Myocd (myocardin) - Rat Genome Database

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Gene: Myocd (myocardin) Mus musculus
Analyze
Symbol: Myocd
Name: myocardin
RGD ID: 1614957
MGI Page MGI
Description: Enables several functions, including R-SMAD binding activity; enzyme binding activity; and transcription coactivator activity. Involved in several processes, including circulatory system development; positive regulation of macromolecule biosynthetic process; and regulation of signal transduction. Acts upstream of or within several processes, including circulatory system development; negative regulation of cardiac muscle cell apoptotic process; and regulation of DNA-templated transcription. Located in nucleus. Part of chromatin. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; paraxial mesenchyme; and respiratory system. Used to study congenital megabladder; dilated cardiomyopathy; and patent ductus arteriosus. Human ortholog(s) of this gene implicated in congenital megabladder. Orthologous to human MYOCD (myocardin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: basic SAP coiled-coil transcription activator 2; BSAC2A; Sr; SRF co-factor protein (cardiac and smooth muscle); SRF cofactor protein; Srfcp
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391165,064,434 - 65,160,821 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1165,067,387 - 65,160,815 (-)EnsemblGRCm39 Ensembl
GRCm381165,173,608 - 65,269,989 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,176,561 - 65,269,989 (-)EnsemblGRCm38mm10GRCm38
MGSCv371164,990,063 - 65,083,491 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361164,992,756 - 65,086,175 (-)NCBIMGSCv36mm8
Celera1172,112,506 - 72,207,425 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cardiac muscle cell apoptotic process  (IMP)
cardiac muscle cell differentiation  (IBA,IMP)
cardiac muscle cell myoblast differentiation  (ISO)
cardiac vascular smooth muscle cell differentiation  (ISO)
cardiac ventricle development  (IMP)
cell growth involved in cardiac muscle cell development  (ISO)
cellular component maintenance  (IMP)
cellular response to angiotensin  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to hypoxia  (ISO)
chromatin organization  (IDA)
digestive tract development  (IMP)
ductus arteriosus closure  (IMP)
heart development  (IDA,IMP)
hepatic stellate cell activation  (ISO)
lung alveolus development  (IMP)
negative regulation of amyloid-beta clearance  (ISO)
negative regulation of cardiac muscle cell apoptotic process  (IMP)
negative regulation of cell adhesion molecule production  (IDA)
negative regulation of cell population proliferation  (ISO)
negative regulation of myotube differentiation  (IMP)
negative regulation of platelet-derived growth factor receptor-beta signaling pathway  (IDA)
negative regulation of skeletal muscle cell differentiation  (ISO)
negative regulation of transcription by RNA polymerase II  (IGI)
negative regulation of vascular associated smooth muscle cell migration  (IDA)
negative regulation of vascular associated smooth muscle cell proliferation  (IDA)
positive regulation of cardiac muscle cell differentiation  (ISO)
positive regulation of cell population proliferation  (IDA)
positive regulation of DNA-templated transcription  (IDA,ISO)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of gene expression  (IDA)
positive regulation of miRNA transcription  (IDA)
positive regulation of smooth muscle cell differentiation  (ISO)
positive regulation of smooth muscle contraction  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IGI,ISO)
positive regulation of transforming growth factor beta receptor signaling pathway  (IDA)
positive regulation of vascular associated smooth muscle cell migration  (ISO)
regulation of cell growth by extracellular stimulus  (IDA)
regulation of myoblast differentiation  (IMP)
regulation of phenotypic switching  (IGI)
regulation of smooth muscle cell differentiation  (ISO)
regulation of transcription by RNA polymerase II  (IDA)
response to hypoxia  (ISO)
response to mechanical stimulus  (ISO)
response to muscle stretch  (ISO)
smooth muscle cell differentiation  (IBA,IMP,ISO)
transcription by RNA polymerase II  (IGI)
transcription initiation-coupled chromatin remodeling  (IDA)
urinary bladder development  (IMP,ISO)
uterus development  (IMP)
vascular associated smooth muscle cell differentiation  (IGI)
vasculogenesis  (IMP)
ventricular cardiac muscle cell differentiation  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Myocardin regulates BMP10 expression and is required for heart development. Huang J, etal., J Clin Invest. 2012 Oct;122(10):3678-91. doi: 10.1172/JCI63635. Epub 2012 Sep 17.
