Evi2a (ecotropic viral integration site 2a) - Rat Genome Database
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Gene: Evi2a (ecotropic viral integration site 2a) Mus musculus
Analyze
Symbol: Evi2a
Name: ecotropic viral integration site 2a
RGD ID: 1616002
MGI Page MGI
Description: Predicted to localize to integral component of membrane. Is expressed in thymus primordium and ureter. Orthologous to human EVI2A (ecotropic viral integration site 2A); INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW491894; ecotropic viral integration site 2A protein; Ev; Evi; Evi-2; EVI-2A; Evi2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391179,417,386 - 79,421,435 (-)NCBIGRCm39mm39
GRCm381179,526,560 - 79,530,609 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1179,526,560 - 79,530,609 (-)EnsemblGRCm38mm10GRCm38
MGSCv371179,340,062 - 79,344,111 (-)NCBIGRCm37mm9NCBIm37
MGSCv361179,342,755 - 79,346,804 (-)NCBImm8
Celera1189,159,242 - 89,163,291 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:1311971   PMID:1346798   PMID:1643308   PMID:1765007   PMID:1969921   PMID:1971252   PMID:2165966   PMID:2167436   PMID:2286379   PMID:2567264   PMID:2851124   PMID:2902634  
PMID:2903254   PMID:7474134   PMID:7514570   PMID:7557989   PMID:7590247   PMID:7601457   PMID:7609078   PMID:7626882   PMID:7751941   PMID:7767000   PMID:7767001   PMID:7769664  
PMID:8026534   PMID:8188678   PMID:8423056   PMID:8563752   PMID:8570653   PMID:8661152   PMID:8672127   PMID:8684458   PMID:8889548   PMID:9098436   PMID:9804998   PMID:10349636  
PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12696059   PMID:15618518   PMID:15905556   PMID:16138909   PMID:16141072   PMID:16141073   PMID:18287559  
PMID:21267068   PMID:21308776  


Genomics

Comparative Map Data
Evi2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391179,417,386 - 79,421,435 (-)NCBIGRCm39mm39
GRCm381179,526,560 - 79,530,609 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1179,526,560 - 79,530,609 (-)EnsemblGRCm38mm10GRCm38
MGSCv371179,340,062 - 79,344,111 (-)NCBIGRCm37mm9NCBIm37
MGSCv361179,342,755 - 79,346,804 (-)NCBImm8
Celera1189,159,242 - 89,163,291 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.81NCBI
EVI2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1731,317,560 - 31,321,884 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1731,316,410 - 31,321,749 (-)EnsemblGRCh38hg38GRCh38
GRCh381731,316,410 - 31,321,622 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371729,643,428 - 29,648,640 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371729,643,428 - 29,648,767 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361726,668,801 - 26,672,843 (-)NCBINCBI36hg18NCBI36
Build 341726,668,801 - 26,672,843NCBI
Celera1726,564,149 - 26,569,490 (-)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1725,854,030 - 25,859,366 (-)NCBIHuRef
CHM1_11729,706,611 - 29,711,950 (-)NCBICHM1_1
Evi2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21064,485,760 - 64,489,660 (-)NCBI
Rnor_6.0 Ensembl1066,870,067 - 66,873,948 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01066,870,048 - 66,873,948 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01064,774,687 - 64,778,587 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41065,713,406 - 65,717,306 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1063,456,573 - 63,460,473 (-)NCBICelera
Cytogenetic Map10q25NCBI
Evi2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554816,346,024 - 6,350,216 (-)NCBIChiLan1.0ChiLan1.0
EVI2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11726,212,899 - 26,216,994 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01725,476,668 - 25,482,394 (+)NCBIMhudiblu_PPA_v0panPan3
EVI2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1941,520,000 - 41,524,103 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Evi2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365383,448,784 - 3,453,369 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EVI2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11243,543,020 - 43,548,586 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21245,370,507 - 45,375,912 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EVI2A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11624,779,056 - 24,784,018 (-)NCBI
Evi2a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248753,899,550 - 3,903,664 (-)NCBI

