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Gene: Ube2u (ubiquitin-conjugating enzyme E2U (putative)) Mus musculus

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Symbol:

Ube2u

Name:

ubiquitin-conjugating enzyme E2U (putative)

RGD ID:

1618757

MGI Page

MGI

Description:

Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in anaphase-promoting complex-dependent catabolic process; protein polyubiquitination; and regulation of mitotic metaphase/anaphase transition. Predicted to be active in nucleus. Is expressed in brain; oviduct; spinal cord; and testis. Orthologous to human UBE2U (ubiquitin conjugating enzyme E2 U).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ubiquitin-conjugating enzyme E2 U; ubiquitin-conjugating enzyme E2U

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	100,336,064 - 100,407,342 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	100,336,046 - 100,407,344 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	100,478,867 - 100,550,145 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	100,478,849 - 100,550,147 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	100,151,472 - 100,222,750 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	99,976,799 - 100,048,077 (+)	NCBI		MGSCv36	mm8
Celera	4	98,839,063 - 98,910,791 (+)	NCBI		Celera
Cytogenetic Map	4	C6	NCBI
cM Map	4	45.72	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital disorder of glycosylation It (ISO)

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

1H-pyrazole (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (EXP)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

carbon nanotube (EXP)

CGP 52608 (ISO)

endosulfan (ISO)

epoxiconazole (EXP)

fenvalerate (ISO)

mono(2-ethylhexyl) phthalate (EXP)

ozone (EXP)

paracetamol (ISO)

pioglitazone (EXP)

pirinixic acid (EXP)

silicon dioxide (ISO)

tetrachloromethane (EXP)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anaphase-promoting complex-dependent catabolic process (IBA)

protein polyubiquitination (IBA)

regulation of mitotic metaphase/anaphase transition (IBA)

Cellular Component

nucleus (IBA)

Molecular Function

protein binding (ISO)

ubiquitin conjugating enzyme activity (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

ubiquitin/proteasome degradation pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased basophil cell number (IEA)

no abnormal phenotype detected (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
2.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:16141072	PMID:16141073	PMID:21267068	PMID:21677750	PMID:21873635	PMID:24194600
PMID:27357688	PMID:27626380	PMID:38355793

Genomics

Comparative Map Data

Ube2u
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	100,336,064 - 100,407,342 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	100,336,046 - 100,407,344 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	100,478,867 - 100,550,145 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	100,478,849 - 100,550,147 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	100,151,472 - 100,222,750 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	99,976,799 - 100,048,077 (+)	NCBI		MGSCv36	mm8
Celera	4	98,839,063 - 98,910,791 (+)	NCBI		Celera
Cytogenetic Map	4	C6	NCBI
cM Map	4	45.72	NCBI

UBE2U
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	64,203,623 - 64,267,368 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	64,203,623 - 64,267,368 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	64,669,306 - 64,733,051 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	64,442,078 - 64,482,615 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	62,959,589 - 63,000,068 (+)	NCBI		Celera
Cytogenetic Map	1	p31.3	NCBI
HuRef	1	62,778,392 - 62,818,851 (+)	NCBI		HuRef
CHM1_1	1	64,785,215 - 64,825,697 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	64,078,756 - 64,143,219 (+)	NCBI		T2T-CHM13v2.0

Ube2u
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	120,233,749 - 120,301,514 (+)	NCBI		GRCr8
mRatBN7.2	5	115,118,234 - 115,187,296 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	115,118,495 - 115,186,874 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	118,574,647 - 118,642,810 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	118,574,801 - 118,642,863 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	122,502,926 - 122,571,096 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	121,128,675 - 121,196,288 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	113,665,335 - 113,733,160 (+)	NCBI		Celera
Cytogenetic Map	5	q33	NCBI

Ube2u
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955423	25,973,131 - 26,017,733 (-)	NCBI	ChiLan1.0	ChiLan1.0