2. Myocardin is required for cardiomyocyte survival and maintenance of heart function. Huang J, etal., Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18734-9. doi: 10.1073/pnas.0910749106. Epub 2009 Oct 22.
3. Effects of flavonoids on MicroRNA 145 regulation through Klf4 and myocardin in neointimal formation in vitro and in vivo. Lin CM, etal., J Nutr Biochem. 2018 Feb;52:27-35. doi: 10.1016/j.jnutbio.2017.08.016. Epub 2017 Sep 14.
4. Myocardin ablation in a cardiac-renal rat model. Mittal A, etal., Sci Rep. 2019 Apr 10;9(1):5872. doi: 10.1038/s41598-019-42009-z.
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Myocardin mRNA is augmented in the failing myocardium: expression profiling in the porcine model and human dilated cardiomyopathy. Torrado M, etal., J Mol Med (Berl). 2003 Sep;81(9):566-77. doi: 10.1007/s00109-003-0470-7. Epub 2003 Aug 13.
10. Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells. Xia XD, etal., Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Apr;1866(4):158824. doi: 10.1016/j.bbalip.2020.158824. Epub 2020 Oct 7.
11. Regulation of smooth muscle contractility by competing endogenous mRNAs in intracranial aneurysms. Zhang M, etal., J Neuropathol Exp Neurol. 2015 May;74(5):411-24. doi: 10.1097/NEN.0000000000000185.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11439182   PMID:11511353   PMID:12397177   PMID:12466851   PMID:12477932   PMID:12640126   PMID:12663482   PMID:12756293  
PMID:12858529   PMID:12867591   PMID:14645524   PMID:14645532   PMID:15016729   PMID:15044015   PMID:15169892   PMID:15231515   PMID:15331365   PMID:15601857   PMID:15618518   PMID:15634680  
PMID:15657056   PMID:15767668   PMID:15798203   PMID:15929941   PMID:16141072   PMID:16141073   PMID:16204380   PMID:16224064   PMID:16310178   PMID:16818234   PMID:17021041   PMID:17030628  
PMID:17215356   PMID:17292825   PMID:17360478   PMID:17363709   PMID:17585069   PMID:17940050   PMID:17991879   PMID:18025109   PMID:18188448   PMID:18203678   PMID:18296632   PMID:18316483  
PMID:18511849   PMID:18776146   PMID:18945672   PMID:19097117   PMID:19342595   PMID:19578358   PMID:19619540   PMID:19620969   PMID:19705442   PMID:19706423   PMID:19776005   PMID:19797053  
PMID:19801679   PMID:20019329   PMID:20059953   PMID:20167605   PMID:20211142   PMID:20378849   PMID:20385216   PMID:20484220   PMID:20564193   PMID:20566642   PMID:20881014   PMID:21051663  
PMID:21267068   PMID:21305474   PMID:21357509   PMID:21402709   PMID:21423180   PMID:21506120   PMID:21677750   PMID:21693521   PMID:21704027   PMID:21708977   PMID:21779394   PMID:21873635  
PMID:21897873   PMID:21979435   PMID:21984848   PMID:22075245   PMID:22342504   PMID:22580282   PMID:22615115   PMID:22772757   PMID:22833126   PMID:22843699   PMID:22863011   PMID:22884695  
PMID:23007391   PMID:23103763   PMID:23144723   PMID:23308271   PMID:23359472   PMID:23449535   PMID:23641053   PMID:23645682   PMID:23671695   PMID:23704920   PMID:23825366   PMID:23946491  
PMID:24068960   PMID:24106278   PMID:24133205   PMID:24248596   PMID:24252873   PMID:24335282   PMID:24478334   PMID:24705356   PMID:24855642   PMID:25100730   PMID:25109772   PMID:25127126  
PMID:25139858   PMID:25174608   PMID:25573853   PMID:25614278   PMID:25631042   PMID:25805819   PMID:25957400   PMID:26020233   PMID:26057579   PMID:26077572   PMID:26105053   PMID:26221073  
PMID:26244347   PMID:26321200   PMID:26453897   PMID:26930384   PMID:27174098   PMID:27403897   PMID:27736991   PMID:28195173   PMID:28334964   PMID:28342289   PMID:28342807   PMID:28351867  
PMID:28538179   PMID:28574994   PMID:28655168   PMID:28797033   PMID:28943241   PMID:28952437   PMID:29093270   PMID:29114040   PMID:29295976   PMID:29367466   PMID:29482449   PMID:29511336  
PMID:29555813   PMID:29976770   PMID:30153454   PMID:30478225   PMID:30649340   PMID:30796970   PMID:30916783   PMID:31024075   PMID:31024170   PMID:31029421   PMID:31167144   PMID:31513549  
