Nutm2 (NUT family member 2) - Rat Genome Database

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Gene: Nutm2 (NUT family member 2) Mus musculus
Analyze
Symbol: Nutm2
Name: NUT family member 2
RGD ID: 1618793
MGI Page MGI
Description: Orthologous to several human genes including NUTM2A (NUT family member 2A) and NUTM2B (NUT family member 2B).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fam22; Gm806; hypothetical protein LOC328250; NUT family member Gm806
RGD Orthologs
Human
Bonobo
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391350,621,343 - 50,629,391 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1350,621,343 - 50,629,391 (+)EnsemblGRCm39 Ensembl
GRCm381350,467,307 - 50,475,355 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1350,467,307 - 50,475,355 (+)EnsemblGRCm38mm10GRCm38
MGSCv371350,562,676 - 50,570,724 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361350,479,804 - 50,487,852 (+)NCBIMGSCv36mm8
Celera1351,554,147 - 51,562,195 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1325.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21677750   PMID:27626380   PMID:30973865  


Genomics

Comparative Map Data
Nutm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391350,621,343 - 50,629,391 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1350,621,343 - 50,629,391 (+)EnsemblGRCm39 Ensembl
GRCm381350,467,307 - 50,475,355 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1350,467,307 - 50,475,355 (+)EnsemblGRCm38mm10GRCm38
MGSCv371350,562,676 - 50,570,724 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361350,479,804 - 50,487,852 (+)NCBIMGSCv36mm8
Celera1351,554,147 - 51,562,195 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1325.75NCBI
NUTM2G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38996,928,843 - 96,942,971 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl996,928,310 - 96,940,253 (+)EnsemblGRCh38hg38GRCh38
GRCh37999,691,125 - 99,705,253 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,730,413 - 98,744,393 (+)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map9q22.33NCBI
CHM1_1999,838,303 - 99,851,567 (+)NCBICHM1_1
T2T-CHM13v2.09109,100,632 - 109,114,736 (+)NCBIT2T-CHM13v2.0
LOC117981758
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21145,118,423 - 45,132,963 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1945,119,171 - 45,136,406 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0968,021,404 - 68,032,256 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC119870860
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ROS_Cfam_1.0198,329,774 - 98,334,945 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1197,954,191 - 97,961,392 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0197,675,541 - 97,679,987 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0198,472,786 - 98,481,155 (-)NCBIUU_Cfam_GSD_1.0
LOC100514433
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.215155,456,994 - 155,464,476 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Nutm2
181 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:133
Count of miRNA genes:127
Interacting mature miRNAs:131
Transcripts:ENSMUST00000096633
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1558898Hpi1_mhapatic PMN infiltration 1 (mouse)Not determined13441402553101640Mouse
1301880Hypt_mhypertension (mouse)Not determined131815679252156924Mouse
13463469Gssq1_mglomerulosclerosis severity QTL 1 (mouse)131906090853061050Mouse
12880423V25Dq7_mvitamin D inactive form serum level QTL 7 (mouse)131958398353583983Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132047761259821605Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
1357591Tesq1_mtestis weight QTL 1 (mouse)Not determined132061551255720517Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
10045618Heal17_mwound healing/regeneration 17 (mouse)Not determined132074693954747056Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2583652959836529Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132791846961918560Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132821044262210544Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132821737962217515Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132821737962217515Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
12738427Lfibq24_mliver fibrosis QTL 24 (mouse)134425810752758667Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000096633   ⟹   ENSMUSP00000094390
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1350,621,343 - 50,629,391 (+)Ensembl
GRCm38.p6 Ensembl1350,467,307 - 50,475,355 (+)Ensembl
RefSeq Acc Id: NM_001033400   ⟹   NP_001028572
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391350,621,343 - 50,629,391 (+)NCBI
GRCm381350,467,307 - 50,475,355 (+)ENTREZGENE
MGSCv371350,562,676 - 50,570,724 (+)RGD
Celera1351,554,147 - 51,562,195 (+)RGD
cM Map13 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001028572 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAE21581 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000094390
  ENSMUSP00000094390.3
GenBank Protein Q3V0C3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001028572   ⟸   NM_001033400
- UniProtKB: Q3V0C3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000094390   ⟸   ENSMUST00000096633

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3V0C3-F1-model_v2 AlphaFold Q3V0C3 1-733 view protein structure

Promoters
RGD ID:8680326
Promoter ID:EPDNEW_M18194
Type:single initiation site
Name:Nutm2_1
Description:Mus musculus NUT family member 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381350,467,307 - 50,467,367EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685652 AgrOrtholog
Ensembl Genes ENSMUSG00000071909 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000096633 ENTREZGENE
  ENSMUST00000096633.3 UniProtKB/Swiss-Prot
InterPro NUT UniProtKB/Swiss-Prot
  NUT_N UniProtKB/Swiss-Prot
KEGG Report mmu:328250 UniProtKB/Swiss-Prot
MGD MGI:2685652 ENTREZGENE
NCBI Gene 328250 ENTREZGENE
PANTHER NUT FAMILY MEMBER 2A-RELATED UniProtKB/Swiss-Prot
  PTHR22879 UniProtKB/Swiss-Prot
Pfam NUT UniProtKB/Swiss-Prot
PhenoGen Nutm2 PhenoGen
UniProt NUTM2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-12-30 Nutm2  NUT family member 2  Gm806  predicted gene 806  Symbol and/or name change 5135510 APPROVED