Arfip1 (ADP-ribosylation factor interacting protein 1) - Rat Genome Database

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Gene: Arfip1 (ADP-ribosylation factor interacting protein 1) Mus musculus
Analyze
Symbol: Arfip1
Name: ADP-ribosylation factor interacting protein 1
RGD ID: 1615779
MGI Page MGI
Description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Predicted to be involved in intracellular protein transport; negative regulation of retrograde transport, endosome to Golgi; and regulation of Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within regulation of protein secretion. Predicted to be located in Golgi membrane and cytosol. Predicted to be active in trans-Golgi network membrane. Orthologous to human ARFIP1 (ADP ribosylation factor interacting protein 1); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; cyclosporin A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310030I10Rik; Ar; Arfaptin; arfaptin-1; AW123087; D3Ertd598; D3Ertd598e
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm8468  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39384,403,400 - 84,490,075 (-)NCBIGRCm39mm39
GRCm39 Ensembl384,403,733 - 85,794,825 (-)Ensembl
GRCm39 Ensembl384,403,400 - 84,489,932 (-)Ensembl
GRCm38384,496,093 - 84,582,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl384,496,426 - 85,887,518 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl384,496,093 - 84,582,625 (-)EnsemblGRCm38mm10GRCm38
MGSCv37384,299,985 - 84,390,065 (-)NCBIGRCm37mm9NCBIm37
MGSCv36384,581,990 - 84,672,070 (-)NCBImm8
Celera384,506,047 - 84,596,205 (-)NCBICelera
Cytogenetic Map3F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:11591653   PMID:12466851   PMID:12477932   PMID:12520002  
PMID:14610273   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21677750   PMID:21873635   PMID:29459677  


Genomics

Comparative Map Data
Arfip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39384,403,400 - 84,490,075 (-)NCBIGRCm39mm39
GRCm39 Ensembl384,403,733 - 85,794,825 (-)Ensembl
GRCm39 Ensembl384,403,400 - 84,489,932 (-)Ensembl
GRCm38384,496,093 - 84,582,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl384,496,426 - 85,887,518 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl384,496,093 - 84,582,625 (-)EnsemblGRCm38mm10GRCm38
MGSCv37384,299,985 - 84,390,065 (-)NCBIGRCm37mm9NCBIm37
MGSCv36384,581,990 - 84,672,070 (-)NCBImm8
Celera384,506,047 - 84,596,205 (-)NCBICelera
Cytogenetic Map3F1NCBI
ARFIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4152,779,937 - 152,918,463 (+)EnsemblGRCh38hg38GRCh38
GRCh384152,779,954 - 152,912,357 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374153,701,106 - 153,833,509 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364153,920,562 - 154,052,514 (+)NCBINCBI36hg18NCBI36
Build 344154,058,727 - 154,189,053NCBI
Celera4151,025,104 - 151,157,752 (+)NCBI
Cytogenetic Map4q31.3NCBI
HuRef4149,427,137 - 149,559,291 (+)NCBIHuRef
CHM1_14153,679,080 - 153,811,057 (+)NCBICHM1_1
Arfip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22169,843,804 - 169,924,136 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2169,843,801 - 169,923,142 (-)Ensembl
Rnor_6.02183,503,250 - 183,582,798 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2183,504,330 - 183,582,553 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02202,911,579 - 202,991,075 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42176,275,425 - 176,353,675 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12176,225,530 - 176,303,781 (-)NCBI
Celera2163,843,358 - 163,921,484 (-)NCBICelera
Cytogenetic Map2q34NCBI
Arfip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554717,238,456 - 7,351,055 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554717,238,456 - 7,349,767 (+)NCBIChiLan1.0ChiLan1.0
ARFIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14156,770,384 - 156,901,754 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4156,770,510 - 156,901,754 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04145,119,881 - 145,252,601 (+)NCBIMhudiblu_PPA_v0panPan3
ARFIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11550,618,392 - 50,756,300 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1550,618,087 - 50,755,339 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1550,965,110 - 51,103,001 (+)NCBI
ROS_Cfam_1.01551,305,012 - 51,443,008 (+)NCBI
UMICH_Zoey_3.11550,567,205 - 50,699,297 (+)NCBI
UNSW_CanFamBas_1.01550,666,679 - 50,804,559 (+)NCBI
UU_Cfam_GSD_1.01550,977,655 - 51,115,571 (+)NCBI
Arfip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530139,750,432 - 39,859,883 (-)NCBI
SpeTri2.0NW_0049366892,671,204 - 2,781,107 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARFIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl876,168,388 - 76,270,787 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1876,168,731 - 76,270,554 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2880,737,499 - 80,791,563 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARFIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1799,341,992 - 99,467,715 (+)NCBI
ChlSab1.1 Ensembl799,341,905 - 99,468,909 (+)Ensembl
Vero_WHO_p1.0NW_02366603778,991,937 - 79,118,394 (+)NCBI
Arfip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248584,193,418 - 4,299,445 (+)NCBI

