Krit1 (KRIT1, ankyrin repeat containing) - Rat Genome Database

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Gene: Krit1 (KRIT1, ankyrin repeat containing) Mus musculus
Analyze
Symbol: Krit1
Name: KRIT1, ankyrin repeat containing
RGD ID: 1614252
MGI Page MGI
Description: Predicted to enable microtubule binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in cell redox homeostasis; negative regulation of angiogenesis; and regulation of establishment of cell polarity. Located in cytoplasm. Part of protein-containing complex. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; eye; and reproductive system. Used to study cerebral cavernous malformation. Human ortholog(s) of this gene implicated in cerebral cavernous malformation and cerebral cavernous malformation 1. Orthologous to human KRIT1 (KRIT1 ankyrin repeat containing).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2010007K12Rik; A630036P20Rik; AA432855; AI450393; AI643869; BB155247; BB235701; Ccm1; cerebral cavernous malformations 1 protein homolog; krev interaction trapped 1; krev interaction trapped protein 1; Kri; Krit
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3953,853,156 - 3,894,515 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl53,853,184 - 3,895,564 (+)EnsemblGRCm39 Ensembl
GRCm3853,803,156 - 3,844,515 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl53,803,184 - 3,845,564 (+)EnsemblGRCm38mm10GRCm38
MGSCv3753,803,165 - 3,844,515 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3653,809,195 - 3,847,365 (+)NCBIMGSCv36mm8
Celera53,739,452 - 3,780,804 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map52.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal allantois morphology  (IEA)
abnormal artery morphology  (IAGP)
abnormal blood circulation  (IAGP)
abnormal blood vessel morphology  (IEA)
abnormal blood vessel physiology  (IAGP)
abnormal brain vasculature morphology  (IAGP)
abnormal chorioallantoic fusion  (IEA)
abnormal dorsal aorta morphology  (IAGP)
abnormal embryo size  (IEA)
abnormal embryo turning  (IEA)
abnormal eye morphology  (IEA)
abnormal heart development  (IAGP)
abnormal heart looping  (IEA)
abnormal heart morphology  (IAGP)
abnormal intersomitic artery morphology  (IAGP)
abnormal left-right axis patterning  (IEA)
abnormal myocardial trabeculae morphology  (IAGP)
abnormal neural tube closure  (IEA)
abnormal neural tube morphology  (IEA)
abnormal optic vesicle formation  (IEA)
abnormal otic vesicle morphology  (IEA)
abnormal pericardium morphology  (IEA)
abnormal pharyngeal arch artery morphology  (IAGP)
abnormal pharyngeal arch morphology  (IEA)
abnormal retina vasculature morphology  (IAGP)
abnormal somite shape  (IEA)
abnormal vascular development  (IAGP)
abnormal vascular endothelial cell physiology  (IAGP)
abnormal venule morphology  (IAGP)
abnormal visceral yolk sac morphology  (IAGP)
absent optic nerve  (IEA)
decreased cardiac jelly amount  (IAGP)
decreased grip strength  (IEA)
dilated aorta  (IAGP)
dilated heart atrium  (IAGP)
dilated heart ventricle  (IAGP)
dilated vasculature  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IEA)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality prior to tooth bud stage  (IEA)
enlarged heart  (IEA)
eye lesions  (IAGP)
incomplete embryo turning  (IAGP)
increased circulating alanine transaminase level  (IEA)
increased retina hemangioma incidence  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
pallor  (IEA)
pharyngeal arch artery stenosis  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IEA)
telangiectasia  (IAGP)
thin myocardium  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Integrin inactivators: balancing cellular functions in vitro and in vivo. Bouvard D, etal., Nat Rev Mol Cell Biol. 2013 Jul;14(7):430-42. doi: 10.1038/nrm3599. Epub 2013 May 30.
2. Talins and kindlins: partners in integrin-mediated adhesion. Calderwood DA, etal., Nat Rev Mol Cell Biol. 2013 Aug;14(8):503-17. doi: 10.1038/nrm3624. Epub 2013 Jul 17.
