Iqsec1 (IQ motif and Sec7 domain 1) - Rat Genome Database
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Gene: Iqsec1 (IQ motif and Sec7 domain 1) Mus musculus
Analyze
Symbol: Iqsec1
Name: IQ motif and Sec7 domain 1
RGD ID: 1617348
MGI Page MGI
Description: Exhibits protein kinase binding activity. Involved in several processes, including positive regulation of focal adhesion disassembly; positive regulation of keratinocyte migration; and regulation of postsynaptic neurotransmitter receptor internalization. Localizes to Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density, intracellular component. Is expressed in central nervous system; forelimb muscle; sensory organ; and viscerocranium. Human ortholog(s) of this gene implicated in intellectual developmental disorder with short stature and behavioral abnormalities. Orthologous to human IQSEC1 (IQ motif and Sec7 domain ArfGEF 1); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 3,4-methylenedioxymethamphetamine; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW561907; BC026481; BRA; BRAG2; cI-4; cI-43; D6Ertd349; D6Ertd349e; IQ motif and SEC7 domain-containing protein 1; KIAA0763; mKIAA0763
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39690,636,578 - 90,965,766 (-)NCBIGRCm39mm39
GRCm38690,659,596 - 90,988,480 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl690,656,088 - 90,988,685 (-)EnsemblGRCm38mm10GRCm38
MGSCv37690,609,592 - 90,760,117 (-)NCBIGRCm37mm9NCBIm37
MGSCv36690,625,102 - 90,627,792 (-)NCBImm8
Celera692,543,472 - 92,701,358 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map640.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:11004510   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073  
PMID:16452087   PMID:17114649   PMID:18799693   PMID:19554387   PMID:20547133   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22886754   PMID:25490267   PMID:26884337   PMID:27507650  
PMID:27889896   PMID:28378742   PMID:28634551   PMID:28671696   PMID:28706196   PMID:28744553   PMID:29518331   PMID:30562941   PMID:30674481   PMID:31607425   PMID:32059926   PMID:32325033  
PMID:32341099   PMID:32581705  


Genomics

Comparative Map Data
Iqsec1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39690,636,578 - 90,965,766 (-)NCBIGRCm39mm39
GRCm38690,659,596 - 90,988,480 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl690,656,088 - 90,988,685 (-)EnsemblGRCm38mm10GRCm38
MGSCv37690,609,592 - 90,760,117 (-)NCBIGRCm37mm9NCBIm37
MGSCv36690,625,102 - 90,627,792 (-)NCBImm8
Celera692,543,472 - 92,701,358 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map640.16NCBI
IQSEC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl312,897,043 - 13,283,281 (-)EnsemblGRCh38hg38GRCh38
GRCh38312,897,043 - 13,283,257 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37312,938,542 - 13,324,757 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37312,938,542 - 13,114,652 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36312,914,374 - 12,983,960 (-)NCBINCBI36hg18NCBI36
Build 34312,914,373 - 12,983,960NCBI
Celera312,877,006 - 13,052,894 (-)NCBI
Cytogenetic Map3p25.2-p25.1NCBI
HuRef312,872,445 - 13,048,384 (-)NCBIHuRef
CHM1_1312,888,737 - 13,064,773 (-)NCBICHM1_1
Iqsec1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24123,168,719 - 123,488,300 (-)NCBI
Rnor_6.0 Ensembl4123,307,624 - 123,453,478 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04123,400,717 - 123,454,656 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04187,091,489 - 187,212,029 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4112,091,878 - 112,411,666 (-)NCBICelera
Cytogenetic Map4q34NCBI
Iqsec1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542913,246,294 - 13,376,568 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542913,246,585 - 13,373,189 (+)NCBIChiLan1.0ChiLan1.0
IQSEC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1313,165,134 - 13,235,377 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl313,167,299 - 13,235,285 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0312,820,552 - 13,202,925 (-)NCBIMhudiblu_PPA_v0panPan3
IQSEC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl203,241,052 - 3,522,859 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1203,241,058 - 3,403,394 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Iqsec1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936898318,564 - 425,785 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IQSEC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1371,030,878 - 71,366,685 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11371,203,967 - 71,366,685 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21378,945,020 - 78,992,150 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IQSEC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12248,873,240 - 49,050,666 (-)NCBI
ChlSab1.1 Ensembl2248,872,925 - 49,050,625 (-)Ensembl

Position Markers
