Chd7 (chromodomain helicase DNA binding protein 7) - Rat Genome Database
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Gene: Chd7 (chromodomain helicase DNA binding protein 7) Mus musculus
Analyze
Symbol: Chd7
Name: chromodomain helicase DNA binding protein 7
RGD ID: 1616427
MGI Page MGI
Description: Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and promoter-specific chromatin binding activity. Involved in several processes, including adult walking behavior; animal organ development; and nervous system development. Localizes to nucleus. Is expressed in several structures, including alimentary system; central nervous system; cranial nerve; lung; and sensory organ. Used to study CHARGE syndrome. Human ortholog(s) of this gene implicated in CHARGE syndrome; hypogonadotropic hypogonadism 5 with or without anosmia; and idiopathic scoliosis. Orthologous to human CHD7 (chromodomain helicase DNA binding protein 7).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A730019I05Rik; ATP-dependent helicase CHD7; CHD-7; chromodomain-helicase-DNA-binding protein 7; Cy; Cyc; Cycn; Cyn; Dz; Edy; F; Flo; GENA 47; Gena 52; GENA 60; L; Lda; metis; Mt; Ob; Obt; RP23-464N23.1; To; Todo; WBE1; Wh; Whi
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3948,690,345 - 8,868,449 (+)NCBIGRCm39mm39
GRCm3848,690,402 - 8,868,449 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl48,690,406 - 8,867,659 (+)EnsemblGRCm38mm10GRCm38
MGSCv3748,618,068 - 8,793,957 (+)NCBIGRCm37mm9NCBIm37
MGSCv3648,617,551 - 8,793,957 (+)NCBImm8
Celera48,587,948 - 8,703,577 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult heart development  (IMP)
adult walking behavior  (IMP)
aorta development  (IMP)
aorta morphogenesis  (IMP)
artery morphogenesis  (IGI)
atrioventricular canal development  (IMP)
blood circulation  (IMP)
blood vessel development  (IMP)
blood vessel remodeling  (IMP)
camera-type eye development  (IMP)
cardiac septum morphogenesis  (IMP)
central nervous system development  (ISO)
chromatin organization  (IEA)
chromatin remodeling  (IMP)
cognition  (ISO)
cranial nerve development  (ISO)
ear morphogenesis  (IMP)
embryonic hindlimb morphogenesis  (IMP)
epithelium development  (IMP)
face development  (ISO)
female genitalia development  (IMP)
genitalia development  (ISO)
heart morphogenesis  (IMP,ISO)
in utero embryonic development  (IMP,ISO)
inner ear morphogenesis  (IMP,ISO)
innervation  (IMP)
limb development  (ISO)
locomotory behavior  (IMP)
nose development  (IMP,ISO)
olfactory behavior  (IMP)
olfactory bulb development  (IMP)
olfactory nerve development  (IMP)
positive regulation of multicellular organism growth  (IMP)
positive regulation of transcription by RNA polymerase II  (IMP)
regulation of growth hormone secretion  (ISO)
regulation of neurogenesis  (IMP)
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum  (IMP)
response to bacterium  (IEP)
retina development in camera-type eye  (ISO)
right ventricular compact myocardium morphogenesis  (IMP)
roof of mouth development  (IMP)
rRNA processing  (IEA)
secondary palate development  (ISO)
semicircular canal morphogenesis  (IGI)
sensory perception of sound  (IMP)
skeletal system development  (ISO)
T cell differentiation  (ISO)
tissue remodeling  (IMP)
ventricular trabecula myocardium morphogenesis  (IMP)

Cellular Component
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IDA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal auditory tube morphology  (IAGP)
abnormal behavior  (IEA)
abnormal brain development  (IAGP)
abnormal cardiac outflow tract development  (IAGP)
abnormal cochlea morphology  (IAGP)
abnormal common carotid artery morphology  (IAGP)
abnormal common crus morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal cranial nerve morphology  (IAGP)
abnormal crista ampullaris morphology  (IAGP)
abnormal crista ampullaris neuroepithelium morphology  (IAGP)
abnormal digit development  (IAGP)
abnormal distortion product otoacoustic emission  (IAGP)
abnormal ear development  (IAGP)
abnormal embryonic neuroepithelium morphology  (IAGP)
abnormal epigenetic regulation of gene expression  (IAGP)
abnormal external female genitalia morphology  (IAGP)
abnormal eye development  (IAGP)
abnormal eye morphology  (IAGP)
abnormal fourth pharyngeal arch artery morphology  (IAGP)
