Gene: Amy2a5 (amylase 2a5) Mus musculus
Analyze
Symbol:
Amy2a5
Name:
amylase 2a5
Description:
Exhibits amylase activity. Localizes to the extracellular space. Orthologous to several human genes including AMY1A (amylase alpha 1A); AMY2A (amylase alpha 2A); and AMY2B (amylase alpha 2B); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
1,4-alpha-D-glucan glucanohydrolase; 1810008N23Rik; Amy-2; Amy2; amylase 2, pancreatic; amylase 2a5, pancreatic; mAmy2-2; PA; pancreatic alpha-amylase; RIKEN cDNA 1810008N23 gene
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
AMY2B (amylase alpha 2B) HGNC
Ensembl, HGNC, HomoloGene, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Canis lupus familiaris (dog):
LOC479922 (pancreatic alpha-amylase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
AMY2 (amylase, alpha 2B (pancreatic)) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
AMY1A (amylase alpha 1A) HGNC
HGNC, Inparanoid, OrthoDB, Panther, Treefam
Homo sapiens (human):
AMY1C (amylase alpha 1C) HGNC
HGNC, OrthoDB, OrthoMCL, Treefam
Homo sapiens (human):
AMY1B (amylase alpha 1B) HGNC
HGNC, OrthoDB, OrthoMCL, Treefam
Homo sapiens (human):
AMY2A (amylase alpha 2A) HGNC
HGNC, OrthoDB, Panther, Treefam
Alliance orthologs 3
Homo sapiens (human):
AMY2A (amylase alpha 2A)
Alliance
DIOPT (Ensembl Compara, HGNC, OMA, OrthoFinder, PANTHER, TreeFam)
Homo sapiens (human):
AMY2B (amylase alpha 2B)
Alliance
DIOPT (Ensembl Compara, HGNC, OMA, OrthoFinder, PANTHER, TreeFam)
Homo sapiens (human):
AMY1C (amylase alpha 1C)
Alliance
DIOPT (Ensembl Compara, HGNC, OMA, OrthoFinder, TreeFam)
Homo sapiens (human):
AMY1B (amylase alpha 1B)
Alliance
DIOPT (Ensembl Compara, HGNC, OMA, OrthoFinder, TreeFam)
Homo sapiens (human):
AMY1A (amylase alpha 1A)
Alliance
DIOPT (Ensembl Compara, HGNC, OMA, OrthoFinder, PANTHER, TreeFam)
Rattus norvegicus (Norway rat):
LOC103689940 (pancreatic alpha-amylase-like)
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder)
Danio rerio (zebrafish):
amy2a (amylase alpha 2A (pancreatic))
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, PANTHER, TreeFam)
Drosophila melanogaster (fruit fly):
Amy-d
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, PANTHER, TreeFam)
Drosophila melanogaster (fruit fly):
Amy-p
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, PANTHER, TreeFam)
Caenorhabditis elegans (roundworm):
C50B6.7
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, PANTHER, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 3 113,249,178 - 113,258,699 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 3 113,052,096 - 113,061,617 (-) NCBI GRCm37 mm9 NCBIm37 MGSCv36 3 113,052,096 - 113,061,617 (-) NCBI mm8 Celera 3 119,916,371 - 119,925,418 (-) NCBI Celera Cytogenetic Map 3 F3 NCBI cM Map 3 49.35 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Gene-Chemical Interaction Annotations
17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of AMY2A5 mRNA CTD PMID:17942748 17beta-estradiol increases expression ISO RGD:1319648 6480464 Estradiol results in increased expression of AMY2B mRNA CTD PMID:21632981 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of AMY2 mRNA CTD PMID:19484750 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of AMY2A5 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1319648 6480464 Tetrachlorodibenzodioxin results in decreased expression of AMY2B mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of AMY2A5 mRNA, Tetrachlorodibenzodioxin affects the expression of AMY2B mRNA CTD PMID:21570461 , PMID:26377647 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of AMY2A5 mRNA CTD PMID:17982090 aflatoxin B1 decreases methylation ISO RGD:1319648 6480464 Aflatoxin B1 results in decreased methylation of AMY2B gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:1319648 6480464 Aflatoxin B1 results in decreased expression of AMY2B mRNA CTD PMID:21632981 arsane affects methylation ISO RGD:1319648 6480464 Arsenic affects the methylation of AMY2B gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1319648 6480464 Arsenic affects the methylation of AMY2B gene CTD PMID:25304211 benzo[a]pyrene decreases expression ISO RGD:1319648 6480464 Benzo(a)pyrene results in decreased expression of AMY2B mRNA CTD PMID:20106945 , PMID:21632981 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of AMY2A5 mRNA CTD PMID:25620056 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon results in increased expression of AMY2A5 mRNA CTD PMID:25620056 cyclosporin A decreases expression ISO RGD:1319648 6480464 Cyclosporine results in decreased expression of AMY2B mRNA CTD PMID:25562108 , PMID:27989131 cyclosporin A increases methylation ISO RGD:1319648 6480464 Cyclosporine results in increased methylation of AMY2B promoter CTD PMID:27989131 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of AMY2A5 mRNA CTD PMID:22733784 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of AMY2A5 mRNA CTD PMID:20542052 methylmercury chloride decreases expression ISO RGD:1319648 6480464 methylmercuric chloride results in decreased expression of AMY2B mRNA CTD PMID:28001369 ozone increases expression EXP 6480464 Ozone results in increased expression of AMY2A5 mRNA CTD PMID:21543283 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of AMY2A5 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:1319648 6480464 Acetaminophen results in increased expression of AMY2B mRNA CTD PMID:26690555 perfluorooctane-1-sulfonic acid affects expression EXP 6480464 perfluorooctane sulfonic acid affects the expression of AMY2A5 mRNA CTD PMID:19429403 perfluorooctanoic acid affects expression EXP 6480464 perfluorooctanoic acid affects the expression of AMY2A5 mRNA CTD PMID:19429403 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of AMY2A5 mRNA CTD PMID:23091169 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of AMY2A5 mRNA CTD PMID:17426115 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of AMY2A5 mRNA CTD PMID:23811191 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of AMY2A5 mRNA CTD PMID:22238285 tetrachloromethane multiple interactions EXP 6480464 PLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of AMY2A5 mRNA] CTD PMID:16006527 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of AMY2A5 mRNA CTD PMID:23409001 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of AMY2A5 mRNA CTD PMID:17292431 valproic acid decreases expression ISO RGD:1319648 6480464 Valproic Acid results in decreased expression of AMY2B mRNA CTD PMID:26272509 
Gene-Chemical Interaction Annotations