UBE2U
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	162,588,031 - 162,652,315 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	161,738,576 - 161,802,902 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	63,458,063 - 63,521,812 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	65,346,777 - 65,389,265 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	65,346,777 - 65,410,228 (+)	Ensembl	panpan1.1		panPan2

UBE2U
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	45,947,637 - 45,998,353 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	45,947,639 - 45,997,722 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	46,005,599 - 46,055,826 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	46,124,819 - 46,175,053 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	46,124,821 - 46,175,032 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	46,087,154 - 46,137,423 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	46,033,137 - 46,083,352 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	46,290,882 - 46,341,107 (-)	NCBI		UU_Cfam_GSD_1.0

Ube2u
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	77,399,087 - 77,495,543 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936692	1,714,511 - 1,792,910 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936692	1,714,533 - 1,765,348 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UBE2U
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	148,233,412 - 148,305,330 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	148,233,498 - 148,314,193 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	136,685,350 - 136,757,434 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UBE2U
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	68,799,501 - 68,865,893 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666033	48,649,297 - 48,711,899 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Ube2u
4063 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	565
Count of miRNA genes:	235
Interacting mature miRNAs:	240
Transcripts:	ENSMUST00000092730, ENSMUST00000106979, ENSMUST00000133493
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
27226782	Tibl2_m	tibia length 2, 5 week (mouse)					4	90888237	111257197	Mouse
13824982	Svwq1_m	seminal vesicle weight QTL 1 (mouse)					4	89888237	118857197	Mouse
11532714	Sluc43_m	susceptibility to lung cancer 43 (mouse)					4	46642108	123127211	Mouse
12904002	Opfaq9_m	open field activity QTL 9 (mouse)					4	92975790	126975790	Mouse
4141623	W6q13_m	weight 6 weeks QTL 13 (mouse)			Not determined			88982069	140468203	Mouse
25314312	Syncl2_m	synaptonemal complex length 2 (mouse)					4	65718237	146584457	Mouse
1357726	Lnopy1_m	lens opacity 1 (mouse)			Not determined		4	85428838	119429037	Mouse
11532708	Sluc43i_m	susceptibility to lung cancer 43i (mouse)					4	74444699	108444983	Mouse
11532707	Sluc43h_m	susceptibility to lung cancer 43h (mouse)					4	74444699	108444983	Mouse
11532706	Sluc43c_m	susceptibility to lung cancer 43c (mouse)					4	74444699	108444983	Mouse
27226770	Tibl11_m	tibia length 11, 10 week (mouse)					4	88518237	108357197	Mouse
11532705	Sluc43b_m	susceptibility to lung cancer 43b (mouse)					4	74444699	108444983	Mouse