Position Markers
AW491894  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381179,527,442 - 79,527,571UniSTSGRCm38
MGSCv371179,340,944 - 79,341,073UniSTSGRCm37
Celera1189,160,124 - 89,160,253UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map11B4-5UniSTS
cM Map1146.13UniSTS
Whitehead/MRC_RH111005.69UniSTS
Evi2a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B5UniSTS
cM Map1146.13UniSTS
D11Bhm165  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381179,525,644 - 79,525,912UniSTSGRCm38
MGSCv371179,339,146 - 79,339,414UniSTSGRCm37
Celera1189,158,326 - 89,158,594UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map11B4-5UniSTS
cM Map1146.13UniSTS
cM Map1146.06UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117384671582178599Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
4141365Ltxs3_mlethal factor toxin susceptibility 3 (mouse)Not determined117768304780855532Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:594
Count of miRNA genes:307
Interacting mature miRNAs:354
Transcripts:ENSMUST00000103236, ENSMUST00000133148, ENSMUST00000146611, ENSMUST00000154415, ENSMUST00000170799
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000103236   ⟹   ENSMUSP00000099526
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1179,526,560 - 79,530,588 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133148
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1179,528,068 - 79,530,609 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146611   ⟹   ENSMUSP00000115683
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1179,527,685 - 79,528,146 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154415   ⟹   ENSMUSP00000137045
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1179,526,957 - 79,527,775 (-)Ensembl
RefSeq Acc Id: ENSMUST00000170799   ⟹   ENSMUSP00000125936
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1179,526,568 - 79,530,609 (-)Ensembl
RefSeq Acc Id: NM_001033711   ⟹   NP_001028883
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391179,417,386 - 79,421,435 (-)NCBI
GRCm381179,526,560 - 79,530,609 (-)ENTREZGENE
MGSCv371179,340,062 - 79,344,111 (-)RGD
Celera1189,159,242 - 89,163,291 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010161   ⟹   NP_034291
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391179,417,386 - 79,421,435 (-)NCBI
GRCm381179,526,560 - 79,530,609 (-)ENTREZGENE
MGSCv371179,340,062 - 79,344,111 (-)RGD
Celera1189,159,242 - 89,163,291 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001028883   ⟸   NM_001033711
- Peptide Label: precursor
- UniProtKB: P20934 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_034291   ⟸   NM_010161
- Peptide Label: precursor
- UniProtKB: P20934 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000115683   ⟸   ENSMUST00000146611
RefSeq Acc Id: ENSMUSP00000125936   ⟸   ENSMUST00000170799
RefSeq Acc Id: ENSMUSP00000137045   ⟸   ENSMUST00000154415
RefSeq Acc Id: ENSMUSP00000099526   ⟸   ENSMUST00000103236

Promoters
RGD ID:6820834
Promoter ID:MM_KWN:8759
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Spleen
Transcripts:OTTMUST00000000582,   OTTMUST00000000583
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361179,341,151 - 79,341,952 (-)MPROMDB
RGD ID:6820835
Promoter ID:MM_KWN:8760
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Spleen
Transcripts:NM_001033711,   OTTMUST00000000580,   UC007KKP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361179,343,714 - 79,344,214 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95458 AgrOrtholog
Ensembl Genes ENSMUSG00000078771 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000099526 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000115683 UniProtKB/TrEMBL
  ENSMUSP00000125936 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000137045 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000103236 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000146611 UniProtKB/TrEMBL
  ENSMUST00000154415 UniProtKB/TrEMBL
  ENSMUST00000170799 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Ectropic_vir_integratn_site_2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14017 UniProtKB/Swiss-Prot
MGD MGI:95458 ENTREZGENE
NCBI Gene 14017 ENTREZGENE
PANTHER PTHR15568 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EVI2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Evi2a PhenoGen
PIRSF EVI_S2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt EVI2A_MOUSE UniProtKB/Swiss-Prot
  J3QP09_MOUSE UniProtKB/TrEMBL
  P20934 ENTREZGENE
  Q3TBB7_MOUSE UniProtKB/TrEMBL
  Q5SYH8_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q6DKP1 UniProtKB/Swiss-Prot