Tgm4 (transglutaminase 4 (prostate))

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Gene: Tgm4 (transglutaminase 4 (prostate)) Mus musculus

Analyze

Symbol:

Tgm4

Name:

transglutaminase 4 (prostate)

RGD ID:

1617218

MGI Page

MGI

Description:

Predicted to have protein-glutamine gamma-glutamyltransferase activity. Involved in mating plug formation. Predicted to localize to Golgi apparatus and collagen-containing extracellular matrix. Is expressed in anterior prostate gland and prostate gland dorsolateral lobe. Orthologous to human TGM4 (transglutaminase 4); INTERACTS WITH 1,2-dimethylhydrazine; folic acid; titanium dioxide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

9530008N10Rik; Ea; Eapa1; experimental autoimmune prostatitis antigen 1; protein-glutamine gamma-glutamyltransferase 4; TGase-4; TGP; transglutaminase-4

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TGM4 (transglutaminase 4)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Tgm4 (transglutaminase 4)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Tgm4 (transglutaminase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TGM4 (transglutaminase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	TGM4 (transglutaminase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tgm4 (transglutaminase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TGM1 (transglutaminase 1)	HGNC	Treefam
Homo sapiens (human):	F13A1 (coagulation factor XIII A chain)	HGNC	Treefam
Homo sapiens (human):	TGM2 (transglutaminase 2)	HGNC	Treefam
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Tgm4 (transglutaminase 4)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	TGM4 (transglutaminase 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Drosophila melanogaster (fruit fly):	Tg	Alliance	DIOPT (PANTHER\|PhylomeDB\|Roundup\|TreeFam)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	122,863,806 - 122,896,623 (+)	NCBI	GRCm39		mm39
GRCm38	9	123,034,741 - 123,067,558 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	123,034,726 - 123,067,561 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	122,943,859 - 122,976,676 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	122,883,439 - 122,916,256 (+)	NCBI			mm8
Celera	9	123,496,347 - 123,518,874 (+)	NCBI		Celera
Cytogenetic Map	9	F4	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

1-naphthyl isothiocyanate (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

8'-apo-beta,psi-caroten-8'-al (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-carotene (ISO)

bisphenol A (ISO)

calcitriol (ISO)

folic acid (EXP)

indole-3-methanol (ISO)

methapyrilene (ISO)

N-nitrosodiethylamine (ISO)

phenethyl caffeate (ISO)

sodium arsenite (ISO)

testosterone (ISO)

titanium dioxide (EXP)

trichloroethene (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mating plug formation (IMP)

peptide cross-linking (IBA)

Cellular Component

collagen-containing extracellular matrix (IBA,ISO)

cytoplasm (ISO)

extracellular region (IEA)

Golgi apparatus (ISO)

Molecular Function

metal ion binding (IEA)

protein-glutamine gamma-glutamyltransferase activity (IBA)

transferase activity (IEA)

transferase activity, transferring acyl groups (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal male reproductive system physiology (IAGP)

failure of copulatory plug formation (IAGP)

impaired fertilization (IAGP)

References

References - curated


1.	RGD automated import pipeline
2.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11544199	PMID:12466851	PMID:12477932	PMID:14681479	PMID:16141072	PMID:16141073	PMID:16223778	PMID:18371946
PMID:19452452	PMID:21267068	PMID:21677750	PMID:21873635	PMID:22307675	PMID:23341775	PMID:26084804	PMID:27488082

Genomics

Comparative Map Data

Tgm4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	122,863,806 - 122,896,623 (+)	NCBI	GRCm39		mm39
GRCm38	9	123,034,741 - 123,067,558 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	123,034,726 - 123,067,561 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	122,943,859 - 122,976,676 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	122,883,439 - 122,916,256 (+)	NCBI			mm8
Celera	9	123,496,347 - 123,518,874 (+)	NCBI		Celera
Cytogenetic Map	9	F4	NCBI

TGM4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	3	44,874,608 - 44,914,990 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	3	44,874,608 - 44,914,990 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	3	44,916,098 - 44,956,093 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	44,891,102 - 44,931,092 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	3	44,891,130 - 44,931,097	NCBI
Celera	3	44,854,064 - 44,894,051 (+)	NCBI
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	44,959,958 - 44,999,946 (+)	NCBI		HuRef
CHM1_1	3	44,866,110 - 44,906,068 (+)	NCBI		CHM1_1