PMID:31634485   PMID:31928221   PMID:31982428   PMID:32142630   PMID:33743134   PMID:34523259   PMID:34671097   PMID:34694145   PMID:34963058   PMID:35103284   PMID:35246800   PMID:35597154  
PMID:35905011   PMID:36094016   PMID:36484734   PMID:36610028   PMID:37289107   PMID:37615725   PMID:37642238   PMID:38014633   PMID:38110169  


Genomics

Comparative Map Data
Myocd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391165,064,434 - 65,160,821 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1165,067,387 - 65,160,815 (-)EnsemblGRCm39 Ensembl
GRCm381165,173,608 - 65,269,989 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,176,561 - 65,269,989 (-)EnsemblGRCm38mm10GRCm38
MGSCv371164,990,063 - 65,083,491 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361164,992,756 - 65,086,175 (-)NCBIMGSCv36mm8
Celera1172,112,506 - 72,207,425 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.42NCBI
MYOCD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381712,665,890 - 12,768,949 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1712,665,890 - 12,768,949 (+)EnsemblGRCh38hg38GRCh38
GRCh371712,569,207 - 12,672,266 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361712,510,231 - 12,607,686 (+)NCBINCBI36Build 36hg18NCBI36
Build 341712,510,230 - 12,607,686NCBI
Celera1712,594,549 - 12,695,987 (+)NCBICelera
Cytogenetic Map17p12NCBI
HuRef1712,464,600 - 12,566,080 (+)NCBIHuRef
CHM1_11712,577,982 - 12,679,406 (+)NCBICHM1_1
T2T-CHM13v2.01712,573,362 - 12,676,444 (+)NCBIT2T-CHM13v2.0
Myocd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81050,332,356 - 50,426,819 (-)NCBIGRCr8
mRatBN7.21049,833,219 - 49,928,806 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1049,836,641 - 49,927,627 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1054,505,304 - 54,596,319 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01053,995,291 - 54,086,296 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01049,509,995 - 49,600,991 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01051,682,053 - 51,781,458 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1051,683,540 - 51,778,986 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01051,439,727 - 51,534,567 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41051,496,223 - 51,588,226 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11051,509,851 - 51,601,849 (-)NCBI
Celera1049,052,568 - 49,143,747 (-)NCBICelera
Cytogenetic Map10q24NCBI
Myocd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554674,656,380 - 4,743,110 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554674,653,065 - 4,743,438 (-)NCBIChiLan1.0ChiLan1.0
MYOCD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21960,982,668 - 61,082,874 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11765,789,278 - 65,889,518 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01738,880,120 - 38,983,246 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11743,578,967 - 43,681,659 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1743,584,259 - 43,681,659 (-)Ensemblpanpan1.1panPan2
MYOCD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1536,674,476 - 36,774,435 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl536,674,300 - 36,769,327 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha536,774,863 - 36,918,323 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0536,738,753 - 36,883,183 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl536,782,154 - 36,879,172 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1536,711,643 - 36,856,024 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0536,659,301 - 36,802,936 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0536,843,479 - 36,993,391 (+)NCBIUU_Cfam_GSD_1.0
