; and septin ring organization. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol. Predicted to be active in actomyosin contractile ring. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human RTKN (rhotekin).
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,112,485 - 83,129,560 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,112,444 - 83,129,560 (+)EnsemblGRCm39 Ensembl
GRCm38683,135,505 - 83,152,579 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,135,463 - 83,152,579 (+)EnsemblGRCm38mm10GRCm38
MGSCv37683,085,802 - 83,102,573 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,102,747 - 83,118,234 (+)NCBIMGSCv36mm8
Celera685,118,785 - 85,135,485 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma. Zhou J, etal., Oncol Rep. 2017 Feb;37(2):1227-1234. doi: 10.3892/or.2016.5290. Epub 2016 Dec 5.
Additional References at PubMed
PMID:8662891   PMID:9073523   PMID:9806835   PMID:10349636   PMID:10873388   PMID:10940294   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12015964   PMID:12466851   PMID:12477932  
PMID:12529446   PMID:12874278   PMID:12944407   PMID:14966563   PMID:15489334   PMID:15652341   PMID:15664190   PMID:15694321   PMID:15761153   PMID:15782199   PMID:15797222   PMID:15996550  
PMID:16141072   PMID:16141073   PMID:17331196   PMID:18448676   PMID:20300064   PMID:20348415   PMID:21029865   PMID:21873635   PMID:22404908   PMID:22503686   PMID:26410627   PMID:32325033  


Genomics

Comparative Map Data
Rtkn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,112,485 - 83,129,560 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,112,444 - 83,129,560 (+)EnsemblGRCm39 Ensembl
GRCm38683,135,505 - 83,152,579 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,135,463 - 83,152,579 (+)EnsemblGRCm38mm10GRCm38
MGSCv37683,085,802 - 83,102,573 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,102,747 - 83,118,234 (+)NCBIMGSCv36mm8
Celera685,118,785 - 85,135,485 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
RTKN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38274,425,835 - 74,441,937 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl274,425,835 - 74,442,422 (-)EnsemblGRCh38hg38GRCh38
GRCh37274,652,962 - 74,669,064 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,506,496 - 74,522,568 (-)NCBINCBI36Build 36hg18NCBI36
Build 34274,564,665 - 74,578,602NCBI
Celera274,484,177 - 74,500,249 (-)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef274,389,300 - 74,405,372 (-)NCBIHuRef
CHM1_1274,582,406 - 74,598,477 (-)NCBICHM1_1
T2T-CHM13v2.0274,434,392 - 74,450,497 (-)NCBIT2T-CHM13v2.0
Rtkn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,198,496 - 117,215,660 (+)NCBIGRCr8
mRatBN7.24115,640,813 - 115,657,952 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4115,640,774 - 115,657,952 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,118,990 - 121,134,644 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04116,894,175 - 116,909,827 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,508,440 - 115,524,100 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04114,833,453 - 114,850,705 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4114,835,064 - 114,850,701 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4113,968,995 - 113,984,632 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04179,422,348 - 179,439,775 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,348,330 - 117,363,967 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14117,592,810 - 117,608,448 (+)NCBI
Celera4104,636,452 - 104,652,089 (+)NCBICelera
Cytogenetic Map4q34NCBI
Rtkn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,344,220 - 11,360,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,344,504 - 11,358,344 (+)NCBIChiLan1.0ChiLan1.0
RTKN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21251,946,823 - 51,963,372 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A51,949,795 - 51,966,125 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A74,492,520 - 74,509,037 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A75,998,513 - 76,015,046 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A75,998,494 - 76,015,046 (-)Ensemblpanpan1.1panPan2
RTKN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11748,684,794 - 48,700,309 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1748,685,089 - 48,699,966 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,326,399 - 48,341,970 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01749,544,030 - 49,559,627 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1749,544,267 - 49,559,627 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11748,561,122 - 48,576,674 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01748,627,658 - 48,643,209 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,185,611 - 49,201,210 (+)NCBIUU_Cfam_GSD_1.0
Rtkn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629210,072,595 - 10,087,596 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936556650,303 - 665,324 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936556650,303 - 665,324 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RTKN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl368,598,249 - 68,613,631 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1368,598,560 - 68,613,633 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2371,811,931 - 71,823,550 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RTKN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,835,660 - 32,851,799 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1432,837,546 - 32,855,912 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604579,318,571 - 79,334,693 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rtkn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474929,060,934 - 29,076,451 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474929,061,202 - 29,077,928 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rtkn
