Gbx1 (gastrulation brain homeobox 1)

Gene: Gbx1 (gastrulation brain homeobox 1) Mus musculus

Analyze

Symbol:

Gbx1

Name:

gastrulation brain homeobox 1

RGD ID:

1616549

MGI Page

MGI

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within adult walking behavior; neuron differentiation; and proprioception. Located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; extraembryonic component; eye; and male reproductive gland or organ. Orthologous to human GBX1 (gastrulation brain homeobox 1).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

gastrulation and brain-specific homeobox protein 1; Gbx-1; homeobox protein GBX-1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GBX1 (gastrulation brain homeobox 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Gbx1 (gastrulation brain homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gbx1 (gastrulation brain homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GBX1 (gastrulation brain homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GBX1 (gastrulation brain homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gbx1 (gastrulation brain homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GBX1 (gastrulation brain homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GBX1 (gastrulation brain homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gbx1 (gastrulation brain homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Gbx1 (gastrulation brain homeobox 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GBX1 (gastrulation brain homeobox 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gbx1 (gastrulation brain homeobox 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	unpg	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	24,709,424 - 24,731,846 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	24,707,755 - 24,732,200 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	24,504,426 - 24,526,848 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	24,502,757 - 24,527,202 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	24,010,244 - 24,032,666 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	24,014,491 - 24,036,913 (-)	NCBI		MGSCv36	mm8
Celera	5	21,454,400 - 21,476,977 (-)	NCBI		Celera
Cytogenetic Map	5	A3	NCBI
cM Map	5	11.93	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

lethal congenital glycogen storage disease of heart (ISO)

long QT syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

chlorpyrifos (EXP)

glyphosate (ISO)

lipopolysaccharide (ISO)

mono(2-ethylhexyl) phthalate (EXP)

paracetamol (ISO)

PCB138 (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

testosterone (ISO)

trichloroethene (ISO)

triclosan (ISO)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult walking behavior (IMP)

neuron fate commitment (IMP)

proprioception (IMP)

regulation of DNA-templated transcription (IEA)

regulation of nervous system development (IBA)

regulation of transcription by RNA polymerase II (IBA)

sensory neuron axon guidance (IMP)

spinal cord motor neuron differentiation (IMP)

Cellular Component

nucleus (IBA,IDA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal behavior (IEA)

abnormal GABAergic neuron morphology (IAGP)

abnormal gait (IAGP)

abnormal locomotor activation (IAGP)

abnormal locomotor behavior (IAGP)

abnormal optic disk morphology (IEA)

abnormal proprioceptive neuron morphology (IAGP)

abnormal retina blood vessel morphology (IEA)

abnormal retina vasculature morphology (IEA)

decreased exploration in new environment (IEA)

decreased locomotor activity (IAGP)

decreased motor neuron number (IAGP)

enlarged urinary bladder (IEA)

impaired coordination (IAGP)

increased anxiety-related response (IAGP)

increased circulating alkaline phosphatase level (IEA)

increased nerve conduction velocity (IAGP)

increased thermal nociceptive threshold (IAGP)

increased thigmotaxis (IEA)

limb grasping (IEA)

no abnormal phenotype detected (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:1720547	PMID:7687285	PMID:7894155	PMID:9271679	PMID:11801365	PMID:12799077	PMID:12855770	PMID:14610273	PMID:14745958	PMID:15618518	PMID:16193514	PMID:16516881
PMID:16602821	PMID:17151600	PMID:17460091	PMID:17990271	PMID:18304314	PMID:18625066	PMID:19030180	PMID:19386638	PMID:20181579	PMID:21048141	PMID:21267068	PMID:21677750
PMID:21873635	PMID:23042297	PMID:23144817	PMID:23418536	PMID:24010020	PMID:24157949	PMID:24194600	PMID:24952961	PMID:26166575	PMID:26412852	PMID:27626380	PMID:27657450
PMID:27847324	PMID:31082736	PMID:32244588	PMID:33821423	PMID:33996801	PMID:35377797