Myocd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560251,782,304 - 51,881,336 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365955,256,785 - 5,351,723 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365955,256,615 - 5,356,563 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYOCD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1256,931,317 - 57,029,258 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11256,931,628 - 57,029,258 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21259,928,695 - 59,945,526 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYOCD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11611,923,464 - 12,100,897 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1612,000,197 - 12,095,552 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660599,137,934 - 9,239,568 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myocd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624877618,789 - 647,471 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myocd
3881 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1697
Count of miRNA genes:537
Interacting mature miRNAs:674
Transcripts:ENSMUST00000101042, ENSMUST00000102635, ENSMUST00000108695, ENSMUST00000144399, ENSMUST00000150823, ENSMUST00000151483
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115406567067078411Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115408094165103841Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115925661769482699Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
4141642Ltxs2_mlethal factor toxin susceptibility 2 (mouse)Not determined116304211368500330Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse

Markers in Region
D11Mit177  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,212,885 - 65,213,015UniSTSGRCm38
MGSCv371165,026,387 - 65,026,517UniSTSGRCm37
Celera1172,150,313 - 72,150,429UniSTS
Cytogenetic Map11B3UniSTS
cM Map1136.0UniSTS
Whitehead Genetic1133.9UniSTS
Whitehead/MRC_RH11855.46UniSTS
Whitehead_YAC11 UniSTS
Myocd  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,178,448 - 65,178,889UniSTSGRCm38
MGSCv371164,991,950 - 64,992,391UniSTSGRCm37
Celera1172,114,397 - 72,114,838UniSTS
Cytogenetic Map11B3UniSTS
cM Map11 UniSTS
PMC150745P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,187,027 - 65,187,135UniSTSGRCm38
MGSCv371165,000,529 - 65,000,637UniSTSGRCm37
Celera1172,122,963 - 72,123,071UniSTS
Cytogenetic Map11B3UniSTS
PMC309615P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,187,392 - 65,187,685UniSTSGRCm38
MGSCv371165,000,894 - 65,001,187UniSTSGRCm37
Celera1172,123,328 - 72,123,621UniSTS
Cytogenetic Map11B3UniSTS
PMC309615P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381165,184,488 - 65,184,631UniSTSGRCm38
MGSCv371164,997,990 - 64,998,133UniSTSGRCm37
Celera1172,120,424 - 72,120,567UniSTS
Cytogenetic Map11B3UniSTS
Myocd  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B3UniSTS
Myocd  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B3UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000101042   ⟹   ENSMUSP00000098603
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1165,069,254 - 65,109,385 (-)Ensembl
GRCm38.p6 Ensembl1165,178,428 - 65,218,559 (-)Ensembl
RefSeq Acc Id: ENSMUST00000102635   ⟹   ENSMUSP00000099695
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1165,067,387 - 65,160,767 (-)Ensembl
GRCm38.p6 Ensembl1165,176,561 - 65,269,941 (-)Ensembl
RefSeq Acc Id: ENSMUST00000108695   ⟹   ENSMUSP00000104335
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1165,067,400 - 65,160,815 (-)Ensembl
GRCm38.p6 Ensembl1165,176,574 - 65,269,989 (-)Ensembl
RefSeq Acc Id: ENSMUST00000144399   ⟹   ENSMUSP00000115572
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1165,086,928 - 65,096,293 (-)Ensembl
GRCm38.p6 Ensembl1165,196,102 - 65,205,467 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150823
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1165,114,560 - 65,160,680 (-)Ensembl
GRCm38.p6 Ensembl1165,223,734 - 65,269,854 (-)Ensembl
RefSeq Acc Id: ENSMUST00000151483