RH127108  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38690,799,587 - 90,799,818UniSTSGRCm38
MGSCv37690,749,581 - 90,749,812UniSTSGRCm37
Celera692,690,824 - 92,691,055UniSTS
Cytogenetic Map6D1UniSTS
cM Map638.0UniSTS
Whitehead/MRC_RH6932.51UniSTS
UniSTS:235495  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38690,662,202 - 90,662,412UniSTSGRCm38
MGSCv37690,612,196 - 90,612,406UniSTSGRCm37
Celera692,546,073 - 92,546,283UniSTS
Cytogenetic Map6D1UniSTS
cM Map638.0UniSTS
UniSTS:235497  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38690,777,850 - 90,777,929UniSTSGRCm38
MGSCv37690,727,844 - 90,727,923UniSTSGRCm37
Celera692,669,319 - 92,669,398UniSTS
Cytogenetic Map6D1UniSTS
cM Map638.0UniSTS
RH127019  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38690,659,103 - 90,659,346UniSTSGRCm38
MGSCv37690,609,097 - 90,609,340UniSTSGRCm37
Cytogenetic Map6D1UniSTS
cM Map638.0UniSTS
Whitehead/MRC_RH6933.11UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690795610124795846Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2609
Count of miRNA genes:795
Interacting mature miRNAs:1025
Transcripts:ENSMUST00000101151, ENSMUST00000101153, ENSMUST00000133492, ENSMUST00000141434, ENSMUST00000146977, ENSMUST00000154198, ENSMUST00000156834
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001134384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001356440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017321532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017321533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC165974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000101151   ⟹   ENSMUSP00000098710
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,659,598 - 90,810,123 (-)Ensembl
RefSeq Acc Id: ENSMUST00000101153   ⟹   ENSMUSP00000098712
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,656,088 - 90,716,529 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133492
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,690,662 - 90,736,687 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141434
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,662,812 - 90,667,999 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146977
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,694,599 - 90,757,550 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154198
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,662,628 - 90,668,651 (-)Ensembl
RefSeq Acc Id: ENSMUST00000156834   ⟹   ENSMUSP00000118802
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,690,532 - 90,764,141 (-)Ensembl
RefSeq Acc Id: ENSMUST00000204983
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,659,598 - 90,662,288 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205068
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,689,818 - 90,694,696 (-)Ensembl
RefSeq Acc Id: ENSMUST00000212100   ⟹   ENSMUSP00000148669
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,660,981 - 90,988,685 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238821   ⟹   ENSMUSP00000159115
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,670,409 - 90,781,972 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238855
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl690,777,742 - 90,782,081 (-)Ensembl
RefSeq Acc Id: NM_001134383   ⟹   NP_001127855
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,580 - 90,693,511 (-)NCBI
GRCm38690,659,598 - 90,716,529 (-)NCBI
MGSCv37690,609,592 - 90,760,117 (-)RGD
Celera692,543,472 - 92,701,358 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001134384   ⟹   NP_001127856
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,580 - 90,787,105 (-)NCBI
GRCm38690,659,598 - 90,810,123 (-)NCBI
MGSCv37690,609,592 - 90,760,117 (-)RGD
Celera692,543,472 - 92,701,358 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001356440   ⟹   NP_001343369
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,580 - 90,787,105 (-)NCBI
GRCm38690,659,598 - 90,810,123 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505983   ⟹   XP_006506046
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,965,662 (-)NCBI
GRCm38690,659,596 - 90,988,420 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505984   ⟹   XP_006506047
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,713,128 (-)NCBI
GRCm38690,659,596 - 90,736,146 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505985   ⟹   XP_006506048
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,764,063 (-)NCBI
GRCm38690,659,596 - 90,782,573 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505986   ⟹   XP_006506049
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,787,181 (-)NCBI
GRCm38690,659,596 - 90,810,203 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505987   ⟹   XP_006506050
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,741,290 (-)NCBI
GRCm38690,659,596 - 90,764,317 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505988   ⟹   XP_006506051
