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Gene: H2-Q2 (histocompatibility 2, Q region locus 2) Mus musculus
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Symbol: H2-Q2
Name: histocompatibility 2, Q region locus 2
Description: Predicted to have several functions, including TAP complex binding activity; beta-2-microglobulin binding activity; and signaling receptor binding activity. Involved in female pregnancy and growth. Predicted to localize to several cellular components, including the Golgi medial cisterna; MHC class I protein complex; and endoplasmic reticulum. Human ortholog(s) of this gene implicated in Stevens-Johnson syndrome; allergic asthma; human immunodeficiency virus infectious disease; and psoriasis 1. Is expressed in brain; small intestine; and thymus. Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A) and HLA-F (major histocompatibility complex, class I, F); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BE136769; class Ib major histocompatibility complex; ENSMUSG00000079507; expressed sequence BE136769; Gm11132; gs14-2; H-2Q2; H2-D1; H2-K1; MHC class II antigen D; MHC class II antigen K; MHC classIb like protein GS14-2
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381735,342,307 - 35,346,764 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371735,479,278 - 35,482,667 (+)NCBIGRCm37mm9NCBIm37
MGSCv361734,950,386 - 34,953,775 (+)NCBImm8
Celera1738,424,425 - 38,427,814 (+)NCBICelera
Cytogenetic Map17 B1NCBI
cM Map1718.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on H2-Q2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1618431
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.