Chst14 (carbohydrate sulfotransferase 14) - Rat Genome Database

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Gene: Chst14 (carbohydrate sulfotransferase 14) Mus musculus
Analyze
Symbol: Chst14
Name: carbohydrate sulfotransferase 14
RGD ID: 1619123
MGI Page MGI
Description: Predicted to have N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in dermatan sulfate biosynthetic process. Predicted to localize to Golgi apparatus and integral component of membrane. Is expressed in several structures, including brain; liver; and retina. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 1. Orthologous to human CHST14 (carbohydrate sulfotransferase 14); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2600016L03Rik; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; D4st; D4ST-; D4ST-1; D4st1; dermatan 4 sulfotransferase 1; dermatan 4-sulfotransferase 1; dermatan-4-sulfotransferase-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392118,756,978 - 118,759,066 (+)NCBIGRCm39mm39
GRCm39 Ensembl2118,756,977 - 118,759,066 (+)Ensembl
GRCm382118,926,497 - 118,928,585 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2118,926,496 - 118,928,585 (+)EnsemblGRCm38mm10GRCm38
MGSCv372118,752,233 - 118,754,321 (+)NCBIGRCm37mm9NCBIm37
MGSCv362118,617,965 - 118,620,026 (+)NCBImm8
Celera2120,078,074 - 120,080,162 (+)NCBICelera
Cytogenetic Map2E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11591653   PMID:12466851   PMID:12477932   PMID:14681479   PMID:15226823   PMID:15489334   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:18079434   PMID:18799693   PMID:18819920   PMID:20562862   PMID:21267068   PMID:21873635   PMID:22159417   PMID:23360803   PMID:26586562   PMID:29206923   PMID:30228991  
PMID:30853887  


Genomics

Comparative Map Data
Chst14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392118,756,978 - 118,759,066 (+)NCBIGRCm39mm39
GRCm39 Ensembl2118,756,977 - 118,759,066 (+)Ensembl
GRCm382118,926,497 - 118,928,585 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2118,926,496 - 118,928,585 (+)EnsemblGRCm38mm10GRCm38
MGSCv372118,752,233 - 118,754,321 (+)NCBIGRCm37mm9NCBIm37
MGSCv362118,617,965 - 118,620,026 (+)NCBImm8
Celera2120,078,074 - 120,080,162 (+)NCBICelera
Cytogenetic Map2E5NCBI
CHST14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1540,470,984 - 40,473,158 (+)EnsemblGRCh38hg38GRCh38
GRCh381540,470,984 - 40,473,158 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371540,763,183 - 40,765,357 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,550,505 - 38,552,646 (+)NCBINCBI36hg18NCBI36
Build 341538,550,504 - 38,552,645NCBI
Celera1517,529,304 - 17,531,501 (+)NCBI
Cytogenetic Map15q15.1NCBI
HuRef1517,607,018 - 17,609,215 (+)NCBIHuRef
CHM1_11540,883,323 - 40,885,520 (+)NCBICHM1_1
Chst14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23105,916,481 - 105,918,538 (+)NCBI
Rnor_6.0 Ensembl3110,734,105 - 110,736,162 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03110,734,105 - 110,736,162 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03117,272,042 - 117,274,099 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,439,600 - 105,441,657 (+)NCBIRGSC3.4rn4RGSC3.4
Celera3104,829,671 - 104,831,728 (+)NCBICelera
Cytogenetic Map3q35NCBI
Chst14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554167,391,282 - 7,392,355 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554167,391,281 - 7,393,137 (+)NCBIChiLan1.0ChiLan1.0
CHST14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11537,660,619 - 37,662,436 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1537,660,621 - 37,661,622 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01519,407,477 - 19,409,645 (+)NCBIMhudiblu_PPA_v0panPan3
CHST14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1307,640,988 - 7,643,576 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl307,640,637 - 7,642,778 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha307,695,395 - 7,697,327 (+)NCBI
ROS_Cfam_1.0307,767,476 - 7,769,408 (+)NCBI
UMICH_Zoey_3.1307,691,749 - 7,693,681 (+)NCBI
UNSW_CanFamBas_1.0307,797,791 - 7,799,723 (+)NCBI
UU_Cfam_GSD_1.0307,926,684 - 7,928,616 (+)NCBI
Chst14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864086,079,826 - 86,084,278 (+)NCBI
SpeTri2.0NW_0049364713,930,167 - 3,932,356 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHST14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11130,845,103 - 130,847,203 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21145,930,319 - 145,932,401 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHST14
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12642,538,380 - 42,540,588 (-)NCBI
ChlSab1.1 Ensembl2642,539,203 - 42,540,333 (-)Ensembl
Vero_WHO_p1.0NW_02366604898,429,750 - 98,431,975 (+)NCBI
Chst14
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248047,769,254 - 7,771,368 (+)NCBI