1302044	Nss1_m	NOD Sjogren's syndrome 1 (mouse)			Not determined		4	71982069	105982216	Mouse
11532704	Sluc43a_m	susceptibility to lung cancer 43a (mouse)					4	74444699	108444983	Mouse
14696687	Gdq1_m	grooming duration QTL 1, males (mouse)					4	96888237	111857197	Mouse
27226766	Tibl17_m	tibia length 17, 16 week (mouse)					4	88518237	108457197	Mouse
27226760	Feml19_m	femur length 19, 16 week (mouse)					4	90888237	108457197	Mouse
4141093	W3q17_m	weight 3 weeks QTL 17 (mouse)			Not determined			88982069	140468203	Mouse
1302031	Bulb1_m	bulb size 1 (mouse)			Not determined		4	74033887	108034029	Mouse
27095939	Ulnl9_m	ulna length 9, 16 week (mouse)					4	65318237	118857197	Mouse
11567249	Elorr3_m	ethanol induced loss of righting response 3 (mouse)					4	3722677	156268235	Mouse
12904933	Edlmmq3_m	extensor digitorum longus muscle mass QTL 3 (mouse)					4	81213991	115213991	Mouse
1301815	Sles2_m	systemic lupus erythmatosus suppressor 2 (mouse)			Not determined		4	94957579	150676858	Mouse
1300918	Stheal4_m	soft tissue heal 4 (mouse)			Not determined		4	89969627	123969747	Mouse
1301556	Cd4vts1_m	CD4 virgin T cell subset 1 (mouse)			Not determined		4	85428838	119429037	Mouse
1301823	Bmd7_m	bone mineral density 7 (mouse)			Not determined		4	88982069	151654550	Mouse
27226801	Feml6_m	femur length 6, 5 week (mouse)					4	87518237	103257197	Mouse
1302204	Spm1_m	splenomegaly modifier (mouse)			Not determined		4	82244395	116244582	Mouse
11532703	Sluc43g_m	susceptibility to lung cancer 43g (mouse)					4	74444699	108444983	Mouse
11532702	Sluc43f_m	susceptibility to lung cancer 43f (mouse)					4	74444699	108444983	Mouse
11532701	Sluc43e_m	susceptibility to lung cancer 43e (mouse)					4	74444699	108444983	Mouse
1558948	Ath8_m	atherosclerosis 8 (mouse)			Not determined		4	45658442	105156995	Mouse
11532700	Sluc43d_m	susceptibility to lung cancer 43d (mouse)					4	74444699	108444983	Mouse
11039517	Ltpr4_m	Leishmania tropica response 4 (mouse)					4	79365751	113365867	Mouse
11039504	Ltpr4a_m	Leishmania tropica response 4a (mouse)					4	79365751	113365867	Mouse
11039505	Ltpr4c_m	Leishmania tropica response 4c (mouse)					4	79365751	113365867	Mouse
1301930	Papg1_m	pulmonary adenoma progression 1 (mouse)			Not determined		4	85781167	119781279	Mouse
1302057	Pgia27_m	proteoglycan induced arthritis 27 (mouse)			Not determined		4	70067227	104067464	Mouse
1301545	Gauc_m	glucose area under curve (mouse)			Not determined		4	76763107	110763305	Mouse
11039506	Ltpr4b_m	Leishmania tropica response 4b (mouse)					4	79365751	113365867	Mouse
13208562	Wght7_m	weight 7 (mouse)					4	90888237	148084457	Mouse
27226787	Feml14_m	femur length 14, 10 week (mouse)					4	84918237	107157197	Mouse
10412193	Plep_m	plasma lepin levels (mouse)			Not determined		4	74444699	108444983	Mouse
27095900	Scvln9_m	sacral vertebrae length 2, 10 week (mouse)					4	68018237	107157197	Mouse
39128212	Lwq21_m	liver weight QTL 21 (mouse)					4	88982069	140468203	Mouse
27226716	Metcl2_m	metatarsal-calcaneal length 2, 5 week (mouse)					4	88118237	118557197	Mouse
1301847	Fecq2_m	fecundity QTL 2 (mouse)			Not determined		4	100071971	134072206	Mouse