Tgm4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	8	132,117,279 - 132,157,485 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	132,120,452 - 132,157,485 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	131,272,260 - 131,311,091 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	127,782,460 - 127,819,491 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	8	127,802,187 - 127,838,603 (+)	NCBI
Celera	8	121,803,208 - 121,839,825 (+)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

Tgm4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	26,737,533 - 26,766,386 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	26,736,880 - 26,766,386 (-)	NCBI	ChiLan1.0	ChiLan1.0

TGM4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	45,830,764 - 45,870,208 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	45,830,764 - 45,870,208 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	44,775,855 - 44,815,691 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

TGM4
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	6,362,600 - 6,391,099 (+)	NCBI
ChlSab1.1 Ensembl	22	6,362,782 - 6,390,223 (+)	Ensembl

Tgm4
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	75,597,903 - 75,619,589 (-)	NCBI

Position Markers

AW742220

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	123,064,694 - 123,064,941	UniSTS	GRCm38
MGSCv37	9	122,973,812 - 122,974,059	UniSTS	GRCm37
Celera	9	123,516,010 - 123,516,257	UniSTS
Cytogenetic Map	9	F4	UniSTS
Whitehead/MRC_RH	9	1210.79	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10412242	Alpq8_m	alcohol preference QTL 8 (mouse)			Not determined		9	89284925	123284925	Mouse
1301649	Psl1_m	promotion susceptibility QTL 1 (mouse)			Not determined		9	89412277	123412396	Mouse
18182932	Metl3_m	metabolite locus 3, N-acetylglutamate (mouse)					9	89563342	123563342	Mouse
12910770	Splic1_m	spleen iron content 1 (mouse)					9	91413879	124595110	Mouse
12910772	Lvic6_m	liver iron content 6 (mouse)					9	91413879	124595110	Mouse
12910773	Splic3_m	spleen iron content 3 (mouse)					9	91413879	124595110	Mouse
1558767	Skmw11_m	skeletal muscle weight 11 (mouse)			Not determined		9	91641084	124595110	Mouse
13463474	Hbbcq5_m	hemoglobin concentration QTL 5 (mouse)					9	91641084	124595110	Mouse
13463475	Hctq7_m	hematocrit QTL 7 (mouse)					9	91641084	124595110	Mouse
13463477	Rbc9_m	red blood cell count 9 (mouse)					9	91641084	124595110	Mouse
13463478	Mchq18_m	mean corpuscular hemoglobin QTL 18 (mouse)					9	91641084	124595110	Mouse
13463480	Mchcq2_m	mean corpuscular hemoglobin concentration QTL 2 (mouse)					9	91641084	124595110	Mouse
12904937	Edlmmq9_m	extensor digitorum longus muscle mass QTL 9 (mouse)					9	91683173	124595110	Mouse
12904947	Tammq7_m	tibialis anterior muscle mass QTL 7 (mouse)					9	91683173	124595110	Mouse
12904961	Gmmq7_m	gastrocnemius muscle mass QTL 7 (mouse)					9	91683173	124595110	Mouse
1302001	Bdln5_m	body length 5 (mouse)			Not determined		9	93762590	124595110	Mouse
1301484	Bwq6_m	body weight (mouse)			Not determined		9	93762590	124595110	Mouse
14746992	Manh67_m	mandible shape 67 (mouse)					9	94036768	124595110	Mouse
11537364	Cnes5_m	C. neoformans susceptibility locus 5 (mouse)					9	96917590	124595110	Mouse
1301297	Lcho1_m	liver cholesterol 1 (mouse)			Not determined		9	101060861	124595110	Mouse
1357627	Tgq2_m	triglyceride QTL 2 (mouse)			Not determined		9	102000187	124595110	Mouse
1357648	Obq18_m	obesity QTL 18 (mouse)			Not determined		9	102000187	124595110	Mouse
1301789	Pbwg4_m	postnatal body weight growth 4 (mouse)			Not determined		9	103289445	124595110	Mouse
10412290	Pvacm1l_m	plasma vascular cell adhesion molecule 1 levels (mouse)			Not determined		9	103289445	124595110	Mouse
12879896	Berr3_m	berghei resistance locus 3 (mouse)					9	103289445	124595110	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	600
Count of miRNA genes:	431
Interacting mature miRNAs:	503
Transcripts:	ENSMUST00000026893, ENSMUST00000128572, ENSMUST00000143364, ENSMUST00000171897
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_177911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017313442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC133650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF486627	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK035279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC141297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC145622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000026893 ⟹ ENSMUSP00000026893

