Agl (amylo-1,6-glucosidase, 4-alpha-glucanotransferase) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Agl (amylo-1,6-glucosidase, 4-alpha-glucanotransferase) Mus musculus
Analyze
Symbol: Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
RGD ID: 1617454
MGI Page MGI
Description: Enables several functions, including 4-alpha-glucanotransferase activity; amylo-alpha-1,6-glucosidase activity; and polyubiquitin modification-dependent protein binding activity. Involved in glycogen catabolic process. Acts upstream of or within glycogen metabolic process. Located in cytoplasm; inclusion body; and nucleus. Is active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; heart; musculature; and sensory organ. Used to study glycogen storage disease III. Human ortholog(s) of this gene implicated in glycogen storage disease III. Orthologous to human AGL (amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110061O17Rik; 9430004C13Rik; 9630046L06Rik; AI850929; C77197; glycogen debranching enzyme
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393116,533,648 - 116,601,815 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3116,533,648 - 116,601,815 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383116,739,999 - 116,808,166 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3116,739,999 - 116,808,166 (-)Ensemblmm10GRCm38
MGSCv373116,442,917 - 116,511,084 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363116,732,003 - 116,800,170 (-)NCBIMGSCv36mm8
Celera3123,163,575 - 123,226,478 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map350.47NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
chlorpyrifos  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
fenvalerate  (ISO)
folic acid  (EXP)
glucose  (ISO)
glycogen  (ISO)
ivermectin  (ISO)
Licochalcone B  (ISO)
methimazole  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
motexafin gadolinium  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
parathion  (EXP)
pentachlorophenol  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
potassium dichromate  (EXP)
propiconazole  (EXP)
quercetin  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
trovafloxacin  (EXP)
valproic acid  (EXP,ISO)
zinc acetate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IDA,ISO)
cytosol  (IDA,IMP)
inclusion body  (IDA)
nucleus  (IDA)
sarcoplasmic reticulum  (ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. The genetic association database. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
2. Inhibition of glycogenolysis by a glucose analogue in the working rat heart. Depre C and Hue L, J Mol Cell Cardiol. 1997 Aug;29(8):2253-9.
3. Glycogen debranching enzyme is associated with rat skeletal muscle sarcoplasmic reticulum. Lees SJ, etal., Acta Physiol Scand. 2004 Jun;181(2):239-45.
4. Carbohydrate metabolism in the chronically uremic rat. Mannan A, etal., Clin Biochem. 1975 Jun;8(3):194-8.
5. N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly improves postischemic left ventricular dysfunction. Nishida Y, etal., Heart Vessels. 2000;15(6):268-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Glycogen-binding protein components of rat tissues. Satoh K and Sato K, Biochem Biophys Res Commun. 1980 Sep 16;96(1):28-33.
13. Mutations in exon 3 of the glycogen debranching enzyme gene are associated with glycogen storage disease type III that is differentially expressed in liver and muscle. Shen J, etal., J Clin Invest. 1996 Jul 15;98(2):352-7.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11785984   PMID:12466851   PMID:12477932   PMID:14610273   PMID:14681479  
PMID:15886229   PMID:16141072   PMID:16141073   PMID:16919269   PMID:17908927   PMID:17937387   PMID:18973680   PMID:21267068   PMID:21677750   PMID:21873635   PMID:24194600   PMID:24613482  
PMID:25092169   PMID:25849460   PMID:27215380   PMID:27626380   PMID:29093530   PMID:29396266   PMID:29784585   PMID:30076962   PMID:30403777   PMID:32637453   PMID:32798765   PMID:34043942  
PMID:35449600   PMID:38015640   PMID:38355793   PMID:40064848  


Genomics

Comparative Map Data
Agl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393116,533,648 - 116,601,815 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3116,533,648 - 116,601,815 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383116,739,999 - 116,808,166 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3116,739,999 - 116,808,166 (-)Ensemblmm10GRCm38
MGSCv373116,442,917 - 116,511,084 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363116,732,003 - 116,800,170 (-)NCBIMGSCv36mm8