424 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2000
Count of miRNA genes:613
Interacting mature miRNAs:738
Transcripts:ENSMUST00000065512, ENSMUST00000087938, ENSMUST00000121093, ENSMUST00000129316, ENSMUST00000130622, ENSMUST00000133226, ENSMUST00000135490
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse
15039373Adip28_madiposity 28 (mouse)65628519490285194Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65628519490285194Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65842456692424693Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65851741692517416Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66003466394034782Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666690851100691013Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670402880104403016Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670402880104403016Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670402880104403016Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7129960586252701Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67129960593441074Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671552042105552160Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671958006105958152Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671958006105958152Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
12792979Fbmd2_mfemoral bone mineral density 2, females only (mouse)675026989115026943Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675424566104480516Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67552133992584431Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67552133994202936Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67552133994202936Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675584287109584431Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675693484109693678Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676440930110441074Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67707698389976982Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67797698396976961Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678606487121092347Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681476981102176961Mouse

Markers in Region
U54638  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,152,444 - 83,152,526UniSTSGRCm38
MGSCv37683,102,438 - 83,102,520UniSTSGRCm37
Celera685,135,350 - 85,135,432UniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map6D1UniSTS
cM Map634.81UniSTS
Whitehead/MRC_RH6851.62UniSTS
D6UmiJ11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,136,476 - 83,136,645UniSTSGRCm38
MGSCv37683,086,470 - 83,086,639UniSTSGRCm37
Celera685,119,453 - 85,119,596UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.78UniSTS
D6UmiJ9  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,134,643 - 83,134,799UniSTSGRCm38
MGSCv37683,084,637 - 83,084,793UniSTSGRCm37
Celera685,117,620 - 85,117,776UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.77UniSTS
Rtkn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,152,382 - 83,152,555UniSTSGRCm38
MGSCv37683,102,376 - 83,102,549UniSTSGRCm37
Celera685,135,288 - 85,135,461UniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map6D1UniSTS
cM Map634.81UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001136227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_133641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC007306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC104324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB864269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG228325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ886086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY104108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY231175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX218519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U54638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000065512   ⟹   ENSMUSP00000065571
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,112,793 - 83,129,560 (+)Ensembl
GRCm38.p6 Ensembl683,135,812 - 83,152,579 (+)Ensembl
RefSeq Acc Id: ENSMUST00000087938   ⟹   ENSMUSP00000085249
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,114,091 - 83,129,560 (+)Ensembl
GRCm38.p6 Ensembl683,137,110 - 83,152,579 (+)Ensembl
RefSeq Acc Id: ENSMUST00000121093   ⟹   ENSMUSP00000112501
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,114,070 - 83,129,560 (+)Ensembl
GRCm38.p6 Ensembl683,137,089 - 83,152,579 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129316   ⟹   ENSMUSP00000120640
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,119,545 - 83,124,656 (+)Ensembl
GRCm38.p6 Ensembl683,142,564 - 83,147,675 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130622   ⟹   ENSMUSP00000122660
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,119,373 - 83,125,135 (+)Ensembl
GRCm38.p6 Ensembl683,142,392 - 83,148,154 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133226