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	123,034,726 - 123,067,561 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000128572

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	123,040,432 - 123,049,035 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000143364

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	123,034,739 - 123,035,831 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000171897

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	123,034,740 - 123,052,699 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000214552

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	123,061,855 - 123,065,443 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000215247 ⟹ ENSMUSP00000149120

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	123,034,743 - 123,067,016 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000217607 ⟹ ENSMUSP00000149061

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	9	123,034,726 - 123,061,656 (+)	Ensembl

RefSeq Acc Id:

NM_177911 ⟹ NP_808579

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	122,863,806 - 122,896,623 (+)	NCBI
GRCm38	9	123,034,741 - 123,067,558 (+)	ENTREZGENE
MGSCv37	9	122,943,859 - 122,976,676 (+)	RGD
Celera	9	123,496,352 - 123,518,874 (+)	ENTREZGENE
cM Map	9		ENTREZGENE

Sequence:

show sequence

ATGATTCTGGCAGTGCCTTTGGCATCAGACTAGAGTCTTGACAGGGCTGCAGAGAGAGGTAGCA
GGACCATGGACTCCAGGAATGTGCTTATCATTTACGCTGTGAATGTGGAGAGAAAGCTGAATGC
TGCTGCCCACCACACATCCGAGTACCAGACCAAGAAGCTCGTGCTGAGGCGTGGACAGATATTC
ACTCTGAAGGTGATACTGAACCGACCTCTCCAACCTCAGGATGAGCTGAAGGTGACATTCACTT
CCGGACAGAGAGACCCACCCTACATGGTGGAGCTTGATCCAGTGACATCCTACCGTTCTAAGGG
CTGGCAGGTGAAGATTGCCAAACAGTCTGGCGTAGAGGTTATTCTGAATGTCATCAGTGCTGCT
GACGCCGTAGTGGGAAGGTACAAGATGAGGGTGAACGAGTATAAAGCTGGAGTATTCTACCTTC
TCTTCAATCCGTGGTGCTCAGACGACAGTGTCTTCATGGCTAGTGAGGAAGAACGAGCAGAGTA
CATCCTTAATGACACCGGCTACATGTACATGGGTTTCGCCAAACAAATTAAAGAGAAGCCCTGG
ACCTTTGGTCAGTTTGAGAAGCACATCCTGAGCTGCTGCTTCAACTTGTTGTTCCAGTTGGAGA
ACAATGAGATGCAGAACCCAGTGCTTGTGTCCAGGGCCATCTGTACTATGATGTGTGCTGCGAA
CGGCGGAGTGCTGATGGGGAACTGGACAGGAGACTATGCCGATGGCACGGCCCCATATGTGTGG
ACCAGCAGTGTACCCATCCTGCAGCAGCATTATGTCACCAGGATGCCTGTACGCTACGGCCAGT
