Erich6 (glutamate rich 6) - Rat Genome Database

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Gene: Erich6 (glutamate rich 6) Mus musculus
Analyze
Symbol: Erich6
Name: glutamate rich 6
RGD ID: 1617134
MGI Page MGI
Description: Orthologous to human ERICH6 (glutamate rich 6).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 4932431H17Rik; Fam19; Fam194a; family with sequence similarity 194, member A; glutamate-rich protein 6; hypothetical protein LOC545527
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39358,523,721 - 58,544,639 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl358,523,721 - 58,544,628 (-)EnsemblGRCm39 Ensembl
GRCm38358,616,300 - 58,637,220 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl358,616,300 - 58,637,207 (-)EnsemblGRCm38mm10GRCm38
MGSCv37358,420,222 - 58,441,129 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36358,704,229 - 58,725,136 (-)NCBIMGSCv36mm8
Celera358,318,976 - 58,331,813 (-)NCBICelera
Cytogenetic Map3DNCBI
cM Map328.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21677750   PMID:29518331  


Genomics

Comparative Map Data
Erich6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39358,523,721 - 58,544,639 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl358,523,721 - 58,544,628 (-)EnsemblGRCm39 Ensembl
GRCm38358,616,300 - 58,637,220 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl358,616,300 - 58,637,207 (-)EnsemblGRCm38mm10GRCm38
MGSCv37358,420,222 - 58,441,129 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36358,704,229 - 58,725,136 (-)NCBIMGSCv36mm8
Celera358,318,976 - 58,331,813 (-)NCBICelera
Cytogenetic Map3DNCBI
cM Map328.64NCBI
ERICH6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383150,659,885 - 150,703,920 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3150,659,885 - 150,703,971 (-)EnsemblGRCh38hg38GRCh38
GRCh373150,377,672 - 150,421,707 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363151,860,365 - 151,904,432 (-)NCBINCBI36Build 36hg18NCBI36
Celera3148,790,766 - 148,834,837 (-)NCBICelera
Cytogenetic Map3q25.1NCBI
HuRef3147,751,355 - 147,795,444 (-)NCBIHuRef
CHM1_13150,340,702 - 150,384,788 (-)NCBICHM1_1
T2T-CHM13v2.03153,411,110 - 153,455,167 (-)NCBIT2T-CHM13v2.0
Erich6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82145,001,833 - 145,027,935 (-)NCBIGRCr8
mRatBN7.22142,851,905 - 142,878,010 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2142,851,905 - 142,884,320 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2149,490,290 - 149,516,306 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02147,596,953 - 147,622,861 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02142,229,385 - 142,255,293 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02148,812,060 - 148,861,470 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2148,811,907 - 148,838,441 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02168,229,962 - 168,256,064 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42147,960,550 - 147,986,652 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2137,280,288 - 137,306,254 (-)NCBICelera
Cytogenetic Map2q26NCBI
Erich6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554481,824,395 - 1,859,042 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554481,827,296 - 1,860,699 (-)NCBIChiLan1.0ChiLan1.0
ERICH6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22148,549,083 - 148,594,337 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13148,553,812 - 148,599,066 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03147,678,236 - 147,723,217 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13155,251,798 - 155,295,829 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3155,251,798 - 155,295,829 (-)Ensemblpanpan1.1panPan2
ERICH6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12345,290,021 - 45,321,238 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2345,290,028 - 45,320,774 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2345,157,357 - 45,188,380 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02345,917,984 - 45,949,508 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2345,917,991 - 45,950,109 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12345,508,446 - 45,539,934 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02345,560,355 - 45,591,928 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02345,836,509 - 45,867,999 (-)NCBIUU_Cfam_GSD_1.0
Erich6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560290,692,184 - 90,715,445 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367581,052,357 - 1,075,657 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367581,052,410 - 1,077,918 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERICH6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1390,870,496 - 90,911,109 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11390,868,620 - 90,915,297 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21398,951,848 - 99,001,069 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ERICH6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11539,983,346 - 40,029,632 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1539,984,115 - 40,029,625 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604112,802,820 - 12,849,694 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Erich6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473028,066,422 - 28,101,652 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473028,066,416 - 28,115,523 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:111
Count of miRNA genes:106
Interacting mature miRNAs:110
Transcripts:ENSMUST00000041115
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
14746977Manh53_mmandible shape 53 (mouse)33592528069925280Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
15039332Nmrs6_mNAFLD-associated magnetic resonance shift 6 (mouse)33417074168170741Mouse
1301585Cd4ts1_mCD4 T cell subset 1 (mouse)Not determined33970410273704231Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11041901Lmr11b_mleishmaniasis resistance 11b (mouse)33970410273704231Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35262550986625745Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35292318386923183Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34949500583495118Mouse
15039336Nmrs2_mNAFLD-associated magnetic resonance shift 2 (mouse)33457610368576103Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35262550986625745Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34949500583495118Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
10755516Amzn1_manatomical modifier of Zfp423 1 (mouse)33970410273704231Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
9587784Afw13_mabdominal fat weight QTL 13 (mouse)Not determined33375204567752228Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35262550986625745Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4935758183357581Mouse
18337272Bmd46_mbone mineral density 46, males (mouse)33540742169407421Mouse
11039513Ltpr3a_mLeishmania tropica response 3a (mouse)33970410273704231Mouse
1300961Bh4p_mbar holding four paws (mouse)Not determined33183785465837997Mouse
10043882Bwtq13_mbody weight QTL 13 (mouse)Not determined33375204567752228Mouse
10412073Ssen2_msuseptibility to Sendai virus 2 (mouse)Not determined33353546567535615Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
1300587Aod2_mautoimmune ovarian dysgenesis 2 (mouse)Not determined33717974268716946Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884389Skwq10_mskull length QTL 10, 16 week (mouse)34395443565307421Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000041115   ⟹   ENSMUSP00000040882
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl358,523,721 - 58,544,628 (-)Ensembl
GRCm38.p6 Ensembl358,616,300 - 58,637,207 (-)Ensembl
RefSeq Acc Id: NM_001081262   ⟹   NP_001074731
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39358,523,721 - 58,544,628 (-)NCBI
GRCm38358,616,300 - 58,637,207 (-)NCBI
MGSCv37358,420,222 - 58,441,129 (-)RGD
Celera358,318,976 - 58,331,813 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501709   ⟹   XP_006501772
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39358,532,427 - 58,544,639 (-)NCBI
GRCm38358,625,006 - 58,637,220 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011240167   ⟹   XP_011238469
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39358,523,721 - 58,544,639 (-)NCBI
GRCm38358,616,300 - 58,637,220 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017319654   ⟹   XP_017175143
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39358,531,734 - 58,544,639 (-)NCBI
GRCm38358,624,313 - 58,637,220 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001074731 (Get FASTA)   NCBI Sequence Viewer  
  XP_006501772 (Get FASTA)   NCBI Sequence Viewer  
  XP_011238469 (Get FASTA)   NCBI Sequence Viewer  
  XP_017175143 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D3Z6S9 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000040882
  ENSMUSP00000040882.7
RefSeq Acc Id: NP_001074731   ⟸   NM_001081262
- UniProtKB: D3Z6S9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006501772   ⟸   XM_006501709
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011238469   ⟸   XM_011240167
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017175143   ⟸   XM_017319654
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000040882   ⟸   ENSMUST00000041115

