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Gene: Ucn2 (urocortin 2) Mus musculus
Symbol: Ucn2
Name: urocortin 2
Description: This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. Mice lacking the encoded protein exhibit increased insulin sensitivity and were protected against fat-induced insulin resistance. In addition, female mice lacking the encoded protein exhibit a significant increase in the basal daily rhythms of adrenocorticotropic hormone and corticosterone, and a significant decrease in fluid intake and depressive-like behavior. [provided by RefSeq, Sep 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Ucn II; Ucn-2; ucn-II; Urocortin II; urocortin-2
Homo sapiens (human) : UCN2 (urocortin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ucn2 (urocortin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ucn2 (urocortin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : UCN2 (urocortin 2)
Canis lupus familiaris (dog) : UCN2 (urocortin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ucn2 (urocortin 2)
Sus scrofa (pig) : UCN2 (urocortin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389108,986,163 - 108,987,164 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379108,888,208 - 108,889,209 (+)NCBIGRCm37mm9NCBIm37
Celera9108,544,152 - 108,545,153 (+)NCBICelera
Cytogenetic Map9 F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ucn2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1614218
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.