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,127,736 - 83,129,189 (+)Ensembl
GRCm38.p6 Ensembl683,150,755 - 83,152,208 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135490   ⟹   ENSMUSP00000116964
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,112,444 - 83,126,539 (+)Ensembl
GRCm38.p6 Ensembl683,135,463 - 83,149,558 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203183
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,124,816 - 83,127,221 (+)Ensembl
GRCm38.p6 Ensembl683,147,835 - 83,150,240 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213056   ⟹   ENSMUSP00000148398
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl683,128,291 - 83,129,256 (+)Ensembl
GRCm38.p6 Ensembl683,151,310 - 83,152,275 (+)Ensembl
RefSeq Acc Id: NM_001136227   ⟹   NP_001129699
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,112,831 - 83,129,560 (+)NCBI
GRCm38683,135,808 - 83,152,579 (+)NCBI
MGSCv37683,085,802 - 83,102,573 (+)RGD
Celera685,118,785 - 85,135,485 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001355524   ⟹   NP_001342453
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,119,374 - 83,129,560 (+)NCBI
GRCm38683,142,106 - 83,152,579 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001355525   ⟹   NP_001342454
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,119,374 - 83,129,560 (+)NCBI
GRCm38683,142,106 - 83,152,579 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001410312   ⟹   NP_001397241
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,114,028 - 83,129,560 (+)NCBI
RefSeq Acc Id: NM_001410313   ⟹   NP_001397242
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,119,374 - 83,129,560 (+)NCBI
RefSeq Acc Id: NM_001410314   ⟹   NP_001397243
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,112,831 - 83,129,560 (+)NCBI
RefSeq Acc Id: NM_001410315   ⟹   NP_001397244
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,114,028 - 83,129,560 (+)NCBI
RefSeq Acc Id: NM_001410316   ⟹   NP_001397245
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,119,374 - 83,129,560 (+)NCBI
RefSeq Acc Id: NM_009106   ⟹   NP_033132
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,114,028 - 83,129,560 (+)NCBI
GRCm38683,137,084 - 83,152,579 (+)NCBI
MGSCv37683,085,802 - 83,102,573 (+)RGD
Celera685,118,785 - 85,135,485 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_133641   ⟹   NP_598396
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,114,028 - 83,129,560 (+)NCBI
GRCm38683,137,084 - 83,152,579 (+)NCBI
MGSCv37683,085,802 - 83,102,573 (+)RGD
Celera685,118,785 - 85,135,485 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505805   ⟹   XP_006505868
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,118,929 - 83,127,882 (+)NCBI
GRCm38683,141,990 - 83,150,901 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505807   ⟹   XP_006505870
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,112,656 - 83,127,882 (+)NCBI
GRCm38683,135,667 - 83,150,901 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505808   ⟹   XP_006505871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,113,975 - 83,127,882 (+)NCBI
GRCm38683,136,127 - 83,150,901 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505809   ⟹   XP_006505872
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,113,975 - 83,127,882 (+)NCBI
GRCm38683,136,986 - 83,150,901 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505810   ⟹   XP_006505873
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,112,485 - 83,127,882 (+)NCBI
GRCm38683,135,505 - 83,150,901 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505811   ⟹   XP_006505874
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,113,975 - 83,127,882 (+)NCBI
GRCm38683,136,987 - 83,150,901 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505812   ⟹   XP_006505875
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,119,374 - 83,127,882 (+)NCBI
GRCm38683,142,569 - 83,150,901 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255274   ⟹   XP_030111134
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,113,990 - 83,129,560 (+)NCBI
GRCm38683,136,190 - 83,152,579 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001129699 (Get FASTA)   NCBI Sequence Viewer  
  NP_001342453 (Get FASTA)   NCBI Sequence Viewer  
  NP_001342454 (Get FASTA)   NCBI Sequence Viewer  
  NP_001397241 (Get FASTA)   NCBI Sequence Viewer  
  NP_001397242 (Get FASTA)   NCBI Sequence Viewer  
  NP_001397243 (Get FASTA)   NCBI Sequence Viewer  
  NP_001397244 (Get FASTA)   NCBI Sequence Viewer  
  NP_001397245 (Get FASTA)   NCBI Sequence Viewer  
  NP_033132 (Get FASTA)   NCBI Sequence Viewer  
  NP_598396 (Get FASTA)   NCBI Sequence Viewer  
  XP_006505868 (Get FASTA)   NCBI Sequence Viewer  
  XP_006505870 (Get FASTA)   NCBI Sequence Viewer  
  XP_006505871 (Get FASTA)   NCBI Sequence Viewer  
  XP_006505872 (Get FASTA)   NCBI Sequence Viewer  
  XP_006505873 (Get FASTA)   NCBI Sequence Viewer  
  XP_006505874 (Get FASTA)   NCBI Sequence Viewer  
  XP_006505875 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111134 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52605 (Get FASTA)   NCBI Sequence Viewer  
  AAH13820 (Get FASTA)   NCBI Sequence Viewer  
  BAC36222 (Get FASTA)   NCBI Sequence Viewer  
  EDK99067 (Get FASTA)   NCBI Sequence Viewer  
  EDK99068 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000065571
  ENSMUSP00000065571.5
  ENSMUSP00000085249
  ENSMUSP00000085249.5
  ENSMUSP00000112501
  ENSMUSP00000112501.2
  ENSMUSP00000116964.2
  ENSMUSP00000120640.2
