Derl2 (Der1-like domain family, member 2) - Rat Genome Database

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Gene: Derl2 (Der1-like domain family, member 2) Mus musculus
Analyze
Symbol: Derl2
Name: Der1-like domain family, member 2
RGD ID: 1614978
MGI Page MGI
Description: Predicted to enable misfolded protein binding activity; signal recognition particle binding activity; and ubiquitin-specific protease binding activity. Acts upstream of or within retrograde protein transport, ER to cytosol and suckling behavior. Located in early endosome; endoplasmic reticulum; and late endosome. Is expressed in yolk sac and yolk sac endoderm. Orthologous to human DERL2 (derlin 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BC005682; carcinoma related; CGI-10; CGI-101; degradation in endoplasmic reticulum protein 2; der1-like protein 2; Derl; derlin 2; derlin-2; F; F-; F-lana; Flana; MGC11613; RP23-83I13.8
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,898,266 - 70,910,667 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,897,990 - 70,910,667 (-)EnsemblGRCm39 Ensembl
GRCm381171,007,440 - 71,019,841 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,007,164 - 71,019,841 (-)EnsemblGRCm38mm10GRCm38
MGSCv371170,820,947 - 70,832,765 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,823,640 - 70,835,458 (-)NCBIMGSCv36mm8
Celera1178,561,860 - 78,573,678 (-)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1143.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11318612   PMID:11500051   PMID:12466851   PMID:12477932   PMID:12904583   PMID:14610273  
PMID:15215855   PMID:15306695   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16186509   PMID:16449189   PMID:18799693   PMID:19509052   PMID:21220515   PMID:21267068  
PMID:21873635   PMID:23444373   PMID:24457600   PMID:25009997   PMID:25078082   PMID:27626380   PMID:29167172   PMID:30995221   PMID:32554809   PMID:32858914   PMID:32968282   PMID:34355142  


Genomics

Comparative Map Data
Derl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,898,266 - 70,910,667 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,897,990 - 70,910,667 (-)EnsemblGRCm39 Ensembl
GRCm381171,007,440 - 71,019,841 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,007,164 - 71,019,841 (-)EnsemblGRCm38mm10GRCm38
MGSCv371170,820,947 - 70,832,765 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,823,640 - 70,835,458 (-)NCBIMGSCv36mm8
Celera1178,561,860 - 78,573,678 (-)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1143.21NCBI
DERL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38175,471,254 - 5,486,817 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl175,471,254 - 5,486,811 (-)EnsemblGRCh38hg38GRCh38
GRCh37175,374,574 - 5,389,498 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36175,318,337 - 5,330,221 (-)NCBINCBI36Build 36hg18NCBI36
Build 34175,318,336 - 5,330,218NCBI
Celera175,393,985 - 5,405,873 (-)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef175,268,081 - 5,279,745 (-)NCBIHuRef
CHM1_1175,387,294 - 5,399,165 (-)NCBICHM1_1
T2T-CHM13v2.0175,364,997 - 5,380,235 (-)NCBIT2T-CHM13v2.0
Derl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81056,226,340 - 56,238,038 (-)NCBIGRCr8
mRatBN7.21055,727,764 - 55,739,442 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1055,727,643 - 55,739,518 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1060,407,453 - 60,419,059 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01059,895,972 - 59,907,578 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01055,395,062 - 55,406,668 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01057,641,682 - 57,653,554 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,644,207 - 57,653,359 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01057,386,894 - 57,398,868 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1054,873,447 - 54,885,319 (-)NCBICelera
Cytogenetic Map10q24NCBI
Derl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,825,341 - 10,837,328 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,824,922 - 10,837,408 (-)NCBIChiLan1.0ChiLan1.0
DERL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21913,084,405 - 13,096,337 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11715,049,592 - 15,064,585 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0175,519,183 - 5,534,145 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1175,514,440 - 5,526,363 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl175,514,440 - 5,526,363 (-)Ensemblpanpan1.1panPan2
DERL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1531,319,660 - 31,330,846 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl531,319,717 - 31,330,841 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha531,457,816 - 31,468,997 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0531,424,427 - 31,435,599 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl531,424,475 - 31,435,594 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1531,389,973 - 31,401,157 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0531,348,892 - 31,360,075 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0531,525,284 - 31,536,488 (+)NCBIUU_Cfam_GSD_1.0
Derl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560253,558,913 - 53,572,084 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366772,328,904 - 2,342,080 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366772,328,783 - 2,342,068 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DERL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1251,507,996 - 51,524,793 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11251,508,138 - 51,524,799 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DERL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,882,296 - 4,897,799 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,881,876 - 4,898,078 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605916,689,748 - 16,705,481 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Derl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,274,302 - 9,285,288 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,274,302 - 9,285,645 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Derl2
16 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1379
Count of miRNA genes:660
Interacting mature miRNAs:821
Transcripts:ENSMUST00000018586, ENSMUST00000108523, ENSMUST00000131340, ENSMUST00000132198, ENSMUST00000140712, ENSMUST00000143850, ENSMUST00000171041
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse

