Frem1 (Fras1 related extracellular matrix protein 1) - Rat Genome Database

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Gene: Frem1 (Fras1 related extracellular matrix protein 1) Mus musculus
Analyze
Symbol: Frem1
Name: Fras1 related extracellular matrix protein 1
RGD ID: 1616422
MGI Page MGI
Description: Predicted to have carbohydrate binding activity and metal ion binding activity. Involved in cell-matrix adhesion. Localizes to basement membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and skin. Used to study Fraser syndrome; chromosome 9p deletion syndrome; and congenital diaphragmatic hernia. Human ortholog(s) of this gene implicated in congenital diaphragmatic hernia. Orthologous to human FREM1 (FRAS1 related extracellular matrix 1); INTERACTS WITH 1,1-dichloroethene; 4,4'-sulfonyldiphenol; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC037594; crf1; crf11; D430009N09; D630008K06; eye; eyes; eyes2; FRAS1-related extracellular matrix protein 1; heb; QBRI; qbrick
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39482,816,157 - 82,970,743 (-)NCBIGRCm39mm39
GRCm39 Ensembl482,816,157 - 82,970,576 (-)Ensembl
GRCm38482,897,920 - 83,052,506 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl482,897,920 - 83,052,339 (-)EnsemblGRCm38mm10GRCm38
MGSCv37482,543,831 - 82,667,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv36482,369,158 - 82,492,333 (-)NCBImm8
Celera481,433,285 - 81,556,740 (-)NCBICelera
Cytogenetic Map4C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anogenital distance  (IAGP)
abnormal brain morphology  (IAGP)
abnormal conjunctiva morphology  (IAGP)
abnormal cornea morphology  (IAGP)
abnormal cranial suture morphology  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal diaphragm development  (IAGP)
abnormal digit morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal eye development  (IAGP)
abnormal eye morphology  (IAGP)
abnormal gallbladder morphology  (IAGP)
abnormal internasal suture morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal maxillary-premaxillary suture morphology  (IAGP)
abnormal metopic suture morphology  (IAGP)
abnormal midface morphology  (IAGP)
abnormal nasal bone morphology  (IAGP)
abnormal postnatal growth/weight/body size  (IEA)
abnormal retina morphology  (IAGP)
absent corneal epithelium  (IAGP)
absent eyelids  (IAGP)
absent kidney  (IAGP)
anophthalmia  (IAGP)
asymmetric snout  (IAGP)
bleb  (IAGP)
blistering  (IAGP)
broad nasal bone  (IAGP)
coloboma  (IAGP)
cryptophthalmos  (IAGP)
decreased cornea thickness  (IAGP)
diaphragmatic hernia  (IAGP)
early eyelid opening  (IEA)
eyelids fail to open  (IEA)
eyelids open at birth  (IAGP)
fused right lung lobes  (IAGP)
increased inner canthal distance  (IAGP)
microphthalmia  (IAGP)
midface hypoplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
polydactyly  (IAGP)
premature metopic suture closure  (IAGP)
prenatal lethality, incomplete penetrance  (IEA)
preweaning lethality, incomplete penetrance  (IAGP)
rectal prolapse  (IAGP)
short philtrum  (IAGP)
short snout  (IAGP)
single kidney  (IAGP)
syndactyly  (IAGP)
trigonocephaly  (IAGP)
References

Additional References at PubMed
PMID:6391574   PMID:6793660   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12955145   PMID:14730302   PMID:15345741   PMID:15489334  
PMID:15878328   PMID:16141072   PMID:16141073   PMID:16466971   PMID:16880404   PMID:17240369   PMID:17251066   PMID:17462874   PMID:17596926   PMID:18563433   PMID:18757743   PMID:19732862  
PMID:19940113   PMID:20843830   PMID:21267068   PMID:22159717   PMID:22613833   PMID:24046351   PMID:25859222   PMID:26952977   PMID:27856617   PMID:29618029  


Genomics

Comparative Map Data
Frem1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39482,816,157 - 82,970,743 (-)NCBIGRCm39mm39
GRCm39 Ensembl482,816,157 - 82,970,576 (-)Ensembl
GRCm38482,897,920 - 83,052,506 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl482,897,920 - 83,052,339 (-)EnsemblGRCm38mm10GRCm38
MGSCv37482,543,831 - 82,667,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv36482,369,158 - 82,492,333 (-)NCBImm8
Celera481,433,285 - 81,556,740 (-)NCBICelera
Cytogenetic Map4C3NCBI
FREM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl914,737,152 - 14,910,995 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl914,734,666 - 14,910,995 (-)EnsemblGRCh38hg38GRCh38
GRCh38914,734,666 - 14,911,653 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37914,737,150 - 14,910,993 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36914,727,150 - 14,900,234 (-)NCBINCBI36hg18NCBI36
Build 34914,727,154 - 14,900,993NCBI
Celera914,668,102 - 14,844,502 (-)NCBI
Cytogenetic Map9p22.3NCBI
HuRef914,697,961 - 14,874,294 (-)NCBIHuRef
CHM1_1914,734,708 - 14,910,773 (-)NCBICHM1_1
Frem1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2597,321,275 - 97,469,523 (-)NCBI
Rnor_6.0 Ensembl5101,020,448 - 101,166,651 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05101,018,009 - 101,166,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05105,039,872 - 105,188,547 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45101,773,603 - 101,891,178 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15101,778,828 - 102,082,081 (-)NCBI