Genomics

Comparative Map Data

Gbx1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	24,709,424 - 24,731,846 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	24,707,755 - 24,732,200 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	24,504,426 - 24,526,848 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	24,502,757 - 24,527,202 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	24,010,244 - 24,032,666 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	24,014,491 - 24,036,913 (-)	NCBI		MGSCv36	mm8
Celera	5	21,454,400 - 21,476,977 (-)	NCBI		Celera
Cytogenetic Map	5	A3	NCBI
cM Map	5	11.93	NCBI

GBX1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	151,148,009 - 151,167,694 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	151,148,009 - 151,174,745 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	150,845,096 - 150,864,781 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	150,476,609 - 150,495,800 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	145,403,014 - 145,422,208 (-)	NCBI		Celera
Cytogenetic Map	7	q36.1	NCBI
HuRef	7	144,657,212 - 144,676,250 (-)	NCBI		HuRef
CHM1_1	7	150,854,052 - 150,873,263 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	152,321,091 - 152,340,783 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	150,175,196 - 150,194,388 (-)	NCBI

Gbx1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	11,538,402 - 11,564,931 (+)	NCBI		GRCr8
mRatBN7.2	4	10,645,957 - 10,672,486 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	10,645,957 - 10,672,486 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	15,792,089 - 15,818,580 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	11,612,280 - 11,638,772 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	9,964,062 - 9,990,554 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	7,173,961 - 7,200,752 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	7,173,961 - 7,200,752 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	7,186,479 - 7,212,119 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	6,025,962 - 6,036,534 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	6,036,248 - 6,036,363 (+)	NCBI
Celera	4	6,262,522 - 6,287,235 (+)	NCBI		Celera
Cytogenetic Map	4	q11	NCBI

Gbx1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955491	5,575,836 - 5,592,804 (-)	NCBI	ChiLan1.0	ChiLan1.0

GBX1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	187,566,475 - 187,589,538 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	39,576,740 - 39,599,804 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	142,733,463 - 142,754,447 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	154,887,871 - 154,914,165 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	154,888,479 - 154,907,060 (-)	Ensembl	panpan1.1		panPan2

GBX1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	15,195,705 - 15,213,425 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	15,803,468 - 15,821,434 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	16,917,670 - 16,935,631 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	16,918,432 - 16,936,366 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	15,289,827 - 15,307,782 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	15,871,255 - 15,889,408 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	15,922,115 - 15,940,079 (-)	NCBI		UU_Cfam_GSD_1.0

Gbx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	6,321,299 - 6,339,067 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936527	6,566,306 - 6,582,130 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936527	6,566,306 - 6,582,130 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GBX1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	6,058,730 - 6,080,906 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	6,058,888 - 6,080,908 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	6,422,775 - 6,445,608 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GBX1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	119,331,203 - 119,354,622 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666072	15,302,028 - 15,322,785 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gbx1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624800	5,464,792 - 5,484,670 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gbx1
805 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	614
Count of miRNA genes:	441
Interacting mature miRNAs:	495
Transcripts:	ENSMUST00000088311
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12904958	Gmmq8_m	gastrocnemius muscle mass QTL 8 (mouse)					5	1	29421124	Mouse
10401122	Pgia41_m	proteoglycan induced arthritis 41 (mouse)			Not determined		5	823144	34823280	Mouse
15039371	Nmrs21_m	NAFLD-associated magnetic resonance shift 21 (mouse)					5	3504823	37504823	Mouse
1301806	Actd2_m	activity-distance traveled 2 (mouse)			Not determined		5	5384520	39384652	Mouse
4141207	Imrfq1_m	immune response to Factor IX QTL 1 (mouse)			Not determined		5	8124117	42124239	Mouse
7394748	Mom5_m	modifier of Min 5 (mouse)			Not determined		5	8847672	33475637	Mouse
1301693	Sle6_m	systemic lupus erythematosus susceptibility 6 (mouse)			Not determined		5	8890693	87841837	Mouse
1357478	Kdnw1_m	kidney weight 1 (mouse)			Not determined		5	8915949	40529869	Mouse
14696730	Kidlq1_m	kidney weight, left QTL 1 (mouse)					5	13563152	47563152	Mouse
1301685	Estq2_m	estradiol regulated response QTL 2 (mouse)			Not determined		5	15634084	49634190	Mouse
1300719	Iba5_m	induction of brown adipocytes 5 (mouse)			Not determined		5	20686993	54687134	Mouse
1301776	Skts3_m	skin tumor susceptibility 3 (mouse)			Not determined		5	21667295	55667403	Mouse
11537368	Hmtb10_m	hemostasis and thrombosis 10 (mouse)					5	22100823	54500318	Mouse
11537367	Hmtb11_m	hemostasis and thrombosis 11 (mouse)					5	22100823	64806579	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_015739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC120353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF547996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY319256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M81662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000088311 ⟹ ENSMUSP00000085651

