Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Lemd3 (LEM domain containing 3) Mus musculus
Symbol: Lemd3
Name: LEM domain containing 3
RGD ID: 1615524
Description: Predicted to have chromatin DNA binding activity. Involved in several processes, including blood vessel endothelial cell migration involved in intussusceptive angiogenesis; regulation of extracellular matrix organization; and skeletal muscle cell differentiation. Localizes to nuclear envelope. Is expressed in several structures, including allantois; foregut diverticulum endoderm; lateral plate mesoderm; neural plate; and primitive streak. Human ortholog(s) of this gene implicated in Buschke-Ollendorff syndrome. Orthologous to human LEMD3 (LEM domain containing 3); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI316861; inner nuclear membrane protein Man1; integral inner nuclear membrane protein MAN1; LEM domain-containing protein 3; Ma; Man1
Homo sapiens (human) : LEMD3 (LEM domain containing 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lemd3 (LEM domain containing 3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LEMD3 (LEM domain containing 3)
Canis lupus familiaris (dog) : LEMD3 (LEM domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lemd3 (LEM domain containing 3)
Sus scrofa (pig) : LEMD3 (LEM domain containing 3)
Chlorocebus sabaeus (African green monkey) : LEMD3 (LEM domain containing 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3910120,759,316 - 120,815,491 (-)NCBI
GRCm3810120,923,411 - 120,979,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10120,923,413 - 120,979,332 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710120,360,467 - 120,416,386 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610120,326,471 - 120,382,392 (-)NCBImm8
Celera10123,286,658 - 123,342,549 (-)NCBICelera
Cytogenetic Map10D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lemd3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615524
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.