Faiml (Fas apoptotic inhibitory molecule like) - Rat Genome Database
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Gene: Faiml (Fas apoptotic inhibitory molecule like) Mus musculus
Analyze
No known orthologs.
Symbol: Faiml
Name: Fas apoptotic inhibitory molecule like
RGD ID: 1617844
MGI Page MGI
Description: Predicted to be involved in I-kappaB kinase/NF-kappaB signaling; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of neurogenesis. Orthologous to human FAIM (Fas apoptotic inhibitory molecule).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EG623459; fas apoptotic inhibitory molecule 1-like; Gm6432
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39999,111,429 - 99,119,292 (-)NCBIGRCm39mm39
GRCm38999,229,376 - 99,237,239 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl999,229,376 - 99,237,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv37999,129,795 - 99,137,658 (-)NCBIGRCm37mm9NCBIm37
MGSCv36999,038,728 - 99,046,682 (-)NCBImm8
Celera998,769,304 - 98,777,191 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21873635   PMID:24071998  


Genomics


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95212317899910428Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966207024100207122Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967124167101124167Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968897510102897652Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968897510102897652Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969239845103239920Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969546513103546645Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976117105101528921Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:69
Interacting mature miRNAs:69
Transcripts:ENSMUST00000178051
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000178051   ⟹   ENSMUSP00000137541
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl999,229,376 - 99,237,239 (-)Ensembl
RefSeq Acc Id: ENSMUST00000188555   ⟹   ENSMUSP00000139801
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl999,229,468 - 99,236,370 (-)Ensembl
RefSeq Acc Id: NM_001244762   ⟹   NP_001231691
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39999,111,429 - 99,119,292 (-)NCBI
GRCm38999,229,376 - 99,237,239 (-)ENTREZGENE
Celera998,769,304 - 98,777,191 (-)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001231691 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL20999 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001231691   ⟸   NM_001244762
- UniProtKB: J3QPY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000137541   ⟸   ENSMUST00000178051
RefSeq Acc Id: ENSMUSP00000139801   ⟸   ENSMUST00000188555

Promoters
RGD ID:8670552
Promoter ID:EPDNEW_M13307
Type:multiple initiation site
Name:Faiml_1
Description:Mus musculus Fas apoptotic inhibitory molecule like , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38999,237,239 - 99,237,299EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3647754 AgrOrtholog
Ensembl Genes ENSMUSG00000096316 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000137541 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000139801 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000178051 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000188555 UniProtKB/TrEMBL
Gene3D-CATH 2.40.128.180 UniProtKB/TrEMBL
InterPro FAIM UniProtKB/TrEMBL
  FAIM1_dom_sf UniProtKB/TrEMBL
KEGG Report mmu:623459 UniProtKB/TrEMBL
MGD MGI:3647754 ENTREZGENE
NCBI Gene 623459 ENTREZGENE
PANTHER PTHR13088 UniProtKB/TrEMBL
Pfam FAIM1 UniProtKB/TrEMBL
PhenoGen Faiml PhenoGen
UniGene Mm.260891 ENTREZGENE
UniProt J3QPY3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-30 Faiml  Fas apoptotic inhibitory molecule like  Gm6432  predicted gene 6432  Symbol and/or name change 5135510 APPROVED