Nkpd1 (NTPase, KAP family P-loop domain containing 1) - Rat Genome Database

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Gene: Nkpd1 (NTPase, KAP family P-loop domain containing 1) Mus musculus
Analyze
Symbol: Nkpd1
Name: NTPase, KAP family P-loop domain containing 1
RGD ID: 1619158
MGI Page MGI
Description: Predicted to be located in membrane. Orthologous to human NKPD1 (NTPase KAP family P-loop domain containing 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2310015G09Rik; NTPase KAP family P-loop domain-containing protein 1
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,251,404 - 19,258,982 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,251,763 - 19,258,981 (+)EnsemblGRCm39 Ensembl
GRCm38719,517,491 - 19,525,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,517,838 - 19,525,056 (+)EnsemblGRCm38mm10GRCm38
MGSCv37720,104,080 - 20,110,399 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,677,253 - 18,683,297 (+)NCBIMGSCv36mm8
Celera716,924,662 - 16,930,981 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15935074   PMID:16141072   PMID:16141073   PMID:21267068  


Genomics

Comparative Map Data
Nkpd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,251,404 - 19,258,982 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,251,763 - 19,258,981 (+)EnsemblGRCm39 Ensembl
GRCm38719,517,491 - 19,525,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,517,838 - 19,525,056 (+)EnsemblGRCm38mm10GRCm38
MGSCv37720,104,080 - 20,110,399 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,677,253 - 18,683,297 (+)NCBIMGSCv36mm8
Celera716,924,662 - 16,930,981 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.92NCBI
NKPD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,149,744 - 45,162,841 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,149,744 - 45,160,982 (-)EnsemblGRCh38hg38GRCh38
GRCh371945,653,002 - 45,664,240 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,347,001 - 50,348,950 (-)NCBINCBI36Build 36hg18NCBI36
Build 341950,346,782 - 50,348,869NCBI
Celera1942,457,268 - 42,467,668 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,083,153 - 42,093,553 (-)NCBIHuRef
CHM1_11945,656,299 - 45,666,699 (-)NCBICHM1_1
T2T-CHM13v2.01947,974,875 - 47,987,974 (-)NCBIT2T-CHM13v2.0
Nkpd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,293,626 - 88,303,117 (+)NCBIGRCr8
mRatBN7.2179,165,642 - 79,175,126 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,167,130 - 79,174,234 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0180,424,507 - 80,434,137 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,426,918 - 80,432,875 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,690,528 - 81,700,156 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,871,611 - 78,877,568 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera173,625,165 - 73,634,793 (+)NCBICelera
Cytogenetic Map1q21NCBI
NKPD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,308,253 - 51,322,174 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,179,741 - 53,193,600 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,096,345 - 42,110,023 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,702,300 - 50,711,311 (-)NCBIpanpan1.1PanPan1.1panPan2
NKPD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,341,639 - 110,349,415 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,341,502 - 110,349,127 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,820,189 - 109,831,308 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,868,594 - 110,879,720 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11110,544,170 - 110,555,282 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,178,819 - 110,189,933 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01111,048,010 - 111,059,144 (+)NCBIUU_Cfam_GSD_1.0
Nkpd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,337,557 - 17,345,094 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,684,824 - 1,688,383 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,685,113 - 1,691,897 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NKPD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,568,059 - 51,579,205 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,567,895 - 51,578,769 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NKPD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,606,570 - 38,617,068 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607318,197,186 - 18,209,585 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nkpd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249071,907,422 - 1,914,490 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249071,907,501 - 1,925,722 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nkpd1
184 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:113
Interacting mature miRNAs:126
Transcripts:ENSMUST00000078908
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000078908   ⟹   ENSMUSP00000077943
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl719,252,656 - 19,258,975 (+)Ensembl
GRCm38.p6 Ensembl719,518,731 - 19,525,050 (+)Ensembl
RefSeq Acc Id: ENSMUST00000207576   ⟹   ENSMUSP00000147092
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl719,251,763 - 19,258,981 (+)Ensembl
GRCm38.p6 Ensembl719,517,838 - 19,525,056 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214205   ⟹   ENSMUSP00000151162
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl719,252,656 - 19,258,981 (+)Ensembl
GRCm38.p6 Ensembl719,518,731 - 19,525,056 (+)Ensembl
RefSeq Acc Id: NM_001405941   ⟹   NP_001392870
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,251,551 - 19,258,982 (+)NCBI
RefSeq Acc Id: NM_027116   ⟹   NP_081392
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,251,551 - 19,258,982 (+)NCBI
GRCm38719,518,731 - 19,525,050 (+)NCBI
MGSCv37720,104,080 - 20,110,399 (+)RGD
Celera716,924,662 - 16,930,981 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006540350   ⟹   XP_006540413
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,251,404 - 19,258,982 (+)NCBI
GRCm38719,517,491 - 19,525,057 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242971   ⟹   XP_030098831
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,251,409 - 19,258,982 (+)NCBI
GRCm38719,517,495 - 19,525,057 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_081392   ⟸   NM_027116
- Peptide Label: isoform 1
- UniProtKB: H7BX48 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006540413   ⟸   XM_006540350
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030098831   ⟸   XM_030242971
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000147092   ⟸   ENSMUST00000207576
RefSeq Acc Id: ENSMUSP00000077943   ⟸   ENSMUST00000078908
RefSeq Acc Id: ENSMUSP00000151162   ⟸   ENSMUST00000214205
RefSeq Acc Id: NP_001392870   ⟸   NM_001405941
- Peptide Label: isoform 2
- UniProtKB: A0A1L1SVH6 (UniProtKB/TrEMBL)
Protein Domains
KAP NTPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q0VF94-F1-model_v2 AlphaFold Q0VF94 1-599 view protein structure

Promoters
RGD ID:6892098
Promoter ID:EPDNEW_M9500
Type:single initiation site
Name:Nkpd1_1
Description:Mus musculus NTPase, KAP family P-loop domain containing 1 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38719,518,715 - 19,518,775EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916797 AgrOrtholog
Ensembl Genes ENSMUSG00000060621 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078908.5 UniProtKB/TrEMBL
  ENSMUST00000207576 ENTREZGENE
  ENSMUST00000207576.2 UniProtKB/TrEMBL
  ENSMUST00000214205 ENTREZGENE
  ENSMUST00000214205.2 UniProtKB/TrEMBL
InterPro KAP_P-loop UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69547 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1916797 ENTREZGENE
NCBI Gene 69547 ENTREZGENE
PANTHER NTPASE KAP FAMILY P-LOOP DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NTPASE, KAP FAMILY P-LOOP DOMAIN-CONTAINING 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam KAP_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nkpd1 PhenoGen
UniProt A0A1L1SVH6 ENTREZGENE, UniProtKB/TrEMBL
  H7BX48 ENTREZGENE, UniProtKB/TrEMBL
  NKPD1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q9D7C6 UniProtKB/Swiss-Prot