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	5	24,707,755 - 24,732,200 (-)	Ensembl
GRCm38.p6 Ensembl	5	24,502,757 - 24,527,202 (-)	Ensembl

RefSeq Acc Id:

NM_015739 ⟹ NP_056554

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	5	24,709,424 - 24,731,846 (-)	NCBI
GRCm38	5	24,504,426 - 24,526,848 (-)	NCBI
MGSCv37	5	24,010,244 - 24,032,666 (-)	RGD
Celera	5	21,454,400 - 21,476,977 (-)	RGD
cM Map	5		ENTREZGENE

Sequence:

show sequence

GGAGCAAGTGAAGCGTAATTTGAGGAAGATGGATGAGTCCGGAGGGCGACACCCCCAACCCGCC
CGCCCGCCCCCTCCCTCCTTATGAGCGAGAGAGCGCGGCGCCGGAGCCACACTGCGCCGAGCCC
GCGCCCCGCCGCCACCTCGGCCCGCGCGCCCGCAGCGAGCCCTGCGTGTCCGCGCGGGGCGCAC
GGCGGGGCCCGGGCAGCGCCATGCAGAGAGCGGCAGGCGGCGGCGCCCCCGGGGGCAGCGGCGG
GAGCAGCGGCGGCCCCGGCGCCGCCTTCTCCATCGACTCGCTCATCGGGCCGCCGCCGCCGCGC
TCGGGCCACCTGCTCTACACCGGCTACCCCATGTTCATGCCCTACCGGCCGCTCGTGTTGCCGC
AGGCGCTGGCCCCCGCGCCGCTGCCCGCCGGCCTGCCGCCGCTCGCCCCGCTCGCCTCGTTCGC
CGGCCGCCTGAGCAATACCTTCTGCGCGGGGCTGGGCCAGGCGGTGCCCTCGATGGTGGCGCTG
ACCACTGCGCTGCCCAGCTTCGCAGAGCCCCCGGACGCCTACTACGGGCCCCCGGAGCTCGCCG
CCGCCGCCGCCTCCACCGCCTCGCGAAGCAACCCGGAGCCCGCGGCCCGGCGCACTGACGGAGC
GCTGGACGCTGAGGAGCTGCTGCCCGCGCGCGAGAAAGTGACTGAACCTCCGCCGCCCCCGCCT
CCGCACTTCTCTGAGACTTTCCCGAGTCTACCGGCAGAGGGGAAGGTGTACAGCTCAGATGAAG
AGAAGCTAGAGCCCCCAGCAGGAGACCCAGCAGGCAGCGAGCAGGAGGAAGAGGGCTCAGGCGG
TGACAGCGAGGACAGCTTCCTGGACAGTTCTGCAGGGGGCCCAGGGGCTCTTCTGGGACCTAAA
CCGAAGCTAAAGGGAAGCCCGGGGACTGGCGCTGAGGAGGGGACACCAGTGGCCACAGGGGTCA
CCACGCCTGGGGGGAAAAGCCGAAGGCGGCGCACAGCCTTCACCAGCGAGCAGCTTTTGGAGCT
GGAGAAGGAGTTTCACTGCAAGAAATACCTGAGTCTGACAGAGCGCTCCCAGATCGCCCACGCC
CTCAAGCTCAGTGAGGTGCAGGTGAAGATCTGGTTTCAGAACCGCCGGGCCAAGTGGAAGCGCA
TCAAGGCTGGCAATGTGAGCAGTCGTTCTGGGGAGCCGGTGAGAAACCCCAAGATTGTAGTGCC
CATACCTGTGCACGTCAACAGGTTTGCTGTGCGCAGCCAGCACCAACAGATGGAGCAAGGAGCC
CGGCCCTGACCGAGCTCCCCGGACCGGAAGTCACAGGATCTGAACCTGTGGCCGCCCAAGACTC
ACTGGGTACTGCAGCCTAGAGGGGCCTGTTGAACCCTGCTCCGGGAGAGGCCAGCGTATTCCCG
GGACACAAGACTATTTGGCCTGAGACTGTTCTAGAGACCTCAGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_056554	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA63311	(Get FASTA)	NCBI Sequence Viewer
	AAO16238	(Get FASTA)	NCBI Sequence Viewer
	AAQ19677	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000085651
	ENSMUSP00000085651.5
GenBank Protein	P82976	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_056554 ⟸ NM_015739