Celera595,876,081 - 95,993,467 (-)NCBICelera
Cytogenetic Map5q31NCBI
Frem1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543417,753,925 - 17,901,407 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543417,754,002 - 17,901,416 (-)NCBIChiLan1.0ChiLan1.0
FREM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1915,081,208 - 15,254,581 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl915,081,208 - 15,253,399 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0914,567,781 - 14,748,474 (-)NCBIMhudiblu_PPA_v0panPan3
FREM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11135,174,390 - 35,338,983 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1135,176,934 - 35,310,335 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1133,817,394 - 33,982,281 (-)NCBI
ROS_Cfam_1.01136,078,485 - 36,243,845 (-)NCBI
UMICH_Zoey_3.11134,782,597 - 34,947,751 (-)NCBI
UNSW_CanFamBas_1.01134,574,867 - 34,739,782 (-)NCBI
UU_Cfam_GSD_1.01135,231,916 - 35,396,660 (-)NCBI
Frem1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947149,898,217 - 150,055,395 (-)NCBI
SpeTri2.0NW_0049365398,338,624 - 8,508,031 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FREM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1207,640,839 - 207,801,952 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11207,535,811 - 207,804,525 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21231,366,665 - 231,496,855 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FREM1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11264,681,181 - 64,849,266 (+)NCBI
Frem1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473618,975,104 - 19,346,159 (-)NCBI

Position Markers
BB377904  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38482,898,015 - 82,898,149UniSTSGRCm38
MGSCv37482,543,919 - 82,544,053UniSTSGRCm37
Celera481,433,373 - 81,433,507UniSTS
Cytogenetic Map4C3UniSTS
Whitehead/MRC_RH41158.1UniSTS
D4Mit79  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38482,990,787 - 82,990,923UniSTSGRCm38
MGSCv37482,636,691 - 82,636,827UniSTSGRCm37
Celera481,526,438 - 81,526,572UniSTS
Cytogenetic Map4C3UniSTS
cM Map440.0UniSTS
Whitehead Genetic432.8UniSTS
Whitehead/MRC_RH41158.1UniSTS
Whitehead_YAC4 UniSTS
Frem1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38482,940,318 - 82,940,724UniSTSGRCm38
MGSCv37482,586,222 - 82,586,628UniSTSGRCm37
Celera481,475,672 - 81,476,078UniSTS
Cytogenetic Map4C3UniSTS
cM Map4 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117215009Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261689063979Mouse
1357645Lvrq9_mliver weight QTL 9 (mouse)Not determined41789261689063979Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261689063979Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261689063979Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000129100000Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108500000Mouse
1301941Mmtg1_mmodifier of mammary tumor growth 1 (mouse)Not determined44565844283180920Mouse
1558948Ath8_matherosclerosis 8 (mouse)Not determined445658442105299798Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138615442Mouse
1300966Pabr2_mplasma apolipoprotein B (human) regulator 2 (mouse)Not determined446332646105944663Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123233418Mouse
1301213Lgth3_mbody length 3 (mouse)Not determined45018202584182171Mouse
1301995Lprm1_mlymphoproliferation modifier 1 (mouse)Not determined45018202584182171Mouse
13207572Spir2_mStreptococcus pneumoniae infection resistance 2 (mouse)45068279588592400Mouse
1301033Abbp2_mA/J and C57BL/6 blood pressure 2 (mouse)Not determined45355083993875068Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124161387Mouse
26884434Zlq1_mzygomatic length QTL 1, 5 week (mouse)453700000103400000Mouse
13524838Hbasrq1a_mhabituation of the acoustic startle response QTL 1a (mouse)45455335288553352Mouse
13524841Hbasrq1_mhabituation of the acoustic startle response QTL 1 (mouse)45455335288553352Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000129100000Mouse
27095934Ulnl2_mulna length 2, 5 week (mouse)45770000094900000Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155600000Mouse
10043964Obq26_mobesity QTL 26 (mouse)Not determined45912901493129014Mouse
1301190Cd4ts2_mCD4 T cell subset 2 (mouse)Not determined46022704094227187Mouse
1357507Synch2_msynechia 2 (mouse)Not determined46022704094227187Mouse
1357870Pfat1_mpredicted fat percentage 1 (mouse)Not determined46370128997701448Mouse
12879903Berr8_mberghei resistance locus 8 (mouse)46430422398304223Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465400000119000000Mouse
13506251Cytrq1_mcytokine response QTL 1 (mouse)46579984999799849Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465800000146500000Mouse
27095938Ulnl6_mulna length 6, 10 week (mouse)46680000098700000Mouse
1301757Tlsr4_mthymic lymphoma suppressor region 4 (mouse)Not determined466838893100839021Mouse
1357561Mbsyd_mmetabolic syndrome (mouse)Not determined466970208100970351Mouse
