Cby3 (chibby family member 3) - Rat Genome Database

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Gene: Cby3 (chibby family member 3) Mus musculus
Analyze
Symbol: Cby3
Name: chibby family member 3
RGD ID: 1614269
MGI Page MGI
Description: Orthologous to human CBY3 (chibby family member 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700121K02Rik; chibby homolog 3; chibby homolog 3 (Drosophila); protein chibby homolog 3; RP23-121P11.3
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,248,588 - 50,250,529 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,248,588 - 50,250,526 (+)EnsemblGRCm39 Ensembl
GRCm381150,357,761 - 50,359,702 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,354,462 - 50,359,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv371150,161,020 - 50,173,204 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,199,500 - 50,203,125 (+)NCBIMGSCv36mm8
Celera1154,908,187 - 54,920,367 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:38197861  


Genomics

Comparative Map Data
Cby3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,248,588 - 50,250,529 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,248,588 - 50,250,526 (+)EnsemblGRCm39 Ensembl
GRCm381150,357,761 - 50,359,702 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,354,462 - 50,359,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv371150,161,020 - 50,173,204 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,199,500 - 50,203,125 (+)NCBIMGSCv36mm8
Celera1154,908,187 - 54,920,367 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.54NCBI
CBY3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385179,678,560 - 179,681,034 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5179,678,560 - 179,681,034 (-)EnsemblGRCh38hg38GRCh38
GRCh375179,105,561 - 179,108,035 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,038,183 - 179,040,575 (-)NCBINCBI36Build 36hg18NCBI36
Celera5174,729,963 - 174,732,379 (-)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,832,822 - 173,835,238 (-)NCBIHuRef
CHM1_15178,537,979 - 178,540,395 (-)NCBICHM1_1
T2T-CHM13v2.05180,233,744 - 180,236,219 (-)NCBIT2T-CHM13v2.0
Cby3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,179,316 - 35,183,834 (+)NCBIGRCr8
mRatBN7.21034,680,926 - 34,683,176 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,677,770 - 34,682,784 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01035,855,320 - 35,860,266 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,857,797 - 35,860,987 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01035,628,932 - 35,631,726 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,906,660 - 35,910,054 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1034,022,103 - 34,032,290 (+)NCBICelera
Cytogenetic Map10q22NCBI
CBY3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24174,621,634 - 174,624,123 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15172,761,196 - 172,763,662 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05174,832,765 - 174,835,259 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15182,145,122 - 182,148,901 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5182,145,125 - 182,148,896 (-)Ensemblpanpan1.1panPan2
CBY3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1112,014,271 - 2,016,704 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl112,015,695 - 2,016,693 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,137,030 - 2,139,452 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0111,988,572 - 1,990,994 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1111,960,061 - 1,962,483 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0112,038,675 - 2,041,097 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0112,279,415 - 2,281,837 (+)NCBIUU_Cfam_GSD_1.0
Cby3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213119,890,306 - 119,892,267 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367391,097,780 - 1,101,995 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367391,100,021 - 1,101,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBY3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1278,933,852 - 78,936,011 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2280,500,256 - 80,502,355 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CBY3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12381,403,674 - 81,405,505 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607512,760,937 - 12,777,058 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cby3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473342,557,015 - 42,560,952 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cby3
63 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:440
Count of miRNA genes:205
Interacting mature miRNAs:220
Transcripts:ENSMUST00000052596, ENSMUST00000164067
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
13452402Hipmt3_mhippocampal morphometry trait 3 (mouse)114797732550277325Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000052596   ⟹   ENSMUSP00000052281
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,248,588 - 50,250,526 (+)Ensembl
GRCm38.p6 Ensembl1150,357,761 - 50,359,699 (+)Ensembl
RefSeq Acc Id: ENSMUST00000164067   ⟹   ENSMUSP00000131004
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1150,245,289 - 50,250,526 (+)Ensembl
GRCm38.p6 Ensembl1150,354,462 - 50,359,699 (+)Ensembl
RefSeq Acc Id: NM_029691   ⟹   NP_083967
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391150,248,588 - 50,250,529 (+)NCBI
GRCm381150,357,761 - 50,359,702 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_083967 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB24904 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000052281
  ENSMUSP00000052281.3
GenBank Protein Q9CVN6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_083967   ⟸   NM_029691
- UniProtKB: Z4YJN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000052281   ⟸   ENSMUST00000052596
RefSeq Acc Id: ENSMUSP00000131004   ⟸   ENSMUST00000164067

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CVN6-F1-model_v2 AlphaFold Q9CVN6 1-235 view protein structure

Promoters
RGD ID:6848973
Promoter ID:MM_XEF:1039
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   ES_Cell
Transcripts:NM_001164444
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361150,172,721 - 50,173,221 (+)MPROMDB
RGD ID:8674510
Promoter ID:EPDNEW_M15286
Type:multiple initiation site
Name:Cby3_1
Description:RecName: Full=Protein chibby homolog 3;
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381150,357,761 - 50,357,821EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1923903 AgrOrtholog
Ensembl Genes ENSMUSG00000050087 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000052596 ENTREZGENE
  ENSMUST00000052596.3 UniProtKB/TrEMBL
InterPro Chibby_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1923903 ENTREZGENE
NCBI Gene 76653 ENTREZGENE
PANTHER LEUCINE-RICH PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN CHIBBY HOMOLOG 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Chibby UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cby3 PhenoGen
UniProt CBY3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Z4YJN4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q5NCA8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-11-29 Cby3  chibby family member 3    chibby homolog 3 (Drosophila)  Symbol and/or name change 5135510 APPROVED