  ENSMUSP00000122660.2
  ENSMUSP00000148398.2
GenBank Protein Q8C6B2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_033132   ⟸   NM_009106
- Peptide Label: isoform b
- UniProtKB: Q8C6B2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_598396   ⟸   NM_133641
- Peptide Label: isoform b
- UniProtKB: Q8C6B2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001129699   ⟸   NM_001136227
- Peptide Label: isoform a
- UniProtKB: Q61192 (UniProtKB/Swiss-Prot),   E9QM24 (UniProtKB/Swiss-Prot),   Q8VIG7 (UniProtKB/Swiss-Prot),   Q8C6B2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006505873   ⟸   XM_006505810
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006505870   ⟸   XM_006505807
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006505871   ⟸   XM_006505808
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006505872   ⟸   XM_006505809
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006505874   ⟸   XM_006505811
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006505868   ⟸   XM_006505805
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006505875   ⟸   XM_006505812
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_030111134   ⟸   XM_030255274
- Peptide Label: isoform X7
RefSeq Acc Id: NP_001342454   ⟸   NM_001355525
- Peptide Label: isoform d
RefSeq Acc Id: NP_001342453   ⟸   NM_001355524
- Peptide Label: isoform c
RefSeq Acc Id: ENSMUSP00000122660   ⟸   ENSMUST00000130622
RefSeq Acc Id: ENSMUSP00000065571   ⟸   ENSMUST00000065512
RefSeq Acc Id: ENSMUSP00000085249   ⟸   ENSMUST00000087938
RefSeq Acc Id: ENSMUSP00000116964   ⟸   ENSMUST00000135490
RefSeq Acc Id: ENSMUSP00000112501   ⟸   ENSMUST00000121093
RefSeq Acc Id: ENSMUSP00000148398   ⟸   ENSMUST00000213056
RefSeq Acc Id: ENSMUSP00000120640   ⟸   ENSMUST00000129316
RefSeq Acc Id: NP_001397243   ⟸   NM_001410314
- Peptide Label: isoform f
RefSeq Acc Id: NP_001397244   ⟸   NM_001410315
- Peptide Label: isoform g
RefSeq Acc Id: NP_001397241   ⟸   NM_001410312
- Peptide Label: isoform e
RefSeq Acc Id: NP_001397245   ⟸   NM_001410316
- Peptide Label: isoform h
RefSeq Acc Id: NP_001397242   ⟸   NM_001410313
- Peptide Label: isoform e
Protein Domains
PH   REM-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C6B2-F1-model_v2 AlphaFold Q8C6B2 1-564 view protein structure

Promoters
RGD ID:6839953
Promoter ID:MM_KWN:46580
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000066648,   OTTMUST00000066651
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36683,084,586 - 83,085,997 (+)MPROMDB
RGD ID:6839949
Promoter ID:MM_KWN:46581
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000121093,   OTTMUST00000066650
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36683,086,166 - 83,088,077 (+)MPROMDB
RGD ID:6839952
Promoter ID:MM_KWN:46582
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   ES_Cell,   Lung
Transcripts:OTTMUST00000066652,   OTTMUST00000066654
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36683,091,706 - 83,092,557 (+)MPROMDB
RGD ID:6839954
Promoter ID:MM_KWN:46583
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:OTTMUST00000066653
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36683,099,956 - 83,101,057 (+)MPROMDB
RGD ID:6890138
Promoter ID:EPDNEW_M8520
Type:multiple initiation site
Name:Rtkn_1
Description:Mus musculus rhotekin , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8521  EPDNEW_M8522  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38683,135,868 - 83,135,928EPDNEW
RGD ID:6890140
Promoter ID:EPDNEW_M8521
Type:multiple initiation site
Name:Rtkn_2
Description:Mus musculus rhotekin , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8520  EPDNEW_M8522  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38683,137,047 - 83,137,107EPDNEW
RGD ID:6890142
Promoter ID:EPDNEW_M8522
Type:initiation region
Name:Rtkn_3
Description:Mus musculus rhotekin , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8520  EPDNEW_M8521  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38683,137,860 - 83,137,920EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107371 AgrOrtholog
Ensembl Genes ENSMUSG00000034930 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000065512 ENTREZGENE
  ENSMUST00000065512.11 UniProtKB/Swiss-Prot
  ENSMUST00000087938 ENTREZGENE
  ENSMUST00000087938.11 UniProtKB/Swiss-Prot
  ENSMUST00000121093 ENTREZGENE
  ENSMUST00000121093.8 UniProtKB/Swiss-Prot
  ENSMUST00000129316.2 UniProtKB/TrEMBL
  ENSMUST00000130622.8 UniProtKB/TrEMBL
  ENSMUST00000135490.8 UniProtKB/TrEMBL
  ENSMUST00000213056.2 UniProtKB/TrEMBL
InterPro AHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HR1_rho-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot
KEGG Report mmu:20166 UniProtKB/Swiss-Prot
MGD MGI:107371 ENTREZGENE
NCBI Gene 20166 ENTREZGENE
PANTHER ANILLIN/RHOTEKIN RTKN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21538:SF19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Anillin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rtkn PhenoGen
PROSITE REM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Hr1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
UniProt A0A1D5RLJ9_MOUSE UniProtKB/TrEMBL
  D3YXC9_MOUSE UniProtKB/TrEMBL
  D3Z4N1_MOUSE UniProtKB/TrEMBL
  D3Z7S7_MOUSE UniProtKB/TrEMBL
  E9QM24 ENTREZGENE
  Q61192 ENTREZGENE
  Q8C6B2 ENTREZGENE
  Q8VIG7 ENTREZGENE
  RTKN_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary E9QM24 UniProtKB/Swiss-Prot
  Q61192 UniProtKB/Swiss-Prot
  Q8VIG7 UniProtKB/Swiss-Prot