Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pcgf5 | Mouse | (+)-schisandrin B | multiple interactions | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PCGF5 mRNA] | CTD | PMID:31150632 | Pcgf5 | Mouse | (-)-demecolcine | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of PCGF5 mRNA | CTD | PMID:23649840 | Pcgf5 | Mouse | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of PCGF5 mRNA | CTD | PMID:28960355 | Pcgf5 | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PCGF5 mRNA | CTD | PMID:22206623 | Pcgf5 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PCGF5 mRNA | CTD | PMID:21215274 | Pcgf5 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PCGF5 mRNA | CTD | PMID:21570461 | Pcgf5 | Mouse | 4,4'-sulfonyldiphenol | increases methylation | ISO | PCGF5 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of PCGF5 gene | CTD | PMID:31601247 | Pcgf5 | Mouse | 4-hydroxynon-2-enal | decreases expression | EXP | | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of PCGF5 mRNA | CTD | PMID:19191707 | Pcgf5 | Mouse | 6-propyl-2-thiouracil | decreases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of PCGF5 mRNA | CTD | PMID:24780913 | Pcgf5 | Mouse | all-trans-retinoic acid | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PCGF5 mRNA | CTD | PMID:33167477 | Pcgf5 | Mouse | antirheumatic drug | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of PCGF5 mRNA | CTD | PMID:24449571 | Pcgf5 | Mouse | aristolochic acid A | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PCGF5 mRNA | CTD | PMID:33212167 | Pcgf5 | Mouse | Aroclor 1254 | decreases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of PCGF5 mRNA | CTD | PMID:23650126 | Pcgf5 | Mouse | atrazine | affects methylation | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of PCGF5 gene | CTD | PMID:35440735 | Pcgf5 | Mouse | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PCGF5 mRNA | CTD | PMID:22228805 | Pcgf5 | Mouse | benzo[a]pyrene | increases methylation | ISO | PCGF5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PCGF5 promoter | CTD | PMID:27901495 | Pcgf5 | Mouse | benzo[a]pyrene diol epoxide I | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Pcgf5 | Mouse | beta-lapachone | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of PCGF5 mRNA | CTD | PMID:38218311 | Pcgf5 | Mouse | bis(2-ethylhexyl) phthalate | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of PCGF5 mRNA | CTD | PMID:31163220 | Pcgf5 | Mouse | bisphenol A | increases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PCGF5 mRNA | CTD | PMID:25181051 | Pcgf5 | Mouse | bisphenol A | affects expression | ISO | PCGF5 (Homo sapiens) | 6480464 | bisphenol A affects the expression of PCGF5 mRNA | CTD | PMID:30903817 | Pcgf5 | Mouse | bisphenol A | decreases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PCGF5 mRNA | CTD | PMID:30816183 | Pcgf5 | Mouse | butanal | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of PCGF5 mRNA | CTD | PMID:26079696 | Pcgf5 | Mouse | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon results in increased expression of PCGF5 mRNA | CTD | PMID:25554681 | Pcgf5 | Mouse | CGP 52608 | multiple interactions | ISO | PCGF5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PCGF5 gene] | CTD | PMID:28238834 | Pcgf5 | Mouse | copper(II) sulfate | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of PCGF5 mRNA | CTD | PMID:19549813 | Pcgf5 | Mouse | dorsomorphin | multiple interactions | ISO | PCGF5 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Pcgf5 | Mouse | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of PCGF5 mRNA | CTD | PMID:25896364 | Pcgf5 | Mouse | doxorubicin | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PCGF5 mRNA | CTD | PMID:29803840 | Pcgf5 | Mouse | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of PCGF5 mRNA | CTD | PMID:35436446 | Pcgf5 | Mouse | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of PCGF5 mRNA | CTD | PMID:25629700 | Pcgf5 | Mouse | formaldehyde | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of PCGF5 mRNA | CTD | PMID:23649840 | Pcgf5 | Mouse | genistein | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Genistein results in decreased expression of PCGF5 mRNA | CTD | PMID:25136773 | Pcgf5 | Mouse | gentamycin | increases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of PCGF5 mRNA | CTD | PMID:33387578 | Pcgf5 | Mouse | gold atom | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Gold results in decreased expression of PCGF5 mRNA | CTD | PMID:25523186 | Pcgf5 | Mouse | gold(0) | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Gold results in decreased expression of PCGF5 mRNA | CTD | PMID:25523186 | Pcgf5 | Mouse | iron atom | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Iron deficiency results in increased expression of PCGF5 mRNA | CTD | PMID:20368581 | Pcgf5 | Mouse | iron(0) | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Iron deficiency results in increased expression of PCGF5 mRNA | CTD | PMID:20368581 | Pcgf5 | Mouse | lipopolysaccharide | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of PCGF5 mRNA | CTD | PMID:35811015 | Pcgf5 | Mouse | lipopolysaccharide | multiple interactions | ISO | PCGF5 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PCGF5 mRNA | CTD | PMID:35811015 | Pcgf5 | Mouse | methylmercury chloride | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of PCGF5 mRNA | CTD | PMID:28001369 | Pcgf5 | Mouse | nickel atom | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Nickel results in increased expression of PCGF5 mRNA | CTD | PMID:25583101 | Pcgf5 | Mouse | nickel dichloride | affects expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | nickel chloride affects the expression of PCGF5 mRNA | CTD | PMID:22110744 | Pcgf5 | Mouse | nickel sulfate | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of PCGF5 mRNA | CTD | PMID:22714537 | Pcgf5 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of PCGF5 mRNA | CTD | PMID:17562736 | Pcgf5 | Mouse | paracetamol | increases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of PCGF5 mRNA | CTD | PMID:33387578 | Pcgf5 | Mouse | perfluorohexanesulfonic acid | decreases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in decreased expression of PCGF5 mRNA | CTD | PMID:37995155 | Pcgf5 | Mouse | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of PCGF5 mRNA | CTD | PMID:23091169 | Pcgf5 | Mouse | phenylmercury acetate | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of PCGF5 mRNA | CTD | PMID:26272509 | Pcgf5 | Mouse | phenylmercury acetate | multiple interactions | ISO | PCGF5 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PCGF5 mRNA | CTD | PMID:27188386 | Pcgf5 | Mouse | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PCGF5 mRNA | CTD | PMID:19710929 | Pcgf5 | Mouse | propanal | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | propionaldehyde results in decreased expression of PCGF5 mRNA | CTD | PMID:26079696 | Pcgf5 | Mouse | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | PCGF5 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PCGF5 mRNA | CTD | PMID:35811015 | Pcgf5 | Mouse | SB 431542 | multiple interactions | ISO | PCGF5 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Pcgf5 | Mouse | sodium arsenite | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PCGF5 mRNA | CTD | PMID:38568856 | Pcgf5 | Mouse | succimer | multiple interactions | ISO | PCGF5 (Homo sapiens) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of PCGF5 mRNA | CTD | PMID:26378955 | Pcgf5 | Mouse | sunitinib | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PCGF5 mRNA | CTD | PMID:31533062 | Pcgf5 | Mouse | tetrachloromethane | increases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of PCGF5 mRNA | CTD | PMID:31150632 | Pcgf5 | Mouse | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of PCGF5 mRNA | CTD | PMID:31919559 | Pcgf5 | Mouse | tetrachloromethane | multiple interactions | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PCGF5 mRNA] | CTD | PMID:31150632 | Pcgf5 | Mouse | thioacetamide | increases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of PCGF5 mRNA | CTD | PMID:34492290 | Pcgf5 | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of PCGF5 gene | CTD | PMID:35295148 | Pcgf5 | Mouse | trichostatin A | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PCGF5 mRNA | CTD | PMID:24935251 | Pcgf5 | Mouse | triclosan | decreases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of PCGF5 mRNA | CTD | PMID:30510588 | Pcgf5 | Mouse | triphenyl phosphate | increases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of PCGF5 mRNA | CTD | PMID:30589522 | Pcgf5 | Mouse | triphenyl phosphate | affects expression | ISO | PCGF5 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PCGF5 mRNA | CTD | PMID:37042841 | Pcgf5 | Mouse | valproic acid | increases methylation | ISO | PCGF5 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of PCGF5 gene | CTD | PMID:29154799 | Pcgf5 | Mouse | valproic acid | multiple interactions | ISO | PCGF5 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PCGF5 mRNA | CTD | PMID:27188386 | Pcgf5 | Mouse | valproic acid | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PCGF5 mRNA | CTD | PMID:23179753 more ... | Pcgf5 | Mouse | valproic acid | affects expression | ISO | PCGF5 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PCGF5 mRNA | CTD | PMID:25979313 | Pcgf5 | Mouse | vinclozolin | affects expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | vinclozolin affects the expression of PCGF5 mRNA | CTD | PMID:19015723 | Pcgf5 | Mouse | vinclozolin | decreases expression | ISO | Pcgf5 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of PCGF5 mRNA | CTD | PMID:23034163 | Pcgf5 | Mouse | vorinostat | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | vorinostat results in increased expression of PCGF5 mRNA | CTD | PMID:27188386 | Pcgf5 | Mouse | zoledronic acid | increases expression | ISO | PCGF5 (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of PCGF5 mRNA | CTD | PMID:20977926 | |