H2al1o (H2A histone family member L1O) - Rat Genome Database

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Pathways
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Gene: H2al1o (H2A histone family member L1O) Mus musculus
Analyze
No known orthologs.
Symbol: H2al1o
Name: H2A histone family member L1O
RGD ID: 1618772
MGI Page MGI
Description: Predicted to enable nucleosomal DNA binding activity. Predicted to be involved in heterochromatin organization. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to human H2AL3 (H2A.L variant histone 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG333452; Gm5132; hypothetical protein LOC333452; Novel protein similar to histone H2a; predicted gene 5132; uncharacterized protein LOC333452
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X9,438,199 - 9,438,630 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX9,438,140 - 9,438,648 (-)EnsemblGRCm39 Ensembl
GRCm38X9,571,960 - 9,572,391 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX9,571,901 - 9,572,409 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X9,149,086 - 9,149,517 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X8,728,975 - 8,729,307 (-)NCBIMGSCv36mm8
CeleraX7,295,548 - 7,295,979 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX4.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleosome  (IBA)
nucleus  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
Additional References at PubMed
PMID:21873635  


Genomics

Variants

.
Variants in H2al1o
12 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:203
Count of miRNA genes:198
Interacting mature miRNAs:203
Transcripts:ENSMUST00000079952, ENSMUST00000105137
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302195Pbwg10_mpostnatal body weight growth 10 (mouse)Not determinedX126202173Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001085517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL671118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000079952   ⟹   ENSMUSP00000078870
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX9,438,140 - 9,438,648 (-)Ensembl
GRCm38.p6 EnsemblX9,571,901 - 9,572,409 (-)Ensembl
RefSeq Acc Id: NM_001085517   ⟹   NP_001078986
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X9,438,199 - 9,438,630 (-)NCBI
GRCm38X9,571,960 - 9,572,391 (-)ENTREZGENE
MGSCv37X9,149,086 - 9,149,517 (-)RGD
CeleraX7,295,548 - 7,295,979 (-)RGD
cM MapX ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001078986 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000078870
  ENSMUSP00000078870.4
Reference Protein Sequences
RefSeq Acc Id: NP_001078986   ⟸   NM_001085517
- UniProtKB: L7MU04 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000078870   ⟸   ENSMUST00000079952
Protein Domains
Histone H2A/H2B/H3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-L7MU04-F1-model_v2 AlphaFold L7MU04 1-110 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3643069 AgrOrtholog
Ensembl Genes ENSMUSG00000061065 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000079952 ENTREZGENE
  ENSMUST00000079952.4 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
InterPro Histone-fold UniProtKB/TrEMBL
  Histone_core_D UniProtKB/TrEMBL
  Histone_H2A UniProtKB/TrEMBL
KEGG Report mmu:333452 UniProtKB/TrEMBL
MGD MGI:3643069 ENTREZGENE
NCBI Gene 333452 ENTREZGENE
PANTHER HISTONE H2A UniProtKB/TrEMBL
  PTHR23430 UniProtKB/TrEMBL
Pfam Histone UniProtKB/TrEMBL
PhenoGen H2al1o PhenoGen
PRINTS HISTONEH2A UniProtKB/TrEMBL
SMART H2A UniProtKB/TrEMBL
Superfamily-SCOP Histone-fold UniProtKB/TrEMBL
UniProt L7MU04 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-27 H2al1o  H2A histone family member L1O  Gm5132  predicted gene 5132  Symbol and/or name change 5135510 APPROVED