GCTGGGTTTTCTCTGGAATCCTGACCACAGCACTGAGAGCAGTGGGTATCCCAGCTCGAAGCGT
GACTAACTTTGAGTCAGCCCATGATACAGAAAAGAACCTCACAGTAGACATCTACCTGGATGAA
TCGGGCAAGACAATTCCACATCTGACCAAAGACTCTGTCTGGAATTTCCACGTGTGGACAGATG
CCTGGATGAAAAGGCAGGATCTACCTCATGGCTATGATGGCTGGCAGGTCCTGGATTCTACACC
CCAGGAAATCAGCGATGGAGGCTTCCGCACCGGGCCTTCACCACTGACTGCTATTCGCCAGGGA
TTGATCCAGATGAAGTATGACACCACGTTTGTGTTCACGGAGGTCAATGGTGACAAGTTTATCT
GGTTGGTGAAGCAGAACCAGGAAAGGGAGAAGAATATTCTCATCGCCGTGGAGACTGCCAGCAT
CGGCAAGAAAATCAGCACCAAGATGGTGGGCGAGAACAGGCGTGAAGATATAACCTTGCAGTAC
AAGTTCCCAGAAGGCAGCCCAGAGGAGAGGAAGGTCATGGCGAAGGCTTCTGGTAAACCTTCTG
ATGACAAGCTCAACTCTCGGACTCTGAACAACTCTCTTCAGATATCTGTCCTCCAGAACTCGTT
GGAGTTAGGAGCTCCCATCTATTTGACCATAACTTTGAAAAGAAAAACCGCCACCCCACAGAAT
GTCAACATTTCCTGCTCCCTCAACCTGCAGACATACACAGGCAACAAGAAGACAAACCTGGGAG
TCATCCAGAAGACTGTGCAGATCCACGGCCAAGAATCAAGGGTGTTTCTCACCATGGATGCCAG
CTACTACATCTATAAACTGGGCATGGTTGATGATGAGATGGTCATTGGAGGGTTCATCATTGCA
GAAATTGTAGATTCTGGTGAAAGGGTGGCCACTGATACAACCCTGTGTTTCCTGTACTCTGCCT
TCTCTGTAGAGATGCCGAGCACAGGCAAGGTCAAGCAGCCTCTCGTCATCACCAGCAAATTCAC
GAACACCCTGCCCATCCCTTTGACTAACATCAAGTTCTCAGTGGAAAGCCTGGGCCTCGCTAAC
ATGAAATCCTGGGAACAAGAGACAGTGCCACCTGGAAAGACCATCACTTTCCAAATGGAATGCA
CCCCAGTGAAAGCTGGACCCCAGAAATTCATTGTCAAGTTTATTTCCAGACAAGTGAAAGAGGT
TCATGCCGAGAAGGTCGTTCTCATCAGCAAGTAGCACATTTGATACCATGGAGATGGAGGCAGG
AGCCCTGATTGGCTCTGAGCCTTGGCTAAGCATGTTAACATTTTCTAAATTGCATTTAGCTTTC
AGGTCAGGGATGGTTAAATTTGATTATGCGTGTGAAGGCACATTCAAGAGCCAGCCCAGCAAGA
CAGAGCTCAAAGGCCGATGTCACCACAGGCAGTAGCTCCAGGGAGCCAGAGAACCTGGGCACAT
GTCACAGGCAAACATTTCAAATACATATTTAGGAATTGTGGCCTCAGAAGACAGTGCCACCGTC
ATCTGGATTCAGAACCATGTACAGAGCCCAGATATAGAAGGGCTGGAGGCATCTTCCATCTAGA
CCATGGATTCTATCAAGTCCAGGGGTGCCTGGAGGCTGTGCTGGAAGTCTTATAGAAAGCATCT
TGGAGCTGGTCCTGGGTCAGGCACTACACCCTCTTATCCCAAGGCTCTGTCCTCTTAGAAGCAG
GCCCCACGCTGGCGTGAGGCCCTCTTGCTCTGGATGAGCCATGGGAGGTAGACCCTTTTTTTAA
GTAAGAGTCTATGGCCAGTGACAACATCTGAAGAAGCAACGTATCCTGCCCTGTTCTCGGGAGT
CTGTGCTTTGCTCTGCTGTTAAGGTATCTGCTCACATACCACTATGCTTTGAATTAAACTCTGG
CAACTTTAAGATGGC

hide sequence

RefSeq Acc Id:

XM_017313442 ⟹ XP_017168931

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	122,863,875 - 122,896,621 (+)	NCBI
GRCm38	9	123,034,810 - 123,067,556 (+)	NCBI

