Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | N4bp2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of N4BP2 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of N4BP2 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of N4BP2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of N4BP2 mRNA | CTD | PMID:29097150 | 17beta-estradiol | affects expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Estradiol affects the expression of N4BP2 mRNA | CTD | PMID:32145629 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of N4BP2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of N4BP2 mRNA | CTD | PMID:33387578 | 2-hydroxypropanoic acid | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of N4BP2 mRNA | CTD | PMID:30851411 | 2-palmitoylglycerol | increases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of N4BP2 mRNA | CTD | PMID:37199045 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | N4BP2 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of N4BP2 gene | CTD | PMID:31601247 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of N4BP2 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of N4BP2 mRNA | CTD | PMID:24780913 | aflatoxin B1 | affects expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of N4BP2 protein | CTD | PMID:20106945 | aflatoxin B1 | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of N4BP2 mRNA | CTD | PMID:27153756 | aflatoxin B1 | decreases methylation | ISO | N4BP2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of N4BP2 gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | decreases methylation | ISO | N4BP2 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of N4BP2 intron | CTD | PMID:30157460 | aflatoxin M1 | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of N4BP2 mRNA | CTD | PMID:30928695 | all-trans-retinoic acid | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of N4BP2 mRNA | CTD | PMID:33167477 | aristolochic acid A | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of N4BP2 mRNA | CTD | PMID:33212167 | atrazine | affects methylation | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of N4BP2 gene | CTD | PMID:35440735 | benzo[a]pyrene | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of N4BP2 mRNA | CTD | PMID:20106945 and PMID:32234424 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of N4BP2 exon and Benzo(a)pyrene results in increased methylation of N4BP2 intron | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | N4BP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of N4BP2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of N4BP2 mRNA | CTD | PMID:22228805 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of N4BP2 mRNA | CTD | PMID:26063408 | bisphenol A | affects expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of N4BP2 mRNA | CTD | PMID:32145629 | bisphenol A | increases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of N4BP2 mRNA | CTD | PMID:29097150 | bisphenol A | decreases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of N4BP2 mRNA | CTD | PMID:25181051 | cadmium atom | multiple interactions | ISO | N4BP2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of N4BP2 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | N4BP2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of N4BP2 mRNA | CTD | PMID:35301059 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in increased expression of N4BP2 mRNA | CTD | PMID:25620056 | copper atom | multiple interactions | ISO | N4BP2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of N4BP2 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | N4BP2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of N4BP2 mRNA | CTD | PMID:20971185 | crocidolite asbestos | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in decreased expression of N4BP2 mRNA | CTD | PMID:29523930 | Cuprizon | increases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of N4BP2 mRNA | CTD | PMID:26577399 | cyclosporin A | increases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of N4BP2 mRNA | CTD | PMID:20106945 more ... | doxorubicin | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of N4BP2 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of N4BP2 mRNA | CTD | PMID:29391264 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of N4BP2 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of N4BP2 mRNA | CTD | PMID:23649840 | flutamide | decreases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Flutamide results in decreased expression of N4BP2 mRNA | CTD | PMID:24793618 | formaldehyde | increases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of N4BP2 mRNA | CTD | PMID:23649840 | FR900359 | increases phosphorylation | ISO | N4BP2 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of N4BP2 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | N4BP2 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of N4BP2 gene | CTD | PMID:31601247 | gentamycin | decreases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of N4BP2 mRNA | CTD | PMID:33387578 | methyl methanesulfonate | increases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of N4BP2 mRNA | CTD | PMID:23649840 | microcystin-LR | increases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | cyanoginosin LR results in increased expression of N4BP2 mRNA | CTD | PMID:27796937 | myristicin | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | myristicin results in decreased expression of N4BP2 mRNA | CTD | PMID:24792648 | paracetamol | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of N4BP2 mRNA | CTD | PMID:21420995 | paracetamol | decreases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of N4BP2 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of N4BP2 mRNA | CTD | PMID:27153767 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of N4BP2 mRNA | CTD | PMID:36331819 | rac-lactic acid | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of N4BP2 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | N4BP2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of N4BP2 mRNA | CTD | PMID:23557933 | sodium arsenite | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of N4BP2 mRNA | CTD | PMID:34032870 | succimer | multiple interactions | EXP | | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of N4BP2 mRNA | CTD | PMID:21641980 | sunitinib | increases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of N4BP2 mRNA | CTD | PMID:31533062 | tetrachloromethane | multiple interactions | ISO | N4bp2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of N4BP2 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | N4bp2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of N4BP2 mRNA | CTD | PMID:31150632 | trichostatin A | affects expression | ISO | N4BP2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of N4BP2 mRNA | CTD | PMID:28542535 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of N4BP2 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of N4BP2 mRNA | CTD | PMID:30912803 | tunicamycin | increases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of N4BP2 mRNA | CTD | PMID:22378314 | urethane | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of N4BP2 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of N4BP2 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | N4BP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of N4BP2 mRNA | CTD | PMID:23179753 more ... | |