27095900Scvln9_msacral vertebrae length 2, 10 week (mouse)468100000107300000Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468100000130500000Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468100000150800000Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469200000131000000Mouse
1302057Pgia27_mproteoglycan induced arthritis 27 (mouse)Not determined470148990104149227Mouse
1301739Pitm2_mprion incubation time 2 (mouse)Not determined472063832106063979Mouse
1302044Nss1_mNOD Sjogren's syndrome 1 (mouse)Not determined472063832106063979Mouse
12879897Berr4_mberghei resistance locus 4 (mouse)472063832106063979Mouse
1302031Bulb1_mbulb size 1 (mouse)Not determined474145650108145792Mouse
1301597Anxty_manxiety (mouse)Not determined474219337128115487Mouse
10412193Plep_mplasma lepin levels (mouse)Not determined474556462108556746Mouse
11532700Sluc43d_msusceptibility to lung cancer 43d (mouse)474556462108556746Mouse
11532701Sluc43e_msusceptibility to lung cancer 43e (mouse)474556462108556746Mouse
11532702Sluc43f_msusceptibility to lung cancer 43f (mouse)474556462108556746Mouse
11532703Sluc43g_msusceptibility to lung cancer 43g (mouse)474556462108556746Mouse
11532704Sluc43a_msusceptibility to lung cancer 43a (mouse)474556462108556746Mouse
11532705Sluc43b_msusceptibility to lung cancer 43b (mouse)474556462108556746Mouse
11532706Sluc43c_msusceptibility to lung cancer 43c (mouse)474556462108556746Mouse
11532707Sluc43h_msusceptibility to lung cancer 43h (mouse)474556462108556746Mouse
11532708Sluc43i_msusceptibility to lung cancer 43i (mouse)474556462108556746Mouse
26884431Zlq8_mzygomatic length QTL 8, 16 week (mouse)474800000108500000Mouse
26884406Huml3_mhumerus length 3, 10 week (mouse)475700000100300000Mouse
1301545Gauc_mglucose area under curve (mouse)Not determined476874870110875068Mouse
1300697Sle2_msystemic lupus erythmatosus susceptibility 2 (mouse)Not determined478069342112069538Mouse
11039504Ltpr4a_mLeishmania tropica response 4a (mouse)479477514113477630Mouse
11039505Ltpr4c_mLeishmania tropica response 4c (mouse)479477514113477630Mouse
11039506Ltpr4b_mLeishmania tropica response 4b (mouse)479477514113477630Mouse
11039517Ltpr4_mLeishmania tropica response 4 (mouse)479477514113477630Mouse
4142203Lyr_mlymphoma resistance (mouse)Not determined8083420888850951Mouse
12904738Idohtq_miris defect with ocular hypertension QTL (mouse)48083423093224754Mouse
12904933Edlmmq3_mextensor digitorum longus muscle mass QTL 3 (mouse)481325754115325754Mouse
1302204Spm1_msplenomegaly modifier (mouse)Not determined482356158116356345Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2947
Count of miRNA genes:812
Interacting mature miRNAs:1071
Transcripts:ENSMUST00000071708, ENSMUST00000107230, ENSMUST00000127886, ENSMUST00000130889, ENSMUST00000131102, ENSMUST00000133610, ENSMUST00000141841, ENSMUST00000170248
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001198811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_154662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011250055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001784157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003954973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_390326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB160986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ616838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL670958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL773515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000071708   ⟹   ENSMUSP00000071627
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl482,897,927 - 83,021,102 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107230   ⟹   ENSMUSP00000102849
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl482,897,927 - 83,052,339 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127886   ⟹   ENSMUSP00000122467
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl482,938,426 - 82,970,703 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130889
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl482,915,633 - 82,924,792 (-)Ensembl
RefSeq Acc Id: ENSMUST00000131102
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl482,992,935 - 83,052,339 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133610
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl482,900,564 - 82,914,434 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141841
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl482,936,109 - 82,940,882 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170248   ⟹   ENSMUSP00000125809
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl482,897,920 - 83,052,167 (-)Ensembl
RefSeq Acc Id: NM_001198811   ⟹   NP_001185740
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,970,403 (-)NCBI
GRCm38482,897,920 - 83,052,166 (-)NCBI
Celera481,433,278 - 81,588,111 (-)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_177863   ⟹   NP_808531
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,939,339 (-)NCBI
GRCm38482,897,920 - 83,021,102 (-)NCBI
MGSCv37482,543,831 - 82,667,006 (-)RGD
Celera481,433,278 - 81,588,111 (-)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_154662
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,939,339 (-)NCBI
GRCm38482,897,920 - 83,021,102 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006538013   ⟹   XP_006538076