26884445	Sklq7_m	skull length QTL 7, 10 week (mouse)					4	68018237	150884457	Mouse
26884434	Zlq1_m	zygomatic length QTL 1, 5 week (mouse)					4	53700000	103257197	Mouse
26884435	Zlq4_m	zygomatic length QTL 4, 10 week (mouse)					4	85118237	104957197	Mouse
1300697	Sle2_m	systemic lupus erythmatosus susceptibility 2 (mouse)			Not determined		4	77957579	111957775	Mouse
1301597	Anxty_m	anxiety (mouse)			Not determined		4	74137574	128009280	Mouse
26884437	Sklq13_m	skull length QTL 13, 16 week (mouse)					4	57700000	155684457	Mouse
4141549	W10q10_m	weight 10 weeks QTL 10 (mouse)			Not determined			88982069	140468203	Mouse
1357895	Ctrcts_m	cataract severity (mouse)			Not determined		4	45709925	138342753	Mouse
26884431	Zlq8_m	zygomatic length QTL 8, 16 week (mouse)					4	74718237	108357197	Mouse
12879897	Berr4_m	berghei resistance locus 4 (mouse)					4	71982069	105982216	Mouse
4142047	Mvwf3_m	modifier of von Willebrand factor 3 (mouse)			Not determined			14010457	117072206	Mouse
1301106	Skts7_m	skin tumor susceptibility 7 (mouse)			Not determined		4	100071971	134072206	Mouse
1301233	Sbw2_m	splenomegaly-NZB x NZW 2 (mouse)			Not determined		4	94957579	128009280	Mouse
27226746	Metcl8_m	metatarsal-calcaneal length 8, 10 week (mouse)					4	87518237	107157197	Mouse
27095924	Pglq2_m	pelvic girdle length QTL 2, 5 week (mouse)					4	69118237	130727311	Mouse
27095927	Pglq7_m	pelvic girdle length QTL 7, 10 week (mouse)					4	88118237	108357197	Mouse
27095921	Pglq12_m	pelvic girdle length QTL 12, 16 week (mouse)					4	83118237	108357197	Mouse
27226739	Metcl14_m	metatarsal-calcaneal length 14, 16 week (mouse)					4	87518237	108357197	Mouse
1357561	Mbsyd_m	metabolic syndrome (mouse)			Not determined		4	66888445	100888588	Mouse
1301118	Bbaa23_m	B.burgdorferi-associated arthritis 23 (mouse)			Not determined		4	85781167	119781279	Mouse
11532738	Abd1_m	autoimmune biliary disease 1 (mouse)					4	88982069	116271120	Mouse
15039368	Nmrs19_m	NAFLD-associated magnetic resonance shift 19 (mouse)					4	90882780	124882780	Mouse
1301757	Tlsr4_m	thymic lymphoma suppressor region 4 (mouse)			Not determined		4	66757130	100757258	Mouse
27095917	Scvln14_m	sacral vertebrae length 2, 16 week (mouse)					4	68018237	130277062	Mouse
1301731	Cafq2_m	caffeine metabolism QTL 2 (mouse)			Not determined		4	94732255	128732454	Mouse
4141900	Skts-fp1_m	skin tumor susceptibility in FVB and PWK 1 (mouse)			Not determined		4	53550839	124055180	Mouse
1300966	Pabr2_m	plasma apolipoprotein B (human) regulator 2 (mouse)			Not determined		4	46332646	105801860	Mouse
1300580	Lbw2_m	lupus NZB x NZW 2 (mouse)			Not determined		4	98545539	128009280	Mouse
1301739	Pitm2_m	prion incubation time 2 (mouse)			Not determined		4	71982069	105982216	Mouse
1301867	Idd11_m	insulin dependent diabetes susceptibility 11 (mouse)			Not determined		4	83604870	117605006	Mouse
26884449	Sklq2_m	skull length QTL 2, 5 week (mouse)					4	36700000	128993793	Mouse
27226724	Tibw2_m	tibia width 2, proximal, 10 week (mouse)					4	43000000	108357197	Mouse
27095905	Scvln3_m	sacral vertebrae length 2, 5 week (mouse)					4	55600000	128993793	Mouse
11553870	Cmmm_m	carcinoma modifier of MSM (mouse)					4	90590668	124590781	Mouse