Sequence:

show sequence

ATGGACTCCAGGAATGCCCCAGTCGAGGAGCGGAGAAAGCTCAGGTTGTATCTCTGGACTCTGC
GGAAACTCATCCTGAATGCTGAGAGCCCTTTGGAGCTGGGGAAACCCCTTAGTCCAACAGCTGG
ACTGACAGAGACGGAGAGCAGTCAAACGCTCCCCTCCCCACCACTCCTCGATAGCATCCAGGAA
CCAGTTTACAGACCTGGGAGGGAGTTAACCTTGTTTGTGTCTTCCCGCTGTGTGCTAACAGTGC
TTATCATTTACGCTGTGAATGTGGAGAGAAAGCTGAATGCTGCTGCCCACCACACATCCGAGTA
CCAGACCAAGAAGCTCGTGCTGAGGCGTGGACAGATATTCACTCTGAAGGTGATACTGAACCGA
CCTCTCCAACCTCAGGATGAGCTGAAGGTGACATTCACTTCCGGACAGAGAGACCCACCCTACA
TGGTGGAGCTTGATCCAGTGACATCCTACCGTTCTAAGGGCTGGCAGGTGAAGATTGCCAAACA
GTCTGGCGTAGAGGTTATTCTGAATGTCATCAGTGCTGCTGACGCCGTAGTGGGAAGGTACAAG
ATGAGGGTGAACGAGTATAAAGCTGGAGTATTCTACCTTCTCTTCAATCCGTGGTGCTCAGACG
ACAGTGTCTTCATGGCTAGTGAGGAAGAACGAGCAGAGTACATCCTTAATGACACCGGCTACAT
GTACATGGGTTTCGCCAAACAAATTAAAGAGAAGCCCTGGACCTTTGGTCAGTTTGAGAAGCAC
ATCCTGAGCTGCTGCTTCAACTTGTTGTTCCAGTTGGAGAACAATGAGATGCAGAACCCAGTGC
TTGTGTCCAGGGCCATCTGTACTATGATGTGTGCTGCGAACGGCGGAGTGCTGATGGGGAACTG
GACAGGAGACTATGCCGATGGCACGGCCCCATATGTGTGGACCAGCAGTGTACCCATCCTGCAG
CAGCATTATGTCACCAGGATGCCTGTACGCTACGGCCAGTGCTGGGTTTTCTCTGGAATCCTGA
CCACAGCACTGAGAGCAGTGGGTATCCCAGCTCGAAGCGTGACTAACTTTGAGTCAGCCCATGA
TACAGAAAAGAACCTCACAGTAGACATCTACCTGGATGAATCGGGCAAGACAATTCCACATCTG
ACCAAAGACTCTGTCTGGAATTTCCACGTGTGGACAGATGCCTGGATGAAAAGGCAGGATCTAC
CTCATGGCTATGATGGCTGGCAGGTCCTGGATTCTACACCCCAGGAAATCAGCGATGGAGGCTT
CCGCACCGGGCCTTCACCACTGACTGCTATTCGCCAGGGATTGATCCAGATGAAGTATGACACC
ACGTTTGTGTTCACGGAGGTCAATGGTGACAAGTTTATCTGGTTGGTGAAGCAGAACCAGGAAA
GGGAGAAGAATATTCTCATCGCCGTGGAGACTGCCAGCATCGGCAAGAAAATCAGCACCAAGAT
GGTGGGCGAGAACAGGCGTGAAGATATAACCTTGCAGTACAAGTTCCCAGAAGGCAGCCCAGAG
GAGAGGAAGGTCATGGCGAAGGCTTCTGGTAAACCTTCTGATGACAAGCTCAACTCTCGGACTC
TGAACAACTCTCTTCAGATATCTGTCCTCCAGAACTCGTTGGAGTTAGGAGCTCCCATCTATTT
GACCATAACTTTGAAAAGAAAAACCGCCACCCCACAGAATGTCAACATTTCCTGCTCCCTCAAC
CTGCAGACATACACAGGCAACAAGAAGACAAACCTGGGAGTCATCCAGAAGACTGTGCAGATCC
ACGGCCAAGAATCAAGGGTGTTTCTCACCATGGATGCCAGCTACTACATCTATAAACTGGGCAT
GGTTGATGATGAGATGGTCATTGGAGGGTTCATCATTGCAGAAATTGTAGATTCTGGTGAAAGG
GTGGCCACTGATACAACCCTGTGTTTCCTGTACTCTGCCTTCTCTGTAGAGATGCCGAGCACAG
GCAAGGTCAAGCAGCCTCTCGTCATCACCAGCAAATTCACGAACACCCTGCCCATCCCTTTGAC
TAACATCAAGTTCTCAGTGGAAAGCCTGGGCCTCGCTAACATGAAATCCTGGGAACAAGAGACA
GTGCCACCTGGAAAGACCATCACTTTCCAAATGGAATGCACCCCAGTGAAAGCTGGACCCCAGA
AATTCATTGTCAAGTTTATTTCCAGACAAGTGAAAGAGGTTCATGCCGAGAAGGTCGTTCTCAT
CAGCAAGTAGCACATTTGATACCATGGAGATGGAGGCAGGAGCCCTGATTGGCTCTGAGCCTTG
GCTAAGCATGTTAACATTTTCTAAATTGCATTTAGCTTTCAGGTCAGGGATGGTTAAATTTGAT
TATGCGTGTGAAGGCACATTCAAGAGCCAGCCCAGCAAGACAGAGCTCAAAGGCCGATGTCACC
ACAGGCAGTAGCTCCAGGGAGCCAGAGAACCTGGGCACATGTCACAGGCAAACATTTCAAATAC
ATATTTAGGAATTGTGGCCTCAGAAGACAGTGCCACCGTCATCTGGATTCAGAACCATGTACAG
AGCCCAGATATAGAAGGGCTGGAGGCATCTTCCATCTAGACCATGGATTCTATCAAGTCCAGGG
GTGCCTGGAGGCTGTGCTGGAAGTCTTATAGAAAGCATCTTGGAGCTGGTCCTGGGTCAGGCAC
TACACCCTCTTATCCCAAGGCTCTGTCCTCTTAGAAGCAGGCCCCACGCTGGCGTGAGGCCCTC
TTGCTCTGGATGAGCCATGGGAGGTAGACCCTTTTTTTAAGTAAGAGTCTATGGCCAGTGACAA
CATCTGAAGAAGCAACGTATCCTGCCCTGTTCTCGGGAGTCTGTGCTTTGCTCTGCTGTTAAGG
TATCTGCTCACATACCACTATGCTTTGAATTAAACTCTGGCAACTTTAAGATG

