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Gene: Mtcl1 (microtubule crosslinking factor 1) Mus musculus
Symbol: Mtcl1
Name: microtubule crosslinking factor 1
Description: Exhibits microtubule binding activity and protein homodimerization activity. Involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; positive regulation of microtubule motor activity; and positive regulation of protein targeting to membrane. Localizes to several cellular components, including the apicolateral plasma membrane; cytoskeleton; and lateral plasma membrane. Is expressed in several structures, including alimentary system; cranial ganglion; limb segment; metanephros; and neural ectoderm. Orthologous to human MTCL1 (microtubule crosslinking factor 1); INTERACTS WITH 1,1-dichloroethene; aldrin; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110012J17Rik; Ccdc165; coiled-coil domain-containing protein 165; D130071O13; hypothetical protein LOC68617; Kiaa0802; MGC77963; microtubule cross-linking factor 1; mKIAA0802; RP23-424B7.1; SOGA family member 2; Soga2; t8219b25
Homo sapiens (human) : MTCL1 (microtubule crosslinking factor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mtcl1 (microtubule crosslinking factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtcl1 (microtubule crosslinking factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MTCL1 (microtubule crosslinking factor 1)
Canis lupus familiaris (dog) : MTCL1 (microtubule crosslinking factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtcl1 (microtubule crosslinking factor 1)
Sus scrofa (pig) : MTCL1 (microtubule crosslinking factor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1766,336,982 - 66,449,750 (-)Ensembl
GRCm381766,336,980 - 66,449,806 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371766,686,322 - 66,799,090 (-)NCBIGRCm37mm9NCBIm37
MGSCv361766,241,933 - 66,290,855 (-)NCBImm8
Celera1770,637,666 - 70,750,457 (-)NCBICelera
Cytogenetic Map17 E1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mtcl1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615879
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.