Klrb1f (killer cell lectin-like receptor subfamily B member 1F) - Rat Genome Database

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Gene: Klrb1f (killer cell lectin-like receptor subfamily B member 1F) Mus musculus
Analyze
No known orthologs.
Symbol: Klrb1f
Name: killer cell lectin-like receptor subfamily B member 1F
RGD ID: 1615682
MGI Page MGI
Description: Enables signaling receptor activity. Predicted to be involved in regulation of natural killer cell mediated cytotoxicity. Located in cell surface and plasma membrane. Orthologous to human KLRB1 (killer cell lectin like receptor B1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A630024B12Rik; CD161 antigen-like family member F; MGC130065; MGC130066; natural killer cell surface protein NKR-P1F; Nkr; Nkr-p1f; Nkrp1-f; Nkrp1f; RIKEN cDNA A630024B12 gene
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396129,022,800 - 129,036,687 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6129,022,864 - 129,034,427 (+)EnsemblGRCm39 Ensembl
GRCm386129,045,837 - 129,059,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6129,045,901 - 129,057,464 (+)EnsemblGRCm38mm10GRCm38
MGSCv376128,995,919 - 129,007,489 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366129,011,520 - 129,022,800 (+)NCBIMGSCv36mm8
Celera6130,753,496 - 130,765,104 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (IBA,IDA)
plasma membrane  (IBA,IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11685472   PMID:12466851   PMID:12477932   PMID:12858173   PMID:15489334   PMID:15963483   PMID:16141072   PMID:16141073  
PMID:16143319   PMID:16751398   PMID:19535641   PMID:21267068   PMID:21409442   PMID:21667046   PMID:21677750   PMID:21873635   PMID:23071282   PMID:28340350   PMID:30995786  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:268
Count of miRNA genes:235
Interacting mature miRNAs:243
Transcripts:ENSMUST00000032257
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128180868149588044Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128601582149588044Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4141611Btts_mbitterness tasting (mouse)Not determined6125333609134096586Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
4141151Ath38_matherosclerosis 38 (mouse)Not determined128495857136293176Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128601582149588044Mouse
10412215Cmv3_mcytomegalovirus resistance 3 (mouse)Not determined6128811857137416927Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128601582149588044Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
10412134Cmv4_mcytomegalovirus resistance 4 (mouse)Not determined6127815180136022150Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse

