Nufip2 (nuclear fragile X mental retardation protein interacting protein 2) - Rat Genome Database
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Gene: Nufip2 (nuclear fragile X mental retardation protein interacting protein 2) Mus musculus
Analyze
Symbol: Nufip2
Name: nuclear fragile X mental retardation protein interacting protein 2
RGD ID: 1616769
MGI Page MGI
Description: Predicted to have RNA binding activity. Predicted to localize to several cellular components, including cytoplasmic stress granule; nuclear body; and polysomal ribosome. Orthologous to human NUFIP2 (nuclear FMR1 interacting protein 2); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110001M19Rik; 82 kDa FMRP-interacting protein; 82-FIP; 9530056D24Rik; AI256692; AI461731; FMRP-interacting protein 2; mKIAA1321; nuclear fragile X mental retardation-interacting protein 2; PIG1; proliferation-inducing gene 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,576,566 - 77,608,792 (+)NCBIGRCm39mm39
GRCm381177,685,764 - 77,717,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,686,155 - 77,741,921 (+)EnsemblGRCm38mm10GRCm38
MGSCv371177,499,641 - 77,531,468 (+)NCBIGRCm37mm9NCBIm37
MGSCv361177,502,350 - 77,534,161 (+)NCBImm8
Celera1185,184,653 - 85,216,467 (+)NCBICelera
Cytogenetic Map11B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
protein binding  (ISO)
RNA binding  (IBA,ISO)

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12520002   PMID:12693553   PMID:12837692   PMID:12904583   PMID:14610273  
PMID:15345747   PMID:16141072   PMID:16141073   PMID:16778019   PMID:17114649   PMID:18799693   PMID:21267068   PMID:21589869   PMID:21677750   PMID:21873635   PMID:25737280   PMID:26265008  
PMID:28671696   PMID:29352114   PMID:30196744   PMID:30335684   PMID:31040226   PMID:31138677  


Genomics

Comparative Map Data
Nufip2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,576,566 - 77,608,792 (+)NCBIGRCm39mm39
GRCm381177,685,764 - 77,717,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,686,155 - 77,741,921 (+)EnsemblGRCm38mm10GRCm38
MGSCv371177,499,641 - 77,531,468 (+)NCBIGRCm37mm9NCBIm37
MGSCv361177,502,350 - 77,534,161 (+)NCBImm8
Celera1185,184,653 - 85,216,467 (+)NCBICelera
Cytogenetic Map11B5NCBI
NUFIP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1729,255,839 - 29,294,148 (-)EnsemblGRCh38hg38GRCh38
GRCh381729,255,839 - 29,294,148 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371727,582,857 - 27,621,166 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371727,582,854 - 27,621,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361724,612,772 - 24,645,203 (-)NCBINCBI36hg18NCBI36
Celera1724,442,372 - 24,480,641 (-)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1723,791,510 - 23,829,875 (-)NCBIHuRef
CHM1_11727,645,565 - 27,683,850 (-)NCBICHM1_1
Nufip2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21062,574,922 - 62,607,729 (+)NCBI
Rnor_6.0 Ensembl1065,176,648 - 65,200,109 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01065,168,145 - 65,200,210 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01066,425,324 - 66,450,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,725,565 - 63,751,011 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1061,556,666 - 61,581,176 (+)NCBICelera
Cytogenetic Map10q25NCBI
Nufip2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554813,922,211 - 3,950,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554813,922,211 - 3,950,832 (+)NCBIChiLan1.0ChiLan1.0
NUFIP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11727,994,745 - 28,031,451 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1727,994,745 - 28,022,755 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01727,482,374 - 27,521,466 (+)NCBIMhudiblu_PPA_v0panPan3
NUFIP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl943,365,378 - 43,411,571 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1943,380,048 - 43,411,597 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Nufip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365385,411,896 - 5,435,799 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUFIP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,473,685 - 45,506,581 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11245,473,687 - 45,506,587 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21247,450,157 - 47,458,408 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUFIP2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11623,012,707 - 23,049,736 (-)NCBI
ChlSab1.1 Ensembl1623,021,413 - 23,049,756 (-)Ensembl
Nufip2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247861,778,295 - 1,808,077 (-)NCBI