Celera3123,163,575 - 123,226,478 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map350.47NCBI
AGL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38199,849,258 - 99,924,023 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl199,850,361 - 99,924,023 (+)Ensemblhg38GRCh38
GRCh371100,315,917 - 100,389,576 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361100,088,228 - 100,162,167 (+)NCBIBuild 36Build 36hg18NCBI36
Celera198,570,515 - 98,644,447 (+)NCBICelera
Cytogenetic Map1p21.2NCBI
HuRef198,438,182 - 98,512,138 (+)NCBIHuRef
CHM1_11100,431,893 - 100,506,067 (+)NCBICHM1_1
T2T-CHM13v2.0199,697,491 - 99,772,284 (+)NCBIT2T-CHM13v2.0
Agl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82207,389,949 - 207,445,959 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2207,389,949 - 207,445,724 (-)EnsemblGRCr8
mRatBN7.22204,705,053 - 204,760,966 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2204,705,053 - 204,760,828 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2212,360,352 - 212,416,298 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02210,276,718 - 210,333,402 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02205,093,802 - 205,150,486 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02219,788,234 - 219,843,189 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2219,788,234 - 219,842,986 (-)Ensemblrn6Rnor6.0
Rnor_5.02237,375,913 - 237,430,811 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42212,985,676 - 213,041,451 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2197,196,717 - 197,252,494 (-)NCBICelera
RGSC_v3.12212,950,852 - 213,004,133 (-)NCBI
Cytogenetic Map2q42NCBI
Agl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554354,621,991 - 4,688,139 (+)Ensembl
ChiLan1.0NW_0049554354,622,142 - 4,684,439 (+)NCBIChiLan1.0ChiLan1.0
AGL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21127,105,703 - 127,181,631 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11126,260,783 - 126,336,647 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01102,506,234 - 102,580,183 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11101,225,646 - 101,299,511 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1101,226,120 - 101,299,511 (+)EnsemblpanPan2panpan1.1
AGL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1650,039,661 - 50,112,543 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl650,041,947 - 50,112,279 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha652,720,444 - 52,790,584 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0650,395,404 - 50,468,323 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl650,397,314 - 50,468,172 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1650,089,271 - 50,159,524 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0650,068,211 - 50,138,107 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0650,499,977 - 50,570,258 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Agl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058109,668,098 - 109,703,925 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493722423,225 - 32,639 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4118,177,377 - 118,269,101 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.14118,186,031 - 118,269,106 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24129,759,895 - 129,831,601 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12033,422,807 - 33,491,335 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2033,422,790 - 33,490,016 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603824,565,816 - 24,633,799 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248572,629,313 - 2,728,196 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248572,629,158 - 2,730,764 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Agl
3999 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:4607
Count of miRNA genes:982
Interacting mature miRNAs:1456
Transcripts:ENSMUST00000040603, ENSMUST00000159670, ENSMUST00000159742, ENSMUST00000159995, ENSMUST00000160484, ENSMUST00000161336, ENSMUST00000162040, ENSMUST00000162792
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
12910796Pwbwq6_mpost-weaning body weight QTL 6 (mouse)3110084357135715812Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
12910793Pwbwq7_mpost-weaning body weight QTL 7 (mouse)3110084357135715812Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