Markers in Region

D1S2673

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	4	100,482,609 - 100,483,588	UniSTS	GRCm38
MGSCv37	4	100,155,214 - 100,156,193	UniSTS	GRCm37
Celera	4	98,842,775 - 98,843,782	UniSTS
Cytogenetic Map	4	C6	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AK133379	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL670290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AV266581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BB616918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC150880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC150888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC172031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000092730 ⟹ ENSMUSP00000090406

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	4	100,336,064 - 100,407,342 (+)	Ensembl
GRCm38.p6 Ensembl	4	100,478,867 - 100,550,145 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000133493 ⟹ ENSMUSP00000137472

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	4	100,336,046 - 100,407,344 (+)	Ensembl
GRCm38.p6 Ensembl	4	100,478,849 - 100,550,147 (+)	Ensembl

RefSeq Acc Id:

NM_001033773 ⟹ NP_001028945

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	4	100,336,064 - 100,407,342 (+)	NCBI
GRCm38	4	100,478,867 - 100,550,145 (+)	ENTREZGENE
MGSCv37	4	100,151,472 - 100,222,750 (+)	RGD
Celera	4	98,839,063 - 98,910,791 (+)	RGD
cM Map	4		ENTREZGENE

Sequence:

show sequence

AGAAAGAGAACTTGGCAGTGCTGCTTCGGGTTTGCATTTTTTTCCTCTTGGCCAGCCAACAACT
CCGGCATCTCTCAAGTGGTCCCCAAGTTTGTCTAGGGGTGGAAGCTGAGACAGCCCAGATAGGA
AAGACCCCAGTCTTCCTTCGGGAAGTTCCCGTCTGGAGGAGTCAGAAAAGAAAGTCACTGTTAA
ATCCTAATCTTAGCAGTTACTTGACTACGGAGTGAGTAACCGTTAACCAGGGGTCAGAGGGTGA
CCGGAGACCTCAGTCAGGAACTCTGCCCTGAGTAAACCAAGACAAGTAGCAACCTCAGTATGTA
CTCCAAAGCTTACATCTTGCTGGAAAGAGAATTCAGGGAGTTAAAACGTGACACAAGAAAGGAT
ATTACTGCTTATCCTGTAAGTGATGATATGATGAATTGGAAAGCTGAGATTGAAGGTCTTCGCA
ATTCAGTTTGTGAAGGACTTGTTTTCTACCTGACATTAGAGTTTTCACAAGAGTACAATTCTGT
TCCTCCAAATGTGAAATTTACAACAATTCCTTTTCATCCAAATGTAGACCCATATACCGGTAAA
CCCAGTATAGACTTTTTGGACAAGCCTGGCAAGTGGAACACGAATTATACAGTACTCAGCATCT
TACTTGATCTACAGATGTTGCTTTCTTACCCTGTCCTAAAAAATCCAGTGAACTTGGAGGCAGC
CCAACTGCTGATTAGAAATGCGTCTACGTATAAAATGGTAATTCAGGAACTTTTGCCGCCAGCA
TTACCAAAAAGAGAGAGCAGCCTGGTGATACCTGAAAAGCCACAGGATCGAGTCAGGGTAATTA
AAACAATCTCATTTAATGATTACTACAAGACATGGTCTCAGATAGCCACGACAAAAGTCGCAGA
ACACTCCAGAAACCCATTTGTTGGAGATCCACATTTCATGGGACAGTATTACAAATGGAAGCAA
CAGGATCGGCAGAATCAAGTGCAATGGGAGTCCAAGTTTGCACTCTCAAAGTGGCAGACTGCTA
GGAAAAAAATAATGGCTCAGGAAAAGAGCAATCACTACAACCAAGTGATAGGTATCTACCCATC
TCCGAGTGAACTTTCTTTTGAATATGAAATAGAAGAAGAAGAAGAAGAAGAAGAAGAGGAGGAG
GAGGAGGAGGAGGAGGAAGAAGAAGAAGAAGAAAAAGAAGAAGAAGAAGAAGAACCAAGGATTT
ATCAAATACCTCAGGAGTGGCCAGAAGAACATGATTCAAAAGAATCCTGGGAAGAGGAAGCAGA
CCACCTGGTCTCCTGGACCAATGGTCTTGATGAAGAATCTTTGAACTATGAGTACTTTGACAAC
GTAAAGAACTATGAGAACTTGGGCAACTAACACACAAGGACTTTACACACTGCCCTATTACAGT
GCAGTCTCAGGGAACAGTTTTAGGAGATGCTCAGGACCTGGCTTCTGCTCTCTACCCCAGTTGA
TCTCATCTTTCTGGAAGCACAAAATAGAAAATACAAGTATAAGCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001028945	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI50881	(Get FASTA)	NCBI Sequence Viewer
	AAI50889	(Get FASTA)	NCBI Sequence Viewer
	AAI72031	(Get FASTA)	NCBI Sequence Viewer
	BAE21623	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000090406.4
	ENSMUSP00000137472
	ENSMUSP00000137472.2