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,693,519 (-)NCBI
GRCm38690,659,596 - 90,716,543 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505990   ⟹   XP_006506053
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,965,662 (-)NCBI
GRCm38690,659,596 - 90,988,419 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505991   ⟹   XP_006506054
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,965,662 (-)NCBI
GRCm38690,659,596 - 90,988,419 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006505992   ⟹   XP_006506055
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,714,279 (-)NCBI
GRCm38690,659,596 - 90,737,297 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011241302   ⟹   XP_011239604
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,965,662 (-)NCBI
GRCm38690,659,596 - 90,988,417 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017321532   ⟹   XP_017177021
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,734,527 (-)NCBI
GRCm38690,659,596 - 90,757,545 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017321533   ⟹   XP_017177022
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,675,634 (-)NCBI
GRCm38690,659,596 - 90,698,659 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255340   ⟹   XP_030111200
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,965,766 (-)NCBI
GRCm38690,659,596 - 90,988,480 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255341   ⟹   XP_030111201
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,787,196 (-)NCBI
GRCm38690,659,596 - 90,810,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255342   ⟹   XP_030111202
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,764,063 (-)NCBI
GRCm38690,659,596 - 90,782,572 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255343   ⟹   XP_030111203
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,708,307 (-)NCBI
GRCm38690,659,596 - 90,731,354 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255344   ⟹   XP_030111204
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,714,279 (-)NCBI
GRCm38690,659,596 - 90,737,297 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255345   ⟹   XP_030111205
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,714,279 (-)NCBI
GRCm38690,659,596 - 90,737,297 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036166051   ⟹   XP_036021944
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,965,766 (-)NCBI
RefSeq Acc Id: XM_036166052   ⟹   XP_036021945
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,741,289 (-)NCBI
RefSeq Acc Id: XM_036166053   ⟹   XP_036021946
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39690,636,578 - 90,787,180 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001127855 (Get FASTA)   NCBI Sequence Viewer  
  NP_001127856 (Get FASTA)   NCBI Sequence Viewer  
  NP_001343369 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506046 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506047 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506048 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506049 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506050 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506051 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506053 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506054 (Get FASTA)   NCBI Sequence Viewer  
  XP_006506055 (Get FASTA)   NCBI Sequence Viewer  
  XP_011239604 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177021 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177022 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111200 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111201 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111202 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111203 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111204 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111205 (Get FASTA)   NCBI Sequence Viewer  
  XP_036021944 (Get FASTA)   NCBI Sequence Viewer  
  XP_036021945 (Get FASTA)   NCBI Sequence Viewer  
  XP_036021946 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH26481 (Get FASTA)   NCBI Sequence Viewer  
  BAC32044 (Get FASTA)   NCBI Sequence Viewer  
  BAD90418 (Get FASTA)   NCBI Sequence Viewer  
  BAE34286 (Get FASTA)   NCBI Sequence Viewer  
  Q8R0S2 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001127856   ⟸   NM_001134384
- Peptide Label: isoform b
- UniProtKB: E9PUA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001127855   ⟸   NM_001134383
- Peptide Label: isoform a
- UniProtKB: Q8R0S2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006506053   ⟸   XM_006505990
- Peptide Label: isoform X9
- UniProtKB: A0A1D5RM83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006506046   ⟸   XM_006505983
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006506049   ⟸   XM_006505986
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006506048   ⟸   XM_006505985
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006506050   ⟸   XM_006505987
