Ube2dnl2 (ubiquitin-conjugating enzyme E2D N-terminal like 2) - Rat Genome Database

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Gene: Ube2dnl2 (ubiquitin-conjugating enzyme E2D N-terminal like 2) Mus musculus
Analyze
No known orthologs.
Symbol: Ube2dnl2
Name: ubiquitin-conjugating enzyme E2D N-terminal like 2
RGD ID: 1616710
MGI Page MGI
Description: Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Predicted to be involved in protein K48-linked ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus. Is expressed in dorsal root ganglion; heart ventricle; trigeminal ganglion; and ventral grey horn.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4930524E20Rik; hypothetical protein LOC75097; novel protein similar to ubiquitin-conjugating enzyme E2D 2 Ube2d2; ubiquitin-conjugating enzyme E2 D4; ubiquitin-conjugating enzyme E2D 2-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X113,817,279 - 113,818,207 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX113,817,279 - 113,818,207 (+)EnsemblGRCm39 Ensembl
GRCm38X114,907,582 - 114,908,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX114,907,582 - 114,908,510 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X112,021,191 - 112,022,119 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X112,021,191 - 112,022,119 (+)NCBIMGSCv36mm8
CeleraX101,689,603 - 101,690,427 (+)NCBICelera
Cytogenetic MapXE1NCBI
cM MapX49.47NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635  


Genomics

Variants

.
Variants in Ube2dnl2
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:52
Interacting mature miRNAs:54
Transcripts:ENSMUST00000062695
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse
11075102Modc2_mmodifier of Odc2 (mouse)X80189914114190059Mouse
4141803Lmr30_mleishmaniasis resistance 30 (mouse)Not determined85062606119062720Mouse
13208552Wght12_mweight 12 (mouse)X94043606149782996Mouse
13208556Lgth14_mbody length 14 (mouse)X94043606149782996Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000062695   ⟹   ENSMUSP00000059077
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX113,817,279 - 113,818,207 (+)Ensembl
GRCm38.p6 EnsemblX114,907,582 - 114,908,510 (+)Ensembl
RefSeq Acc Id: NM_001081661   ⟹   NP_001075130
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X113,817,279 - 113,818,207 (+)NCBI
GRCm38X114,907,582 - 114,908,510 (+)ENTREZGENE
MGSCv37X112,021,191 - 112,022,119 (+)RGD
CeleraX101,689,603 - 101,690,427 (+)RGD
cM MapX ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001075130 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL33430 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000059077
  ENSMUSP00000059077.2
Reference Protein Sequences
RefSeq Acc Id: NP_001075130   ⟸   NM_001081661
- UniProtKB: A2AFH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000059077   ⟸   ENSMUST00000062695
Protein Domains
UBC core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2AFH2-F1-model_v2 AlphaFold A2AFH2 1-155 view protein structure

Promoters
RGD ID:13681290
Promoter ID:EPDNEW_M24794
Type:initiation region
Name:Ube2dnl2_1
Description:Mus musculus ubiquitin-conjugating enzyme E2D N-terminal like2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X114,907,582 - 114,907,642EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922347 AgrOrtholog
Ensembl Genes ENSMUSG00000047079 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000062695 ENTREZGENE
  ENSMUST00000062695.2 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
InterPro UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_AS UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/TrEMBL
KEGG Report mmu:75097 UniProtKB/TrEMBL
MGD MGI:1922347 ENTREZGENE
NCBI Gene 75097 ENTREZGENE
PANTHER UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/TrEMBL
  UBIQUITIN-CONJUGATING ENZYME E2D N-TERMINAL-LIKE 1-RELATED UniProtKB/TrEMBL
Pfam UQ_con UniProtKB/TrEMBL
PhenoGen Ube2dnl2 PhenoGen
PROSITE UBIQUITIN_CONJUGAT_1 UniProtKB/TrEMBL
  UBIQUITIN_CONJUGAT_2 UniProtKB/TrEMBL
SMART UBCc UniProtKB/TrEMBL
Superfamily-SCOP UBQ-conjugat/RWD-like UniProtKB/TrEMBL
UniProt A2AFH2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-06-19 Ube2dnl2  ubiquitin-conjugating enzyme E2D N-terminal like 2  4930524E20Rik  RIKEN cDNA 4930524E20 gene  Symbol and/or name change 5135510 APPROVED