RefSeq Acc Id:

NP_001028945 ⟸ NM_001033773

- UniProtKB:

B1AUC4 (UniProtKB/TrEMBL), B7ZWG1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYSKAYILLEREFRELKRDTRKDITAYPVSDDMMNWKAEIEGLRNSVCEGLVFYLTLEFSQEYN
SVPPNVKFTTIPFHPNVDPYTGKPSIDFLDKPGKWNTNYTVLSILLDLQMLLSYPVLKNPVNLE
AAQLLIRNASTYKMVIQELLPPALPKRESSLVIPEKPQDRVRVIKTISFNDYYKTWSQIATTKV
AEHSRNPFVGDPHFMGQYYKWKQQDRQNQVQWESKFALSKWQTARKKIMAQEKSNHYNQVIGIY
PSPSELSFEYEIEEEEEEEEEEEEEEEEEEEEEEKEEEEEEPRIYQIPQEWPEEHDSKESWEEE
ADHLVSWTNGLDEESLNYEYFDNVKNYENLGN

hide sequence

Ensembl Acc Id:

ENSMUSP00000137472 ⟸ ENSMUST00000133493

Ensembl Acc Id:

ENSMUSP00000090406 ⟸ ENSMUST00000092730

Protein Domains

UBC core

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B1AUC4-F1-model_v2	AlphaFold	B1AUC4	1-352	view protein structure

Promoters

RGD ID:

6836599

Promoter ID:

MM_KWN:38634

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Kidney

Transcripts:

NM_001033773, OTTMUST00000018146, OTTMUST00000018147

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	4	100,151,396 - 100,151,896 (+)	MPROMDB

RGD ID:

6883950

Promoter ID:

EPDNEW_M5426

Type:

initiation region

Name:

Ube2u_1

Description:

Mus musculus ubiquitin-conjugating enzyme E2U , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	4	100,478,856 - 100,478,916	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3588216	AgrOrtholog
Ensembl Genes	ENSMUSG00000069733	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000092730.5	UniProtKB/TrEMBL
	ENSMUST00000133493	ENTREZGENE
	ENSMUST00000133493.9	UniProtKB/TrEMBL
Gene3D-CATH	3.10.110.10	UniProtKB/TrEMBL
InterPro	Ub_conjugating_enzyme	UniProtKB/TrEMBL
	UBQ-conjugat_E2	UniProtKB/TrEMBL
	UBQ-conjugating_enzyme/RWD	UniProtKB/TrEMBL
KEGG Report	mmu:381534	UniProtKB/TrEMBL
MGD	MGI:3588216	ENTREZGENE
NCBI Gene	381534	ENTREZGENE
PANTHER	UBIQUITIN-CONJUGATING ENZYME E2	UniProtKB/TrEMBL
Pfam	UQ_con	UniProtKB/TrEMBL
PhenoGen	Ube2u	PhenoGen
PROSITE	UBIQUITIN_CONJUGAT_2	UniProtKB/TrEMBL
SMART	UBCc	UniProtKB/TrEMBL
Superfamily-SCOP	UBQ-conjugat/RWD-like	UniProtKB/TrEMBL
UniProt	B1AUC4	ENTREZGENE, UniProtKB/TrEMBL
	B7ZWG1	ENTREZGENE, UniProtKB/TrEMBL
	Q3V081_MOUSE	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

Mammalian Phenotype