abnormal frontal lobe morphology  (IAGP)
abnormal glenoid fossa morphology  (IAGP)
abnormal hindlimb morphology  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal incudomalleolar joint morphology  (IAGP)
abnormal incus long process morphology  (IAGP)
abnormal incus morphology  (IAGP)
abnormal incus short process morphology  (IAGP)
abnormal inner ear canal fusion  (IAGP)
abnormal inner ear vestibule morphology  (IAGP)
abnormal internal nares morphology  (IAGP)
abnormal lateral semicircular canal morphology  (IAGP)
abnormal lens development  (IAGP)
abnormal malleus manubrium morphology  (IAGP)
abnormal malleus morphology  (IAGP)
abnormal maternal nurturing  (IAGP)
abnormal middle ear epithelium morphology  (IAGP)
abnormal middle ear ossicle morphology  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal nasal pit morphology  (IAGP)
abnormal neocortex morphology  (IAGP)
abnormal neural crest cell migration  (IAGP)
abnormal neuronal precursor cell number  (IAGP)
abnormal neuronal precursor proliferation  (IAGP)
abnormal olfactory lobe morphology  (IAGP)
abnormal optic cup morphology  (IAGP)
abnormal optic eminence morphology  (IAGP)
abnormal otic vesicle development  (IAGP)
abnormal outer ear morphology  (IAGP)
abnormal oval window morphology  (IAGP)
abnormal parietal lobe morphology  (IAGP)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal placing response  (IAGP)
abnormal posterior semicircular canal morphology  (IAGP)
abnormal pulmonary trunk morphology  (IAGP)
abnormal round window morphology  (IAGP)
abnormal secondary palate development  (IAGP)
abnormal semicircular canal morphology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal sixth pharyngeal arch artery morphology  (IAGP)
abnormal stapes crus morpholgy  (IAGP)
abnormal stapes footplate morphology  (IAGP)
abnormal stapes head morphology  (IAGP)
abnormal stapes morphology  (IAGP)
abnormal stationary movement  (IAGP)
abnormal subclavian artery morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal superior semicircular canal morphology  (IAGP)
abnormal telencephalon development  (IAGP)
abnormal telencephalon morphology  (IAGP)
abnormal trigeminal ganglion morphology  (IAGP)
abnormal vagus nerve morphology  (IAGP)
abnormal vestibular nerve morphology  (IAGP)
abnormal vestibulocochlear ganglion morphology  (IAGP)
absent cochlear microphonics  (IAGP)
absent fourth pharyngeal arch artery  (IAGP)
absent hippocampus  (IAGP)
absent lateral semicircular canal  (IAGP)
absent olfactory bulb  (IAGP)
absent optic cup  (IAGP)
absent posterior semicircular canal  (IAGP)
absent utricle  (IAGP)
absent vestibular saccule  (IAGP)
aorta coarctation  (IAGP)
aortic arch coarctation  (IAGP)
atrioventricular cushion hypoplasia  (IAGP)
bidirectional circling  (IAGP)
blepharitis  (IAGP)
circling  (IAGP)
cleft secondary palate  (IAGP)
clitoris hypoplasia  (IAGP)
coloboma  (IAGP)
conjunctivitis  (IAGP)
decreased body length  (IEA)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased cochlear coiling  (IAGP)
decreased cochlear nerve compound action potential  (IAGP)
decreased embryonic neuroepithelium thickness  (IAGP)
decreased fetal cardiomyocyte proliferation  (IAGP)
decreased lateral semicircular canal size  (IAGP)
decreased lumbar vertebrae number  (IEA)
decreased palatal rugae number  (IAGP)
decreased posterior semicircular canal size  (IAGP)
decreased startle reflex  (IAGP)
decreased superior semicircular canal size  (IAGP)
decreased total body fat amount  (IAGP)
delayed embryo turning  (IAGP)
dilated lateral ventricles  (IAGP)
dilated third ventricle  (IAGP)
dry eyes  (IAGP)
ectopic thymus  (IAGP)
edema  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
eyelid edema  (IAGP)
facial asymmetry  (IAGP)
fusion of glossopharyngeal and vagus nerve  (IAGP)
head bobbing  (IAGP)
head shaking  (IAGP)
head tossing  (IAGP)
hemorrhage  (IAGP)
hydrocephaly  (IAGP)
hyperactivity  (IAGP)
impaired hearing  (IAGP)
impaired righting response  (IAGP)
impaired swimming  (IAGP)
increased cardiomyocyte apoptosis  (IAGP)
increased cochlear inner hair cell number  (IAGP)
increased cochlear outer hair cell number  (IAGP)
increased cranium height  (IAGP)
increased middle ear goblet cell number  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased periosteum thickness  (IAGP)
