Meikin (meiotic kinetochore factor) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Meikin (meiotic kinetochore factor) Mus musculus
Analyze
Symbol: Meikin
Name: meiotic kinetochore factor
RGD ID: 1618295
MGI Page MGI
Description: Acts upstream of or within meiotic chromosome segregation. Located in kinetochore. Orthologous to human MEIKIN (meiotic kinetochore factor); INTERACTS WITH bisphenol A (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930404A10Rik; hypothetical protein LOC74847; MGC130346; RP23-297J14.3; uncharacterized protein LOC74847
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391154,261,478 - 54,317,616 (+)NCBIGRCm39mm39
GRCm39 Ensembl1154,261,478 - 54,317,616 (+)Ensembl
GRCm381154,370,652 - 54,426,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1154,370,652 - 54,426,790 (+)EnsemblGRCm38mm10GRCm38
MGSCv371154,184,154 - 54,240,257 (+)NCBIGRCm37mm9NCBIm37
MGSCv361154,205,542 - 54,270,213 (+)NCBImm8
Celera1158,959,563 - 59,014,489 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. RGD automated import pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:25533956   PMID:32032549  


Genomics

Comparative Map Data
Meikin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391154,261,478 - 54,317,616 (+)NCBIGRCm39mm39
GRCm39 Ensembl1154,261,478 - 54,317,616 (+)Ensembl
GRCm381154,370,652 - 54,426,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1154,370,652 - 54,426,790 (+)EnsemblGRCm38mm10GRCm38
MGSCv371154,184,154 - 54,240,257 (+)NCBIGRCm37mm9NCBIm37
MGSCv361154,205,542 - 54,270,213 (+)NCBImm8
Celera1158,959,563 - 59,014,489 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
MEIKIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5131,806,990 - 131,945,698 (-)EnsemblGRCh38hg38GRCh38
GRCh385131,806,990 - 131,945,663 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,142,683 - 131,281,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,242,497 - 131,309,290 (-)NCBINCBI36hg18NCBI36
Celera5127,344,687 - 127,411,474 (-)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5126,335,199 - 126,473,954 (-)NCBIHuRef
CHM1_15130,575,716 - 130,714,237 (-)NCBICHM1_1
Meikin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21038,508,156 - 38,556,732 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1038,508,170 - 38,556,546 (+)Ensembl
Rnor_6.01039,726,373 - 39,776,458 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1039,726,507 - 39,751,398 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01039,497,672 - 39,549,480 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,788,007 - 39,836,674 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1037,848,433 - 37,898,013 (+)NCBICelera
Cytogenetic Map10q22NCBI
Meikin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554083,244,704 - 3,331,985 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554083,245,147 - 3,331,795 (-)NCBIChiLan1.0ChiLan1.0
MEIKIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15133,394,105 - 133,533,078 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5133,394,105 - 133,533,078 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05127,229,311 - 127,369,783 (-)NCBIMhudiblu_PPA_v0panPan3
MEIKIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,143,941 - 20,221,665 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,144,240 - 20,220,105 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1118,939,803 - 19,017,311 (-)NCBI
ROS_Cfam_1.01120,921,647 - 20,999,376 (-)NCBI
UMICH_Zoey_3.11119,648,957 - 19,726,534 (-)NCBI
UNSW_CanFamBas_1.01119,496,455 - 19,574,027 (-)NCBI
UU_Cfam_GSD_1.01120,137,787 - 20,215,615 (-)NCBI
Meikin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213116,215,578 - 116,272,902 (+)NCBI
SpeTri2.0NW_0049366473,218,383 - 3,270,571 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEIKIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,116,008 - 134,207,138 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,103,568 - 134,208,250 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22139,473,126 - 139,563,654 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MEIKIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12334,648,698 - 34,779,680 (-)NCBI
Vero_WHO_p1.0NW_02366603443,178,775 - 43,311,699 (+)NCBI
Meikin
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473340,161,901 - 40,243,260 (+)NCBI

Position Markers
RH136092  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381154,401,050 - 54,401,245UniSTSGRCm38
MGSCv371154,214,552 - 54,214,747UniSTSGRCm37
Celera1158,988,832 - 58,989,027UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map11B1.3UniSTS
AW050338  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381154,364,345 - 54,364,459UniSTSGRCm38
MGSCv371154,177,847 - 54,177,961UniSTSGRCm37
Celera1158,952,876 - 58,952,990UniSTS
Cytogenetic Map11B1.3UniSTS
Whitehead/MRC_RH11734.88UniSTS
AA943188  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381154,361,983 - 54,362,143UniSTSGRCm38
MGSCv371154,175,485 - 54,175,645UniSTSGRCm37
Celera1158,950,514 - 58,950,674UniSTS
Cytogenetic Map11B1.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2127257955272579Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112588179959881914Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5417484463428696Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115419011565213015Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:97
Interacting mature miRNAs:101
Transcripts:ENSMUST00000094193, ENSMUST00000143919
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000094193   ⟹   ENSMUSP00000091745
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1154,261,478 - 54,317,616 (+)Ensembl
GRCm38.p6 Ensembl1154,370,652 - 54,426,790 (+)Ensembl
RefSeq Acc Id: ENSMUST00000143919
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1154,261,478 - 54,317,581 (+)Ensembl
GRCm38.p6 Ensembl1154,370,652 - 54,426,755 (+)Ensembl
RefSeq Acc Id: NM_029105   ⟹   NP_083381
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391154,261,478 - 54,317,616 (+)NCBI
GRCm381154,370,652 - 54,426,790 (+)NCBI
MGSCv371154,184,154 - 54,240,257 (+)RGD
Celera1158,959,563 - 59,014,524 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_083381 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI07369 (Get FASTA)   NCBI Sequence Viewer  
  BAB29701 (Get FASTA)   NCBI Sequence Viewer  
  BAP91161 (Get FASTA)   NCBI Sequence Viewer  
  Q5F2C3 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_083381   ⟸   NM_029105
- UniProtKB: Q5F2C3 (UniProtKB/Swiss-Prot),   Q9D5P1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000091745   ⟸   ENSMUST00000094193

Promoters
RGD ID:8674658
Promoter ID:EPDNEW_M15360
Type:multiple initiation site
Name:Meikin_1
Description:Mus musculus meiotic kinetochore factor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381154,370,609 - 54,370,669EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922097 AgrOrtholog
Ensembl Genes ENSMUSG00000020332 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000091745 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000094193 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Meikin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:74847 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1922097 ENTREZGENE
NCBI Gene 74847 ENTREZGENE
PANTHER PTHR38006 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Meikin PhenoGen
UniProt MEIKN_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9D5P1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q3KNB2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-02-03 Meikin  meiotic kinetochore factor  4930404A10Rik  RIKEN cDNA 4930404A10 gene  Symbol and/or name change 5135510 APPROVED