Tmed11 (transmembrane p24 trafficking protein 11) - Rat Genome Database

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Gene: Tmed11 (transmembrane p24 trafficking protein 11) Mus musculus
Analyze
Symbol: Tmed11
Name: transmembrane p24 trafficking protein 11
RGD ID: 1615886
MGI Page MGI
Description: Predicted to enable cargo receptor activity. Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human TMED11P (transmembrane p24 trafficking protein 11, pseudogene).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1810008K16Rik; glycoprotein 25L; GP25L; p24 family protein alpha-1; p24alpha1; transmembrane emp24 domain-containing protein 11; transmembrane emp24 protein transport domain containing
RGD Orthologs
Human
Dog
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395108,925,101 - 108,943,229 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5108,925,101 - 108,943,229 (-)EnsemblGRCm39 Ensembl
GRCm385108,777,235 - 108,795,363 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5108,777,235 - 108,795,363 (-)EnsemblGRCm38mm10GRCm38
MGSCv375109,206,254 - 109,224,382 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365109,017,537 - 109,035,665 (-)NCBIMGSCv36mm8
Celera5105,897,920 - 105,916,056 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map553.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11835574   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:18160786   PMID:21677750   PMID:21873635  


Genomics

Comparative Map Data
Tmed11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395108,925,101 - 108,943,229 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5108,925,101 - 108,943,229 (-)EnsemblGRCm39 Ensembl
GRCm385108,777,235 - 108,795,363 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5108,777,235 - 108,795,363 (-)EnsemblGRCm38mm10GRCm38
MGSCv375109,206,254 - 109,224,382 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365109,017,537 - 109,035,665 (-)NCBIMGSCv36mm8
Celera5105,897,920 - 105,916,056 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map553.24NCBI
TMED11P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3841,115,197 - 1,123,164 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl41,115,263 - 1,153,726 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl41,115,197 - 1,136,150 (-)EnsemblGRCh38hg38GRCh38
GRCh3741,108,985 - 1,116,952 (-)NCBIGRCh37GRCh37hg19GRCh37
Celera41,043,419 - 1,051,386 (-)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef41,078,724 - 1,086,691 (-)NCBIHuRef
CHM1_141,108,775 - 1,116,742 (-)NCBICHM1_1
T2T-CHM13v2.041,113,920 - 1,121,887 (-)NCBIT2T-CHM13v2.0
TMED11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1391,435,697 - 91,452,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl391,435,697 - 91,452,352 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha393,901,049 - 93,917,719 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0392,432,373 - 92,449,046 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl392,432,373 - 92,449,046 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1391,605,732 - 91,622,403 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0391,658,813 - 91,675,451 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0392,042,679 - 92,059,350 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Tmed11
463 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:11
Count of miRNA genes:11
Interacting mature miRNAs:11
Transcripts:ENSMUST00000004943
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576190263110190479Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576280786110280917Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576280786110280917Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576280786110280917Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576445064110445225Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576445064110445225Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576445064110445225Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576445064110445225Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579539640113539786Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
10045978Tir10_mtrypanosome infection response 10 (mouse)Not determined598019649114021986Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined598019649116876624Mouse
1301877Bbaa3_mB.burgdorferi-associated arthritis 3 (mouse)Not determined599455285112465722Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5103047866115538059Mouse
25314317Sccor3_msynaptonemal complex length to mean MLH1 count ratio 3 (mouse)5104347866114738061Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
1357886Diht_mdopamine-induced hypothermia (mouse)Not determined5104498738115101540Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
1357901Mdmsc2_mmodifier of muscularity 2 (mouse)Not determined5107561006112434786Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108762509126882944Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000004943   ⟹   ENSMUSP00000004943
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5108,925,101 - 108,943,229 (-)Ensembl
GRCm38.p6 Ensembl5108,777,235 - 108,795,363 (-)Ensembl
RefSeq Acc Id: NM_026109   ⟹   NP_080385
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395108,925,101 - 108,943,229 (-)NCBI
GRCm385108,777,235 - 108,795,363 (-)ENTREZGENE
MGSCv375109,206,254 - 109,224,382 (-)RGD
Celera5105,897,920 - 105,916,056 (-)RGD
cM Map5 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_080385   ⟸   NM_026109
- Peptide Label: precursor
- UniProtKB: Q9D2R4 (UniProtKB/Swiss-Prot),   A2RTW8 (UniProtKB/TrEMBL),   Q9D941 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000004943   ⟸   ENSMUST00000004943
Protein Domains
GOLD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D2R4-F1-model_v2 AlphaFold Q9D2R4 1-215 view protein structure

Promoters
RGD ID:6887488
Promoter ID:EPDNEW_M7195
Type:multiple initiation site
Name:Tmed11_1
Description:Mus musculus transmembrane p24 trafficking protein 11 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385108,795,365 - 108,795,425EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914616 AgrOrtholog
Ensembl Genes ENSMUSG00000004821 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000004943 ENTREZGENE
  ENSMUST00000004943.2 UniProtKB/Swiss-Prot
InterPro GOLD_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TMP21-related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67366 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1914616 ENTREZGENE
NCBI Gene 67366 ENTREZGENE
PANTHER PTHR22811 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22811:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EMP24_GP25L UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tmed11 PhenoGen
PROSITE GOLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EMP24_GP25L UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2RTW8 ENTREZGENE, UniProtKB/TrEMBL
  Q9D2R4 ENTREZGENE
  Q9D941 ENTREZGENE, UniProtKB/TrEMBL
  TMD11_MOUSE UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-04 Tmed11  transmembrane p24 trafficking protein 11    transmembrane emp24 protein transport domain containing  Symbol and/or name change 5135510 APPROVED