Markers in Region
UniSTS:236628  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381171,010,048 - 71,010,142UniSTSGRCm38
MGSCv371170,823,550 - 70,823,644UniSTSGRCm37
Celera1178,564,463 - 78,564,557UniSTS
Cytogenetic Map11B4UniSTS
cM Map1142.0UniSTS
D11Die14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381171,017,389 - 71,017,502UniSTSGRCm38
MGSCv371170,830,891 - 70,831,004UniSTSGRCm37
Celera1178,571,804 - 78,571,917UniSTS
Cytogenetic Map11B4UniSTS
cM Map11 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001291146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_033562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017314227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF208064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE627680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB526064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR936847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000018586   ⟹   ENSMUSP00000136261
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,901,177 - 70,910,095 (-)Ensembl
GRCm38.p6 Ensembl1171,010,351 - 71,019,269 (-)Ensembl
RefSeq Acc Id: ENSMUST00000108523   ⟹   ENSMUSP00000104163
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,897,990 - 70,910,068 (-)Ensembl
GRCm38.p6 Ensembl1171,007,164 - 71,019,242 (-)Ensembl
RefSeq Acc Id: ENSMUST00000131340   ⟹   ENSMUSP00000135984
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,905,392 - 70,910,038 (-)Ensembl
GRCm38.p6 Ensembl1171,014,566 - 71,019,212 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132198   ⟹   ENSMUSP00000136401
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,903,948 - 70,910,101 (-)Ensembl
GRCm38.p6 Ensembl1171,013,122 - 71,019,275 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140712
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,902,948 - 70,910,069 (-)Ensembl
GRCm38.p6 Ensembl1171,012,122 - 71,019,243 (-)Ensembl
RefSeq Acc Id: ENSMUST00000143850   ⟹   ENSMUSP00000117052
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,898,268 - 70,910,129 (-)Ensembl
GRCm38.p6 Ensembl1171,007,442 - 71,019,303 (-)Ensembl
RefSeq Acc Id: ENSMUST00000171041   ⟹   ENSMUSP00000127568
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,900,759 - 70,910,667 (-)Ensembl
GRCm38.p6 Ensembl1171,009,933 - 71,019,841 (-)Ensembl
RefSeq Acc Id: NM_001291146   ⟹   NP_001278075
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,898,266 - 70,910,667 (-)NCBI
GRCm381171,007,440 - 71,019,841 (-)NCBI
Celera1178,561,855 - 78,574,256 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001291147   ⟹   NP_001278076
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,898,266 - 70,910,129 (-)NCBI
GRCm381171,007,440 - 71,019,303 (-)NCBI
Celera1178,561,855 - 78,574,256 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001291148   ⟹   NP_001278077
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,898,266 - 70,910,129 (-)NCBI
GRCm381171,007,440 - 71,019,303 (-)NCBI
Celera1178,561,855 - 78,574,256 (-)NCBI
Sequence:
RefSeq Acc Id: NM_033562   ⟹   NP_291040
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,898,266 - 70,910,129 (-)NCBI
GRCm381171,007,440 - 71,019,303 (-)NCBI
MGSCv371170,820,947 - 70,832,765 (-)RGD
Celera1178,561,855 - 78,574,256 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017314227   ⟹   XP_017169716
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,903,961 - 70,910,197 (-)NCBI
GRCm381171,013,135 - 71,019,378 (-)NCBI
Sequence:
RefSeq Acc Id: NP_291040   ⟸   NM_033562
- Peptide Label: isoform a
- UniProtKB: Q920I5 (UniProtKB/Swiss-Prot),   Q99J12 (UniProtKB/Swiss-Prot),   Q8BNI4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001278075   ⟸   NM_001291146
- Peptide Label: isoform b
- UniProtKB: Q3U957 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278077   ⟸   NM_001291148
- Peptide Label: isoform c
- UniProtKB: Q8BNI4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001278076   ⟸   NM_001291147
- Peptide Label: isoform b
- UniProtKB: Q3U957 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017169716   ⟸   XM_017314227
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000117052   ⟸   ENSMUST00000143850
RefSeq Acc Id: ENSMUSP00000104163   ⟸   ENSMUST00000108523
RefSeq Acc Id: ENSMUSP00000136401   ⟸   ENSMUST00000132198
RefSeq Acc Id: ENSMUSP00000127568   ⟸   ENSMUST00000171041
RefSeq Acc Id: ENSMUSP00000135984   ⟸   ENSMUST00000131340
RefSeq Acc Id: ENSMUSP00000136261   ⟸   ENSMUST00000018586

