Zfp36l3 (zinc finger protein 36, C3H type-like 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Zfp36l3 (zinc finger protein 36, C3H type-like 3) Mus musculus
Analyze
No known orthologs.
Symbol: Zfp36l3
Name: zinc finger protein 36, C3H type-like 3
RGD ID: 1618770
MGI Page MGI
Description: Enables mRNA 3'-UTR AU-rich region binding activity. Acts upstream of or within nuclear-transcribed mRNA poly(A) tail shortening. Located in cytoplasm. Is expressed in extraembryonic component; forebrain; olfactory epithelium; and placenta.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AY661338; mRNA decay activator protein ZFP36L3; zinc finger protein 36, C3H1 type-like 3; zinc finger protein 36-like 3
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X52,774,653 - 52,778,361 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX52,776,015 - 52,778,361 (-)EnsemblGRCm39 Ensembl
GRCm38X53,772,686 - 53,776,394 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX53,774,048 - 53,776,394 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X51,075,863 - 51,079,571 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X49,968,675 - 49,971,021 (-)NCBIMGSCv36mm8
CeleraX41,098,833 - 41,102,541 (-)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX30.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IDA)
membrane  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12466851   PMID:15814898   PMID:18367448   PMID:21267068   PMID:21873635   PMID:26952984  


Genomics

Variants

.
Variants in Zfp36l3
132 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:259
Count of miRNA genes:227
Interacting mature miRNAs:237
Transcripts:ENSMUST00000071711, ENSMUST00000165081
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
13208553Wght11_mweight 11 (mouse)X1186623959045360Mouse
13208557Lgth13_mbody length 13 (mouse)X1186623959045360Mouse
27226750Femd9_mfemur midshaft diameter 9, 10 week (mouse)X3333746355845360Mouse
27226780Femd12_mfemur midshaft diameter 12, 16 week (mouse)X3466365356845360Mouse
13208567Bmiq12_mbody mass index QTL 12 (mouse)X3526365377043606Mouse
1301009Pbwg7_mpostnatal body weight growth 7 (mouse)Not determinedX3911371473113814Mouse
4141565Pbwg21_mpostnatal body weight growth 21 (mouse)Not determinedX3911371473113814Mouse
1300794Spha2_msperm head anomaly 2 (mouse)Not determinedX3992149886260137Mouse
4142200Rtwq1_mreduced testis weight QTL 1 (mouse)Not determined4147706075477203Mouse
1301278Bdln1_mbody length 1 (mouse)Not determinedX4170210675702218Mouse
1300702Fcsa4_mfemoral cross-sectional area 4 (mouse)Not determinedX4602744480027567Mouse
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
1301351Obq6_mobesity QTL 6 (mouse)Not determinedX5077237570434751Mouse
25314311Syncl3_msynaptonemal complex length 3 (mouse)X5198887789743606Mouse
4142286Pubt1_mpubertal timing 1 (mouse)Not determined5241220061880496Mouse
4141126Lvic5_mliver iron content 5 (mouse)Not determined5241220063027567Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000071711   ⟹   ENSMUSP00000071630
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX52,776,015 - 52,778,361 (-)Ensembl
GRCm38.p6 EnsemblX53,774,048 - 53,776,394 (-)Ensembl
RefSeq Acc Id: NM_001009549   ⟹   NP_001009549
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X52,774,653 - 52,778,361 (-)NCBI
GRCm38X53,772,686 - 53,776,394 (-)ENTREZGENE
MGSCv37X51,075,863 - 51,079,571 (-)RGD
CeleraX41,098,833 - 41,102,541 (-)RGD
cM MapX ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001009549 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAV74249 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000071630
  ENSMUSP00000071630.4
GenBank Protein Q5ISE2 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001009549   ⟸   NM_001009549
- UniProtKB: Q5ISE2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000071630   ⟸   ENSMUST00000071711

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5ISE2-F1-model_v2 AlphaFold Q5ISE2 1-725 view protein structure

Promoters
RGD ID:6846545
Promoter ID:MM_KWN:60330
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:NM_001009549,   OTTMUST00000042176
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X51,077,406 - 51,077,906 (-)MPROMDB
RGD ID:13680510
Promoter ID:EPDNEW_M24404
Type:initiation region
Name:Zfp36l3_1
Description:Mus musculus zinc finger protein 36, C3H type-like 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X53,776,309 - 53,776,369EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3525151 AgrOrtholog
Ensembl Genes ENSMUSG00000059334 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000071711 ENTREZGENE
  ENSMUST00000071711.4 UniProtKB/Swiss-Prot
Gene3D-CATH Zinc finger, CCCH-type UniProtKB/Swiss-Prot
InterPro Trimer_LpxA-like_sf UniProtKB/Swiss-Prot
  ZFP36-like UniProtKB/Swiss-Prot
  Znf_CCCH UniProtKB/Swiss-Prot
  Znf_CCCH_sf UniProtKB/Swiss-Prot
KEGG Report mmu:333473 UniProtKB/Swiss-Prot
MGD MGI:3525151 ENTREZGENE
NCBI Gene 333473 ENTREZGENE
PANTHER MRNA DECAY ACTIVATOR PROTEIN ZFP36L3 UniProtKB/Swiss-Prot
  PTHR12547 UniProtKB/Swiss-Prot
Pfam zf-CCCH UniProtKB/Swiss-Prot
PhenoGen Zfp36l3 PhenoGen
PROSITE ZF_C3H1 UniProtKB/Swiss-Prot
SMART ZnF_C3H1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51161 UniProtKB/Swiss-Prot
  SSF90229 UniProtKB/Swiss-Prot
UniProt Q5ISE2 ENTREZGENE, UniProtKB/Swiss-Prot