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z6S9-F1-model_v2 AlphaFold D3Z6S9 1-713 view protein structure

Promoters
RGD ID:6833294
Promoter ID:MM_KWN:34404
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000041115,   NM_001081262,   UC008PHZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36358,440,411 - 58,440,911 (-)MPROMDB
RGD ID:6880718
Promoter ID:EPDNEW_M3810
Type:initiation region
Name:Erich6_1
Description:Mus musculus glutamate rich 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38358,637,215 - 58,637,275EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3588212 AgrOrtholog
Ensembl Genes ENSMUSG00000070471 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000041115 ENTREZGENE
  ENSMUST00000041115.7 UniProtKB/Swiss-Prot
InterPro FAM194_C UniProtKB/Swiss-Prot
KEGG Report mmu:545527 UniProtKB/Swiss-Prot
MGD MGI:3588212 ENTREZGENE
NCBI Gene 545527 ENTREZGENE
PANTHER GLUTAMATE-RICH PROTEIN 6 UniProtKB/Swiss-Prot
  SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20 UniProtKB/Swiss-Prot
Pfam FAM194 UniProtKB/Swiss-Prot
PhenoGen Erich6 PhenoGen
UniProt D3Z6S9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-30 Erich6  glutamate rich 6  Fam194a  family with sequence similarity 194, member A  Symbol and/or name change 5135510 APPROVED