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BNI4-F1-model_v2 AlphaFold Q8BNI4 1-239 view protein structure

Promoters
RGD ID:6820715
Promoter ID:MM_KWN:8272
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000013718,   OTTMUST00000013720,   OTTMUST00000013721,   OTTMUST00000013722,   OTTMUST00000013723,   OTTMUST00000013724,   OTTMUST00000013725,   OTTMUST00000013727,   OTTMUST00000013728,   OTTMUST00000013729,   UC007JXI.1,   UC007JXK.1,   UC007JXL.1,   UC007JXN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361170,832,626 - 70,833,462 (-)MPROMDB
RGD ID:8675388
Promoter ID:EPDNEW_M15725
Type:multiple initiation site
Name:Derl2_1
Description:Mus musculus Der1-like domain family, member 2 , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15727  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381171,019,252 - 71,019,312EPDNEW
RGD ID:8675392
Promoter ID:EPDNEW_M15727
Type:single initiation site
Name:Derl2_2
Description:Mus musculus Der1-like domain family, member 2 , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15725  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381171,019,789 - 71,019,849EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2151483 AgrOrtholog
Ensembl Genes ENSMUSG00000018442 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000018586.6 UniProtKB/TrEMBL
  ENSMUST00000108523.10 UniProtKB/Swiss-Prot
  ENSMUST00000131340.2 UniProtKB/TrEMBL
  ENSMUST00000132198.8 UniProtKB/TrEMBL
  ENSMUST00000143850 ENTREZGENE
  ENSMUST00000143850.8 UniProtKB/Swiss-Prot
  ENSMUST00000171041 ENTREZGENE
  ENSMUST00000171041.8 UniProtKB/TrEMBL
InterPro DER1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhomboid-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:116891 UniProtKB/Swiss-Prot
MGD MGI:2151483 ENTREZGENE
NCBI Gene 116891 ENTREZGENE
PANTHER DER1-LIKE PROTEIN, DERLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DERLIN-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DER1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Derl2 PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
Superfamily-SCOP SSF144091 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DERL2_MOUSE UniProtKB/Swiss-Prot
  J3KMR6_MOUSE UniProtKB/TrEMBL
  J3QMF4_MOUSE UniProtKB/TrEMBL
  J3QMQ7_MOUSE UniProtKB/TrEMBL
  Q3U957 ENTREZGENE, UniProtKB/TrEMBL
  Q8BNI4 ENTREZGENE
  Q920I5 ENTREZGENE
  Q99J12 ENTREZGENE
UniProt Secondary Q920I5 UniProtKB/Swiss-Prot
  Q99J12 UniProtKB/Swiss-Prot