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,970,623 (-)NCBI
GRCm38482,897,920 - 83,052,390 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006538014   ⟹   XP_006538077
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,940,872 (-)NCBI
GRCm38482,897,920 - 83,022,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006538015   ⟹   XP_006538078
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,969,957 (-)NCBI
GRCm38482,897,920 - 83,051,720 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006538018   ⟹   XP_006538081
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,917,123 (-)NCBI
GRCm38482,897,920 - 82,998,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011250055   ⟹   XP_011248357
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,970,623 (-)NCBI
GRCm38482,897,920 - 83,052,390 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253616   ⟹   XP_030109476
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,930,188 (-)NCBI
GRCm38482,897,920 - 83,011,951 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164191   ⟹   XP_036020084
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,884,275 (-)NCBI
RefSeq Acc Id: XM_036164192   ⟹   XP_036020085
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,864,514 (-)NCBI
RefSeq Acc Id: XR_001784157
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,868,493 - 82,970,743 (-)NCBI
GRCm38482,950,256 - 83,052,506 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003954973
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,907,292 - 82,970,743 (-)NCBI
GRCm38482,989,055 - 83,052,506 (-)NCBI
Sequence:
RefSeq Acc Id: XR_390326
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39482,816,157 - 82,970,743 (-)NCBI
GRCm38482,897,920 - 83,052,506 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_808531   ⟸   NM_177863
- Peptide Label: isoform 1 precursor
- UniProtKB: Q684R7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001185740   ⟸   NM_001198811
- Peptide Label: isoform 2 precursor
- UniProtKB: Q684R7 (UniProtKB/Swiss-Prot),   A2ADN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538076   ⟸   XM_006538013
- Peptide Label: isoform X1
- UniProtKB: Q684R7 (UniProtKB/Swiss-Prot),   A2ADN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538078   ⟸   XM_006538015
- Peptide Label: isoform X1
- UniProtKB: Q684R7 (UniProtKB/Swiss-Prot),   A2ADN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538077   ⟸   XM_006538014
- Peptide Label: isoform X1
- UniProtKB: Q684R7 (UniProtKB/Swiss-Prot),   A2ADN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006538081   ⟸   XM_006538018
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011248357   ⟸   XM_011250055
- Peptide Label: isoform X1
- UniProtKB: Q684R7 (UniProtKB/Swiss-Prot),   A2ADN1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030109476   ⟸   XM_030253616
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000125809   ⟸   ENSMUST00000170248
RefSeq Acc Id: ENSMUSP00000071627   ⟸   ENSMUST00000071708
RefSeq Acc Id: ENSMUSP00000122467   ⟸   ENSMUST00000127886
RefSeq Acc Id: ENSMUSP00000102849   ⟸   ENSMUST00000107230
RefSeq Acc Id: XP_036020084   ⟸   XM_036164191
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036020085   ⟸   XM_036164192
- Peptide Label: isoform X4
Protein Domains
C-type lectin   Calx-beta

Promoters
RGD ID:6883736
Promoter ID:EPDNEW_M5319
Type:multiple initiation site
Name:Frem1_1
Description:Mus musculus Fras1 related extracellular matrix protein 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38483,052,166 - 83,052,226EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2670972 AgrOrtholog
Ensembl Genes ENSMUSG00000059049 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000071627 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000102849 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000122467 UniProtKB/TrEMBL
  ENSMUSP00000125809 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000071708 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000107230 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000127886 UniProtKB/TrEMBL
  ENSMUST00000170248 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2030 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CalX-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calx_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CSPG_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FREM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:329872 UniProtKB/Swiss-Prot
MGD MGI:2670972 ENTREZGENE
NCBI Gene 329872 ENTREZGENE
PANTHER PTHR45739:SF7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Calx-beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Frem1 PhenoGen
PROSITE C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CSPG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF141072 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2ADN1 ENTREZGENE, UniProtKB/TrEMBL
  E9Q5Z7_MOUSE UniProtKB/TrEMBL
  F7D5I3_MOUSE UniProtKB/TrEMBL
  FREM1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q5H8C2 UniProtKB/Swiss-Prot
  Q5M7B3 UniProtKB/Swiss-Prot
  Q8C732 UniProtKB/Swiss-Prot