Position Markers
RH131685  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38384,496,095 - 84,496,263UniSTSGRCm38
MGSCv37384,300,017 - 84,300,185UniSTSGRCm37
Celera384,506,079 - 84,506,247UniSTS
Cytogenetic Map3F1UniSTS
AW123087  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38384,496,484 - 84,496,579UniSTSGRCm38
MGSCv37384,300,406 - 84,300,501UniSTSGRCm37
Celera384,506,468 - 84,506,563UniSTS
Cytogenetic Map3F1UniSTS
Whitehead/MRC_RH3857.48UniSTS
UniSTS:234716  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38384,496,562 - 84,496,712UniSTSGRCm38
MGSCv37384,300,484 - 84,300,634UniSTSGRCm37
Celera384,506,546 - 84,506,696UniSTS
Cytogenetic Map3F1UniSTS
D3Ertd598e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38384,496,156 - 84,496,404UniSTSGRCm38
MGSCv37384,300,078 - 84,300,326UniSTSGRCm37
Celera384,506,140 - 84,506,388UniSTS
Cytogenetic Map3F1UniSTS
cM Map3 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33200000142700000Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7521114102782718Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316000000109800000Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316450000130370000Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328900000119100000Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330013439147599053Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337120713143647422Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)341000000116000000Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)344000000101700000Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)352000000102400000Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352300000137500000Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35271817686718412Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35271817686718412Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35271817686718412Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35301585087015850Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356796681100556821Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35900000093000000Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36183275495832934Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366139351100139488Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)368000000128600000Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369661247103661247Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369718176100747974Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370301597104301735Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372232660106232787Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372232660106232787Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375555995109556242Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379641414113641521Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381177336115177481Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382239727116239868Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383556675117556821Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383556675117556821Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383556675117556821Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383556675117556821Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383556675117556821Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383556675117556821Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383556675117556821Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383975596117975728Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1046
Count of miRNA genes:481
Interacting mature miRNAs:545
Transcripts:ENSMUST00000098990, ENSMUST00000107687, ENSMUST00000143514, ENSMUST00000146862, ENSMUST00000154148
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000098990   ⟹   ENSMUSP00000096588
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl384,403,400 - 84,489,841 (-)Ensembl
GRCm38.p6 Ensembl384,496,093 - 84,582,534 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107687   ⟹   ENSMUSP00000103315
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl384,404,511 - 84,489,792 (-)Ensembl
GRCm38.p6 Ensembl384,497,204 - 84,582,485 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125216
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl385,708,354 - 85,794,825 (-)Ensembl
GRCm38.p6 Ensembl385,801,047 - 85,887,518 (-)Ensembl
RefSeq Acc Id: ENSMUST00000143514   ⟹   ENSMUSP00000122964
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl384,405,043 - 84,489,932 (-)Ensembl
GRCm38.p6 Ensembl384,497,736 - 84,582,625 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146862
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl385,724,430 - 85,794,675 (-)Ensembl
GRCm38.p6 Ensembl385,817,123 - 85,887,368 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154148   ⟹   ENSMUSP00000116393
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl384,403,733 - 85,794,823 (-)Ensembl
GRCm38.p6 Ensembl384,496,426 - 85,887,516 (-)Ensembl
RefSeq Acc Id: NM_001081093   ⟹   NP_001074562
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39384,403,400 - 84,489,932 (-)NCBI
GRCm38384,496,093 - 84,582,625 (-)NCBI
MGSCv37384,299,985 - 84,390,065 (-)RGD
Celera384,506,077 - 84,592,662 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001293801   ⟹   NP_001280730
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39384,403,400 - 84,489,932 (-)NCBI
GRCm38384,496,093 - 84,582,625 (-)NCBI
Celera384,506,077 - 84,592,662 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006502482   ⟹   XP_006502545
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39384,403,400 - 84,489,459 (-)NCBI
GRCm38384,496,093 - 84,582,152 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006502484   ⟹   XP_006502547
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39384,403,400 - 84,490,075 (-)NCBI
GRCm38384,496,093 - 84,582,751 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036163483   ⟹   XP_036019376
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39384,403,400 - 84,489,807 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001074562   ⟸   NM_001081093
- Peptide Label: isoform 1
- UniProtKB: G5E8V9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502547   ⟸   XM_006502484
- Peptide Label: isoform X3
- UniProtKB: E9QAY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006502545   ⟸   XM_006502482
- Peptide Label: isoform X1
- UniProtKB: G5E8V9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001280730   ⟸   NM_001293801
- Peptide Label: isoform 2
- UniProtKB: A2RSX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000122964   ⟸   ENSMUST00000143514
RefSeq Acc Id: ENSMUSP00000096588   ⟸   ENSMUST00000098990
RefSeq Acc Id: ENSMUSP00000103315   ⟸   ENSMUST00000107687
RefSeq Acc Id: ENSMUSP00000116393   ⟸   ENSMUST00000154148
RefSeq Acc Id: XP_036019376   ⟸   XM_036163483
- Peptide Label: isoform X2
Protein Domains
AH

