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Gene: Lama3 (laminin, alpha 3) Mus musculus
Symbol: Lama3
Name: laminin, alpha 3
Description: Predicted to have integrin binding activity. Predicted to be involved in several processes, including hemidesmosome assembly; integrin-mediated signaling pathway; and morphogenesis of a polarized epithelium. Localizes to the laminin-5 complex. Used to study junctional epidermolysis bullosa and junctional epidermolysis bullosa non-Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Orthologous to human LAMA3 (laminin subunit alpha 3); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [a]3B; epiligrin subunit alpha; kalinin subunit alpha; Lama3B; laminin subunit alpha-3; laminin-5 subunit alpha; laminin-6 subunit alpha; laminin-7 subunit alpha; nicein subunit alpha; nicein, 150kDa
Homo sapiens (human) : LAMA3 (laminin subunit alpha 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lama3 (laminin subunit alpha 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lama3 (laminin subunit alpha 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100977893 (laminin subunit alpha-3)
Canis lupus familiaris (dog) : LAMA3 (laminin subunit alpha 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lama3 (laminin subunit alpha 3)
Sus scrofa (pig) : LAMA3 (laminin subunit alpha 3)
Chlorocebus sabaeus (green monkey) : LAMA3 (laminin subunit alpha 3)
Heterocephalus glaber (naked mole-rat) : Lama3 (laminin subunit alpha 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1812,333,819 - 12,583,013 (+)Ensembl
GRCm381812,333,417 - 12,583,013 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371812,492,533 - 12,741,522 (+)NCBIGRCm37mm9NCBIm37
MGSCv361812,477,560 - 12,726,182 (+)NCBImm8
Celera1812,567,449 - 12,814,993 (+)NCBICelera
Cytogenetic Map18 A1NCBI
cM Map186.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lama3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615178
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.