Or2t43 (olfactory receptor family 2 subfamily T member 43) - Rat Genome Database

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Gene: Or2t43 (olfactory receptor family 2 subfamily T member 43) Mus musculus
Analyze
No known orthologs.
Symbol: Or2t43
Name: olfactory receptor family 2 subfamily T member 43
RGD ID: 1618019
MGI Page MGI
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR2T4 (olfactory receptor family 2 subfamily T member 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GA_x6K02T00261-652-347; GA_x6K02T2NKPP-858022-858862; MOR275; MOR275-1; MOR275-10_p; MOR275-3; olfactory receptor 224; olfactory receptor 224, pseudogene 1; olfactory receptor 327, pseudogene 1; olfactory receptor MOR275-3; Olfr224; Olfr224-ps1; Olfr32; Olfr327-ps1
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,456,682 - 58,461,394 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,456,682 - 58,461,379 (-)EnsemblGRCm39 Ensembl
GRCm381158,565,856 - 58,570,568 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,565,856 - 58,570,553 (-)EnsemblGRCm38mm10GRCm38
MGSCv371158,379,901 - 58,380,845 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361158,382,599 - 58,383,538 (-)NCBIMGSCv36mm8
MGSCv361159,086,569 - 59,087,510 (-)NCBIMGSCv36mm8
Celera1163,311,849 - 63,312,935 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1136.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:14611657   PMID:15081110   PMID:21873635   PMID:32295537  


Genomics

Variants

.
Variants in Or2t43
215 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:294
Count of miRNA genes:97
Interacting mature miRNAs:98
Transcripts:ENSMUST00000081102, ENSMUST00000108822, ENSMUST00000108823
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5406567063319522Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115406567067078411Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
13513917Heal54_mwound healing/ regeneration 54 (mouse)115787291759879610Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115408094165103841Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000081102   ⟹   ENSMUSP00000079881
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,457,225 - 58,458,169 (-)Ensembl
GRCm38.p6 Ensembl1158,566,399 - 58,567,343 (-)Ensembl
Ensembl Acc Id: ENSMUST00000215322   ⟹   ENSMUSP00000150143
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,456,682 - 58,459,993 (-)Ensembl
GRCm38.p6 Ensembl1158,565,856 - 58,569,167 (-)Ensembl
Ensembl Acc Id: ENSMUST00000216758   ⟹   ENSMUSP00000150140
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,456,682 - 58,461,379 (-)Ensembl
GRCm38.p6 Ensembl1158,565,856 - 58,570,553 (-)Ensembl
Ensembl Acc Id: ENSMUST00000217009   ⟹   ENSMUSP00000150268
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,456,682 - 58,459,993 (-)Ensembl
GRCm38.p6 Ensembl1158,565,856 - 58,569,167 (-)Ensembl
RefSeq Acc Id: NM_207695   ⟹   NP_997578
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,456,682 - 58,461,394 (-)NCBI
GRCm381158,565,856 - 58,570,568 (-)NCBI
Celera1163,287,946 - 63,312,935 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_997578 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAS99769 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000079881.5
  ENSMUSP00000150140
  ENSMUSP00000150140.2
  ENSMUSP00000150143.2
  ENSMUSP00000150268.2
RefSeq Acc Id: NP_997578   ⟸   NM_207695
- UniProtKB: M9MMJ7 (UniProtKB/TrEMBL),   Q7TRY9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000150268   ⟸   ENSMUST00000217009
Ensembl Acc Id: ENSMUSP00000150140   ⟸   ENSMUST00000216758
Ensembl Acc Id: ENSMUSP00000079881   ⟸   ENSMUST00000081102
Ensembl Acc Id: ENSMUSP00000150143   ⟸   ENSMUST00000215322
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M9MMJ7-F1-model_v2 AlphaFold M9MMJ7 1-314 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030058 AgrOrtholog
Ensembl Genes ENSMUSG00000059279 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000081102.5 UniProtKB/TrEMBL
  ENSMUST00000215322.2 UniProtKB/TrEMBL
  ENSMUST00000216758 ENTREZGENE
  ENSMUST00000216758.2 UniProtKB/TrEMBL
  ENSMUST00000217009.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258198 UniProtKB/TrEMBL
MGD MGI:3030058 ENTREZGENE
NCBI Gene Or2t43 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 2T29-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2t43 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt M9MMJ7 ENTREZGENE, UniProtKB/TrEMBL
  Q6W078_MOUSE UniProtKB/TrEMBL
  Q7TRY9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-10-29 Or2t43  olfactory receptor family 2 subfamily T member 43  Olfr224  olfactory receptor 224  Symbol and/or name change 5135510 APPROVED
2024-10-29 Olfr224  olfactory receptor 224  Or2t43  olfactory receptor family 2 subfamily T member 43  Symbol and/or name change 5135510 APPROVED
2024-08-21 Or2t43  olfactory receptor family 2 subfamily T member 43  Olfr224  olfactory receptor 224  Symbol and/or name change 5135510 APPROVED
2024-08-21 Olfr224  olfactory receptor 224  Or2t43  olfactory receptor family 2 subfamily T member 43  Symbol and/or name change 5135510 APPROVED
2022-05-24 Or2t43  olfactory receptor family 2 subfamily T member 43  Olfr224  olfactory receptor 224  Symbol and/or name change 5135510 APPROVED
2015-05-05 Olfr224  olfactory receptor 224  Olfr224  olfactory receptor 224  Data merged from RGD:1613228 737654 PROVISIONAL
2014-09-17 Olfr224  olfactory receptor 224  Olfr327-ps1  olfactory receptor 327, pseudogene 1  Symbol and/or name change 5135510 APPROVED