Hbq1a (hemoglobin, theta 1A) - Rat Genome Database

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Gene: Hbq1a (hemoglobin, theta 1A) Mus musculus
Analyze
No known orthologs.
Symbol: Hbq1a
Name: hemoglobin, theta 1A
RGD ID: 1617381
MGI Page MGI
Description: Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Orthologous to human HBQ1 (hemoglobin subunit theta 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: A230090E05Rik; Gm876; Hbq1; Hbq1 3'-theta; Hbqt2; hemoglobin, theta 1; hemoglobin, theta T2; RP23-375M9.6
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,250,069 - 32,250,873 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,250,069 - 32,250,873 (+)EnsemblGRCm39 Ensembl
GRCm381132,300,069 - 32,300,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,300,069 - 32,300,873 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,200,069 - 32,200,873 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,200,069 - 32,200,873 (+)NCBIMGSCv36mm8
Celera1134,717,450 - 34,718,254 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11157800   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15215894   PMID:16141072   PMID:16141073   PMID:17218265   PMID:18245844  
PMID:21267068   PMID:21873635   PMID:22056776   PMID:24194600   PMID:34321999  


Genomics

Variants

.
Variants in Hbq1a
16 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:233
Count of miRNA genes:222
Interacting mature miRNAs:229
Transcripts:ENSMUST00000020535
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
10412216Eae44_mexperimental allergic encephalomyelitis susceptibility 44 (mouse)Not determined111226863739950840Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1300607Tnbs2_mtri-nitrobenzene sulfonic acid susceptible 2 (mouse)Not determined112489805235126680Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1301814Bbaa7_mB.burgdorferi-associated arthritis 7 (mouse)Not determined112601178044264695Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
25394552Skmw69_mskeletal muscle weight 69, TA (mouse)112969902932329535Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
25394550Skmw71_mskeletal muscle weight 71, gastroc (mouse)113127543232745567Mouse
25394551Skmw70_mskeletal muscle weight 70, EDL (mouse)113132273732594975Mouse
25394558Skmw72_mskeletal muscle weight 72, soleus (mouse)113132943032785551Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000020535   ⟹   ENSMUSP00000020535
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1132,250,069 - 32,250,873 (+)Ensembl
GRCm38.p6 Ensembl1132,300,069 - 32,300,873 (+)Ensembl
RefSeq Acc Id: NM_175000   ⟹   NP_778165
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391132,250,069 - 32,250,873 (+)NCBI
GRCm381132,300,069 - 32,300,873 (+)NCBI
MGSCv371132,200,069 - 32,200,873 (+)RGD
Celera1134,717,450 - 34,718,254 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_778165 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI39350 (Get FASTA)   NCBI Sequence Viewer  
  AAI39352 (Get FASTA)   NCBI Sequence Viewer  
  BAC30219 (Get FASTA)   NCBI Sequence Viewer  
  EDL23756 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020535
  ENSMUSP00000020535.2
RefSeq Acc Id: NP_778165   ⟸   NM_175000
- UniProtKB: Q8BYM1 (UniProtKB/TrEMBL),   B9EIX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020535   ⟸   ENSMUST00000020535
Protein Domains
Globin family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BYM1-F1-model_v2 AlphaFold Q8BYM1 1-145 view protein structure

Promoters
RGD ID:8674238
Promoter ID:EPDNEW_M15150
Type:initiation region
Name:Hbq1a_1
Description:Mus musculus hemoglobin, theta 1A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381132,300,114 - 32,300,174EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685722 AgrOrtholog
Ensembl Genes ENSMUSG00000020295 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020535 ENTREZGENE
  ENSMUST00000020535.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.490.10 UniProtKB/TrEMBL
InterPro Globin-like UniProtKB/TrEMBL
  Globin/Proto UniProtKB/TrEMBL
  Globin_subset UniProtKB/TrEMBL
  Haemoglobin_a UniProtKB/TrEMBL
KEGG Report mmu:216635 UniProtKB/TrEMBL
MGD MGI:2685722 ENTREZGENE
NCBI Gene 216635 ENTREZGENE
PANTHER HEMOGLOBIN FAMILY MEMBER UniProtKB/TrEMBL
  HEMOGLOBIN SUBUNIT THETA-1 UniProtKB/TrEMBL
Pfam Globin UniProtKB/TrEMBL
PhenoGen Hbq1a PhenoGen
PRINTS ALPHAHAEM UniProtKB/TrEMBL
PROSITE GLOBIN UniProtKB/TrEMBL
Superfamily-SCOP Globin_like UniProtKB/TrEMBL
UniProt B9EIX8 ENTREZGENE
  Q8BYM1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Hbq1a  hemoglobin, theta 1A  Hbq1  hemoglobin, theta 1  Symbol and/or name change 5135510 APPROVED