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Gene: Sox1 (SRY (sex determining region Y)-box 1) Mus musculus
Symbol: Sox1
Name: SRY (sex determining region Y)-box 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including cellular response to leukemia inhibitory factor; generation of neurons; and lens morphogenesis in camera-type eye. Localizes to the nucleus. Is expressed in several structures, including central nervous system; eye; genitourinary system; large intestine; and neural ectoderm. Orthologous to human SOX1 (SRY-box transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BB176347; expressed sequence BB176347; Sox-1; SRY-box containing gene 1; transcription factor SOX-1
Homo sapiens (human) : SOX1 (SRY-box transcription factor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sox1 (SRY-box transcription factor 1)
Canis lupus familiaris (dog) : SOX1 (SRY-box transcription factor 1)
Sus scrofa (pig) : SOX1 (SRY-box transcription factor 1)
Chlorocebus sabaeus (African green monkey) : SOX1 (SRY-box transcription factor 1)
Heterocephalus glaber (naked mole-rat) : Sox1 (SRY-box transcription factor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl812,395,295 - 12,400,126 (+)EnsemblGRCm38mm10GRCm38
GRCm38812,395,519 - 12,399,555 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37812,395,519 - 12,399,555 (+)NCBIGRCm37mm9NCBIm37
MGSCv36812,396,333 - 12,397,508 (+)NCBImm8
Celera812,563,221 - 12,567,238 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Sox1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615160
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.