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Gene: Lama3 (laminin, alpha 3) Mus musculus
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Symbol: Lama3
Name: laminin, alpha 3
Description: Predicted to have integrin binding activity. Predicted to be involved in several processes, including hemidesmosome assembly; integrin-mediated signaling pathway; and morphogenesis of a polarized epithelium. Localizes to the laminin-5 complex. Used to study junctional epidermolysis bullosa and junctional epidermolysis bullosa non-Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Orthologous to human LAMA3 (laminin subunit alpha 3); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [a]3B; epiligrin subunit alpha; kalinin subunit alpha; Lama3B; laminin subunit alpha-3; laminin-5 subunit alpha; laminin-6 subunit alpha; laminin-7 subunit alpha; nicein subunit alpha; nicein, 150kDa
Orthologs:
Homo sapiens (human) : LAMA3 (laminin subunit alpha 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lama3 (laminin subunit alpha 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lama3 (laminin subunit alpha 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100977893 (laminin subunit alpha-3)
Canis lupus familiaris (dog) : LAMA3 (laminin subunit alpha 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lama3 (laminin subunit alpha 3)
Sus scrofa (pig) : LAMA3 (laminin subunit alpha 3)
Chlorocebus sabaeus (green monkey) : LAMA3 (laminin subunit alpha 3)
Heterocephalus glaber (naked mole-rat) : Lama3 (laminin subunit alpha 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1812,333,819 - 12,583,013 (+)Ensembl
GRCm381812,333,417 - 12,583,013 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371812,492,533 - 12,741,522 (+)NCBIGRCm37mm9NCBIm37
MGSCv361812,477,560 - 12,726,182 (+)NCBImm8
Celera1812,567,449 - 12,814,993 (+)NCBICelera
Cytogenetic Map18 A1NCBI
cM Map186.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lama3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615178
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.