Cilp2 (cartilage intermediate layer protein 2) - Rat Genome Database
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Gene: Cilp2 (cartilage intermediate layer protein 2) Mus musculus
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Symbol: Cilp2
Name: cartilage intermediate layer protein 2
RGD ID: 1615103
MGI Page MGI
Description: Predicted to have carbohydrate binding activity. Predicted to localize to extracellular region. Orthologous to human CILP2 (cartilage intermediate layer protein 2); INTERACTS WITH 1,2-dimethylhydrazine; benzo[a]pyrene; bisphenol F.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110031K21Rik; AA407300; CLI; CLIP-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,333,016 - 70,340,042 (-)NCBIGRCm39mm39
GRCm38869,880,366 - 69,887,392 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,880,369 - 69,887,687 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,404,265 - 72,411,291 (-)NCBIGRCm37mm9NCBIm37
MGSCv36872,809,357 - 72,816,381 (-)NCBImm8
Celera872,439,082 - 72,446,108 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:20637190   PMID:21677750  
PMID:21880736  


Genomics

Comparative Map Data
Cilp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,333,016 - 70,340,042 (-)NCBIGRCm39mm39
GRCm38869,880,366 - 69,887,392 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,880,369 - 69,887,687 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,404,265 - 72,411,291 (-)NCBIGRCm37mm9NCBIm37
MGSCv36872,809,357 - 72,816,381 (-)NCBImm8
Celera872,439,082 - 72,446,108 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
CILP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1919,538,248 - 19,546,659 (+)EnsemblGRCh38hg38GRCh38
GRCh381919,538,265 - 19,546,659 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371919,649,057 - 19,657,468 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361919,510,074 - 19,518,468 (+)NCBINCBI36hg18NCBI36
Build 341919,510,114 - 19,517,903NCBI
Celera1919,553,136 - 19,561,530 (+)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1919,211,294 - 19,219,688 (+)NCBIHuRef
CHM1_11919,649,978 - 19,658,372 (+)NCBICHM1_1
Cilp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01621,288,782 - 21,295,869 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,288,876 - 21,295,869 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01621,204,607 - 21,211,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41620,024,989 - 20,031,984 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11620,024,986 - 20,031,468 (+)NCBI
Celera1619,729,307 - 19,736,298 (+)NCBICelera
Cytogenetic Map16p14NCBI
Cilp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,414,495 - 2,421,380 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,414,502 - 2,421,166 (-)NCBIChiLan1.0ChiLan1.0
CILP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11919,973,871 - 19,982,293 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,973,871 - 19,982,293 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01918,976,189 - 18,985,143 (+)NCBIMhudiblu_PPA_v0panPan3
CILP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2043,703,274 - 43,722,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12043,703,467 - 43,712,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Cilp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365961,928,733 - 1,936,606 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CILP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,383,570 - 58,391,977 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,383,568 - 58,391,973 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,306,042 - 58,314,435 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CILP2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl618,001,197 - 18,009,122 (+)Ensembl
ChlSab1.1618,001,103 - 18,009,776 (+)NCBI
Cilp2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249082,325,466 - 2,332,510 (+)NCBI

Position Markers
AA407300  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,880,611 - 69,880,696UniSTSGRCm38
MGSCv37872,404,510 - 72,404,595UniSTSGRCm37
Celera872,439,327 - 72,439,412UniSTS
Cytogenetic Map8B3.3UniSTS
Whitehead/MRC_RH8736.65UniSTS
RH124587  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,880,437 - 69,880,699UniSTSGRCm38
MGSCv37872,404,336 - 72,404,598UniSTSGRCm37
Celera872,439,153 - 72,439,415UniSTS
Cytogenetic Map8B3.3UniSTS
Cilp2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,883,157 - 69,884,318UniSTSGRCm38
Celera872,441,873 - 72,443,034UniSTS
Cytogenetic Map8B3.3UniSTS
cM Map834.01UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:196
Count of miRNA genes:157
Interacting mature miRNAs:177
Transcripts:ENSMUST00000057831
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000057831   ⟹   ENSMUSP00000061544
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl869,880,369 - 69,887,687 (-)Ensembl
RefSeq Acc Id: NM_026818   ⟹   NP_081094
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,333,016 - 70,340,042 (-)NCBI
GRCm38869,880,366 - 69,887,392 (-)ENTREZGENE
MGSCv37872,404,265 - 72,411,291 (-)RGD
Celera872,439,082 - 72,446,108 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_081094 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAE43158 (Get FASTA)   NCBI Sequence Viewer  
  D3Z7H8 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_081094   ⟸   NM_026818
- Peptide Label: precursor
- UniProtKB: D3Z7H8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000061544   ⟸   ENSMUST00000057831
Protein Domains
Ig-like C2-type   TSP type-1

Promoters
RGD ID:8667249
Promoter ID:EPDNEW_M11656
Type:single initiation site
Name:Cilp2_1
Description:Mus musculus cartilage intermediate layer protein 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38869,887,394 - 69,887,454EPDNEW
RGD ID:6843894
Promoter ID:MM_KWN:54647
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney,   Lung
Transcripts:ENSMUST00000057831,   OTTMUST00000085596
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,411,206 - 72,413,017 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915959 AgrOrtholog
Ensembl Genes ENSMUSG00000044006 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000061544 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000057831 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.20.100.10 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
InterPro Carb-bd-like_fold UniProtKB/Swiss-Prot
  CILP1/CILP2 UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  TSP1_rpt UniProtKB/Swiss-Prot
  TSP1_rpt_sf UniProtKB/Swiss-Prot
  WxxW_domain UniProtKB/Swiss-Prot
KEGG Report mmu:68709 UniProtKB/Swiss-Prot
MGD MGI:1915959 ENTREZGENE
NCBI Gene 68709 ENTREZGENE
PANTHER PTHR15031 UniProtKB/Swiss-Prot
Pfam Mucin2_WxxW UniProtKB/Swiss-Prot
  TSP_1 UniProtKB/Swiss-Prot
PhenoGen Cilp2 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  TSP1 UniProtKB/Swiss-Prot
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
  TSP1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF49452 UniProtKB/Swiss-Prot
  SSF82895 UniProtKB/Swiss-Prot
UniGene Mm.334584 ENTREZGENE
UniProt CILP2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3V4C8_MOUSE UniProtKB/TrEMBL