11533920Mvb3_mmodifier of vibrator 3 (mouse)398635284132635383Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
1301381Bomb1_mbone marrow pre-B 1 (mouse)Not determined3111133243145133417Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
1300619Cdcs1_mcytokine deficiency colitis susceptibility 1 (mouse)Not determined3109834882143835005Mouse
26884419Bzwq6_mbi-zygomatic width QTL 6, 10 week (mouse)3100607316137205761Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
12910815Ogrq1_moverall growth rate QTL 1 (mouse)3110084357135715812Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
12792984Modn1_mmodifier of Dstn neovascularization 1 (mouse)398635284132635383Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
1302093Orgwq5_morgan weight QTL 5 (mouse)Not determined3107376936147304689Mouse
10043955Wt10q4_mbody weight, 10 weeks, QTL 4 (mouse)Not determined398624041132624197Mouse
8655599Cia5c_mcollagen induced arthritis QTL 5c (mouse)Not determined3107376936125316237Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
1302114Tbs1_mtuberculosis severity 1 (mouse)Not determined398924105132924250Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392251533126251650Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
1301805Mors2_mmodifier of obesity related sterility 2 (mouse)Not determined3103482659137482783Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse
1301100Bdt2_mbone density traits 2 (mouse)Not determined3114736617148736784Mouse

Markers in Region
D3Mit314  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383116,782,995 - 116,783,194UniSTSGRCm38
MGSCv373116,485,913 - 116,486,112UniSTSGRCm37
Celera3123,201,450 - 123,201,650UniSTS
Cytogenetic Map3G1UniSTS
cM Map355.0UniSTS
Whitehead Genetic340.4UniSTS
Whitehead_YAC3 UniSTS
RH126117  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383116,744,587 - 116,744,813UniSTSGRCm38
MGSCv373116,447,505 - 116,447,731UniSTSGRCm37
Celera3123,168,163 - 123,168,389UniSTS
Cytogenetic Map3G1UniSTS
Whitehead/MRC_RH31353.99UniSTS
AI850929  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383116,743,162 - 116,743,297UniSTSGRCm38
MGSCv373116,446,080 - 116,446,215UniSTSGRCm37
Celera3123,166,737 - 123,166,872UniSTS
Cytogenetic Map3G1UniSTS
Whitehead/MRC_RH31355.17UniSTS
Agl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383116,781,024 - 116,781,100UniSTSGRCm38
MGSCv373116,483,942 - 116,484,018UniSTSGRCm37
Celera3123,199,479 - 123,199,555UniSTS
Cytogenetic Map3G1UniSTS
cM Map3 UniSTS
D11Bhm20  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map19D1UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map12D1UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map4E1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map16C1.1UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map1C1.3UniSTS
Cytogenetic Map13D2UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A2UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map16C4UniSTS
Cytogenetic Map3G1UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map7B1-B2UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic Map11B1.1UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXC-DUniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map11A3.2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map19BUniSTS
cM Map1144.15UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000040603   ⟹   ENSMUSP00000044012
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3116,533,648 - 116,601,815 (-)Ensembl
GRCm38.p6 Ensembl3116,739,999 - 116,808,166 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159670   ⟹   ENSMUSP00000124840
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3116,585,777 - 116,601,500 (-)Ensembl
GRCm38.p6 Ensembl3116,792,128 - 116,807,851 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159742   ⟹   ENSMUSP00000143582
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3116,548,184 - 116,601,778 (-)Ensembl
GRCm38.p6 Ensembl3116,754,535 - 116,808,129 (-)Ensembl
Ensembl Acc Id: ENSMUST00000159995   ⟹   ENSMUSP00000125246
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3116,573,662 - 116,575,399 (-)Ensembl
GRCm38.p6 Ensembl3116,780,013 - 116,781,750 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160484   ⟹   ENSMUSP00000123985
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3116,536,700 - 116,574,899 (-)Ensembl
GRCm38.p6 Ensembl3116,743,051 - 116,781,250 (-)Ensembl
Ensembl Acc Id: ENSMUST00000161336   ⟹   ENSMUSP00000123877
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3116,541,731 - 116,601,691 (-)Ensembl
