Gene: Ncr3-ps (natural cytotoxicity triggering receptor 3, pseudogene) Mus musculus
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Symbol:
Ncr3-ps
Name:
natural cytotoxicity triggering receptor 3, pseudogene
Description:
Human ortholog(s) of this gene implicated in malaria. Orthologous to human NCR3 (natural cytotoxicity triggering receptor 3); INTERACTS WITH (+)-catechin (ortholog); all-trans-retinoic acid (ortholog); ammonium chloride (ortholog).
Type:
pseudo
RefSeq Status:
INFERRED
Also known as:
1C7; EG667612; Gm8726; leukocyte specific transcript 1; Lst1; Ly117; lymphocyte antigen 117; natural cytotoxicity triggering receptor 3; Ncr3
Orthologs:
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 17 35,180,536 - 35,184,809 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 17 35,317,481 - 35,321,754 (+) NCBI GRCm37 mm9 NCBIm37 MGSCv36 17 34,788,588 - 34,792,861 (+) NCBI mm8 Celera 17 38,277,471 - 38,281,742 (+) NCBI Celera Cytogenetic Map 17 B1 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - CTD
malaria ISO RGD:1353948 11554173 CTD Direct Evidence: marker/mechanism CTD
Imported Annotations - OMIM
malaria susceptibility ISO RGD:1353948 7240710 OMIM
Gene-Chemical Interaction Annotations
(+)-catechin multiple interactions ISO RGD:1353948 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of NCR3 mRNA CTD PMID:24763279 all-trans-retinoic acid decreases expression ISO RGD:1353948 6480464 Tretinoin results in decreased expression of NCR3 protein CTD PMID:17107666 ammonium chloride affects expression ISO RGD:727881 6480464 Ammonium Chloride affects the expression of NCR3 mRNA CTD PMID:16483693 bisphenol A decreases expression ISO RGD:727881 6480464 bisphenol A results in decreased expression of NCR3 mRNA CTD PMID:25181051 bisphenol A affects methylation ISO RGD:727881 6480464 bisphenol A affects the methylation of NCR3 promoter CTD PMID:27415467 cadmium dichloride decreases methylation ISO RGD:727881 6480464 Cadmium Chloride results in decreased methylation of NCR3 promoter CTD PMID:22457795 cobalt dichloride decreases expression ISO RGD:727881 6480464 cobaltous chloride results in decreased expression of NCR3 mRNA CTD PMID:24386269 copper atom increases expression ISO RGD:727881 6480464 Copper deficiency results in increased expression of NCR3 mRNA CTD PMID:26033743 copper(0) increases expression ISO RGD:727881 6480464 Copper deficiency results in increased expression of NCR3 mRNA CTD PMID:26033743 cyclosporin A increases expression ISO RGD:1353948 6480464 Cyclosporine results in increased expression of NCR3 CTD PMID:20736080 endosulfan increases expression ISO RGD:727881 6480464 Endosulfan results in increased expression of NCR3 mRNA CTD PMID:29391264 mycophenolic acid decreases expression ISO RGD:1353948 6480464 Mycophenolic Acid results in decreased expression of NCR3 CTD PMID:20736080 paracetamol increases expression ISO RGD:1353948 6480464 Acetaminophen results in increased expression of NCR3 mRNA CTD PMID:26690555 PD 0325901 multiple interactions ISO RGD:1353948 6480464 PD 0325901 inhibits the reaction [IL15 protein results in increased expression of NCR3 protein], PD 0325901 inhibits the reaction [IL2 protein results in increased expression of NCR3 protein] CTD PMID:27563819 tacrolimus hydrate increases expression ISO RGD:1353948 6480464 Tacrolimus results in increased expression of NCR3 CTD PMID:20736080 zinc atom increases expression ISO RGD:1353948 6480464 Zinc deficiency results in increased expression of NCR3 mRNA CTD PMID:18356318 zinc(0) increases expression ISO RGD:1353948 6480464 Zinc deficiency results in increased expression of NCR3 mRNA CTD PMID:18356318
10412276 Leci2_m leukocyte endothelial cell interactions 2 (mouse) Not determined 17 3127913 37128037 Mouse 1300890 Bhr3_m bronchial hyperresponsiveness 3 (mouse) Not determined 17 3924615 48559063 Mouse 4141215 Mnic1_m macronutrient intake, carbohydrate 1 (mouse) Not determined 4804477 45359340 Mouse 1300706 Alan1_m alloantigen response 1 (mouse) Not determined 17 4804477 46158776 Mouse 1357789 Kdnw3_m kidney weight 3 (mouse) Not determined 17 4804477 47574740 Mouse 4141272 Tfv1_m total food volume 1 (mouse) Not determined 4804477 65330362 Mouse 10043949 Pbft7_m percent body fat 7 (mouse) Not determined 17 6674962 40674962 Mouse 1301935 Skull24_m skull morphology 24 (mouse) Not determined 17 8365940 42366175 Mouse 1300787 