Fbxw13 (F-box and WD-40 domain protein 13) - Rat Genome Database

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Gene: Fbxw13 (F-box and WD-40 domain protein 13) Mus musculus
Analyze
Symbol: Fbxw13
Name: F-box and WD-40 domain protein 13
RGD ID: 1618191
MGI Page MGI
Description: Predicted to be active in cytoplasm. Orthologous to human FBXW12 (F-box and WD repeat domain containing 12).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E330017E16; MGC141227; MGC157442
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399109,008,295 - 109,025,043 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9109,008,295 - 109,025,043 (-)EnsemblGRCm39 Ensembl
GRCm389109,179,227 - 109,195,975 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9109,179,227 - 109,195,975 (-)EnsemblGRCm38mm10GRCm38
MGSCv379109,081,741 - 109,098,489 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369109,036,633 - 109,053,381 (-)NCBIMGSCv36mm8
Celera9108,737,972 - 108,754,720 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.63NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15520277   PMID:16141072   PMID:16141073   PMID:21677750   PMID:21873635  


Genomics

Comparative Map Data
Fbxw13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399109,008,295 - 109,025,043 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9109,008,295 - 109,025,043 (-)EnsemblGRCm39 Ensembl
GRCm389109,179,227 - 109,195,975 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9109,179,227 - 109,195,975 (-)EnsemblGRCm38mm10GRCm38
MGSCv379109,081,741 - 109,098,489 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369109,036,633 - 109,053,381 (-)NCBIMGSCv36mm8
Celera9108,737,972 - 108,754,720 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.63NCBI
FBXW12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,372,219 - 48,394,725 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,372,219 - 48,401,259 (+)EnsemblGRCh38hg38GRCh38
GRCh37348,413,709 - 48,436,190 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,388,713 - 48,411,194 (+)NCBINCBI36Build 36hg18NCBI36
Build 34348,388,712 - 48,411,194NCBI
Celera348,364,476 - 48,386,962 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,468,007 - 48,490,493 (+)NCBIHuRef
CHM1_1348,365,990 - 48,388,474 (+)NCBICHM1_1
T2T-CHM13v2.0348,400,304 - 48,422,793 (+)NCBIT2T-CHM13v2.0
Fbxw12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,660,777 - 118,680,565 (-)NCBIGRCr8
mRatBN7.28109,782,315 - 109,802,086 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,786,815 - 109,801,813 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.08117,871,409 - 117,890,944 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,871,442 - 117,890,930 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,223,248 - 117,243,442 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,152,906 - 114,173,805 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18114,174,950 - 114,193,260 (-)NCBI
Celera8109,072,457 - 109,091,905 (-)NCBICelera
Cytogenetic Map8q32NCBI
FBXW12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,342,011 - 48,371,153 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,346,966 - 48,383,322 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,290,904 - 48,318,318 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,375,181 - 49,399,598 (+)NCBIpanpan1.1PanPan1.1panPan2
FBXW12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,696,434 - 40,711,177 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,696,502 - 40,710,720 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2040,610,074 - 40,686,892 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02041,177,976 - 41,255,021 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2041,181,959 - 41,196,209 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12040,418,762 - 40,495,559 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,819,973 - 40,896,728 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02041,100,712 - 41,177,532 (-)NCBIUU_Cfam_GSD_1.0
Fbxw12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,396,384 - 63,415,071 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936529156,881 - 175,568 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXW12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1229,771,420 - 9,795,768 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl229,772,202 - 9,794,123 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041157,298,216 - 157,320,625 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Fbxw13
504 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:534
Count of miRNA genes:378
Interacting mature miRNAs:415
Transcripts:ENSMUST00000061456, ENSMUST00000173549, ENSMUST00000173606
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9100889929124359700Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9101829255124359700Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9101829255124359700Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103118511124359700Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103118511124359700Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103118511124359700Mouse
13515058Adip20d_madiposity 20d (mouse)9108744078118744078Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000061456   ⟹   ENSMUSP00000053786
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9109,008,295 - 109,025,043 (-)Ensembl
GRCm38.p6 Ensembl9109,179,227 - 109,195,975 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199102   ⟹   ENSMUSP00000142352
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9109,010,594 - 109,024,588 (-)Ensembl
GRCm38.p6 Ensembl9109,181,526 - 109,195,520 (-)Ensembl
RefSeq Acc Id: ENSMUST00000199118   ⟹   ENSMUSP00000143174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9109,008,316 - 109,025,030 (-)Ensembl
GRCm38.p6 Ensembl9109,179,248 - 109,195,962 (-)Ensembl
RefSeq Acc Id: NM_177598   ⟹   NP_808266
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399109,008,295 - 109,025,043 (-)NCBI
GRCm389109,179,227 - 109,195,975 (-)NCBI
MGSCv379109,081,741 - 109,098,489 (-)RGD
Celera9108,737,972 - 108,754,720 (-)RGD
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_808266 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI19543 (Get FASTA)   NCBI Sequence Viewer  
  AAI27238 (Get FASTA)   NCBI Sequence Viewer  
  BAC35738 (Get FASTA)   NCBI Sequence Viewer  
  EDL21347 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000053786
  ENSMUSP00000053786.3
  ENSMUSP00000142352.2
  ENSMUSP00000143174.2
Reference Protein Sequences
RefSeq Acc Id: NP_808266   ⟸   NM_177598
- UniProtKB: Q8BI57 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000142352   ⟸   ENSMUST00000199102
RefSeq Acc Id: ENSMUSP00000143174   ⟸   ENSMUST00000199118
RefSeq Acc Id: ENSMUSP00000053786   ⟸   ENSMUST00000061456
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BI57-F1-model_v2 AlphaFold Q8BI57 1-466 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3505590 AgrOrtholog
Ensembl Genes ENSMUSG00000049314 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000061456 ENTREZGENE
  ENSMUST00000061456.8 UniProtKB/TrEMBL
  ENSMUST00000199102.2 UniProtKB/TrEMBL
  ENSMUST00000199118.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
InterPro F-box_dom_cyclin-like UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report mmu:211305 UniProtKB/TrEMBL
MGD MGI:3505590 ENTREZGENE
NCBI Gene 211305 ENTREZGENE
PANTHER EXPRESSED SEQUENCE C85627-RELATED UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 15 UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 15 UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 3 UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
PhenoGen Fbxw13 PhenoGen
PROSITE FBOX UniProtKB/TrEMBL
SMART FBOX UniProtKB/TrEMBL
Superfamily-SCOP F-box_dom_Skp2-like UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt A0A0G2JDF9_MOUSE UniProtKB/TrEMBL
  A0A0G2JFH5_MOUSE UniProtKB/TrEMBL
  A0JP62_MOUSE UniProtKB/TrEMBL
  Q8BI57 ENTREZGENE, UniProtKB/TrEMBL