increased susceptibility to otitis media  (IAGP)
interrupted aortic arch  (IAGP)
keratoconjunctivitis sicca  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
long snout  (IAGP)
narrow eye opening  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
ocular hypertelorism  (IAGP)
otosclerosis  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
Rathke's pouch hypoplasia  (IAGP)
reduced female fertility  (IAGP)
reduced fertility  (IAGP)
reduced male fertility  (IAGP)
short snout  (IAGP)
small endolymphatic duct  (IAGP)
small hippocampus  (IAGP)
small lens  (IAGP)
small olfactory bulb  (IAGP)
small otic vesicle  (IAGP)
small stapes obturator foramen  (IAGP)
small thymus  (IAGP)
thin myocardium  (IAGP)
thymus hypoplasia  (IAGP)
ventricular septal defect  (IAGP)
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10512203   PMID:10922068   PMID:10932191   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:11919684   PMID:12466851   PMID:12477932  
PMID:12520002   PMID:14610273   PMID:14691545   PMID:15353999   PMID:15782199   PMID:15840001   PMID:15916118   PMID:16104381   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17334657  
PMID:17701983   PMID:17967808   PMID:18554416   PMID:18799693   PMID:18973680   PMID:19251738   PMID:19279158   PMID:19809474   PMID:19855134   PMID:20507341   PMID:20591827   PMID:20657823  
PMID:20736290   PMID:21267068   PMID:21532573   PMID:21596839   PMID:21677750   PMID:21875659   PMID:22539951   PMID:22658483   PMID:22705977   PMID:23012479   PMID:23285124   PMID:23319608  
PMID:23827709   PMID:23892456   PMID:24026680   PMID:24293546   PMID:24368733   PMID:24457600   PMID:24728844   PMID:24975120   PMID:25119037   PMID:25183173   PMID:25859222   PMID:25985275  
PMID:26102480   PMID:26584622   PMID:26670829   PMID:26928066   PMID:27174565   PMID:27955690   PMID:28165338   PMID:28317875   PMID:28373172   PMID:28671696   PMID:28931573   PMID:29018080  
PMID:29168327   PMID:29212025   PMID:29311329   PMID:29467333   PMID:30108144   PMID:30595499   PMID:31444215   PMID:32325033   PMID:32883883   PMID:33127760  


Genomics

Comparative Map Data
Chd7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3948,690,345 - 8,868,449 (+)NCBIGRCm39mm39
GRCm3848,690,402 - 8,868,449 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl48,690,406 - 8,867,659 (+)EnsemblGRCm38mm10GRCm38
MGSCv3748,618,068 - 8,793,957 (+)NCBIGRCm37mm9NCBIm37
MGSCv3648,617,551 - 8,793,957 (+)NCBImm8
Celera48,587,948 - 8,703,577 (+)NCBICelera
Cytogenetic Map4A1NCBI
cM Map43.68NCBI
CHD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl860,678,740 - 60,868,028 (+)EnsemblGRCh38hg38GRCh38
GRCh38860,678,740 - 60,868,028 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37861,591,321 - 61,780,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36861,753,893 - 61,942,019 (+)NCBINCBI36hg18NCBI36
Celera857,580,946 - 57,769,196 (+)NCBI
Cytogenetic Map8q12.2NCBI
HuRef857,078,404 - 57,267,234 (+)NCBIHuRef
CHM1_1861,643,239 - 61,832,394 (+)NCBICHM1_1
Chd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0521,769,087 - 21,952,036 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl521,830,882 - 21,950,696 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0526,520,706 - 26,702,242 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4522,549,237 - 22,710,257 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1522,591,442 - 22,710,257 (+)NCBI
Celera521,141,679 - 21,262,470 (+)NCBICelera
Cytogenetic Map5q13NCBI
Chd7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544417,858,771 - 18,067,248 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544417,859,999 - 18,067,623 (-)NCBIChiLan1.0ChiLan1.0
CHD7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1858,816,836 - 58,945,186 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl858,816,840 - 58,945,186 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0857,091,002 - 57,282,471 (+)NCBIMhudiblu_PPA_v0panPan3
CHD7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2911,156,340 - 11,283,627 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12911,115,865 - 11,284,713 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Chd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649612,381,225 - 12,505,121 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHD7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl472,571,874 - 72,754,432 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1472,572,455 - 72,754,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2479,030,873 - 79,152,740 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHD7