3. Clinical features of cerebral cavernous malformations patients with KRIT1 mutations. Denier C, etal., Ann Neurol 2004 Feb;55(2):213-20.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11161791   PMID:11161805   PMID:11217851   PMID:11342228   PMID:12172908   PMID:12204286   PMID:12466851  
PMID:12477932   PMID:14500367   PMID:14610273   PMID:14697511   PMID:14993192   PMID:15489334   PMID:15509522   PMID:16037064   PMID:16141072   PMID:16141073   PMID:16373645   PMID:16455310  
PMID:16602821   PMID:16712798   PMID:17657516   PMID:18992740   PMID:19151727   PMID:19723774   PMID:20007487   PMID:20308363   PMID:20332120   PMID:20371769   PMID:20616044   PMID:20668652  
PMID:20940147   PMID:21267068   PMID:21490399   PMID:21859843   PMID:21873635   PMID:22898778   PMID:22922362   PMID:22922958   PMID:22970292   PMID:23748444   PMID:23918940   PMID:24194600  
PMID:24291398   PMID:24990152   PMID:25320085   PMID:25625206   PMID:25791711   PMID:26061019   PMID:26612856   PMID:27027284   PMID:27306493   PMID:27513872   PMID:27626380   PMID:28489816  
PMID:28811547   PMID:28970240   PMID:29170092   PMID:30442679   PMID:30728328   PMID:31040226   PMID:31590384   PMID:31746130   PMID:31776290   PMID:31917192   PMID:32502201   PMID:32648916  
PMID:34156031   PMID:35715588   PMID:36107440   PMID:36232456   PMID:36349990   PMID:36465134   PMID:38293758  


Genomics

Comparative Map Data
Krit1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3953,853,156 - 3,894,515 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl53,853,184 - 3,895,564 (+)EnsemblGRCm39 Ensembl
GRCm3853,803,156 - 3,844,515 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl53,803,184 - 3,845,564 (+)EnsemblGRCm38mm10GRCm38
MGSCv3753,803,165 - 3,844,515 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3653,809,195 - 3,847,365 (+)NCBIMGSCv36mm8
Celera53,739,452 - 3,780,804 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map52.26NCBI
KRIT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38792,198,969 - 92,246,100 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl792,197,498 - 92,246,166 (-)EnsemblGRCh38hg38GRCh38
GRCh37791,828,283 - 91,875,414 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36791,666,219 - 91,713,350 (-)NCBINCBI36Build 36hg18NCBI36
Build 34791,472,933 - 91,520,065NCBI
Celera786,532,835 - 86,579,965 (-)NCBICelera
Cytogenetic Map7q21.2NCBI
HuRef786,435,945 - 86,483,492 (-)NCBIHuRef
CHM1_1791,758,320 - 91,805,450 (-)NCBICHM1_1
T2T-CHM13v2.0793,440,257 - 93,487,387 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2791,157,516 - 91,204,647 (-)NCBI
Krit1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8431,253,918 - 31,288,066 (-)NCBIGRCr8
mRatBN7.2430,299,203 - 30,333,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl430,299,203 - 30,333,359 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx435,271,948 - 35,306,096 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0431,198,032 - 31,232,180 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0429,594,018 - 29,628,167 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0427,438,609 - 27,473,150 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl427,438,609 - 27,473,150 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0427,341,835 - 27,376,376 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4427,014,488 - 27,048,636 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera425,724,169 - 25,758,310 (-)NCBICelera
Cytogenetic Map4q13NCBI
Krit1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554329,171,216 - 9,219,946 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554329,168,678 - 9,219,947 (-)NCBIChiLan1.0ChiLan1.0
KRIT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26110,085,447 - 110,131,571 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17158,350,089 - 158,396,176 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0784,197,200 - 84,244,050 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1797,794,527 - 97,841,099 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl797,794,531 - 97,840,895 (-)Ensemblpanpan1.1panPan2
KRIT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11417,836,513 - 17,872,514 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1417,832,625 - 17,872,190 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1417,398,065 - 17,433,896 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01417,643,248 - 17,679,106 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1417,643,248 - 17,679,291 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11417,803,905 - 17,839,882 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01417,516,013 - 17,552,078 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01417,789,641 - 17,825,471 (-)NCBIUU_Cfam_GSD_1.0