Position Markers
UniSTS:234495  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382118,927,824 - 118,928,189UniSTSGRCm38
MGSCv372118,753,560 - 118,753,925UniSTSGRCm37
Celera2120,079,401 - 120,079,766UniSTS
Cytogenetic Map2E5UniSTS
Chst14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382118,926,783 - 118,927,227UniSTSGRCm38
MGSCv372118,752,519 - 118,752,963UniSTSGRCm37
Celera2120,078,360 - 120,078,804UniSTS
Cytogenetic Map2E5UniSTS
cM Map2 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116235703150235821Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2111085773154512747Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245457623145470727Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111331784145331901Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118758772160769245Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115370937149371074Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103265371129371085Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112370826146371085Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88313078122313225Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114457594132872237Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286265371120265478Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287610298121610433Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220892967119064359Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116464410150464554Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102800000160100000Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220892967119064359Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111331784145331901Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286265371120265478Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297292889131293051Mouse
1300798Actre3_mactivity response to ethanol 3 (mouse)Not determined2112194642128331901Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100993579134993788Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115370937149371074Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118758772160769245Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297292889131293051Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220892967119064359Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292948120126948262Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107413756141413756Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229417935148533014Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111331784145331901Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220892967119064359Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2101112449135112609Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274693773129371085Mouse
1301415Actre4_mactivity response to ethanol 4 (mouse)Not determined2112194642128331901Mouse
12904007Cfq7_mconditioned fear QTL 7 (mouse)2118526291125206952Mouse
1558825Aabpr_maberrant activation of B cell proliferation (mouse)Not determined2116202748122377053Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294400000154400000Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110647738144647887Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2118112449174483070Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106391660140391809Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220892967119064359Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220892967119064359Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118758772160769245Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111331784145331901Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288184658122184825Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286265371120265478Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118758772160769245Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297379883131379883Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)262000000137000000Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286265371120265478Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284182854148825550Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291259629125259759Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260690268119525037Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297379883131379883Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285893925181254801Mouse
1357829Lvrq1_mliver weight QTL 1 (mouse)Not determined220892967119064359Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265439402162677006Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112370826146371085Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111781466145781606Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224334620148858457Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220892967119064359Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111709108145709243Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2101112449135112609Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2101112449135112609Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284182854148680255Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103265371167370436Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112370826146371085Mouse
13506762Tbvq2_mtrabecular bone volume QTL 2 (mouse)2115600000124900000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:643
Count of miRNA genes:249
Interacting mature miRNAs:289
Transcripts:ENSMUST00000099546, ENSMUST00000110837
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000099546   ⟹   ENSMUSP00000099579
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl2118,926,496 - 118,928,585 (+)Ensembl
RefSeq Acc Id: ENSMUST00000110837   ⟹   ENSMUSP00000106461
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl2118,926,514 - 118,928,579 (+)Ensembl
RefSeq Acc Id: NM_028117   ⟹   NP_082393
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392118,756,978 - 118,759,066 (+)NCBI
GRCm382118,926,497 - 118,928,585 (+)ENTREZGENE
MGSCv372118,752,233 - 118,754,321 (+)RGD
Celera2120,078,074 - 120,080,162 (+)RGD
cM Map2 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_082393   ⟸   NM_028117
- UniProtKB: Q80V53 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000106461   ⟸   ENSMUST00000110837
RefSeq Acc Id: ENSMUSP00000099579   ⟸   ENSMUST00000099546

Promoters
RGD ID:6831037
Promoter ID:MM_KWN:31203
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000110837,   NM_028117
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362118,751,596 - 118,752,462 (+)MPROMDB
RGD ID:6878318
Promoter ID:EPDNEW_M2610
Type:initiation region
Name:Chst14_1
Description:Mus musculus carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase14 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382118,926,530 - 118,926,590EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1919386 AgrOrtholog
Ensembl Genes ENSMUSG00000074916 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000099579 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000106461 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000099546 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000110837 UniProtKB/TrEMBL
InterPro Carb_sulfotrans_8-10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfotransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:72136 UniProtKB/Swiss-Prot
MGD MGI:1919386 ENTREZGENE
NCBI Gene 72136 ENTREZGENE
PANTHER PTHR12137 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sulfotransfer_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Chst14 PhenoGen
UniProt A2AQV2_MOUSE UniProtKB/TrEMBL
  CHSTE_MOUSE UniProtKB/Swiss-Prot
  Q3U2T1_MOUSE UniProtKB/TrEMBL
  Q3U3W1_MOUSE UniProtKB/TrEMBL
  Q80V53 ENTREZGENE
UniProt Secondary A2AQV3 UniProtKB/Swiss-Prot
  Q3TXA1 UniProtKB/Swiss-Prot
  Q8R304 UniProtKB/Swiss-Prot
  Q9D0P2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-10-09 Chst14  carbohydrate sulfotransferase 14    carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14  Symbol and/or name change 5135510 APPROVED