Nudt16l2 (nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 2) - Rat Genome Database
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Gene: Nudt16l2 (nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 2) Mus musculus
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Symbol: Nudt16l2
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 2
RGD ID: 1618303
MGI Page MGI
Description: Predicted to have several functions, including m7G(5')pppN diphosphatase activity; nucleotide phosphatase activity, acting on free nucleotides; and phosphodiesterase decapping endonuclease activity. Predicted to be involved in mRNA catabolic process and snoRNA catabolic process. Predicted to localize to nucleus. Is expressed in testis. Orthologous to several human genes including NUDT16 (nudix hydrolase 16); INTERACTS WITH aflatoxin B1 (ortholog); antirheumatic drug (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700080E11Rik; AI429110; hypothetical protein LOC73532; nudix motif 16-like; RIKEN cDNA 1700080E11 gene; testis specific expressed protein 8; Tseg8; U8 snoRNA-decapping enzyme-like; uncharacterized protein LOC73532
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399105,020,543 - 105,022,281 (-)NCBIGRCm39mm39
GRCm389105,143,344 - 105,145,082 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9105,143,342 - 105,145,092 (-)EnsemblGRCm38mm10GRCm38
MGSCv379105,045,674 - 105,047,412 (-)NCBIGRCm37mm9NCBIm37
MGSCv369105,001,444 - 105,003,182 (-)NCBImm8
Celera9104,729,244 - 104,730,978 (-)NCBICelera
Cytogenetic Map9F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15939374   PMID:16141072   PMID:16141073   PMID:16602821   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Nudt16l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399105,020,543 - 105,022,281 (-)NCBIGRCm39mm39
GRCm389105,143,344 - 105,145,082 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9105,143,342 - 105,145,092 (-)EnsemblGRCm38mm10GRCm38
MGSCv379105,045,674 - 105,047,412 (-)NCBIGRCm37mm9NCBIm37
MGSCv369105,001,444 - 105,003,182 (-)NCBImm8
Celera9104,729,244 - 104,730,978 (-)NCBICelera
Cytogenetic Map9F1NCBI
NUDT16L2P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3131,361,898 - 131,365,122 (+)EnsemblGRCh38hg38GRCh38
GRCh383131,361,845 - 131,365,122 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373131,080,689 - 131,083,966 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363132,563,428 - 132,566,656 (+)NCBINCBI36hg18NCBI36
Celera3129,506,361 - 129,509,638 (+)NCBI
Cytogenetic Map3q22.1NCBI
HuRef3128,465,504 - 128,468,781 (+)NCBIHuRef
CHM1_13131,044,278 - 131,047,555 (+)NCBICHM1_1

Position Markers
AI429110  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389105,143,389 - 105,143,498UniSTSGRCm38
MGSCv379105,045,719 - 105,045,828UniSTSGRCm37
Celera9104,729,289 - 104,729,398UniSTS
Cytogenetic Map9F1UniSTS
Whitehead/MRC_RH91080.89UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:144
Count of miRNA genes:138
Interacting mature miRNAs:143
Transcripts:ENSMUST00000035180
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000035180   ⟹   ENSMUSP00000035180
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9105,143,342 - 105,145,092 (-)Ensembl
RefSeq Acc Id: ENSMUST00000190661   ⟹   ENSMUSP00000139516
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9105,144,312 - 105,145,076 (-)Ensembl
RefSeq Acc Id: NM_028562   ⟹   NP_082838
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399105,020,543 - 105,022,281 (-)NCBI
GRCm389105,143,344 - 105,145,082 (-)ENTREZGENE
MGSCv379105,045,674 - 105,047,412 (-)RGD
Celera9104,729,244 - 104,730,978 (-)RGD
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_082838 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH48436 (Get FASTA)   NCBI Sequence Viewer  
  ACO25356 (Get FASTA)   NCBI Sequence Viewer  
  BAB24803 (Get FASTA)   NCBI Sequence Viewer  
  EDL21102 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_082838   ⟸   NM_028562
- UniProtKB: E9Q9G1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000035180   ⟸   ENSMUST00000035180
RefSeq Acc Id: ENSMUSP00000139516   ⟸   ENSMUST00000190661
Protein Domains
Nudix hydrolase

Promoters
RGD ID:8670676
Promoter ID:EPDNEW_M13369
Type:multiple initiation site
Name:1700080E11Rik_1
Description:Mus musculus RIKEN cDNA 1700080E11 gene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389105,145,092 - 105,145,152EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920782 AgrOrtholog
Ensembl Genes ENSMUSG00000032566 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000035180 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000139516 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000035180 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000190661 UniProtKB/TrEMBL
InterPro NUDIX_hydrolase_dom UniProtKB/TrEMBL
  NUDIX_hydrolase_dom-like UniProtKB/TrEMBL
KEGG Report mmu:73532 UniProtKB/TrEMBL
MGD MGI:1920782 ENTREZGENE
NCBI Gene 73532 ENTREZGENE
PhenoGen Nudt16l2 PhenoGen
PROSITE NUDIX UniProtKB/TrEMBL
Superfamily-SCOP NUDIX_hydrolase UniProtKB/TrEMBL
UniProt C9W8M5_MOUSE UniProtKB/TrEMBL
  E9Q9G1 ENTREZGENE, UniProtKB/TrEMBL
  Q80ZT6_MOUSE UniProtKB/TrEMBL
  Q9D9G6_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-26 Nudt16l2  nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 2  1700080E11Rik  RIKEN cDNA 1700080E11 gene  Symbol and/or name change 5135510 APPROVED