6030468B19Rik (RIKEN cDNA 6030468B19 gene) - Rat Genome Database

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Gene: 6030468B19Rik (RIKEN cDNA 6030468B19 gene) Mus musculus
Analyze
Symbol: 6030468B19Rik
Name: RIKEN cDNA 6030468B19 gene
RGD ID: 1615794
MGI Page MGI
Description: Predicted to enable transmembrane signaling receptor activity. Involved in mature B cell differentiation involved in immune response and positive regulation of immunoglobulin production in mucosal tissue. Predicted to be located in extracellular space. Predicted to be active in external side of plasma membrane. Orthologous to human C17orf99 (chromosome 17 open reading frame 99).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC77727; Il-40; interleukin-40; RP23-151N19.6; uncharacterized protein C17orf99 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911117,688,460 - 117,698,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11117,688,486 - 117,698,127 (+)EnsemblGRCm39 Ensembl
GRCm3811117,797,634 - 117,807,308 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11117,797,660 - 117,807,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711117,658,974 - 117,668,622 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611117,613,750 - 117,623,391 (+)NCBIMGSCv36mm8
Celera11129,541,705 - 129,552,432 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1182.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:20562862   PMID:21677750   PMID:21873635   PMID:28978694  


Genomics

Comparative Map Data
6030468B19Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911117,688,460 - 117,698,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11117,688,486 - 117,698,127 (+)EnsemblGRCm39 Ensembl
GRCm3811117,797,634 - 117,807,308 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11117,797,660 - 117,807,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711117,658,974 - 117,668,622 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611117,613,750 - 117,623,391 (+)NCBIMGSCv36mm8
Celera11129,541,705 - 129,552,432 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1182.96NCBI
C17orf99
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381778,145,571 - 78,166,297 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1778,146,385 - 78,166,297 (+)EnsemblGRCh38hg38GRCh38
GRCh371776,142,466 - 76,162,378 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361776,156,151 - 76,162,364 (+)NCBINCBI36Build 36hg18NCBI36
Celera1772,738,832 - 72,758,765 (+)NCBICelera
Cytogenetic Map17q25.3NCBI
HuRef1771,566,709 - 71,586,521 (+)NCBIHuRef
CHM1_11776,206,987 - 76,226,902 (+)NCBICHM1_1
T2T-CHM13v2.01779,039,349 - 79,060,396 (+)NCBIT2T-CHM13v2.0
C10h17orf99
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810103,514,067 - 103,526,132 (+)NCBIGRCr8
mRatBN7.210103,015,371 - 103,027,407 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10103,016,505 - 103,027,407 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.010106,800,040 - 106,810,153 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10106,800,142 - 106,809,239 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010106,441,143 - 106,449,835 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10101,576,765 - 101,587,314 (+)NCBICelera
Cytogenetic Map10q32.2NCBI
CUNH17orf99
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555064,397,221 - 4,408,645 (-)NCBIChiLan1.0ChiLan1.0
C19H17orf99
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21994,211,470 - 94,219,179 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11799,039,113 - 99,044,015 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01772,223,073 - 72,244,049 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11777,776,151 - 77,796,139 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1777,776,151 - 77,796,139 (+)Ensemblpanpan1.1panPan2
C9H17orf99
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.192,977,401 - 2,987,450 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl92,976,893 - 2,987,564 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha93,660,848 - 3,670,792 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.093,655,241 - 3,665,198 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl93,655,760 - 3,665,205 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.193,678,251 - 3,688,175 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.093,802,459 - 3,812,417 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.093,883,872 - 3,893,869 (-)NCBIUU_Cfam_GSD_1.0
CUNH17orf99
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11670,172,850 - 70,178,358 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607741,281,810 - 41,287,209 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH17orf99
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248017,668,551 - 7,678,531 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in 6030468B19Rik
298 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:165
Count of miRNA genes:159
Interacting mature miRNAs:165
Transcripts:ENSMUST00000106331
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100254186120887165Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000106331   ⟹   ENSMUSP00000101938
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11117,688,486 - 117,698,127 (+)Ensembl
GRCm38.p6 Ensembl11117,797,660 - 117,807,301 (+)Ensembl
RefSeq Acc Id: NM_029964   ⟹   NP_084240
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911117,688,486 - 117,698,134 (+)NCBI
GRCm3811117,797,660 - 117,807,308 (+)NCBI
MGSCv3711117,658,974 - 117,668,622 (+)RGD
Celera11129,541,705 - 129,552,432 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534498   ⟹   XP_006534561
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911117,688,471 - 117,698,094 (+)NCBI
GRCm3811117,797,645 - 117,807,268 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006534499   ⟹   XP_006534562
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911117,688,476 - 117,698,131 (+)NCBI
GRCm3811117,797,649 - 117,807,305 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006534500   ⟹   XP_006534563
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911117,688,460 - 117,698,094 (+)NCBI
GRCm3811117,797,634 - 117,807,268 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_084240 (Get FASTA)   NCBI Sequence Viewer  
  XP_006534561 (Get FASTA)   NCBI Sequence Viewer  
  XP_006534562 (Get FASTA)   NCBI Sequence Viewer  
  XP_006534563 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB31985 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000101938
  ENSMUSP00000101938.2
GenBank Protein Q9CX63 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_084240   ⟸   NM_029964
- Peptide Label: precursor
- UniProtKB: B1ATC1 (UniProtKB/Swiss-Prot),   Q9CX63 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534563   ⟸   XM_006534500
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006534561   ⟸   XM_006534498
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006534562   ⟸   XM_006534499
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000101938   ⟸   ENSMUST00000106331

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CX63-F1-model_v2 AlphaFold Q9CX63 1-252 view protein structure

Promoters
RGD ID:8677528
Promoter ID:EPDNEW_M16795
Type:multiple initiation site
Name:6030468B19Rik_1
Description:Mus musculus RIKEN cDNA 6030468B19 gene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811117,797,741 - 117,797,801EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1924977 AgrOrtholog
Ensembl Genes ENSMUSG00000025573 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000106331 ENTREZGENE
  ENSMUST00000106331.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_C17orf99 UniProtKB/Swiss-Prot
KEGG Report mmu:77727 UniProtKB/Swiss-Prot
MGD MGI:1924977 ENTREZGENE
NCBI Gene 77727 ENTREZGENE
Pfam Ig_C17orf99 UniProtKB/Swiss-Prot
PhenoGen 6030468B19Rik PhenoGen
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt B1ATC1 ENTREZGENE
  IL40_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B1ATC1 UniProtKB/Swiss-Prot