Cd8mts5_m CD8 memory T cell subset 5 (mouse) Not determined 17 8365940 42366175 Mouse 1301338 Lmr1_m leishmaniasis resistance 1 (mouse) Not determined 17 9862411 86688972 Mouse 1302028 Asbb3_m autoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse) Not determined 17 10659145 44659245 Mouse 4142342 Lfnq4_m lung function QTL 4 (mouse) Not determined 10987597 39053168 Mouse 4141067 Hbnr2_m Heligmosomoides bakeri nematode resistance 2 (mouse) Not determined 11666997 45667145 Mouse 14747010 Mancz14_m mandible centroid size 14 (mouse) 17 11779210 45779210 Mouse 4142150 Stheal11_m soft tissue heal 11 (mouse) Not determined 17 12067324 83054339 Mouse 12904946 Tammq8_m tibialis anterior muscle mass QTL 8 (mouse) 17 12232813 46232813 Mouse 13524847 Asrq8a_m acoustic startle response 8a (mouse) 17 12427987 46427987 Mouse 11081168 Tir7_m trypanosome infection response 7 (mouse) 17 13904398 47904522 Mouse 1300914 Pcir4_m periosteal circumference 4 (mouse) Not determined 17 14842678 48842786 Mouse 1558886 Lgth9_m body length 9 (mouse) Not determined 17 14842678 48842786 Mouse 1302070 Tbbmd7_m total body bone mineral density 7 (mouse) Not determined 17 14842678 48842786 Mouse 1300995 Fembrs4_m femur breaking strength 4 (mouse) Not determined 17 14842678 48842786 Mouse 1302140 Wta4_m weight adult 4 (mouse) Not determined 17 16600747 50600869 Mouse 1302152 Skull25_m skull morphology 25 (mouse) Not determined 17 16600747 50600869 Mouse 1301505 Tir1_m trypanosome infection response 1 (mouse) Not determined 17 16600747 50600869 Mouse 10412083 Sm2_m susceptibility to Schistosoma mansoni infection 2 (mouse) Not determined 17 16810969 50811104 Mouse 1302042 Acsns3_m Angiostrongylus costaricensis nematode susceptibility 3 (mouse) Not determined 17 17243234 51243371 Mouse 1300535 Char3_m P. chabaudi malaria resistance QTL 3 (mouse) Not determined 17 17243234 51243371 Mouse 10412214 Sxbq3_m SGC/Knj cross B6 QTL 3 (mouse) Not determined 17 17243234 51243371 Mouse 13452396 Leusq3_m leucocytosis susceptibility QTL 3 (mouse) 17 17243234 51243371 Mouse 13452399 Leusq6_m leucocytosis susceptibility QTL 6 (mouse) 17 17243234 51243371 Mouse 1301840 Ssial4_m susceptibility to sialadenitiss 4 (mouse) Not determined 17 17956436 51959238 Mouse 1301331 Lbw1_m lupus NZB x NZW 1 (mouse) Not determined 17 18199381 52202007 Mouse 1301056 Pas2_m pulmonary adenoma susceptibility 2 (mouse) Not determined 17 18203165 52205351 Mouse 15039354 Nmrs36_m NAFLD-associated magnetic resonance shift 36 (mouse) 17 18834133 52834133 Mouse 1301454 Eae5_m susceptibility to experimental allergic encephalomyelitis 5 (mouse) Not determined 17 24301859 58301973 Mouse 10412198 Sst5_m susceptibility to tuberculosis 5 (mouse) Not determined 17 24857609 55405969 Mouse 10412196 Bbaa28_m B.burgdorferi-associated arthritis 28 (mouse) Not determined 17 25365940 43665344 Mouse 10412204 Bbaa29_m B.burgdorferi-associated arthritis 29 (mouse) Not determined 17 25740294 59740461 Mouse 1558758 Kcal2_m kilocalorie 2 (mouse) Not determined 17 26182038 52604676 Mouse 1300602 Eye2_m eye weight 2 (mouse) Not determined 17 26286363 40794146 Mouse 1302005 Loco2_m locomotor activity 2 (mouse) Not determined 17 26574081 60574223 Mouse 11075105 Modc1_m modifier of Odc1 (mouse) 17 27496818 45311728 Mouse 15039348 Nmrs37_m NAFLD-associated magnetic resonance shift 37 (mouse) 17 27504322 61504322 Mouse 10045977 Tir9_m trypanosome infection response 9 (mouse) Not determined 17 27659145 43574223 Mouse 1300703 Uvbi2_m UVB induced immunosuppression 2 (mouse) Not determined 17 28311480 62311728 Mouse 1300589 Myaa2_m modifier of Yaa 2 (mouse) Not determined 17 29821629 63821740 Mouse 4140955 Plgr1_m plague resistance locus 1 (mouse) Not determined 30722575 64722705 Mouse 4141357 Mrdq1_m modifier of retinal degeneration QTL 1 (mouse) Not determined 30768929 47728778 Mouse 1300692 Blmpf1_m bleomycin-induced pulmonary fibrosis 1 (mouse) Not determined 17 31842678 37333884 Mouse 1302189 Dps3_m delta power in slow-wave sleep 3 (mouse) Not determined 17 33600747 35939288 Mouse 1300885 Mbis4_m Mycobacterium bovis-induced systemic lupus erythematosus 4 (mouse) Not determined 17 34956841 69858931 Mouse
Predicted Target Of
Count of predictions: 187 Count of miRNA genes: 179 Interacting mature miRNAs: 185 Transcripts: ENSMUST00000134687 Prediction methods: Microtar, Miranda, Rnahybrid Result types: miRGate_prediction