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1856,654,939 - 56,782,803 (+)NCBI
ChlSab1.1 Ensembl856,657,826 - 56,785,804 (+)Ensembl
Chd7
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474431,103,053 - 31,302,314 (-)NCBI

Position Markers
Chd7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4A1UniSTS
cM Map41.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301274Lmr9_mleishmaniasis resistance 9 (mouse)Not determined4120657234Mouse
11049579Lmr9b_mleishmaniasis resistance 9b (mouse)4120657234Mouse
11049580Lmr9a_mleishmaniasis resistance 9 (mouse)4120657234Mouse
10412079Sm1_msusceptibility to Schistosoma mansoni infection 1 (mouse)Not determined4122955614Mouse
1301510Bbaa13_mB.burgdorferi-associated arthritis 13 (mouse)Not determined4126395649Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1101
Count of miRNA genes:489
Interacting mature miRNAs:595
Transcripts:ENSMUST00000039267, ENSMUST00000051558, ENSMUST00000127476, ENSMUST00000129655, ENSMUST00000130709, ENSMUST00000170391, ENSMUST00000170457
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001277149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003954972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK035953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL805903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD540105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ102897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN717040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000039267   ⟹   ENSMUSP00000043903
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl48,690,921 - 8,866,810 (+)Ensembl
RefSeq Acc Id: ENSMUST00000051558   ⟹   ENSMUSP00000059079
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl48,691,365 - 8,867,659 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127476   ⟹   ENSMUSP00000118711
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl48,690,470 - 8,785,591 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129655   ⟹   ENSMUSP00000123241
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl48,710,340 - 8,751,562 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130709
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl48,840,322 - 8,844,721 (+)Ensembl
RefSeq Acc Id: ENSMUST00000170391   ⟹   ENSMUSP00000127007
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl48,751,438 - 8,867,224 (+)Ensembl
RefSeq Acc Id: ENSMUST00000170457
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl48,690,406 - 8,755,906 (+)Ensembl
RefSeq Acc Id: ENSMUST00000222546   ⟹   ENSMUSP00000152166
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl48,855,231 - 8,858,618 (+)Ensembl
RefSeq Acc Id: NM_001277149   ⟹   NP_001264078
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,406 - 8,868,449 (+)NCBI
GRCm3848,690,406 - 8,868,449 (+)NCBI
Celera48,587,958 - 8,705,208 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001355382   ⟹   NP_001342311
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,751,324 - 8,868,449 (+)NCBI
GRCm3848,751,324 - 8,868,449 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538004   ⟹   XP_006538067
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,691,075 - 8,867,652 (+)NCBI
GRCm3848,691,258 - 8,867,654 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538005   ⟹   XP_006538068
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,345 - 8,867,654 (+)NCBI
GRCm3848,690,402 - 8,867,654 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006538006   ⟹   XP_006538069
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,785,446 - 8,867,654 (+)NCBI
GRCm3848,785,446 - 8,867,654 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003954972
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,345 - 8,864,283 (+)NCBI
GRCm3848,690,402 - 8,864,034 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004941924
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,345 - 8,866,797 (+)NCBI
RefSeq Acc Id: XR_004941925
