Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ucn2 (urocortin 2) Mus musculus
Analyze
Symbol: Ucn2
Name: urocortin 2
Description: This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. Mice lacking the encoded protein exhibit increased insulin sensitivity and were protected against fat-induced insulin resistance. In addition, female mice lacking the encoded protein exhibit a significant increase in the basal daily rhythms of adrenocorticotropic hormone and corticosterone, and a significant decrease in fluid intake and depressive-like behavior. [provided by RefSeq, Sep 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Ucn II; Ucn-2; ucn-II; Urocortin II; urocortin-2
Orthologs:
Homo sapiens (human) : UCN2 (urocortin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ucn2 (urocortin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ucn2 (urocortin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : UCN2 (urocortin 2)
Canis lupus familiaris (dog) : UCN2 (urocortin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ucn2 (urocortin 2)
Sus scrofa (pig) : UCN2 (urocortin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389108,986,163 - 108,987,164 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379108,888,208 - 108,889,209 (+)NCBIGRCm37mm9NCBIm37
Celera9108,544,152 - 108,545,153 (+)NCBICelera
Cytogenetic Map9 F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Ucn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1614218
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.