Position Markers
RH136070  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv378128,726,633 - 128,726,834UniSTSGRCm37
MGSCv371177,529,614 - 77,529,811UniSTSGRCm37
Celera1185,214,613 - 85,214,810UniSTS
Celera8130,513,743 - 130,513,944UniSTS
Celera8130,512,310 - 130,512,510UniSTS
Cytogenetic Map11B5UniSTS
AI461731  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381177,716,202 - 77,716,308UniSTSGRCm38
MGSCv371177,529,704 - 77,529,810UniSTSGRCm37
Celera1185,214,703 - 85,214,809UniSTS
Cytogenetic Map11B5UniSTS
Whitehead/MRC_RH11978.96UniSTS
RH139478  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381177,715,910 - 77,716,100UniSTSGRCm38
MGSCv371177,529,412 - 77,529,602UniSTSGRCm37
Celera1185,214,411 - 85,214,601UniSTS
Cytogenetic Map11B5UniSTS
AI176383  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381177,711,648 - 77,711,880UniSTSGRCm38
MGSCv371177,525,150 - 77,525,382UniSTSGRCm37
Celera1185,210,149 - 85,210,381UniSTS
Cytogenetic Map11B5UniSTS
D11Bhm38  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381177,707,944 - 77,708,145UniSTSGRCm38
MGSCv371177,521,446 - 77,521,647UniSTSGRCm37
Celera1185,206,459 - 85,206,660UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.72UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117384671582178599Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
4141365Ltxs3_mlethal factor toxin susceptibility 3 (mouse)Not determined117768304780855532Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:944
Count of miRNA genes:556
Interacting mature miRNAs:673
Transcripts:ENSMUST00000100802, ENSMUST00000126942, ENSMUST00000155238, ENSMUST00000181023
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000100802   ⟹   ENSMUSP00000098365
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1177,686,155 - 77,712,741 (+)Ensembl
RefSeq Acc Id: ENSMUST00000126942
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1177,687,459 - 77,691,920 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155238
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1177,687,601 - 77,691,718 (+)Ensembl
RefSeq Acc Id: ENSMUST00000181023   ⟹   ENSMUSP00000137922
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1177,686,172 - 77,741,921 (+)Ensembl
RefSeq Acc Id: NM_001024205   ⟹   NP_001019376
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,576,965 - 77,608,792 (+)NCBI
GRCm381177,686,139 - 77,717,966 (+)NCBI
MGSCv371177,499,641 - 77,531,468 (+)RGD
Celera1185,184,653 - 85,216,467 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534062   ⟹   XP_006534125
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,576,566 - 77,608,792 (+)NCBI
GRCm381177,685,764 - 77,717,966 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006534063   ⟹   XP_006534126
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,578,290 - 77,608,792 (+)NCBI
GRCm381177,686,556 - 77,717,966 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156930   ⟹   XP_036012823
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,576,586 - 77,608,792 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001019376   ⟸   NM_001024205
- UniProtKB: Q5F2E7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534125   ⟸   XM_006534062
- Peptide Label: isoform X2
- UniProtKB: Q5F2E7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534126   ⟸   XM_006534063
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSMUSP00000098365   ⟸   ENSMUST00000100802
RefSeq Acc Id: ENSMUSP00000137922   ⟸   ENSMUST00000181023
RefSeq Acc Id: XP_036012823   ⟸   XM_036156930
- Peptide Label: isoform X1

Promoters
RGD ID:6821467
Promoter ID:MM_KWN:8622
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000036677,   NM_001024205
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361177,499,321 - 77,499,821 (+)MPROMDB
RGD ID:6821468
Promoter ID:MM_KWN:8623
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000018581,   OTTMUST00000018582
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361177,500,576 - 77,501,407 (+)MPROMDB
RGD ID:8675644
Promoter ID:EPDNEW_M15853
Type:initiation region
Name:Nufip2_1
Description:Mus musculus nuclear fragile X mental retardation protein interactingprotein 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381177,686,139 - 77,686,199EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915814 AgrOrtholog
Ensembl Genes ENSMUSG00000037857 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000098365 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000137922 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000100802 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000181023 UniProtKB/Swiss-Prot
InterPro NUFIP2 UniProtKB/Swiss-Prot
KEGG Report mmu:68564 UniProtKB/Swiss-Prot
MGD MGI:1915814 ENTREZGENE
NCBI Gene 68564 ENTREZGENE
PANTHER PTHR28333 UniProtKB/Swiss-Prot
Pfam NUFIP2 UniProtKB/Swiss-Prot
PhenoGen Nufip2 PhenoGen
UniProt NUFP2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3TCE2 UniProtKB/Swiss-Prot
  Q3V195 UniProtKB/Swiss-Prot
  Q80TF1 UniProtKB/Swiss-Prot