Markers in Region
BB178967  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386129,046,867 - 129,046,992UniSTSGRCm38
MGSCv376128,996,885 - 128,997,010UniSTSGRCm37
Celera6130,754,462 - 130,754,587UniSTS
Cytogenetic Map6F3UniSTS
Whitehead/MRC_RH61296.95UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_153094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_024262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_024263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006506036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017321558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC174446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH011222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY029597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ143105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ237931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ713435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX026279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX443623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX443624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX443625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000032257   ⟹   ENSMUSP00000032257
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6129,022,864 - 129,034,427 (+)Ensembl
GRCm38.p6 Ensembl6129,045,901 - 129,057,464 (+)Ensembl
Ensembl Acc Id: ENSMUST00000203059   ⟹   ENSMUSP00000145316
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6129,022,864 - 129,034,427 (+)Ensembl
GRCm38.p6 Ensembl6129,045,901 - 129,057,464 (+)Ensembl
Ensembl Acc Id: ENSMUST00000204320   ⟹   ENSMUSP00000144813
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6129,022,890 - 129,030,823 (+)Ensembl
GRCm38.p6 Ensembl6129,045,927 - 129,053,860 (+)Ensembl
Ensembl Acc Id: ENSMUST00000204413
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6129,022,888 - 129,029,750 (+)Ensembl
GRCm38.p6 Ensembl6129,045,925 - 129,052,787 (+)Ensembl
Ensembl Acc Id: ENSMUST00000204508   ⟹   ENSMUSP00000145033
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6129,022,883 - 129,033,672 (+)Ensembl
GRCm38.p6 Ensembl6129,045,920 - 129,056,709 (+)Ensembl
Ensembl Acc Id: ENSMUST00000204784
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6129,026,297 - 129,030,829 (+)Ensembl
GRCm38.p6 Ensembl6129,049,334 - 129,053,866 (+)Ensembl
RefSeq Acc Id: NM_153094   ⟹   NP_694734
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396129,022,864 - 129,034,434 (+)NCBI
GRCm386129,045,901 - 129,057,471 (+)NCBI
MGSCv376128,995,919 - 129,007,489 (+)RGD
Celera6130,753,496 - 130,765,104 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_024262
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396129,022,864 - 129,034,434 (+)NCBI
GRCm386129,045,901 - 129,057,471 (+)NCBI
MGSCv376128,995,919 - 129,007,489 (+)RGD
Celera6130,753,496 - 130,765,104 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_024263
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396129,022,864 - 129,034,434 (+)NCBI
GRCm386129,045,901 - 129,057,471 (+)NCBI
MGSCv376128,995,919 - 129,007,489 (+)RGD
Celera6130,753,496 - 130,765,104 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006506036   ⟹   XP_006506099
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396129,026,166 - 129,036,687 (+)NCBI
GRCm386129,049,203 - 129,059,724 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321558   ⟹   XP_017177047
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396129,022,800 - 129,036,687 (+)NCBI
GRCm386129,045,837 - 129,059,724 (+)NCBI
Sequence:
RefSeq Acc Id: NP_694734   ⟸   NM_153094
- UniProtKB: Q8VD98 (UniProtKB/Swiss-Prot),   Q8C9Q1 (UniProtKB/Swiss-Prot),   Q3TDT3 (UniProtKB/Swiss-Prot),   Q1AFZ8 (UniProtKB/Swiss-Prot),   I3QI43 (UniProtKB/TrEMBL),   G4WMX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006506099   ⟸   XM_006506036
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017177047   ⟸   XM_017321558
- Peptide Label: isoform X1
- UniProtKB: G4WMX8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000144813   ⟸   ENSMUST00000204320
Ensembl Acc Id: ENSMUSP00000032257   ⟸   ENSMUST00000032257
Ensembl Acc Id: ENSMUSP00000145316   ⟸   ENSMUST00000203059
Ensembl Acc Id: ENSMUSP00000145033   ⟸   ENSMUST00000204508
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VD98-F1-model_v2 AlphaFold Q8VD98 1-217 view protein structure

Promoters
RGD ID:6891178
Promoter ID:EPDNEW_M9040
Type:initiation region
Name:Klrb1f_1
Description:Mus musculus killer cell lectin-like receptor subfamily B member1F , transcript variant 3, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386129,045,925 - 129,045,985EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2442965 AgrOrtholog
Ensembl Genes ENSMUSG00000030154 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032257 ENTREZGENE
  ENSMUST00000032257.10 UniProtKB/Swiss-Prot
  ENSMUST00000203059 ENTREZGENE
  ENSMUST00000203059.3 UniProtKB/TrEMBL
  ENSMUST00000204320.2 UniProtKB/TrEMBL
  ENSMUST00000204508.3 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KLR_subfamily_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NKR-like_CTLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:232408 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2442965 ENTREZGENE
NCBI Gene Klrb1f ENTREZGENE
PANTHER KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Klrb1f PhenoGen
PROSITE C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUT2_MOUSE UniProtKB/TrEMBL
  A0A0N4SVB7_MOUSE UniProtKB/TrEMBL
  A0A0N4SVZ9_MOUSE UniProtKB/TrEMBL
  G4WMX8 ENTREZGENE, UniProtKB/TrEMBL
  I3QI43 ENTREZGENE, UniProtKB/TrEMBL
  KLRBF_MOUSE UniProtKB/Swiss-Prot
  Q1AFZ8 ENTREZGENE
  Q3KNP3_MOUSE UniProtKB/TrEMBL
  Q3TDT3 ENTREZGENE
  Q8C9Q1 ENTREZGENE
  Q8VD98 ENTREZGENE
UniProt Secondary Q1AFZ8 UniProtKB/Swiss-Prot
  Q3TDT3 UniProtKB/Swiss-Prot
  Q8C9Q1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Klrb1f  killer cell lectin-like receptor subfamily B member 1F  A630024B12Rik  RIKEN cDNA A630024B12 gene  Symbol and/or name change 5135510 APPROVED
2024-08-21 A630024B12Rik  RIKEN cDNA A630024B12 gene  Klrb1f  killer cell lectin-like receptor subfamily B member 1F  Symbol and/or name change 5135510 APPROVED