Promoters
RGD ID:6833441
Promoter ID:MM_KWN:34724
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   MEF_B4
Transcripts:ENSMUST00000098990,   ENSMUST00000107687,   OTTMUST00000081449
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36384,386,219 - 84,386,719 (-)MPROMDB
RGD ID:6881014
Promoter ID:EPDNEW_M3949
Type:initiation region
Name:Arfip1_1
Description:Mus musculus ADP-ribosylation factor interacting protein 1 ,transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3953  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38384,582,667 - 84,582,727EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1277120 AgrOrtholog
Ensembl Genes ENSMUSG00000074513 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSG00000102805 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000096588 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000103315 UniProtKB/TrEMBL
  ENSMUSP00000116393 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000122964 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000098990 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000107687 UniProtKB/TrEMBL
  ENSMUST00000143514 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000154148 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
InterPro AH/BAR-dom UniProtKB/TrEMBL
  Arfaptin-1 UniProtKB/TrEMBL
  Arfaptin_fam UniProtKB/TrEMBL
  Arfaptin_homology_dom UniProtKB/TrEMBL
KEGG Report mmu:99889 UniProtKB/TrEMBL
MGD MGI:1277120 ENTREZGENE
NCBI Gene 99889 ENTREZGENE
PANTHER PTHR12141 UniProtKB/TrEMBL
  PTHR12141:SF4 UniProtKB/TrEMBL
Pfam Arfaptin UniProtKB/TrEMBL
PhenoGen Arfip1 PhenoGen
PROSITE PS50870 UniProtKB/TrEMBL
SMART Arfaptin UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
UniProt A2RSX9 ENTREZGENE, UniProtKB/TrEMBL
  E9Q3G5_MOUSE UniProtKB/TrEMBL
  E9QAY5 ENTREZGENE, UniProtKB/TrEMBL
  G5E8V9 ENTREZGENE, UniProtKB/TrEMBL