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1165,067,599 - 65,072,983 (-)Ensembl
GRCm38.p6 Ensembl1165,176,773 - 65,182,157 (-)Ensembl
RefSeq Acc Id: NM_145136   ⟹   NP_660118
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391165,064,434 - 65,160,821 (-)NCBI
GRCm381165,176,561 - 65,269,989 (-)NCBI
MGSCv371164,990,063 - 65,083,491 (-)RGD
Celera1172,112,506 - 72,207,425 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_146386   ⟹   NP_666498
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391165,064,434 - 65,160,821 (-)NCBI
GRCm381165,176,561 - 65,269,989 (-)NCBI
MGSCv371164,990,063 - 65,083,491 (-)RGD
Celera1172,112,506 - 72,207,425 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011248893   ⟹   XP_011247195
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391165,064,434 - 65,160,630 (-)NCBI
GRCm381165,173,608 - 65,269,804 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011248895   ⟹   XP_011247197
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391165,064,434 - 65,160,488 (-)NCBI
GRCm381165,173,608 - 65,269,662 (-)NCBI
Sequence:
RefSeq Acc Id: NP_660118   ⟸   NM_145136
- Peptide Label: isoform A
- UniProtKB: B9EJ16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_666498   ⟸   NM_146386
- Peptide Label: isoform B
- UniProtKB: Q8C3W6 (UniProtKB/Swiss-Prot),   Q6W8X1 (UniProtKB/Swiss-Prot),   Q5SS65 (UniProtKB/Swiss-Prot),   Q8VIL4 (UniProtKB/Swiss-Prot),   Q8VIM5 (UniProtKB/Swiss-Prot),   B9EJ16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247197   ⟸   XM_011248895
- Peptide Label: isoform X2
- UniProtKB: B9EJ16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247195   ⟸   XM_011248893
- Peptide Label: isoform X1
- UniProtKB: B9EJ16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000115572   ⟸   ENSMUST00000144399
RefSeq Acc Id: ENSMUSP00000098603   ⟸   ENSMUST00000101042
RefSeq Acc Id: ENSMUSP00000104335   ⟸   ENSMUST00000108695
RefSeq Acc Id: ENSMUSP00000099695   ⟸   ENSMUST00000102635
Protein Domains
SAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VIM5-F1-model_v2 AlphaFold Q8VIM5 1-935 view protein structure

Promoters
RGD ID:8675038
Promoter ID:EPDNEW_M15550
Type:multiple initiation site
Name:Myocd_1
Description:Mus musculus myocardin , transcript variant B, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381165,269,995 - 65,270,055EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2137495 AgrOrtholog
Ensembl Genes ENSMUSG00000020542 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000101042 ENTREZGENE
  ENSMUST00000101042.9 UniProtKB/Swiss-Prot
  ENSMUST00000102635 ENTREZGENE
  ENSMUST00000102635.10 UniProtKB/Swiss-Prot
  ENSMUST00000108695 ENTREZGENE
  ENSMUST00000108695.9 UniProtKB/Swiss-Prot
  ENSMUST00000144399.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.720.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.140.2040 UniProtKB/Swiss-Prot
  6.10.150.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Myocardin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RPEL_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:214384 UniProtKB/Swiss-Prot
MGD MGI:2137495 ENTREZGENE
NCBI Gene 214384 ENTREZGENE
PANTHER PTHR22793 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22793:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RPEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myocd PhenoGen
PROSITE RPEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RPEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF68906 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B9EJ16 ENTREZGENE, UniProtKB/TrEMBL
  F6TBX6_MOUSE UniProtKB/TrEMBL
  MYCD_MOUSE UniProtKB/Swiss-Prot
  Q3US93_MOUSE UniProtKB/TrEMBL
  Q5SS65 ENTREZGENE
  Q6W8X1 ENTREZGENE
  Q8C3W6 ENTREZGENE
  Q8VIL4 ENTREZGENE
  Q8VIM5 ENTREZGENE
UniProt Secondary Q5SS65 UniProtKB/Swiss-Prot
  Q6W8X1 UniProtKB/Swiss-Prot
  Q8C3W6 UniProtKB/Swiss-Prot
  Q8VIL4 UniProtKB/Swiss-Prot