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Gene: Fbxo31 (F-box protein 31) Mus musculus
Symbol: Fbxo31
Name: F-box protein 31
Description: Predicted to have cyclin binding activity. Predicted to be involved in mitotic G1 DNA damage checkpoint; positive regulation of neurogenesis; and proteasome-mediated ubiquitin-dependent protein catabolic process. Localizes to neuronal cell body. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in several structures, including adrenal gland; brain; early embryo; genitourinary system; and gut gland. Orthologous to human FBXO31 (F-box protein 31); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxynon-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110003O08Rik; 2310046N15Rik; F-box only protein 14; F-box only protein 31; Fbx14; Fbxo14; hypothetical protein LOC76291; RIKEN cDNA 1110003O08 gene; uncharacterized protein LOC76291
Homo sapiens (human) : FBXO31 (F-box protein 31)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxo31 (F-box protein 31)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo31 (F-box protein 31)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO31 (F-box protein 31)
Canis lupus familiaris (dog) : FBXO31 (F-box protein 31)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo31 (F-box protein 31)
Sus scrofa (pig) : FBXO31 (F-box protein 31)
Chlorocebus sabaeus (African green monkey) : FBXO31 (F-box protein 31)
Heterocephalus glaber (naked mole-rat) : Fbxo31 (F-box protein 31)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl8121,549,440 - 121,578,806 (-)EnsemblGRCm38mm10GRCm38
GRCm388121,549,443 - 121,578,864 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378124,075,879 - 124,102,706 (-)NCBIGRCm37mm9NCBIm37
MGSCv368124,437,993 - 124,464,843 (-)NCBImm8
Celera8125,773,510 - 125,800,328 (-)NCBICelera
Cytogenetic Map8E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Fbxo31
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615803
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.