Shisa6 (shisa family member 6) - Rat Genome Database
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Gene: Shisa6 (shisa family member 6) Mus musculus
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Symbol: Shisa6
Name: shisa family member 6
RGD ID: 1614798
MGI Page MGI
Description: Is expressed in central nervous system. Orthologous to human SHISA6 (shisa family member 6); INTERACTS WITH 1,2-dichloroethane; 4,4'-sulfonyldiphenol; diclofenac.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CKAMP; ckamp52; cysteine-knot AMPAR-modulating protein 52; cystine-knot AMPAR modulating protein of 52 kDa; Gm879; protein shisa-6 homolog; shisa homolog 6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391166,102,551 - 66,418,715 (-)NCBIGRCm39mm39
GRCm39 Ensembl1166,102,551 - 66,416,790 (-)Ensembl
GRCm381166,211,725 - 66,527,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1166,211,725 - 66,525,964 (-)EnsemblGRCm38mm10GRCm38
MGSCv371166,025,227 - 66,339,628 (-)NCBIGRCm37mm9NCBIm37
MGSCv361166,027,924 - 66,342,321 (-)NCBImm8
Celera1173,147,659 - 73,459,932 (-)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:19554387   PMID:21267068   PMID:21873635   PMID:22632720  
PMID:25556833   PMID:26623514   PMID:26931375   PMID:28196692   PMID:28706196   PMID:32325033  


Genomics

Comparative Map Data
Shisa6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391166,102,551 - 66,418,715 (-)NCBIGRCm39mm39
GRCm39 Ensembl1166,102,551 - 66,416,790 (-)Ensembl
GRCm381166,211,725 - 66,527,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1166,211,725 - 66,525,964 (-)EnsemblGRCm38mm10GRCm38
MGSCv371166,025,227 - 66,339,628 (-)NCBIGRCm37mm9NCBIm37
MGSCv361166,027,924 - 66,342,321 (-)NCBImm8
Celera1173,147,659 - 73,459,932 (-)NCBICelera
Cytogenetic Map11B3NCBI
SHISA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1711,241,213 - 11,564,063 (+)EnsemblGRCh38hg38GRCh38
GRCh381711,241,213 - 11,564,063 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371711,144,530 - 11,467,380 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361711,085,465 - 11,402,921 (+)NCBINCBI36hg18NCBI36
Celera1711,175,533 - 11,498,055 (+)NCBI
Cytogenetic Map17p12NCBI
HuRef1711,046,153 - 11,369,076 (+)NCBIHuRef
CHM1_11711,154,593 - 11,476,588 (+)NCBICHM1_1
Shisa6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21050,897,740 - 51,192,413 (-)NCBI
Rnor_6.0 Ensembl1052,749,846 - 53,037,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01052,744,069 - 53,037,853 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01052,498,328 - 52,791,670 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41052,896,362 - 53,190,809 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1050,092,476 - 50,378,235 (-)NCBICelera
Cytogenetic Map10q24NCBI
Shisa6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554675,707,561 - 5,998,910 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554675,701,521 - 5,998,910 (-)NCBIChiLan1.0ChiLan1.0
SHISA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11744,831,076 - 45,154,237 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1744,836,825 - 45,154,241 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01740,081,234 - 40,405,916 (-)NCBIMhudiblu_PPA_v0panPan3
SHISA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl535,424,242 - 35,707,012 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1535,420,981 - 35,701,654 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LOC101959444
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365953,973,099 - 4,152,706 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHISA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11255,757,837 - 56,024,760 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21258,849,892 - 58,898,751 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SHISA6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11610,584,375 - 10,913,012 (+)NCBI
Shisa6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478613,697,178 - 14,007,891 (+)NCBI

Position Markers
D11Mit193  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381166,337,519 - 66,337,653UniSTSGRCm38
MGSCv371166,151,021 - 66,151,155UniSTSGRCm37
Celera1173,275,289 - 73,275,421UniSTS
Cytogenetic Map11B3UniSTS
cM Map1136.0UniSTS
Whitehead Genetic1133.9UniSTS
Whitehead_YAC11 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115936579169591873Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
4141642Ltxs2_mlethal factor toxin susceptibility 2 (mouse)Not determined116315128768609504Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3346
Count of miRNA genes:893
Interacting mature miRNAs:1271
Transcripts:ENSMUST00000066679, ENSMUST00000123454, ENSMUST00000134562
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000066679   ⟹   ENSMUSP00000071025
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1166,217,472 - 66,525,964 (-)Ensembl
RefSeq Acc Id: ENSMUST00000123454   ⟹   ENSMUSP00000120862
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1166,211,725 - 66,525,795 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134562
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1166,375,133 - 66,502,814 (-)Ensembl
RefSeq Acc Id: NM_001034874   ⟹   NP_001030046
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391166,102,551 - 66,416,952 (-)NCBI
GRCm381166,211,725 - 66,526,126 (-)ENTREZGENE
MGSCv371166,025,227 - 66,339,628 (-)RGD
Celera1173,147,659 - 73,459,932 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006533619   ⟹   XP_006533682
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391166,102,551 - 66,418,184 (-)NCBI
GRCm381166,211,725 - 66,526,783 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030246098   ⟹   XP_030101958
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391166,102,551 - 66,418,715 (-)NCBI
GRCm381166,211,725 - 66,527,984 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156815   ⟹   XP_036012708
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391166,102,551 - 66,418,184 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001030046   ⟸   NM_001034874
- Peptide Label: precursor
- UniProtKB: Q3UH99 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006533682   ⟸   XM_006533619
- Peptide Label: isoform X1
- UniProtKB: A0A172Q417 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101958   ⟸   XM_030246098
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000071025   ⟸   ENSMUST00000066679
RefSeq Acc Id: ENSMUSP00000120862   ⟸   ENSMUST00000123454
RefSeq Acc Id: XP_036012708   ⟸   XM_036156815
- Peptide Label: isoform X2

Promoters
RGD ID:8675050
Promoter ID:EPDNEW_M15556
Type:single initiation site
Name:Shisa6_1
Description:Mus musculus shisa family member 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381166,526,060 - 66,526,120EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685725 AgrOrtholog
Ensembl Genes ENSMUSG00000053930 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000071025 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000120862 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000066679 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000123454 UniProtKB/TrEMBL
InterPro Shisa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:380702 UniProtKB/Swiss-Prot
MGD MGI:2685725 ENTREZGENE
NCBI Gene 380702 ENTREZGENE
PANTHER PTHR31774 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Shisa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Shisa6 PhenoGen
UniProt A0A172Q410_MOUSE UniProtKB/TrEMBL
  A0A172Q417 ENTREZGENE
  F6VQZ6_MOUSE UniProtKB/TrEMBL
  Q3UH99 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A172Q417 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-10-21 Shisa6  shisa family member 6    shisa homolog 6 (Xenopus laevis)  Symbol and/or name change 5135510 APPROVED