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006506055   ⟸   XM_006505992
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006506047   ⟸   XM_006505984
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006506051   ⟸   XM_006505988
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006506054   ⟸   XM_006505991
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_011239604   ⟸   XM_011241302
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017177021   ⟸   XM_017321532
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017177022   ⟸   XM_017321533
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_030111200   ⟸   XM_030255340
- Peptide Label: isoform X11
RefSeq Acc Id: XP_030111201   ⟸   XM_030255341
- Peptide Label: isoform X14
RefSeq Acc Id: XP_030111202   ⟸   XM_030255342
- Peptide Label: isoform X15
RefSeq Acc Id: XP_030111205   ⟸   XM_030255345
- Peptide Label: isoform X17
RefSeq Acc Id: XP_030111204   ⟸   XM_030255344
- Peptide Label: isoform X16
RefSeq Acc Id: XP_030111203   ⟸   XM_030255343
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001343369   ⟸   NM_001356440
- Peptide Label: isoform c
RefSeq Acc Id: ENSMUSP00000159115   ⟸   ENSMUST00000238821
RefSeq Acc Id: ENSMUSP00000098712   ⟸   ENSMUST00000101153
RefSeq Acc Id: ENSMUSP00000098710   ⟸   ENSMUST00000101151
RefSeq Acc Id: ENSMUSP00000148669   ⟸   ENSMUST00000212100
RefSeq Acc Id: ENSMUSP00000118802   ⟸   ENSMUST00000156834
RefSeq Acc Id: XP_036021944   ⟸   XM_036166051
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036021946   ⟸   XM_036166053
- Peptide Label: isoform X13
RefSeq Acc Id: XP_036021945   ⟸   XM_036166052
- Peptide Label: isoform X12
Protein Domains
IQ   PH   SEC7

Promoters
RGD ID:6839500
Promoter ID:MM_KWN:46892
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   Kidney,   Lung
Transcripts:OTTMUST00000073763,   OTTMUST00000073764
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36690,617,906 - 90,618,922 (-)MPROMDB
RGD ID:6839654
Promoter ID:MM_KWN:46893
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000101151,   UC009CXQ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36690,640,221 - 90,641,527 (-)MPROMDB
RGD ID:6839497
Promoter ID:MM_KWN:46894
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001134383
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36690,666,131 - 90,667,227 (-)MPROMDB
RGD ID:6890426
Promoter ID:EPDNEW_M8664
Type:multiple initiation site
Name:Iqsec1_1
Description:Mus musculus IQ motif and Sec7 domain 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8665  EPDNEW_M8666  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38690,716,520 - 90,716,580EPDNEW
RGD ID:6890428
Promoter ID:EPDNEW_M8665
Type:single initiation site
Name:Iqsec1_2
Description:Mus musculus IQ motif and Sec7 domain 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8664  EPDNEW_M8666  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38690,763,944 - 90,764,004EPDNEW
RGD ID:6890430
Promoter ID:EPDNEW_M8666
Type:initiation region
Name:Iqsec1_3
Description:Mus musculus IQ motif and Sec7 domain 1 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8664  EPDNEW_M8665  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38690,810,062 - 90,810,122EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1196356 AgrOrtholog
Ensembl Genes ENSMUSG00000034312 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000098710 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000098712 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000118802 UniProtKB/TrEMBL
  ENSMUSP00000148669 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000159115 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000101151 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000101153 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000156834 UniProtKB/TrEMBL
  ENSMUST00000212100 UniProtKB/TrEMBL
  ENSMUST00000238821 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1000.11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IQSEC1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IQSEC_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:232227 UniProtKB/Swiss-Prot
MGD MGI:1196356 ENTREZGENE
NCBI Gene 232227 ENTREZGENE
PANTHER PTHR10663:SF327 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IQ_SEC7_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Iqsec1 PhenoGen
PROSITE PS50096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEC7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Sec7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48425 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J1U6_MOUSE UniProtKB/TrEMBL
  A0A1D5RM83 ENTREZGENE, UniProtKB/TrEMBL
  A0A5F8MPT9_MOUSE UniProtKB/TrEMBL
  E9PUA3 ENTREZGENE, UniProtKB/TrEMBL
  IQEC1_MOUSE UniProtKB/Swiss-Prot
  Q8C8Q0_MOUSE UniProtKB/TrEMBL
  Q8R0S2 ENTREZGENE
UniProt Secondary Q3TZC3 UniProtKB/Swiss-Prot
  Q5DU15 UniProtKB/Swiss-Prot