Krit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511831,240,278 - 31,280,063 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366212,088,802 - 2,128,657 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366212,088,606 - 2,128,579 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRIT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl972,142,835 - 72,185,661 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1972,143,652 - 72,184,774 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2978,874,130 - 78,913,770 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRIT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12156,770,694 - 56,816,409 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2156,774,487 - 56,816,049 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604247,456,063 - 47,502,978 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Krit1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624809978,789 - 1,039,091 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624809978,391 - 1,036,313 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Krit1
1252 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1862
Count of miRNA genes:555
Interacting mature miRNAs:642
Transcripts:ENSMUST00000080085, ENSMUST00000171023
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141234Pbwg14_mpostnatal body weight growth 14 (mouse)Not determined5121273552Mouse
1301468Eye1_meye weight 1 (mouse)Not determined5121929650Mouse
10412081Bwq13_mbody weight QTL 13 (mouse)Not determined5123606323Mouse
12904958Gmmq8_mgastrocnemius muscle mass QTL 8 (mouse)5129421124Mouse
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined582314434823280Mouse
12738412Lfibq4_mliver fibrosis QTL 4 (mouse)5315000020799180Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse

Markers in Region
BB235701  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3853,818,888 - 3,819,023UniSTSGRCm38
MGSCv3753,818,888 - 3,819,023UniSTSGRCm37
Celera53,755,175 - 3,755,310UniSTS
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
Whitehead/MRC_RH589.25UniSTS
BB155247  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3853,830,790 - 3,830,931UniSTSGRCm38
MGSCv3753,830,790 - 3,830,931UniSTSGRCm37
Celera53,767,078 - 3,767,219UniSTS
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
Whitehead/MRC_RH592.26UniSTS
AI643869  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3853,804,086 - 3,804,181UniSTSGRCm38
MGSCv3753,804,086 - 3,804,181UniSTSGRCm37
Celera53,740,373 - 3,740,468UniSTS
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
Whitehead/MRC_RH589.25UniSTS
AI450393  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3853,842,524 - 3,842,650UniSTSGRCm38
MGSCv3753,842,524 - 3,842,650UniSTSGRCm37
Celera53,778,813 - 3,778,939UniSTS
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
Whitehead/MRC_RH5106.2UniSTS
06.MHAa81T_M13Rev.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3853,805,396 - 3,805,546UniSTSGRCm38
MGSCv3753,805,396 - 3,805,546UniSTSGRCm37
Celera53,741,683 - 3,741,833UniSTS
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
Whitehead_YAC5 UniSTS
13.MMHAP29FRE7.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3853,824,046 - 3,824,211UniSTSGRCm38
MGSCv3753,824,046 - 3,824,211UniSTSGRCm37
Celera53,760,334 - 3,760,499UniSTS
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
Whitehead_YAC5 UniSTS
34.MMHAP5FLD4.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3853,832,644 - 3,832,830UniSTSGRCm38
MGSCv3753,832,644 - 3,832,830UniSTSGRCm37
Celera53,768,932 - 3,769,118UniSTS
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
Whitehead_YAC5 UniSTS
D5Mit406.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5A1UniSTS
Cytogenetic Map6B1-B2UniSTS
cM Map564.0UniSTS
Whitehead Genetic550.3UniSTS
UniSTS:235124  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3853,844,904 - 3,845,150UniSTSGRCm38
MGSCv3753,844,904 - 3,845,150UniSTSGRCm37
Celera53,781,193 - 3,781,439UniSTS
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
Ccm1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5A1UniSTS
cM Map51.1UniSTS