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3948,690,345 - 8,864,289 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001264078   ⟸   NM_001277149
- Peptide Label: isoform 1
- UniProtKB: A2AJK6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006538068   ⟸   XM_006538005
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006538067   ⟸   XM_006538004
- Peptide Label: isoform X1
- UniProtKB: A2AJK6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006538069   ⟸   XM_006538006
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001342311   ⟸   NM_001355382
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000127007   ⟸   ENSMUST00000170391
RefSeq Acc Id: ENSMUSP00000152166   ⟸   ENSMUST00000222546
RefSeq Acc Id: ENSMUSP00000059079   ⟸   ENSMUST00000051558
RefSeq Acc Id: ENSMUSP00000118711   ⟸   ENSMUST00000127476
RefSeq Acc Id: ENSMUSP00000123241   ⟸   ENSMUST00000129655
RefSeq Acc Id: ENSMUSP00000043903   ⟸   ENSMUST00000039267
Promoters
RGD ID:6835056
Promoter ID:MM_KWN:36616
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000039267,   ENSMUST00000051558,   UC008RXY.1,   UC008RXZ.1,   UC008RYB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3648,617,141 - 8,618,402 (+)MPROMDB
RGD ID:6835054
Promoter ID:MM_KWN:36617
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Spleen
Transcripts:OTTMUST00000010007
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3648,636,521 - 8,637,882 (+)MPROMDB
RGD ID:6882778
Promoter ID:EPDNEW_M4840
Type:initiation region
Name:Chd7_1
Description:Mus musculus chromodomain helicase DNA binding protein 7 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4841  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3848,690,437 - 8,690,497EPDNEW
RGD ID:6882780
Promoter ID:EPDNEW_M4841
Type:single initiation site
Name:Chd7_2
Description:Mus musculus chromodomain helicase DNA binding protein 7 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4840  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3848,714,444 - 8,714,504EPDNEW
RGD ID:6835055
Promoter ID:MM_KWN:36618
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000010008
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3648,766,476 - 8,766,976 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444748 AgrOrtholog
Ensembl Genes ENSMUSG00000041235 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000043903 UniProtKB/Swiss-Prot
  ENSMUSP00000059079 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000118711 UniProtKB/TrEMBL
  ENSMUSP00000123241 UniProtKB/TrEMBL
  ENSMUSP00000127007 UniProtKB/TrEMBL
  ENSMUSP00000152166 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000039267 UniProtKB/Swiss-Prot
  ENSMUST00000051558 UniProtKB/Swiss-Prot
  ENSMUST00000127476 UniProtKB/TrEMBL
  ENSMUST00000129655 UniProtKB/TrEMBL
  ENSMUST00000170391 UniProtKB/TrEMBL
  ENSMUST00000222546 UniProtKB/TrEMBL
Gene3D-CATH 2.20.28.130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/Swiss-Prot
InterPro BRK_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BRK_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CHD9 UniProtKB/TrEMBL
  Chromo-like_dom_sf UniProtKB/Swiss-Prot
  Chromo/chromo_shadow_dom UniProtKB/Swiss-Prot
  Chromo_domain UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  SNF2-like_sf UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
KEGG Report mmu:320790 UniProtKB/Swiss-Prot
MGD MGI:2444748 ENTREZGENE
NCBI Gene 320790 ENTREZGENE
PANTHER PTHR46850 UniProtKB/TrEMBL
Pfam BRK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chromo UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  SNF2_N UniProtKB/Swiss-Prot
PhenoGen Chd7 PhenoGen
PROSITE CHROMO_2 UniProtKB/Swiss-Prot
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
SMART BRK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CHROMO UniProtKB/Swiss-Prot
  DEXDc UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF160481 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot
  SSF54160 UniProtKB/Swiss-Prot
UniGene Mm.138792 ENTREZGENE
UniProt A0A0R4J1U9_MOUSE UniProtKB/TrEMBL
  A0A1Y7VIV0_MOUSE UniProtKB/TrEMBL
  A2AJK6 ENTREZGENE
  A2AJK7_MOUSE UniProtKB/TrEMBL
  CHD7_MOUSE UniProtKB/Swiss-Prot
  E9PV74_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TA86 UniProtKB/Swiss-Prot
  Q3TAG7 UniProtKB/Swiss-Prot
  Q3TBU4 UniProtKB/Swiss-Prot
  Q8C986 UniProtKB/Swiss-Prot
  Q8K244 UniProtKB/Swiss-Prot