Gene: Esyt3 (extended synaptotagmin-like protein 3) Mus musculus
Analyze
Symbol:
Esyt3
Name:
extended synaptotagmin-like protein 3
Description:
ENCODES a protein that exhibits lipid binding (inferred); metal ion binding (inferred); INVOLVED IN endoplasmic reticulum-plasma membrane tethering (inferred); lipid transport (inferred); ASSOCIATED WITH decreased cell migration; increased cellular sensitivity to oxidative stress; increased sensitivity to induced cell death; FOUND IN endoplasmic reticulum-plasma membrane contact site (ortholog); extrinsic component of cytoplasmic side of plasma membrane (ortholog); integral component of plasma membrane (ortholog); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
D930024E11; D9Ertd280e; E-Syt3; extended synaptotagmin-3; Fam62c; family with sequence similarity 62 (C2 domain containing), member C; family with sequence similarity 62, member C; KIAA4186; mKIAA4186
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ESYT3 (extended synaptotagmin 3) HGNC
Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Esyt3 (extended synaptotagmin 3) HGNC
Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Esyt3 (extended synaptotagmin 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ESYT3 (extended synaptotagmin 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ESYT3 (extended synaptotagmin 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Esyt3 (extended synaptotagmin 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ESYT3 (extended synaptotagmin 3) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Esyt3 (extended synaptotagmin 3)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
ESYT3 (extended synaptotagmin 3)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
esyt3 (extended synaptotagmin-like protein 3)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, ZFIN)
Drosophila melanogaster (fruit fly):
Esyt2
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Saccharomyces cerevisiae (baker's yeast):
TCB1
Alliance
DIOPT (Hieranoid, InParanoid, OrthoFinder, PhylomeDB, Roundup)
Saccharomyces cerevisiae (baker's yeast):
TCB2
Alliance
DIOPT (Hieranoid, InParanoid, OrthoFinder, Roundup)
Saccharomyces cerevisiae (baker's yeast):
TCB3
Alliance
DIOPT (Hieranoid, InParanoid, PhylomeDB, Roundup)
Caenorhabditis elegans (roundworm):
esyt-2
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 9 99,309,963 - 99,360,159 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 9 99,210,386 - 99,258,949 (-) NCBI GRCm37 mm9 NCBIm37 MGSCv36 9 99,119,495 - 99,167,882 (-) NCBI mm8 Celera 9 98,843,495 - 98,893,869 (-) NCBI Celera Cytogenetic Map 9 E3.3 NCBI cM Map 9 51.54 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Gene-Chemical Interaction Annotations
17beta-estradiol affects expression ISO RGD:1605327 6480464 Estradiol affects the expression of ESYT3 mRNA CTD PMID:22574217 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ESYT3 promoter] CTD PMID:19654925 2-hydroxypropanoic acid decreases expression ISO RGD:1605327 6480464 Lactic Acid results in decreased expression of ESYT3 mRNA CTD PMID:30851411 aflatoxin B1 increases methylation ISO RGD:1605327 6480464 Aflatoxin B1 results in increased methylation of ESYT3 gene CTD PMID:27153756 amosite asbestos increases expression EXP 6480464 Asbestos, Amosite results in increased expression of ESYT3 mRNA CTD PMID:23917077 arsenite(3-) increases methylation ISO RGD:1605327 6480464 arsenite results in increased methylation of ESYT3 promoter CTD PMID:23974009 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of ESYT3 mRNA CTD PMID:22228805 Benzo[k]fluoranthene decreases expression EXP 6480464 benzo(k)fluoranthene results in decreased expression of ESYT3 mRNA CTD PMID:26377693 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ESYT3 mRNA CTD PMID:26063408 bisphenol A affects expression ISO RGD:1561304 6480464 bisphenol A affects the expression of ESYT3 mRNA CTD PMID:25181051 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of ESYT3 mRNA, Nanotubes, Carbon results in decreased expression of ESYT3 mRNA CTD PMID:25554681 copper atom increases expression ISO RGD:1561304 6480464 Copper deficiency results in increased expression of ESYT3 mRNA CTD PMID:26033743 copper(0) increases expression ISO RGD:1561304 6480464 Copper deficiency results in increased expression of ESYT3 mRNA CTD PMID:26033743 copper(2+) increases expression ISO RGD:1561304 6480464 Copper deficiency results in increased expression of ESYT3 mRNA CTD PMID:26033743 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of ESYT3 mRNA CTD PMID:21266533 dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ESYT3 mRNA CTD PMID:30529165 dorsomorphin multiple interactions ISO RGD:1605327 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ESYT3 mRNA CTD PMID:27188386 entinostat multiple interactions ISO RGD:1605327 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ESYT3 mRNA CTD PMID:27188386 entinostat increases expression ISO RGD:1605327 6480464 entinostat results in increased expression of ESYT3 mRNA CTD PMID:26272509 fonofos increases methylation ISO RGD:1605327 6480464 Fonofos results in increased methylation of ESYT3 promoter CTD PMID:22847954 nickel atom decreases expression ISO RGD:1605327 6480464 Nickel results in decreased expression of ESYT3 mRNA CTD PMID:24768652 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of ESYT3 mRNA CTD PMID:17562736 parathion increases methylation ISO RGD:1605327 6480464 Parathion results in increased methylation of ESYT3 promoter CTD PMID:22847954 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ESYT3 mRNA CTD PMID:18301758 rac-lactic acid decreases expression ISO RGD:1605327 6480464 Lactic Acid results in decreased expression of ESYT3 mRNA CTD PMID:30851411 SB 431542 multiple interactions ISO RGD:1605327 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ESYT3 mRNA CTD PMID:27188386 terbufos increases methylation ISO RGD:1605327 6480464 terbufos results in increased methylation of ESYT3 promoter CTD PMID:22847954 urethane increases expression ISO RGD:1605327 6480464 Urethane results in increased expression of ESYT3 mRNA CTD PMID:28818685 valproic acid increases methylation ISO RGD:1605327 6480464 Valproic Acid results in increased methylation of ESYT3 gene CTD PMID:29154799 valproic acid increases expression ISO RGD:1605327 6480464 Valproic Acid results in increased expression of ESYT3 mRNA CTD PMID:23179753
Gene Ontology Annotations
Gene Ontology Annotations