cM Map5 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001170552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_030675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_033173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030254912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC022236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF306509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF310134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY328895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY464945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB591998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB619038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB853405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB855141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC044820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY150935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX220216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF437358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000080085   ⟹   ENSMUSP00000078985
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,853,184 - 3,891,359 (+)Ensembl
GRCm38.p6 Ensembl53,803,184 - 3,841,359 (+)Ensembl
RefSeq Acc Id: ENSMUST00000171023   ⟹   ENSMUSP00000132375
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,853,405 - 3,894,303 (+)Ensembl
GRCm38.p6 Ensembl53,803,405 - 3,844,303 (+)Ensembl
RefSeq Acc Id: ENSMUST00000196098
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,855,293 - 3,861,509 (+)Ensembl
GRCm38.p6 Ensembl53,805,293 - 3,811,509 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197611
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,865,691 - 3,869,952 (+)Ensembl
GRCm38.p6 Ensembl53,815,691 - 3,819,952 (+)Ensembl
RefSeq Acc Id: ENSMUST00000197742
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,862,778 - 3,868,569 (+)Ensembl
GRCm38.p6 Ensembl53,812,778 - 3,818,569 (+)Ensembl
RefSeq Acc Id: ENSMUST00000198079   ⟹   ENSMUSP00000142657
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,854,240 - 3,859,709 (+)Ensembl
GRCm38.p6 Ensembl53,804,240 - 3,809,709 (+)Ensembl
RefSeq Acc Id: ENSMUST00000199234
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,873,158 - 3,875,071 (+)Ensembl
GRCm38.p6 Ensembl53,823,158 - 3,825,071 (+)Ensembl
RefSeq Acc Id: ENSMUST00000199475
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,853,185 - 3,861,716 (+)Ensembl
GRCm38.p6 Ensembl53,803,185 - 3,811,716 (+)Ensembl
RefSeq Acc Id: ENSMUST00000199845
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,853,184 - 3,891,284 (+)Ensembl
GRCm38.p6 Ensembl53,803,184 - 3,841,284 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200004
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,877,538 - 3,881,018 (+)Ensembl
GRCm38.p6 Ensembl53,827,538 - 3,831,018 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200386   ⟹   ENSMUSP00000143559
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,853,190 - 3,895,564 (+)Ensembl
GRCm38.p6 Ensembl53,803,190 - 3,845,564 (+)Ensembl
RefSeq Acc Id: ENSMUST00000200577   ⟹   ENSMUSP00000143776
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl53,853,189 - 3,891,359 (+)Ensembl
GRCm38.p6 Ensembl53,803,189 - 3,841,359 (+)Ensembl
RefSeq Acc Id: NM_001170552   ⟹   NP_001164023
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3953,853,165 - 3,894,515 (+)NCBI
GRCm3853,803,165 - 3,844,515 (+)ENTREZGENE
MGSCv3753,803,165 - 3,844,515 (+)RGD
Celera53,739,452 - 3,780,804 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_030675   ⟹   NP_109600
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3953,853,165 - 3,894,515 (+)NCBI
GRCm3853,803,165 - 3,844,515 (+)ENTREZGENE
MGSCv3753,803,165 - 3,844,515 (+)RGD
Celera53,739,452 - 3,780,804 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_033173
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3953,853,181 - 3,894,515 (+)NCBI
GRCm3853,803,181 - 3,844,515 (+)NCBI
MGSCv3753,803,165 - 3,844,515 (+)RGD
Celera53,739,452 - 3,780,804 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006503617   ⟹   XP_006503680
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3953,853,167 - 3,894,255 (+)NCBI
GRCm3853,803,172 - 3,844,255 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006503618   ⟹   XP_006503681
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3953,853,555 - 3,894,255 (+)NCBI
GRCm3853,803,611 - 3,844,255 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030254911   ⟹   XP_030110771
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3953,853,612 - 3,894,255 (+)NCBI
GRCm3853,803,181 - 3,844,508 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030254912   ⟹   XP_030110772
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3953,853,156 - 3,894,508 (+)NCBI