hide sequence

Protein Sequences


Protein RefSeqs	NP_808579	(Get FASTA)	NCBI Sequence Viewer
	XP_017168931	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI41298	(Get FASTA)	NCBI Sequence Viewer
	AAI45623	(Get FASTA)	NCBI Sequence Viewer
	AAM45940	(Get FASTA)	NCBI Sequence Viewer
	BAC29013	(Get FASTA)	NCBI Sequence Viewer
	Q8BZH1	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_808579 ⟸ NM_177911

- UniProtKB:

Q8BZH1 (UniProtKB/Swiss-Prot), A0A0R4J071 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDSRNVLIIYAVNVERKLNAAAHHTSEYQTKKLVLRRGQIFTLKVILNRPLQPQDELKVTFTSG
QRDPPYMVELDPVTSYRSKGWQVKIAKQSGVEVILNVISAADAVVGRYKMRVNEYKAGVFYLLF
NPWCSDDSVFMASEEERAEYILNDTGYMYMGFAKQIKEKPWTFGQFEKHILSCCFNLLFQLENN
EMQNPVLVSRAICTMMCAANGGVLMGNWTGDYADGTAPYVWTSSVPILQQHYVTRMPVRYGQCW
VFSGILTTALRAVGIPARSVTNFESAHDTEKNLTVDIYLDESGKTIPHLTKDSVWNFHVWTDAW
MKRQDLPHGYDGWQVLDSTPQEISDGGFRTGPSPLTAIRQGLIQMKYDTTFVFTEVNGDKFIWL
VKQNQEREKNILIAVETASIGKKISTKMVGENRREDITLQYKFPEGSPEERKVMAKASGKPSDD
KLNSRTLNNSLQISVLQNSLELGAPIYLTITLKRKTATPQNVNISCSLNLQTYTGNKKTNLGVI
QKTVQIHGQESRVFLTMDASYYIYKLGMVDDEMVIGGFIIAEIVDSGERVATDTTLCFLYSAFS
VEMPSTGKVKQPLVITSKFTNTLPIPLTNIKFSVESLGLANMKSWEQETVPPGKTITFQMECTP
VKAGPQKFIVKFISRQVKEVHAEKVVLISK

hide sequence

RefSeq Acc Id:

XP_017168931 ⟸ XM_017313442

- Peptide Label:

isoform X1

- Sequence:

show sequence

MDSRNAPVEERRKLRLYLWTLRKLILNAESPLELGKPLSPTAGLTETESSQTLPSPPLLDSIQE
PVYRPGRELTLFVSSRCVLTVLIIYAVNVERKLNAAAHHTSEYQTKKLVLRRGQIFTLKVILNR
PLQPQDELKVTFTSGQRDPPYMVELDPVTSYRSKGWQVKIAKQSGVEVILNVISAADAVVGRYK
MRVNEYKAGVFYLLFNPWCSDDSVFMASEEERAEYILNDTGYMYMGFAKQIKEKPWTFGQFEKH
ILSCCFNLLFQLENNEMQNPVLVSRAICTMMCAANGGVLMGNWTGDYADGTAPYVWTSSVPILQ
QHYVTRMPVRYGQCWVFSGILTTALRAVGIPARSVTNFESAHDTEKNLTVDIYLDESGKTIPHL
TKDSVWNFHVWTDAWMKRQDLPHGYDGWQVLDSTPQEISDGGFRTGPSPLTAIRQGLIQMKYDT
TFVFTEVNGDKFIWLVKQNQEREKNILIAVETASIGKKISTKMVGENRREDITLQYKFPEGSPE
ERKVMAKASGKPSDDKLNSRTLNNSLQISVLQNSLELGAPIYLTITLKRKTATPQNVNISCSLN
LQTYTGNKKTNLGVIQKTVQIHGQESRVFLTMDASYYIYKLGMVDDEMVIGGFIIAEIVDSGER
VATDTTLCFLYSAFSVEMPSTGKVKQPLVITSKFTNTLPIPLTNIKFSVESLGLANMKSWEQET
VPPGKTITFQMECTPVKAGPQKFIVKFISRQVKEVHAEKVVLISK

hide sequence

RefSeq Acc Id:

ENSMUSP00000026893 ⟸ ENSMUST00000026893

RefSeq Acc Id:

ENSMUSP00000149061 ⟸ ENSMUST00000217607

RefSeq Acc Id:

ENSMUSP00000149120 ⟸ ENSMUST00000215247

Protein Domains

TGc Transglut_C Transglut_N

Promoters

RGD ID:

8671324

Promoter ID:

EPDNEW_M13692

Type:

multiple initiation site

Name:

Tgm4_1

Description:

Mus musculus transglutaminase 4 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	9	123,034,743 - 123,034,803	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3027002	AgrOrtholog
Ensembl Genes	ENSMUSG00000025787	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000026893	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUSP00000149061	UniProtKB/TrEMBL
	ENSMUSP00000149120	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000026893	ENTREZGENE, UniProtKB/TrEMBL
	ENSMUST00000215247	UniProtKB/TrEMBL
	ENSMUST00000217607	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.90.260.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_E-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Papain-like_cys_pep_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglutaminase-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglutaminase-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglutaminase_animal	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglutaminase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglutaminase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglutaminase_C_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglutaminase_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:331046	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:3027002	ENTREZGENE
NCBI Gene	331046	ENTREZGENE
Pfam	Transglut_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglut_core	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transglut_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Tgm4	PhenoGen
PIRSF	TGM_EBP42	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	TRANSGLUTAMINASES	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	TGc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF49309	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF54001	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF81296	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Mm.195309	ENTREZGENE
UniProt	A0A0R4J071	ENTREZGENE, UniProtKB/TrEMBL
	A0A1L1SQH9_MOUSE	UniProtKB/TrEMBL
	A0A1L1SQM7_MOUSE	UniProtKB/TrEMBL
	Q8BZH1	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	B7ZP44	UniProtKB/Swiss-Prot
	Q8K460	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)