GRCm38.p6 Ensembl3116,748,082 - 116,808,042 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162040
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3116,584,429 - 116,601,680 (-)Ensembl
GRCm38.p6 Ensembl3116,790,780 - 116,808,031 (-)Ensembl
Ensembl Acc Id: ENSMUST00000162792   ⟹   ENSMUSP00000124149
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3116,536,156 - 116,601,066 (-)Ensembl
GRCm38.p6 Ensembl3116,742,507 - 116,807,417 (-)Ensembl
RefSeq Acc Id: NM_001081326   ⟹   NP_001074795
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393116,533,648 - 116,601,815 (-)NCBI
GRCm383116,739,999 - 116,808,166 (-)ENTREZGENE
MGSCv373116,442,917 - 116,511,084 (-)RGD
Celera3123,163,575 - 123,226,478 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001362367   ⟹   NP_001349296
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393116,548,184 - 116,601,815 (-)NCBI
GRCm383116,754,535 - 116,808,166 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001074795   ⟸   NM_001081326
- Peptide Label: isoform 1
- UniProtKB: F8VPN4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001349296   ⟸   NM_001362367
- Peptide Label: isoform 2
- UniProtKB: A0A0G2JGI9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000125246   ⟸   ENSMUST00000159995
Ensembl Acc Id: ENSMUSP00000124840   ⟸   ENSMUST00000159670
Ensembl Acc Id: ENSMUSP00000143582   ⟸   ENSMUST00000159742
Ensembl Acc Id: ENSMUSP00000044012   ⟸   ENSMUST00000040603
Ensembl Acc Id: ENSMUSP00000123985   ⟸   ENSMUST00000160484
Ensembl Acc Id: ENSMUSP00000124149   ⟸   ENSMUST00000162792
Ensembl Acc Id: ENSMUSP00000123877   ⟸   ENSMUST00000161336
Protein Domains
Eukaryotic glycogen debranching enzyme N-terminal   Glycogen debranching enzyme C-terminal   Glycogen debranching enzyme central   Glycogen debranching enzyme glucanotransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F8VPN4-F1-model_v2 AlphaFold F8VPN4 1-1532 view protein structure

Promoters
RGD ID:6833356
Promoter ID:MM_KWN:35904
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:UC008RCR.1,   UC008RCT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363116,485,221 - 116,485,721 (-)MPROMDB
RGD ID:6833357
Promoter ID:MM_KWN:35905
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001081326,   UC008RCS.1,   UC008RCU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363116,510,906 - 116,512,032 (-)MPROMDB
RGD ID:6882186
Promoter ID:EPDNEW_M4544
Type:initiation region
Name:Agl_1
Description:Mus musculus amylo-1,6-glucosidase, 4-alpha-glucanotransferase, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4545  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383116,808,099 - 116,808,159EPDNEW
RGD ID:6882188
Promoter ID:EPDNEW_M4545
Type:multiple initiation site
Name:Agl_2
Description:Mus musculus amylo-1,6-glucosidase, 4-alpha-glucanotransferase, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4544  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383116,808,244 - 116,808,304EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1924809 AgrOrtholog
Ensembl Genes ENSMUSG00000033400 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000040603 ENTREZGENE
  ENSMUST00000040603.14 UniProtKB/TrEMBL
  ENSMUST00000159670.3 UniProtKB/TrEMBL
  ENSMUST00000159742 ENTREZGENE
  ENSMUST00000159742.8 UniProtKB/TrEMBL
  ENSMUST00000159995.2 UniProtKB/TrEMBL
  ENSMUST00000160484.6 UniProtKB/TrEMBL
  ENSMUST00000161336.8 UniProtKB/TrEMBL
  ENSMUST00000162792.8 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.10 UniProtKB/TrEMBL
  Glycosidases UniProtKB/TrEMBL
InterPro 6-hairpin_glycosidase-like UniProtKB/TrEMBL
  6hp_glycosidase-like_sf UniProtKB/TrEMBL
  AGL_central UniProtKB/TrEMBL
  AGL_euk_N UniProtKB/TrEMBL
  AGL_glucanoTrfase UniProtKB/TrEMBL
  GDE_C UniProtKB/TrEMBL
  GDE_C UniProtKB/TrEMBL
  Glycogen_debranch_met UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
KEGG Report mmu:77559 UniProtKB/TrEMBL
MGD MGI:1924809 ENTREZGENE
NCBI Gene 77559 ENTREZGENE
PANTHER GDE_C UniProtKB/TrEMBL
  GLYCOGEN DEBRANCHING ENZYME UniProtKB/TrEMBL
Pfam GDE_C UniProtKB/TrEMBL
  hDGE_amylase UniProtKB/TrEMBL
  hGDE_central UniProtKB/TrEMBL
  hGDE_N UniProtKB/TrEMBL
PhenoGen Agl PhenoGen
Superfamily-SCOP Glyco_hydro_cat UniProtKB/TrEMBL
  Glyco_trans_6hp UniProtKB/TrEMBL
UniProt A0A0G2JGI9 ENTREZGENE, UniProtKB/TrEMBL
  E0CX86_MOUSE UniProtKB/TrEMBL
  E0CYU6_MOUSE UniProtKB/TrEMBL
  F6XXE6_MOUSE UniProtKB/TrEMBL
  F7CSZ6_MOUSE UniProtKB/TrEMBL
  F8VPN4 ENTREZGENE, UniProtKB/TrEMBL
  Q8CE68_MOUSE UniProtKB/TrEMBL