- UniProtKB:

Q8CGW5 (UniProtKB/Swiss-Prot), P82976 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MSPEGDTPNPPARPLPPYERESAAPEPHCAEPAPRRHLGPRARSEPCVSARGARRGPGSAMQRA
AGGGAPGGSGGSSGGPGAAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQALAPAPLPAG
LPPLAPLASFAGRLSNTFCAGLGQAVPSMVALTTALPSFAEPPDAYYGPPELAAAAASTASRSN
PEPAARRTDGALDAEELLPAREKVTEPPPPPPPHFSETFPSLPAEGKVYSSDEEKLEPPAGDPA
GSEQEEEGSGGDSEDSFLDSSAGGPGALLGPKPKLKGSPGTGAEEGTPVATGVTTPGGKSRRRR
TAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRSG
EPVRNPKIVVPIPVHVNRFAVRSQHQQMEQGARP

hide sequence

RefSeq Acc Id:

ENSMUSP00000085651 ⟸ ENSMUST00000088311

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P82976-F1-model_v2	AlphaFold	P82976	1-418	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:95667	AgrOrtholog
Ensembl Genes	ENSMUSG00000067724	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000088311	ENTREZGENE
	ENSMUST00000088311.6	UniProtKB/Swiss-Prot
Gene3D-CATH	Homeodomain-like	UniProtKB/Swiss-Prot
InterPro	GBX-1/2	UniProtKB/Swiss-Prot
	Homeobox-like_sf	UniProtKB/Swiss-Prot
	Homeobox_CS	UniProtKB/Swiss-Prot
	Homeobox_dom	UniProtKB/Swiss-Prot
	Homeobox_metazoa	UniProtKB/Swiss-Prot
KEGG Report	mmu:231044	UniProtKB/Swiss-Prot
MGD	MGI:95667	ENTREZGENE
NCBI Gene	231044	ENTREZGENE
PANTHER	PTHR24334	UniProtKB/Swiss-Prot
	PTHR24334:SF2	UniProtKB/Swiss-Prot
Pfam	Homeodomain	UniProtKB/Swiss-Prot
PhenoGen	Gbx1	PhenoGen
PRINTS	HOMEOBOX	UniProtKB/Swiss-Prot
PROSITE	HOMEOBOX_1	UniProtKB/Swiss-Prot
	HOMEOBOX_2	UniProtKB/Swiss-Prot
SMART	HOX	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46689	UniProtKB/Swiss-Prot
UniProt	GBX1_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8CGW5	ENTREZGENE
UniProt Secondary	Q8CGW5	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Mammalian Phenotype