GRCm3853,803,156 - 3,844,508 (+)NCBI
Sequence:
RefSeq Acc Id: NP_109600   ⟸   NM_030675
- Peptide Label: isoform 1
- UniProtKB: Q9EPY2 (UniProtKB/Swiss-Prot),   Q8C9Q6 (UniProtKB/Swiss-Prot),   Q7TPR8 (UniProtKB/Swiss-Prot),   Q6VSV2 (UniProtKB/Swiss-Prot),   Q9ERH0 (UniProtKB/Swiss-Prot),   Q6S5J6 (UniProtKB/Swiss-Prot),   B2RUA8 (UniProtKB/TrEMBL),   Q5U463 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001164023   ⟸   NM_001170552
- Peptide Label: isoform 2
- UniProtKB: Q5U463 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006503680   ⟸   XM_006503617
- Peptide Label: isoform X1
- UniProtKB: Q9EPY2 (UniProtKB/Swiss-Prot),   Q8C9Q6 (UniProtKB/Swiss-Prot),   Q7TPR8 (UniProtKB/Swiss-Prot),   Q6VSV2 (UniProtKB/Swiss-Prot),   Q9ERH0 (UniProtKB/Swiss-Prot),   Q6S5J6 (UniProtKB/Swiss-Prot),   B2RUA8 (UniProtKB/TrEMBL),   Q5U463 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006503681   ⟸   XM_006503618
- Peptide Label: isoform X1
- UniProtKB: Q9EPY2 (UniProtKB/Swiss-Prot),   Q8C9Q6 (UniProtKB/Swiss-Prot),   Q7TPR8 (UniProtKB/Swiss-Prot),   Q6VSV2 (UniProtKB/Swiss-Prot),   Q9ERH0 (UniProtKB/Swiss-Prot),   Q6S5J6 (UniProtKB/Swiss-Prot),   B2RUA8 (UniProtKB/TrEMBL),   Q5U463 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030110772   ⟸   XM_030254912
- Peptide Label: isoform X2
- UniProtKB: Q5U463 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030110771   ⟸   XM_030254911
- Peptide Label: isoform X1
- UniProtKB: Q9EPY2 (UniProtKB/Swiss-Prot),   Q8C9Q6 (UniProtKB/Swiss-Prot),   Q7TPR8 (UniProtKB/Swiss-Prot),   Q6VSV2 (UniProtKB/Swiss-Prot),   Q6S5J6 (UniProtKB/Swiss-Prot),   Q9ERH0 (UniProtKB/Swiss-Prot),   B2RUA8 (UniProtKB/TrEMBL),   Q5U463 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000142657   ⟸   ENSMUST00000198079
RefSeq Acc Id: ENSMUSP00000132375   ⟸   ENSMUST00000171023
RefSeq Acc Id: ENSMUSP00000078985   ⟸   ENSMUST00000080085
RefSeq Acc Id: ENSMUSP00000143776   ⟸   ENSMUST00000200577
RefSeq Acc Id: ENSMUSP00000143559   ⟸   ENSMUST00000200386
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6S5J6-F1-model_v2 AlphaFold Q6S5J6 1-736 view protein structure

Promoters
RGD ID:6837909
Promoter ID:MM_KWN:41272
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000115493,   NM_001003909,   NM_001170552,   NM_030675,   NM_030675_KRIT1,   NR_033173,   UC008WHQ.1,   UC008WHR.1,   UC008WHS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3653,801,876 - 3,803,717 (-)MPROMDB
RGD ID:6885906
Promoter ID:EPDNEW_M6404
Type:multiple initiation site
Name:Krit1_1
Description:Mus musculus KRIT1, ankyrin repeat containing , transcript variant3, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3853,803,184 - 3,803,244EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1930618 AgrOrtholog
Ensembl Genes ENSMUSG00000000600 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000080085 ENTREZGENE
  ENSMUST00000080085.9 UniProtKB/Swiss-Prot
  ENSMUST00000171023 ENTREZGENE
  ENSMUST00000171023.8 UniProtKB/Swiss-Prot
  ENSMUST00000198079.2 UniProtKB/TrEMBL
  ENSMUST00000200386 ENTREZGENE
  ENSMUST00000200386.5 UniProtKB/TrEMBL
  ENSMUST00000200577.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.80.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.2240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Band_41_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_central UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRIT1_FERM_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDIX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDIX_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:79264 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1930618 ENTREZGENE
NCBI Gene 79264 ENTREZGENE
PANTHER KREV INTERACTION TRAPPED 1-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KREV INTERACTION TRAPPED PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ank_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUDIX_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Krit1 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B41 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JE71_MOUSE UniProtKB/TrEMBL
  A0A0G2JGG7_MOUSE UniProtKB/TrEMBL
  B2RUA8 ENTREZGENE, UniProtKB/TrEMBL
  KRIT1_MOUSE UniProtKB/Swiss-Prot
  Q5U463 ENTREZGENE, UniProtKB/TrEMBL
  Q6S5J6 ENTREZGENE
  Q6VSV2 ENTREZGENE
  Q7TPR8 ENTREZGENE
  Q8C9Q6 ENTREZGENE
  Q9EPY2 ENTREZGENE
  Q9ERH0 ENTREZGENE
UniProt Secondary Q6VSV2 UniProtKB/Swiss-Prot
  Q7TPR8 UniProtKB/Swiss-Prot
  Q8C9Q6 UniProtKB/Swiss-Prot
  Q9EPY2 UniProtKB/Swiss-Prot
  Q9ERH0 UniProtKB/Swiss-Prot