Rnf227 (ring finger protein 227) - Rat Genome Database
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Gene: Rnf227 (ring finger protein 227) Mus musculus
Analyze
Symbol: Rnf227
Name: ring finger protein 227
RGD ID: 1614250
MGI Page MGI
Description: Is expressed in brain and spinal cord. Orthologous to human RNF227 (ring finger protein 227); INTERACTS WITH Benzo[k]fluoranthene; ethanol; sodium arsenate.
Type: ncrna
RefSeq Status: VALIDATED
Also known as: 2310043C11Rik; A030009H04Rik; AA589459; AB041807; Chd3; Chd3os; chromodomain helicase DNA binding protein 3, opposite strand; MNCb-2875; RNF21
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,231,622 - 69,233,467 (+)NCBIGRCm39mm39
GRCm39 Ensembl1169,231,287 - 69,233,467 (+)Ensembl
GRCm381169,340,796 - 69,342,641 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,340,461 - 69,342,641 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,154,271 - 69,156,149 (+)NCBIGRCm37mm9NCBIm37
MGSCv361169,157,012 - 69,158,836 (+)NCBImm8
Celera1176,294,623 - 76,296,499 (+)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068  


Genomics

Comparative Map Data
Rnf227
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,231,622 - 69,233,467 (+)NCBIGRCm39mm39
GRCm39 Ensembl1169,231,287 - 69,233,467 (+)Ensembl
GRCm381169,340,796 - 69,342,641 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,340,461 - 69,342,641 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,154,271 - 69,156,149 (+)NCBIGRCm37mm9NCBIm37
MGSCv361169,157,012 - 69,158,836 (+)NCBImm8
Celera1176,294,623 - 76,296,499 (+)NCBICelera
Cytogenetic Map11B3NCBI
RNF227
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,913,339 - 7,916,289 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl177,913,324 - 7,916,276 (-)EnsemblGRCh38hg38GRCh38
GRCh38177,913,324 - 7,916,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,816,642 - 7,819,636 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,757,365 - 7,760,499 (-)NCBINCBI36hg18NCBI36
Celera177,844,148 - 7,846,772 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,711,229 - 7,713,853 (-)NCBIHuRef
CHM1_1177,825,419 - 7,828,044 (-)NCBICHM1_1
Rnf227
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21054,061,054 - 54,061,726 (+)NCBI
Rnor_6.0 Ensembl1055,940,533 - 55,941,205 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01055,940,533 - 55,941,205 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01055,681,368 - 55,684,924 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,133,424 - 56,134,096 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1053,217,612 - 53,218,284 (+)NCBICelera
Cytogenetic Map10q24NCBI
RNF227
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,936,179 - 7,937,736 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,936,179 - 7,937,723 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,948,370 - 7,951,882 (-)NCBIMhudiblu_PPA_v0panPan3
RNF227
(Canis lupus familiaris - dog)		 No map positions available.
RNF227
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,163,863 - 53,166,567 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,163,996 - 53,166,418 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,524,899 - 55,532,596 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RNF227
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,296,538 - 7,304,941 (-)NCBI

Position Markers
RH124968  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381169,341,625 - 69,341,776UniSTSGRCm38
MGSCv371169,155,127 - 69,155,278UniSTSGRCm37
Celera1176,295,479 - 76,295,630UniSTS
Cytogenetic Map11B3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115936579169591873Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116910000072600000Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116910000072600000Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116910000072600000Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116910000072600000Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116910000072600000Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116910000072600000Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116910000072600000Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116910000072600000Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116910000072600000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:161
Count of miRNA genes:144
Interacting mature miRNAs:157
Transcripts:ENSMUST00000129321, ENSMUST00000151617
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000129321   ⟹   ENSMUSP00000146712
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1169,340,461 - 69,342,641 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151617   ⟹   ENSMUSP00000147159
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1169,340,809 - 69,341,375 (+)Ensembl
RefSeq Acc Id: ENSMUST00000218008   ⟹   ENSMUSP00000151352
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1169,340,771 - 69,341,896 (+)Ensembl
RefSeq Acc Id: NR_027827
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,231,622 - 69,233,467 (+)NCBI
GRCm381169,340,796 - 69,342,641 (+)NCBI
MGSCv371169,154,271 - 69,156,149 (+)RGD
Celera1176,294,623 - 76,296,499 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
GenBank Protein BAA95115 (Get FASTA)   NCBI Sequence Viewer  
  BAB22482 (Get FASTA)   NCBI Sequence Viewer  
  BAK18564 (Get FASTA)   NCBI Sequence Viewer  
  EDL10494 (Get FASTA)   NCBI Sequence Viewer  
  Q9DCB3 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: ENSMUSP00000151352   ⟸   ENSMUST00000218008
RefSeq Acc Id: ENSMUSP00000147159   ⟸   ENSMUST00000151617
RefSeq Acc Id: ENSMUSP00000146712   ⟸   ENSMUST00000129321
Protein Domains
DUF4632   RING-type

Promoters
RGD ID:8675168
Promoter ID:EPDNEW_M15615
Type:initiation region
Name:Chd3os_1
Description:Mus musculus chromodomain helicase DNA binding protein 3, oppositestrand , long non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381169,340,796 - 69,340,856EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915359 AgrOrtholog
Ensembl Genes ENSMUSG00000043419 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000146712 UniProtKB/Swiss-Prot
  ENSMUSP00000147159 UniProtKB/TrEMBL
  ENSMUSP00000151352 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000129321 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000151617 UniProtKB/TrEMBL
  ENSMUST00000218008 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DUF4632 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1915359 ENTREZGENE
NCBI Gene 80515 ENTREZGENE
Pfam DUF4632 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-RING_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnf227 PhenoGen
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RNAcentral URS0001BBE418 RNACentral
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140LJC4_MOUSE UniProtKB/TrEMBL
  A0A338P5U3_MOUSE UniProtKB/TrEMBL
  F1SW11_MOUSE UniProtKB/TrEMBL
  Q9DCB3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A140LI80 UniProtKB/Swiss-Prot
  Q9JJ82 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-29 Rnf227  ring finger protein 227  Chd3os  chromodomain helicase DNA binding protein 3, opposite strand  Symbol and/or name change 5135510 APPROVED
2013-11-26 Chd3os  chromodomain helicase DNA binding protein 3, opposite strand    Chd3 opposite strand transcript  Symbol and/or name change 5135510 APPROVED
2013-11-19 Chd3os  Chd3 opposite strand transcript  A030009H04Rik  RIKEN cDNA A030009H04 gene  Symbol and/or name change 5135510 APPROVED