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Gene: Tubb1 (tubulin, beta 1 class VI) Mus musculus
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Symbol: Tubb1
Name: tubulin, beta 1 class VI
Description: A structural constituent of cytoskeleton. Involved in spindle assembly. Localizes to the microtubule. Human ortholog(s) of this gene implicated in autosomal dominant macrothrombocytopenia TUBB1-related. Is expressed in dorsal root ganglion; liver; and spinal cord. Orthologous to human TUBB1 (tubulin beta 1 class VI); PARTICIPATES IN docetaxel pharmacodynamics pathway; tyrosinemia type III pathway; vinblastine pharmacodynamics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; sodium fluoride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810484G07Rik; M(beta)1; tubulin beta-1 chain; tubulin, beta 1
Orthologs:
Homo sapiens (human) : TUBB1 (tubulin beta 1 class VI)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tubb1 (tubulin, beta 1 class VI)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tubb1 (tubulin beta 1 class VI)
Pan paniscus (bonobo/pygmy chimpanzee) : TUBB1 (tubulin beta 1 class VI)
Canis lupus familiaris (dog) : TUBB1 (tubulin beta 1 class VI)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tubb1 (tubulin beta 1 class VI)
Sus scrofa (pig) : TUBB1 (tubulin beta 1 class VI)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382174,450,595 - 174,458,380 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372174,276,196 - 174,283,383 (+)NCBIGRCm37mm9NCBIm37
MGSCv362174,093,634 - 174,101,450 (+)NCBImm8
Celera2180,411,327 - 180,419,126 (+)NCBICelera
Cytogenetic Map2 H4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Tubb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1617888
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.